Hhel026460.1
Basic Information
- Insect
- Helleia helle
- Gene Symbol
- -
- Assembly
- GCA_963853865.1
- Location
- OY971434.1:4298530-4315094[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.81 86 4.8 0.2 1 23 311 334 311 334 0.94 2 10 4.5 4.8e+02 2.4 0.4 8 23 347 362 342 363 0.79 3 10 0.024 2.5 9.6 2.7 1 23 434 457 434 457 0.95 4 10 2.7e-05 0.0029 18.8 3.1 2 23 462 483 461 483 0.97 5 10 0.0049 0.52 11.7 0.6 2 23 491 511 491 511 0.98 6 10 3e-05 0.0032 18.7 2.0 1 21 517 537 517 542 0.94 7 10 0.00092 0.098 14.0 0.3 1 23 550 573 550 573 0.94 8 10 1.9e-05 0.002 19.3 0.2 1 23 579 602 579 602 0.97 9 10 2.6e-05 0.0028 18.9 0.5 1 23 612 634 612 634 0.94 10 10 2.9e-05 0.0031 18.7 2.9 2 23 641 663 640 663 0.96
Sequence Information
- Coding Sequence
- ATGGAGCAAGATGTTGACGATGAATATAAACCTGTGTGCTGTGCGTGCCTTAGTACCGATCGCAATTTAGTTGCATTAAATAGTTTAATTGAAGTTGTGGAAGTTTTTAAATTGTTAACATACAGTTTTGTGGAAGATAGGataatagATACTGAAATGGGACTGAAACAACTGGTGTGCTGGGAGTGCTTTGCAATCATGAAGAAATTTGCTAGATTCAAGAGACAGGTTCAAAATGCACAAGAACATCTGCGAATTATCACAATTGGAAATGCATTAGAGATTATGGATCATACTTATCTATCCCAATCTCTGTCGTCGCTGGAGTGTGTAATAAAGCCTGACTATGACAGAATGTACATTGACTACACTCATGAAATACCGTCTACCGCTGAAGACTGGCCACAGCAATATATATCAATTACGGATGATTTGAAACCTCAGGAATATGATGTTGCGCAGACTTTAAGAGAAAATATCACACTTGGTATTGATGATCGGGTACTTGAAATGCCAGAAATAGTAGTGGAGAACCCAATGACAGGAGTCATGTCTCACATTGTTGTGGGTGATCCATGTGTTGATACTGTGTATATATCTTTGTTAAGTGTAGCCCCACATTTTAGTGCCAGAAATATGCCAGAAATAGTAGTGGAGAACCCAATGACAGGAGTCATGTCACACATTGTTGTGGCTGATCCGCTCAAAGAAACGTTCACCGGAACCACTGTAAAGGGTGAATTGCCTGAACTCATTTTGGGTACAACATCTTCAGGCTCAGTAATAATTAAGCAAAATTTAAAAGGAAAGAATAAAGTCAAAGATGAGGAAAAGCTAAAGAGTGGTTATGTCGTGGAGTACATGTGTGAAGCGGACATGATGGCTATGAGAGAGGAAGAGAAGAAGAAAGTGCAATACGCCAGTGCAGTGTACAAGTGCGAGCTCTGCATCATCGGCTTCTACAACCAGCAGCAAGTCGAGGACCATTTTCTCTCCGTACATCGACCTCGGCCCGGCTACGCGCCGTGCAAGGTGTGCTACGTGTACACGGAGGCGAGCAAGCTGTCGGCGCACCAGGACTCGCACCACCTGCTGTACTTGTGTCGACTGTGCGACCGCCGCGAGCGGACCGCGCGCGCCATCGCGCACCACGTGGCCGCGCACCTCGCGCGCCAGCCGCCCAGCGCGCAGATCAACATCGATGACGCTACACCTAAGAAGAAACAAAAGGACTCTGACAAGCCAGGACCGAAGCCCGGTGACCTGAGGAAGCTGCTCTCTAAGACTACAATTGTGGGATACAAATGTTTGGAGTGTGATGCCTTTTTcaaGAATTCTAGGGCACGTAAGAGTCACGTGGCCCGCTGTCACAGAGAGGGACTACAGTGTGACCATTGCAAAAAGAGATTTGTTAACAGGACGACACTGGCAACACATCTCAGGTTGCACGAGGGCCCGCTGCCCCGCGAGAAGTGTCCCATCTGCAACAAGATGGTCCGTCTCATCCAGCTGAAATACCACATCCAGCGGCACCAGAACACCAAGCGGTACGAGTGCAAGGACTGCAACAAGGTGTTCTCCCACCTCACCACCTATCAGGCGCACCTCAAGTACTCCCGGCCGCACGCCTCGGACCAGGTCTTCAAGTTCCCATGCCCAATGTGTAACAAGGGCTACCCGACCAAGGAGGCGATGCAGGACCACTTCAATTACCAACACCTCGGGAAAACTACACACAAATGTCCCATATGTAATAAGCCGATAGCTTCAAAAGCGAATGTGGAAAGGCATATGATGAGAGTACACGGAGAGAAGAAGGAAAAACCGAGAACACATGTGTGTCAGCAGTGCGGAAAGGCCTTCACTGACAAGAAGGCACTAAGTCAGCACGCGGTGATCCACTCGGTGGAGCGGCCGCTGTCGTGCGACATCTGCCACCAGACATTCAAGCAGAAGGCGTCGCTGTACACACACAGGAGGCGCGTGCACAAGGTCTCGCCGGCCAAGCGGGTAGTCGAGTTTATGGACCACCTCGAGGGCTAG
- Protein Sequence
- MEQDVDDEYKPVCCACLSTDRNLVALNSLIEVVEVFKLLTYSFVEDRIIDTEMGLKQLVCWECFAIMKKFARFKRQVQNAQEHLRIITIGNALEIMDHTYLSQSLSSLECVIKPDYDRMYIDYTHEIPSTAEDWPQQYISITDDLKPQEYDVAQTLRENITLGIDDRVLEMPEIVVENPMTGVMSHIVVGDPCVDTVYISLLSVAPHFSARNMPEIVVENPMTGVMSHIVVADPLKETFTGTTVKGELPELILGTTSSGSVIIKQNLKGKNKVKDEEKLKSGYVVEYMCEADMMAMREEEKKKVQYASAVYKCELCIIGFYNQQQVEDHFLSVHRPRPGYAPCKVCYVYTEASKLSAHQDSHHLLYLCRLCDRRERTARAIAHHVAAHLARQPPSAQINIDDATPKKKQKDSDKPGPKPGDLRKLLSKTTIVGYKCLECDAFFKNSRARKSHVARCHREGLQCDHCKKRFVNRTTLATHLRLHEGPLPREKCPICNKMVRLIQLKYHIQRHQNTKRYECKDCNKVFSHLTTYQAHLKYSRPHASDQVFKFPCPMCNKGYPTKEAMQDHFNYQHLGKTTHKCPICNKPIASKANVERHMMRVHGEKKEKPRTHVCQQCGKAFTDKKALSQHAVIHSVERPLSCDICHQTFKQKASLYTHRRRVHKVSPAKRVVEFMDHLEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00926066;
- 90% Identity
- -
- 80% Identity
- -