Basic Information

Insect: Helicoverpa zea
Gene Symbol: CTCF
Assembly: GCA_002150865.1
Location: KZ118116.1:10268-43843[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0031 0.22 12.2 5.8 1 23 170 192 170 192 0.99

2 9 0.00025 0.017 15.6 1.3 1 23 198 220 198 220 0.98

3 9 7e-05 0.0049 17.3 1.7 1 23 226 249 226 249 0.96

4 9 0.03 2.1 9.1 3.3 1 21 255 275 255 277 0.95

5 9 0.0001 0.0074 16.8 2.7 1 23 283 305 283 305 0.99

6 9 9.9e-06 0.0007 20.0 3.2 1 23 311 333 311 333 0.98

7 9 3.6e-05 0.0026 18.2 2.0 1 23 356 378 356 378 0.98

8 9 1.9e-05 0.0013 19.1 1.7 1 23 384 407 384 407 0.93

9 9 1.1e-05 0.00076 19.9 4.4 1 23 421 443 421 443 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0031	0.22	12.2	5.8	1	23	170	192	170	192	0.99
2	9	0.00025	0.017	15.6	1.3	1	23	198	220	198	220	0.98
3	9	7e-05	0.0049	17.3	1.7	1	23	226	249	226	249	0.96
4	9	0.03	2.1	9.1	3.3	1	21	255	275	255	277	0.95
5	9	0.0001	0.0074	16.8	2.7	1	23	283	305	283	305	0.99
6	9	9.9e-06	0.0007	20.0	3.2	1	23	311	333	311	333	0.98
7	9	3.6e-05	0.0026	18.2	2.0	1	23	356	378	356	378	0.98
8	9	1.9e-05	0.0013	19.1	1.7	1	23	384	407	384	407	0.93
9	9	1.1e-05	0.00076	19.9	4.4	1	23	421	443	421	443	0.97

Sequence Information

Coding Sequence: ATGGCACCCCCTGATAAAAAGGACAGCACCAAACAAGCTATCATTCCATATACAACAGCTGTTATAACAGTTGCTGGGGCCGAGGATGAAGCTGATTCCGGTGTCGCTTACTTTGTAGATGAAGATGGCAGGTACTACTACCAGCCCACGGTTGAGGGCCAAGAGTTTGTGATGAACAACCAGACTACCAGCCAGGATACTGAGCAGGGAACACAAGAATCAGACACAATGTTGACAGATCAAGAAGCAGAGGGCTATCAAACTGTGACCCTCGTCCCATCGGAGACGAATGGAGAAGTCAGCTATGTGCTAGTCGTGCAAGAGGAGAATAAAGCTATGGTCAATATTGATCTCAAGGTGGACCAGAGCGAGGCCGGTGAGAAAGGCAATGACGATGTGTACAACTTTGAGGAGGAAGAGGCGGGAGAAGAGGCTTCGGAGGAAGAAGATGATGTTCCTGAAGGAAGGCCCAAGCCACAGAAGAAGAACAAGCATACTAGGTTGAACTTCCAGTGCAACTTCTGTTCCTATACTAGTCATCGACGGTACCTGCTCCTTCGTCACATGAAGTCCCATTCGGATGAACGTCCTCACAAGTGCATGGTGTGTGAACGCGGCTTCAAGACCATGGCTTCCCTGCAGAACCATGTGAACATGCACAATGGCGTCAAGCCGCATGTTTGCAAGTACTGCAACAGTCCTTTTACTACTTCTGGGGAGCTGGTGCGTCACGTCCGTTACAAGCACACGCATGAGAAGCCTCACAAATGTACGGAATGCGACTACGCCTCCGTCGAGCTGTCCAAGTTGCGTCGCCATGTTCGCTGTCACACTGGCGAAAGACCTTACCAGTGCCCGCACTGCACGTATGCATCTCCCGACACGTTCAAGCTGAAACGTCATCTGCGCACTCACACCGGCGAGAAGCCTTACAAGTGTGAAAACTGTAATATGTGCTTCACGCAGTCGAACTCTCTGAAAGCGCATCGCCTGATACACAACGCAAGCATTGACAAGTTACCAACTATATCTTTTCTGTTACAGACCCACGAGGGCGAGAAATGCTTCAAGTGTGAGATCTGCCCGTACGCTTCGACGACTCTGCGTCACTTGAAGTCACACATGCTGAAGCACACTGATGAGAAGCCCTTCCTCTGTGATCTCTGCGATCAGTCCTTCAGGCAGAAGCAACTGCTCCGCCGTCACCAGAATCTGTACCACAATCCCGACTACGTGCCGAAGCCGCCCAAAGAGAAGAATCATACTTGCCACGAGTGCAAACGCATGTTCGCGCACAAGGGTAACCTGATCCGTCACTTGGCTGTCCACGACCCGGAGTCTGGGCACCAGGAGCAGGCCCTCGCCCTCAAGATCGGGAGACAGAGGAAAGTCAAGTTCCTCGATGCGGAGCCTAGTAGGGATATACGTGTGGTGGACCCGACCAATGCATCGGAGATGATGAAGCTCGGCCTCGCCAACAACGAGATGAAGAGAGGCGAGCTGGTCACCGTGACGGACGGCGACGGACAGCAGTACGTCGTGCTGGAGGTCATCCAACTGGAGGACGGCACCGAGCAGCAAGTGGCGGTTGTTGCACCTGATTACATGGAAGAGGATGCGCAGGAAGAGGGTGAAGAAGAAGAGGAGGAGGAGGAAGAGGAGGAAGGGGACGCAGAAATGAGCTACGGAGGTAAAAGCTCAGAGAATGACAACAACATCAAGCTCGAGAAGGAGGTCGATAGCTGCTTCGGTTTTGATGTCGGAAGAAAGACGAAGCTTCGTTTACTGCCCGTGCCGCCTCGAGTGGCCTGTGTGGAAACCCCGGACTCTCCTAGGGTTCATCCAATTCtgtgtttgaaaaaatataaacgcAAACGTTCGGCGCCATCTAGCACGGAGGTTAGCAGCTCTAATGCAGAGGCCAGCAGCTCTAATACAGAGGTTACCAGCTCAGAGCCTCGGCTTACAGTCAGCGTAGACATTAGCTCCGCAGACGAAAATGTTGAGCCAAATGATGAGCTCTACCACGTTAAGCACAAACTAACTGTACCTTTGGCAAGGATCAGTACTGTTTGCGAAACGAAGGTGGAATGGGAAAGGAGATTTGGGCCACCGGCACTCGTCACCAACCACAAGGTCATCACCCCAAGTTGGTTTAGTGAGCGAGCGTGGTACTTCCCCGGTCGAGCCAGCCCAGAAGAATTTGTGCAAGGAAGGGTGCAGATGAGGATAGTCGGAGGTGAAACTGGGATTGGGGAGAGAATGAAGGAAAGAAGGCTAGTAAGGATAGACGAGAGGACAAAAGATATGCAGGGAAAGGAAGGAAGGAAAGTAGGCCGTCGGAACTCGCATTCACCGAACGAAACACAGTAG
Protein Sequence: MAPPDKKDSTKQAIIPYTTAVITVAGAEDEADSGVAYFVDEDGRYYYQPTVEGQEFVMNNQTTSQDTEQGTQESDTMLTDQEAEGYQTVTLVPSETNGEVSYVLVVQEENKAMVNIDLKVDQSEAGEKGNDDVYNFEEEEAGEEASEEEDDVPEGRPKPQKKNKHTRLNFQCNFCSYTSHRRYLLLRHMKSHSDERPHKCMVCERGFKTMASLQNHVNMHNGVKPHVCKYCNSPFTTSGELVRHVRYKHTHEKPHKCTECDYASVELSKLRRHVRCHTGERPYQCPHCTYASPDTFKLKRHLRTHTGEKPYKCENCNMCFTQSNSLKAHRLIHNASIDKLPTISFLLQTHEGEKCFKCEICPYASTTLRHLKSHMLKHTDEKPFLCDLCDQSFRQKQLLRRHQNLYHNPDYVPKPPKEKNHTCHECKRMFAHKGNLIRHLAVHDPESGHQEQALALKIGRQRKVKFLDAEPSRDIRVVDPTNASEMMKLGLANNEMKRGELVTVTDGDGQQYVVLEVIQLEDGTEQQVAVVAPDYMEEDAQEEGEEEEEEEEEEEGDAEMSYGGKSSENDNNIKLEKEVDSCFGFDVGRKTKLRLLPVPPRVACVETPDSPRVHPILCLKKYKRKRSAPSSTEVSSSNAEASSSNTEVTSSEPRLTVSVDISSADENVEPNDELYHVKHKLTVPLARISTVCETKVEWERRFGPPALVTNHKVITPSWFSERAWYFPGRASPEEFVQGRVQMRIVGGETGIGERMKERRLVRIDERTKDMQGKEGRKVGRRNSHSPNETQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -