Basic Information

Insect: Heliconius sara
Gene Symbol: -
Assembly: GCA_917862395.2
Location: OU860798.1:4736078-4737205[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.081 6 7.9 2.6 1 22 156 177 156 180 0.90

2 7 0.056 4.1 8.5 1.2 2 20 186 203 185 206 0.72

3 7 9.4e-07 7e-05 23.5 0.4 1 23 212 234 212 234 0.98

4 7 5.8e-05 0.0043 17.8 1.6 1 23 240 262 240 262 0.99

5 7 6.9e-07 5.1e-05 23.9 0.9 1 23 268 290 268 290 0.99

6 7 0.00029 0.021 15.7 1.0 1 23 296 319 296 319 0.96

7 7 4.9e-05 0.0036 18.1 1.6 1 23 325 348 325 348 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.081	6	7.9	2.6	1	22	156	177	156	180	0.90
2	7	0.056	4.1	8.5	1.2	2	20	186	203	185	206	0.72
3	7	9.4e-07	7e-05	23.5	0.4	1	23	212	234	212	234	0.98
4	7	5.8e-05	0.0043	17.8	1.6	1	23	240	262	240	262	0.99
5	7	6.9e-07	5.1e-05	23.9	0.9	1	23	268	290	268	290	0.99
6	7	0.00029	0.021	15.7	1.0	1	23	296	319	296	319	0.96
7	7	4.9e-05	0.0036	18.1	1.6	1	23	325	348	325	348	0.95

Sequence Information

Coding Sequence: atggTAGGACAccttatgttattaaaaatattacactgcAAATTGCACAAACGccgaaaaatattaaacaatgaaaaaaaagattCGCCGTGTTTACCTGAACCTGAAACATCGCCGGTTAAGAAAGAAACAAACGAGTTTGATGATCATCAACAAACATGTAGGGTTTGCTTAAAAGAAGGTGACGTTCCTATTTTCGGTAATGAAGTATCAGAAGATATTTCAGAAAAACTTATATCCTTCACAGCCATCGAAATTAACCCCTACGATAACTATCCGAAATTTCTCTGTCAGTCTTGTTACGCTCTTCTCCAAGGTgccattttactaaaaaaaactgcACACCAATCGAATATATTGTTACAGCAACCTCACCAAGATATatcagataatgaaaataattttaatgcaaCCGATAATTTtgatacatataatattgaaacatttaaagaacaaaataatgacTACCATTGTAAGAAATGTTCCTTAAGCTTTGAATCATTTAATGACTATAGTGATCATAGACTTTCGGAAGAACATGAAAATATGAGACAAACTTGTCCAATTTGCAATAAATCCTATGCTACACTTTATTTTAAGCGACATTTAGCTTTACACAAAGTAGATACCTCGTACATGTGTGATATATGTGGAAAAAAGTTTATAGTACAAGGACAATTTGCCAGACATAGGATGACTCACTTTTACAATTTACCTTTCAAATGTTCAGTTTGTCCATATAGAGGTAGATTTAAAGAGTCACTCAAAATGCACATGCGGTCACACACTGGTGAGAAACCATACCAATGTAGTCAATGTCCAGgaaagtttgtaaataaaagtaatttaaacaaACATCTTTTAACTCATAAAGGAGATCATGATTTTAAATGTGAGTCCTGTGGTCGAGGGTTTTATACTAAAAGAGACTtggatttacattttaaagttgaCCATACAGGCATTAAAGACCATATATGTAGTGAATGTGGCAAAGCATTTGGTTACAGGAAGCAGATGATGAAACATCAACTAAAAGTTCACAAAAGGGAGAAATTAAAGAGTGGTAGAATGCCCTTGTATTTACAATTAGAGTGTAAGAAACAATTAGCAATTGAACCAGAATAG
Protein Sequence: MVGHLMLLKILHCKLHKRRKILNNEKKDSPCLPEPETSPVKKETNEFDDHQQTCRVCLKEGDVPIFGNEVSEDISEKLISFTAIEINPYDNYPKFLCQSCYALLQGAILLKKTAHQSNILLQQPHQDISDNENNFNATDNFDTYNIETFKEQNNDYHCKKCSLSFESFNDYSDHRLSEEHENMRQTCPICNKSYATLYFKRHLALHKVDTSYMCDICGKKFIVQGQFARHRMTHFYNLPFKCSVCPYRGRFKESLKMHMRSHTGEKPYQCSQCPGKFVNKSNLNKHLLTHKGDHDFKCESCGRGFYTKRDLDLHFKVDHTGIKDHICSECGKAFGYRKQMMKHQLKVHKREKLKSGRMPLYLQLECKKQLAIEPE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00774747;
90% Identity: iTF_00457501;
80% Identity: -