Basic Information

Insect: Heliconius numata
Gene Symbol: zfh1
Assembly: GCA_016802625.1
Location: JAEBDU010000037.1:243238-254722[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.00013 0.013 16.6 1.7 1 23 384 407 384 407 0.95

2 7 0.0016 0.16 13.2 1.7 1 23 576 598 576 598 0.97

3 7 4.2e-05 0.0042 18.2 0.4 2 23 604 625 604 625 0.97

4 7 1e-05 0.001 20.1 1.6 2 23 632 654 631 654 0.93

5 7 4.6e-07 4.6e-05 24.3 1.3 1 23 660 682 660 682 0.99

6 7 4.9e-05 0.005 17.9 2.6 1 23 688 710 688 710 0.99

7 7 9.2e-08 9.3e-06 26.5 1.7 1 23 716 738 716 738 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.00013	0.013	16.6	1.7	1	23	384	407	384	407	0.95
2	7	0.0016	0.16	13.2	1.7	1	23	576	598	576	598	0.97
3	7	4.2e-05	0.0042	18.2	0.4	2	23	604	625	604	625	0.97
4	7	1e-05	0.001	20.1	1.6	2	23	632	654	631	654	0.93
5	7	4.6e-07	4.6e-05	24.3	1.3	1	23	660	682	660	682	0.99
6	7	4.9e-05	0.005	17.9	2.6	1	23	688	710	688	710	0.99
7	7	9.2e-08	9.3e-06	26.5	1.7	1	23	716	738	716	738	0.98

Sequence Information

Coding Sequence: ATGAGGAACGTGGAGGCGCATCTTTTGGGAGATAAAATGGATGAAGCGGTTACGCATTATATCAACTCGCATCAACCACCAGAGTCTGTCCATGTAGATGCAAATTCCTTAGCATTAAATGTGCAGGATGATACTGGAGGAAGAGTGGTTACAGTAATGCATCCTCAGAATTTTCCACCTCAAATGTGCAGGCAAGTATCAGTAGTAGAAGGGGCATGGGTAGAGGATCTGTTAGACCCTGAAAGTAGATTAGCAGCATTGGTGGCACATCTGGCAGAACACTCCAGGTCTAATCATCATATACCTCATGGGCACAGTAAGGTGCCTATAAGAAGTGATGTAGATGCATCAGTTATTTTAGACGCGCCTATGAGATTGTTCAATGGACAGACTTTGGAACATCAACAGGAGTCAATTGTAGTGGAAGTGCCTCCTTTACCACCATTACCGCCATTACAAGACATGAAGCGATGTCCGGAAACTGACTGGTTTAGCAAAGACAAGGGGAGTTTGAAGGATGACCAACAAATACTAGGCCAAAACAGTCAAGTGCTAGACATGGGTGCGTCTCAAAAGCAACACAGCAAGAAGAGTTTGCCACATAAGAAAAGGATATCAAGGAAACTAAAGAGGAATGGATGCAGTACCCCACAGCAGGATATCGTGGTAATAAACTGCAATGAAGAAGTCCAACAAGAAGAGATTCTGCCGGACAACTTTGTTGCCGCTGTGCAGCATACGGATATGCCAGAAGACACTCATCACATAAATCATGAGATGCGTCCGTTGTTCATATGTCAAATATGCGGGGAGTTCTATGGAGACGAGCAGTTAAAGTTCTATCAGCACTTGAAACATCACTATGAACCCGCCATCACCATTATAGAGAATCCTGTACCTGATTTGGGGATTGATAAGATGACAAACACTTGTATAGTAGACAACGTGCCCACATTACCAGATTCAATAGTAGAGCTCTCATTAGAAAACACAGTACCAAAGACAATGTACCAGCCCATAGACAAACATATTCTATACACGTCCAGTGATAAAACACTAAATTACAACACTAAAGTATATCAAACCATAGACAAGGAGGCAGATAGTGATAAAAATGATATCTATAGAGATTTGGATAAACTAGAGATGTATTTCTGCGCAAAGTGTAATAAGACCTTCAGGAAGCAGAAGCAATATGAAGTGCATTTGAATGAAGCTCATAGTAATTCGAAGATAGAGGAAATGAACGAGTTCAGTGAGCCCGAGGACCTGATGGAGGGCATCCACGTCGCCGTGGAGGAGGGCGAGGCCTACGAGCATGTGCTGCCGCACCTTATCGTGGAGAACGGACACGTGCACCAGGAGCACGTCAGGCAGTGGTACCTCCGCAACACGGCGACCCCGCCGCCCGCCGCCGTGTCACCACTGTGCGCGTGCGCCGGCGCCGGCTTCTGCGCGACGTGTGCGTGCGCGCCCCTCCCGCCCGCGCCTGCCCCGCCCCCCGCCGCACCTGCCTCTCCCGCCGCTAGACAGGAGAAGGAAGAAAGTTTACAACGGATATTCGAACAAGACCAACAAGATGACCAAACATTCACATCAAACGAAACTCAAACTCAAAATCAAACTCAAATTAAATCTAAATCTATGGAAAGTCCAATCCAAGTTAAAATCGAGCCGGGAATCGAACCTAAGAACAGTAAAAAGAAAGGACAAGGAAACAAGATCTTTAAATGTACGCCATGTGACAAAGTATTCGCACATAAAAACAGTTTGTTATACCATGAGTTGATGCACGACGAGAAGAAGGAGGTCTGTCGAGATTGTGGGAAGAAGTTTTATACTGTTGGTGCTCTGAAGGTTCACAAAAGAATGCACAATGGCGATCGTCCGTGCAAGTGCGACGAGTGCGGCCGCGAGTTTAGGCAGTGGAGCGACCTTAAATATCATAAAGCGTCTATACATTCTAGTCATAAGGAATACAAATGCGATTTCTGCGGTAAAGAATTCGCTCGCCGCTACTCGCTTAACATTCACCGTCGTATACACACCGGCGAGAGGAAGTACAAGTGCGACTACTGTACGAAGACCTTCCGGGCGTCCTCCTATAGGCTGAGCCATATGAGGATACATACTGGTTGCAAACCCTACAAATGTACCTATTGTGATAAATCTTTCCGTGTATCTTACGATTTAAGGCGACATATGGCTTTACATGAAAAAGCCCGTATAATAGTCGGCGATACCAAGAAAAATAAAGATGATATTGACAAAAAAACTATTACGCCAAAACCAGGTGAAACTAAAAATGATAAAAATAATATTGAAGATAAGAAAGAAACATCGAGATTACCAGTTCTGAGGACTTTGTTAGATAAAAAAGTTACATTACCAAAGAAATCGCCTAAAAAAGTGCGGAATGTTACAATTCAAAATCGTGATTTTAAAATCAATGATTATGAACTATTAGAAAGGCAAGAACAATATAAATTTAAAGAAGTTTACACACAAAAAGATATATATACAGAAGAAATGAGGTTAGACCGAAATGAAGACCGAGATCTAGGTTTAAGACAAAAAAAACAAAATGAAGATGATCGCTTAGCTTACAGAGGAAATACAGACGGTAAAATGCATGTTTATACACAAATAGATAAAACTAAAGACTATGAAGGTCCTATAGTGACCAATACGGTGTCTTTGAGTGAACTAAGAAATATAGACAAAGATGTAAGGGAGCCTAGGACTGAGTTACATGGTGAAAGTATAGAGAATGGCTTCTTCGAAAGACTTTCAGCATTTTATAATATTCCGGCTGTATGA
Protein Sequence: MRNVEAHLLGDKMDEAVTHYINSHQPPESVHVDANSLALNVQDDTGGRVVTVMHPQNFPPQMCRQVSVVEGAWVEDLLDPESRLAALVAHLAEHSRSNHHIPHGHSKVPIRSDVDASVILDAPMRLFNGQTLEHQQESIVVEVPPLPPLPPLQDMKRCPETDWFSKDKGSLKDDQQILGQNSQVLDMGASQKQHSKKSLPHKKRISRKLKRNGCSTPQQDIVVINCNEEVQQEEILPDNFVAAVQHTDMPEDTHHINHEMRPLFICQICGEFYGDEQLKFYQHLKHHYEPAITIIENPVPDLGIDKMTNTCIVDNVPTLPDSIVELSLENTVPKTMYQPIDKHILYTSSDKTLNYNTKVYQTIDKEADSDKNDIYRDLDKLEMYFCAKCNKTFRKQKQYEVHLNEAHSNSKIEEMNEFSEPEDLMEGIHVAVEEGEAYEHVLPHLIVENGHVHQEHVRQWYLRNTATPPPAAVSPLCACAGAGFCATCACAPLPPAPAPPPAAPASPAARQEKEESLQRIFEQDQQDDQTFTSNETQTQNQTQIKSKSMESPIQVKIEPGIEPKNSKKKGQGNKIFKCTPCDKVFAHKNSLLYHELMHDEKKEVCRDCGKKFYTVGALKVHKRMHNGDRPCKCDECGREFRQWSDLKYHKASIHSSHKEYKCDFCGKEFARRYSLNIHRRIHTGERKYKCDYCTKTFRASSYRLSHMRIHTGCKPYKCTYCDKSFRVSYDLRRHMALHEKARIIVGDTKKNKDDIDKKTITPKPGETKNDKNNIEDKKETSRLPVLRTLLDKKVTLPKKSPKKVRNVTIQNRDFKINDYELLERQEQYKFKEVYTQKDIYTEEMRLDRNEDRDLGLRQKKQNEDDRLAYRGNTDGKMHVYTQIDKTKDYEGPIVTNTVSLSELRNIDKDVREPRTELHGESIENGFFERLSAFYNIPAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00778254;
90% Identity: iTF_00780508;
80% Identity: -