Hmel018393.1
Basic Information
- Insect
- Heliconius melpomene
- Gene Symbol
- -
- Assembly
- None
- Location
- Hmel217001o:14233061-14235920[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.3 21 5.9 0.6 1 20 248 267 248 269 0.94 2 10 0.038 2.6 8.8 0.3 2 23 298 320 297 320 0.95 3 10 0.00018 0.012 16.1 0.2 1 23 343 365 343 365 0.98 4 10 0.00018 0.013 16.1 0.2 1 23 369 392 369 392 0.96 5 10 0.012 0.81 10.4 0.8 1 14 397 410 397 411 0.91 6 10 0.006 0.42 11.3 1.1 2 23 427 449 426 449 0.91 7 10 0.00086 0.06 13.9 1.9 1 23 456 479 456 479 0.98 8 10 0.032 2.2 9.0 2.9 2 23 486 507 485 507 0.97 9 10 4.2e-06 0.00029 21.2 3.8 1 23 513 535 513 535 0.99 10 10 6.1e-05 0.0043 17.5 1.4 1 23 541 563 541 564 0.95
Sequence Information
- Coding Sequence
- ATGGAAAATAATTTGAACAGTACTCGGTTTGGTAAATGCAGATTTTGCTTCAGCAAAGGAAATCATAGAGATATTATGAAAGAGTACAACTGGAACGGCGTATCTGAGATTTATTTCGATGTATTTCAAGAATGCTTCAATTTATATTTATGCACAAATGGGAGAAGTTCTCTTATATGTATATCTTGTATAGAAAAATTAAGAGATGCCAATACTTTTCGTACAATGGTTGTTAATGCTGAAAGACAGTTATTAGATACATTAGATGAAAAACAGACATTTTTTATCAATTTAAGAGGACCATTAATGGAAGTTGATGTGAAAGTAGAAAAAGACACTGAATTAAAAAGAAAGGAGAACAATTTAGATGGAAATTTAAATGATGATGATGATGTCATGTTAGATAAATATGATGATATTTTGCCAGATAATATATCAAATACTGATGGTCCAGTAGAAGGGGAAGCAGAACTTTTAGCAAGGTTCCCACCCGGTACATTAAAACCATTGCCCACCAGAAAAACCATGGAATATACATGTAAACAGTTTGTTAAAGAATTGGAATTATTGAAAGGTAAAAAAATAACTGGTAGCTCAATAAAAAATTTAGTAACACATACAATACCAAATAGAATAAGAAACACCGTGTACATGACGGAAAAGCTAGCCCACATAGCCAATGTATCAACTATTCTGGAACATTCTAATCTAACCGCCTTCAAGACTAGACGACGATCTGGTTTTCCCTGTTTTTACTGCAGACGCATATATGAAAACTTCGAAGTTTTAAAAGATCATCAGTATAATGATAAATGTAAGGCTAATTTAAAAAAAATGTTGGCCAAGTGTGTAATGGACCGACTAGTTGTATATGTTCATATAACAGAAATAAAATGTACTATATGTGATCAAGTTCAAGCCAATTTAAACGAATTGAAGTCACATTTGACAAAAACCCATAAAAAAAAACTCCACCCTGAATATGGAGACAGAATTATACCCTTCAAGCTGACGAAGACGAACGAATATGAGTGTCAAACGTGTGGTTTTAATTTCGAAACTTTTGGTGCAATCGAGCGTCATATGAACGTTCATTATAGGAATTTCGTTTGTGATCAGTGTGGTGCCGGTTACGTGACCCAAAGTCGATTAAAGGTGCATTTAAAATACTCCCACATACAGGGTGTGTTCCCTTGTGATATATGTAACAAAGTGTTCAATACTCAATACAAACACAAGTGTCATGTCGATGCAGTGCATAAAATGGTGAAAAAAAATAAGTGCCCAAAGTGTCCCGAACGGTTTACGGATTACTTTGACCGTCATCAACATATGGTGGAGGCGCATGGAGAACAGCCACTGAGGTACCGCTGCAATGTTTGCATGTCCGTCTTCAAACGGCGTTACGCCCTATCTCTACACATGAAACGACGTCATCTGGAAGTTAAGGAGAAAGAGTGTGATTTGTGTACATACAAGTGTCATACTATAGCCGAGTTGAAGGCTCATATGATCAAACATAATGGTGAAAGAATGTATGAGTGTTGTGTGTGTAAGAAATCGTACGCTAGGAAGAAAACTTTAAAAGAACACATGCGTATACATAATAATGATCGTAGGTTTGTCTGTGTGGTATGCGGTCAGGCATTTGTACAGAATTGTAGCCTAAAAGGTCACATGAAAGCTCATCATGCGGACTATAGTATAGGAATAGGGAGGAGTTAG
- Protein Sequence
- MENNLNSTRFGKCRFCFSKGNHRDIMKEYNWNGVSEIYFDVFQECFNLYLCTNGRSSLICISCIEKLRDANTFRTMVVNAERQLLDTLDEKQTFFINLRGPLMEVDVKVEKDTELKRKENNLDGNLNDDDDVMLDKYDDILPDNISNTDGPVEGEAELLARFPPGTLKPLPTRKTMEYTCKQFVKELELLKGKKITGSSIKNLVTHTIPNRIRNTVYMTEKLAHIANVSTILEHSNLTAFKTRRRSGFPCFYCRRIYENFEVLKDHQYNDKCKANLKKMLAKCVMDRLVVYVHITEIKCTICDQVQANLNELKSHLTKTHKKKLHPEYGDRIIPFKLTKTNEYECQTCGFNFETFGAIERHMNVHYRNFVCDQCGAGYVTQSRLKVHLKYSHIQGVFPCDICNKVFNTQYKHKCHVDAVHKMVKKNKCPKCPERFTDYFDRHQHMVEAHGEQPLRYRCNVCMSVFKRRYALSLHMKRRHLEVKEKECDLCTYKCHTIAELKAHMIKHNGERMYECCVCKKSYARKKTLKEHMRIHNNDRRFVCVVCGQAFVQNCSLKGHMKAHHADYSIGIGRS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01079334;
- 90% Identity
- iTF_00775582;
- 80% Identity
- -