Hmel019323.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heliconius melpomene
Gene Symbol
-
Assembly
None
Location
Hmel217001o:14159942-14162253[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 1.6 1.1e+02 3.6 0.1 2 22 102 122 101 124 0.82
2 9 1.1 76 4.2 0.8 2 20 147 165 146 168 0.92
3 9 5.3e-08 3.7e-06 27.2 0.6 1 23 172 195 172 195 0.97
4 9 0.42 29 5.5 0.5 3 20 201 218 200 220 0.91
5 9 0.0021 0.15 12.7 0.5 2 23 228 250 227 250 0.92
6 9 3.5e-05 0.0025 18.3 0.7 1 20 257 276 257 280 0.90
7 9 0.00073 0.051 14.2 0.4 1 23 285 307 285 307 0.95
8 9 1.7e-05 0.0012 19.3 0.8 1 19 313 331 313 335 0.96
9 9 5.2e-05 0.0036 17.8 2.3 1 23 341 364 341 364 0.97

Sequence Information

Coding Sequence
ATGGAAGATATACAAGAACAAATGTTATTGGTGTCCAGTCGTCGCGCAGTGGGCACTAAGTAGGTGGATTGGTTAGTCGCGGCGCGTCTCAATGCCAAGGTAGTTTTGAAATATACCACGGCGTATCCGTTCAGGATACCAAGTAATTCCATGGTGTGCGTCTACTGTTGCGAGCAATATGATGATCCGAAGATATACAGGCAACATATGAACGAGGAACATTCGGTTTTCAACGTGGAAACGGCTTTCGCACATTCTATGAATAATTACACGGAATATCTGAAAGTGGACTGCTTTGATTTAACTTGTCGCATTTGTAGGGAACCCTTTGAAAGTATAGTTTCTATAGCCGAACACTTAGTCCAAAAGCACAAAAAGAATATGAATTTAAACATAGAAGTGGGAATGCAAATGTTCAAATTAGGCCCCGAGAGATGGGTGTGCGCACTATGCAATCTAAAACTTCCAAGTCTCAGAGAACTGAGTAGGCATACAAGCTGTCACTATCACAAATATACGTGTGAGACGTGCGGTAAATCGTATATAAACAAAGAAAACCTAACCCGTCATATACAATATGGTCATAGTCAATACAAAATCTGCCTAAAATGTAAAGAAGCCTTTCCCAGTTGCGAGGAACGTCGCCAACATGTTCTTTCTTCCGAACGATGTTGGCCACAAAGTTGTAATTTGTGCGGGAAAAGATTTATATCTAGGAAGCTTAGGCTCGACCATTTAATGGAAGCTCACGGGCAAAGACCCAAGAAATACACTTGTCCAGATTGTGGAAAGGTGTTTGATAAGTGGCATCCATACAGAGCACATTTTGTATTATCACATACCAACGATATATACGCATGTTCGTTTTGTGGATTCAAATTTGACACTAAAAGGGCTTTGGCGGAACATAAAGTAATACATACTAAGGAGAAATCGTTTTCTTGTACAGTATGTTCGAAATCATTTGCTAGGAAGAAGAATTTAATCCAACACAGTTGGATTCATAGTGAATATAAAAGATTTGAATGTACTCTCTGCAGTAAACAGTTTAACCAGAGAGTCAGTTGGAAGACTCATATGAAATCGTATCACCCAGAACTGGTTGACTTTTGA
Protein Sequence
MEDIQEQMLLVSSRRAVGTK*VDWLVAARLNAKVVLKYTTAYPFRIPSNSMVCVYCCEQYDDPKIYRQHMNEEHSVFNVETAFAHSMNNYTEYLKVDCFDLTCRICREPFESIVSIAEHLVQKHKKNMNLNIEVGMQMFKLGPERWVCALCNLKLPSLRELSRHTSCHYHKYTCETCGKSYINKENLTRHIQYGHSQYKICLKCKEAFPSCEERRQHVLSSERCWPQSCNLCGKRFISRKLRLDHLMEAHGQRPKKYTCPDCGKVFDKWHPYRAHFVLSHTNDIYACSFCGFKFDTKRALAEHKVIHTKEKSFSCTVCSKSFARKKNLIQHSWIHSEYKRFECTLCSKQFNQRVSWKTHMKSYHPELVDF