Hmel002683.1
Basic Information
- Insect
- Heliconius melpomene
- Gene Symbol
- -
- Assembly
- None
- Location
- Hmel219001o:3257621-3265763[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 6.2e-06 0.00043 20.7 0.9 1 23 260 282 260 282 0.99 2 13 0.036 2.5 8.9 2.9 1 23 290 313 290 313 0.95 3 13 0.69 48 4.8 0.4 1 23 317 340 317 340 0.90 4 13 0.00019 0.013 16.0 3.1 1 23 414 436 414 436 0.99 5 13 0.28 20 6.0 2.0 2 23 445 467 444 467 0.96 6 13 0.37 26 5.7 3.2 1 23 471 493 471 493 0.97 7 13 9e-05 0.0062 17.0 3.0 1 23 498 521 498 521 0.98 8 13 1.4 1e+02 3.8 1.9 3 22 527 546 526 548 0.78 9 13 0.28 19 6.1 0.0 2 20 567 585 566 587 0.92 10 13 0.15 11 6.9 0.2 2 23 630 652 629 652 0.90 11 13 9.3e-07 6.5e-05 23.3 1.4 1 23 661 683 661 683 0.98 12 13 0.00031 0.022 15.3 0.7 1 23 689 711 689 711 0.96 13 13 1.6e-05 0.0011 19.4 4.6 1 23 717 740 717 740 0.98
Sequence Information
- Coding Sequence
- ATGTTTGAATTAAAAGCATGTATAGTATGCTTAAAAAGTGATGTAAAATTTTTTAGTATGAACACGGGTCAATTGAGAAAGGAATTTAATTTAGCGTCAGGCTTAAAGACTAATAGTTATAATGGACTTCCTGAATATTTATGCTATCAATGTGTAGCTCATGTAAAAAATTTCAAAAAATTTAGGGATAAATGCCAACGTACATATTATGCATTACAAGAAGTACTTCATAAAAATAAAGAGATTACAAAGTCTATAATTGAAGAAATAAACTCAAAAGCCCTTAAAATAGAGCCAACTTTGTCATATGTAACTCCAAATAACTTAAGAATTAAGTATGAAAGTGCTAAATTTAAGTGGATACAACAAAACAGAGTAAGTACAAGACATGAAGATGAAATCTCAATATTTCATTATACAACTGCTTCTGATGACTTTGCATTTGAAGTTCCAAGAAAGAAATCTAAGCTATTAACAGAATTAGTACAAGAATGTATAAAAGTAGAAGATAATGCAGAAAATGCACCAACAACCGAAACTGATACTTTAATTGAAAACAAAAATGCAGATCTTGTTACAGAAATTAATGATAGTTTTGATACTGCTTTTGATAATTGTGATGATGTGACTGATATTGATAATAATGAAGTTATTTGTAAAGAGGATGAAGAAGCCGATGGAATGAATTTAGATGAGGAATATGCTACAATTGTACCTATATCTATAGTAGAGGCTAAAGCTGTAGTAGATGTATATAAAATGTTTGCTCACGGCAAGTTCCAGTGCTCAAAATGTGGAAAAGCTTACTATAATGAAAACCGTCTTAGTGCACACATGAGAATGCATGATACACACACAAGTGGAACATTTTTTTGTGATCTATGCAAATATTATTATAGAACGGACTTTTTATTAAAAACTCATATGAATGAAAAACACATGTACAAGTATTTGTGCAAGAAGTGTCCTGAAGTAAGTTTTGACAGGACCTCAGCTAAACAACATTATATATGGAGCCACATGCAAAAAGGTTCTAAGAAAGATGCAAATTGGTATGAATCTCAAAATTCTAGTGCTAATGTAAATAAAAATAGTAAAAAGAACAAATTATTTATACGTCCAATGAGAAATACTAAGAGGCTACCTCAAGACTTTCCAGTGTATTCACCAGTGAGTCAAGAGGAACAATATGCAATTGTCAAAGATAGACAGAAAACTAGAAACTATATTGATTCACCATATAAATGTGAATATTGCTATAAAGGTTTTAGGGAAGAAATGACATATCAAAATCATATGAAAAAACATGATCCTGCACATTCTGGTAAACTGCAATGTGATGCATGCAAAATATTCTGTCCAGATTCAAGGAAAATGTACAAGCATATGAACATGAGTCATTTATTCAAATATTCATGTCAAATGTGCAGTTATGTTTGTTTTAGCAGAGGTCAAGCAAAAATGCATTATAAATGGCATAAAAATGTTACATACTCATGTCCACATTGTAAGAAGGAGTTTACTAAAGCATCAACAAGACTGACCCACATTCGAATCAAACATCCGTCAACTAACATATGTAATTTATGTGGGCACAGCTTCGTCAGCGTGACTGGTTTATACTGTCATAAGAAACTGGCTCATACTGAACAGGAGGTGGCGGCAAGCGCGGGCGTGGCGGACCGCGCGCACCCGCTGTACTGCGCGGAGTGCGACGTGCAGTTCCGCGACGACACCGCGCTCGCCACGCACTACGGCTCCTCCAACAAACACGCTGATACCAACTTATCAATAAAATCACTCAAAAAGGAAGGCACAGGCATACGTCGAGGACGGCCGCGACAAACAGAAAGTGGCATTGTCAATACTGGGGTACCCACGTCTTCTACTTGCGATATTTGTAACAAGTACCTGGCGAACGATTCGCAAGCGCGTCGCCACTACGACGCGGAGCACCCCGGGGCGCACTTCCTCAAGCGGTACATGTGCGACATATGCGGACACACCACTCGGCAATACGCAAACCTAACGGTGCATATGCGCACGCACACGCTGGAGAAGCCATACGCGTGCCCGCACTGCGAGCGACGCTTCAGTATGCCCAGCAACCGAGACAGGCATCTTGTGGTACACACAGGCGAGAAACGCTACCAATGTCAACACTGCCACCGTCGTTTCACTCAAAGTAGCGCTGTTAAACTTCACATACAAACTGTACATTTAAAAATACCTTACGCTCCGTGGGATAAGAAAAATCGTAAACGACGTCGAGACGCTGAAGCCCCCCTTTTGCCTCCCGTCCCCCTTGCCCCCGTGCCTACCACTGCCCCTCTTACGCAAGCTCCTCCTTCTGGTACAGGACATAAGTTGTTACTAGACACGACTCATGGGAATTATCTTAGCGCTTATATTACTTATAATGAGTAG
- Protein Sequence
- MFELKACIVCLKSDVKFFSMNTGQLRKEFNLASGLKTNSYNGLPEYLCYQCVAHVKNFKKFRDKCQRTYYALQEVLHKNKEITKSIIEEINSKALKIEPTLSYVTPNNLRIKYESAKFKWIQQNRVSTRHEDEISIFHYTTASDDFAFEVPRKKSKLLTELVQECIKVEDNAENAPTTETDTLIENKNADLVTEINDSFDTAFDNCDDVTDIDNNEVICKEDEEADGMNLDEEYATIVPISIVEAKAVVDVYKMFAHGKFQCSKCGKAYYNENRLSAHMRMHDTHTSGTFFCDLCKYYYRTDFLLKTHMNEKHMYKYLCKKCPEVSFDRTSAKQHYIWSHMQKGSKKDANWYESQNSSANVNKNSKKNKLFIRPMRNTKRLPQDFPVYSPVSQEEQYAIVKDRQKTRNYIDSPYKCEYCYKGFREEMTYQNHMKKHDPAHSGKLQCDACKIFCPDSRKMYKHMNMSHLFKYSCQMCSYVCFSRGQAKMHYKWHKNVTYSCPHCKKEFTKASTRLTHIRIKHPSTNICNLCGHSFVSVTGLYCHKKLAHTEQEVAASAGVADRAHPLYCAECDVQFRDDTALATHYGSSNKHADTNLSIKSLKKEGTGIRRGRPRQTESGIVNTGVPTSSTCDICNKYLANDSQARRHYDAEHPGAHFLKRYMCDICGHTTRQYANLTVHMRTHTLEKPYACPHCERRFSMPSNRDRHLVVHTGEKRYQCQHCHRRFTQSSAVKLHIQTVHLKIPYAPWDKKNRKRRRDAEAPLLPPVPLAPVPTTAPLTQAPPSGTGHKLLLDTTHGNYLSAYITYNE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00160143;
- 90% Identity
- iTF_00775516;
- 80% Identity
- -