Basic Information

Insect: Heliconius melpomene
Gene Symbol: ZNF526
Assembly: None
Location: Hmel207001o:3252500-3269138[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.88 61 4.5 0.0 1 16 285 300 285 302 0.88

2 18 0.026 1.8 9.3 0.5 2 23 467 488 466 488 0.91

3 18 0.001 0.073 13.7 0.1 1 23 498 521 498 521 0.97

4 18 0.044 3 8.6 4.1 1 21 631 651 631 652 0.93

5 18 0.017 1.2 9.9 1.6 2 23 715 736 714 736 0.95

6 18 0.00014 0.0096 16.4 0.6 2 23 779 802 778 802 0.96

7 18 0.062 4.3 8.1 0.2 1 23 808 830 808 830 0.93

8 18 0.0019 0.13 12.8 3.3 1 23 836 858 836 858 0.98

9 18 0.82 57 4.6 0.1 2 19 869 886 868 888 0.89

10 18 0.063 4.4 8.1 0.1 1 23 967 989 967 989 0.96

11 18 1.8 1.3e+02 3.5 7.2 1 23 996 1018 996 1018 0.95

12 18 0.0012 0.085 13.5 1.8 1 23 1053 1076 1053 1076 0.95

13 18 0.00085 0.059 14.0 1.8 1 23 1083 1106 1083 1106 0.98

14 18 0.05 3.4 8.4 0.1 2 23 1125 1147 1124 1147 0.95

15 18 0.06 4.2 8.1 0.5 3 23 1165 1186 1163 1186 0.95

16 18 0.00039 0.027 15.0 0.7 2 23 1195 1216 1195 1216 0.98

17 18 9.8e-05 0.0068 16.9 0.1 1 23 1222 1244 1222 1244 0.97

18 18 0.00017 0.012 16.1 0.9 2 23 1251 1273 1250 1273 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.88	61	4.5	0.0	1	16	285	300	285	302	0.88
2	18	0.026	1.8	9.3	0.5	2	23	467	488	466	488	0.91
3	18	0.001	0.073	13.7	0.1	1	23	498	521	498	521	0.97
4	18	0.044	3	8.6	4.1	1	21	631	651	631	652	0.93
5	18	0.017	1.2	9.9	1.6	2	23	715	736	714	736	0.95
6	18	0.00014	0.0096	16.4	0.6	2	23	779	802	778	802	0.96
7	18	0.062	4.3	8.1	0.2	1	23	808	830	808	830	0.93
8	18	0.0019	0.13	12.8	3.3	1	23	836	858	836	858	0.98
9	18	0.82	57	4.6	0.1	2	19	869	886	868	888	0.89
10	18	0.063	4.4	8.1	0.1	1	23	967	989	967	989	0.96
11	18	1.8	1.3e+02	3.5	7.2	1	23	996	1018	996	1018	0.95
12	18	0.0012	0.085	13.5	1.8	1	23	1053	1076	1053	1076	0.95
13	18	0.00085	0.059	14.0	1.8	1	23	1083	1106	1083	1106	0.98
14	18	0.05	3.4	8.4	0.1	2	23	1125	1147	1124	1147	0.95
15	18	0.06	4.2	8.1	0.5	3	23	1165	1186	1163	1186	0.95
16	18	0.00039	0.027	15.0	0.7	2	23	1195	1216	1195	1216	0.98
17	18	9.8e-05	0.0068	16.9	0.1	1	23	1222	1244	1222	1244	0.97
18	18	0.00017	0.012	16.1	0.9	2	23	1251	1273	1250	1273	0.95

Sequence Information

Coding Sequence: ATGGCTGAAACACCACCACCTTTAGTACTTTGCATGGATGATATAAACGGAAAGGAAGTGGAAGTGAAGATAGAACAGAATGATACCTTCCAAACTTTTATTAATAATTCCAAAACTCTTCTCGGATATGAACTCGATCTTAATTCAATAACAGGGAATCAACAAGTGTCTCTCGATGACAATGCCTATACGTTCCTTTTAAGTACTGAGAAAAATCTCACCGATTCTACCTTAGACCCAACAAATTTCGAACTAGGTGCAAATCAGGCTGGTACTGACGATTTAGTCTACATCTTAGACGATGGCACTCAAATTCGCGCCTCTCAAATACATTTTGATAATGACGACCCCCTTACTGATTTAACATTAGAAAAATTACCTTTTATTAAACACACAGACGATGTAGATGAATCAGTTGATGATAATACAGAGACTGGTGAAATTAAAAATATAAATATTACCAGTCCAGTATCGAATAAGAACAGTCCCAAGTATAGCTTCGCGAACACTCTACCGTTCAAATTGGTTTCTAATAACGCAGCTAGTTTCGAAGCTCAATTTACGAAATATCTCGAAGAAAAATCTAAAACGTATGCAACTTTGCAATTGGCAAATAAAAATAAATCGCCCAAAACGTTGATTAGTGAAAATTATAAAAATAGTGATATAGCAAATCGTAATGTTTATACACGTGAGGATATTCTCGATATGTTCAAAAATTCTCCAGTAACATTCCTTCCGTATGATAATCAAAATTGTGATAAGCGTAGGCATGTTAGAAAAACTGACCCATCAAGACTTGGTAGGAATTGGAGCTCCAAACCTTTAATAGATATAGAGGCTAAAGACAAACATATTTGCTATATATGTGGTAAAATGGTGGATAACAAGGAAAAATTATATATTTTCGACAAAGAAGATCAAATGTTACACAGAAGTGAACAAAAGAAATATACCCAACTTAAAGTTATTTGTGAAATCTGTTTAACCGAAAATTTTGTGGCCAGTCGACTTAAAGGCTCGGAAGAAGCATTAAAAAATGATGAATATTTGGTCATTAAGAATAATCAACAGTTTATTTTTAAGAAAACAAGTTTGATTACTTTCAAACATACTTATAAATCTAATATTTTAAATGATAATGATATTAAAGAGAGCTCAGAGTTTGTTAACGTAGAAATCGGTCCCGACGGTGAAATTATAACTAAACCAGTCTGCAATATTAAGGCTGATGATTTAATAATAATAAAGGATGAGAAAAAAGGTAGTTCCAGTGACGTAGAGATTATAGAACCTGAAGCGGAACCGGAAATTGATTTAGACAATATAGATGAAGACGAAAACGTTAAAGAGTTTTTGGGGAAGTACCAAAATGATAGTAGTGATGTGAAAGAGTTAAAATGTAGATTTTGTAACAAAGACTTTAAAGATACTTCCGAAGTAATAAACCACGGTGAAGAACACAAGCACGATGCGGAGGGAGATGTAGTGTTCCCTTGTCCTTTGTGTGATTATGGATATTCTAACTTTAAATGGCTAAAAGGACACCTCAAAGTGGCCCACGACAATACTAAAACGGAAATTGATGAAGATGTAACTAAAGAAAATGATGAAAAATCACCGTCTCCCAAAAGTTCTCCTGTTGCGAAGAGAACGAGAAGTTCATTGAAGAAGAGTGATCTTGAAAATGAACATGGTACAAAAGAAAATCAAAATAATGAAGAAACTAATGAAAATGCATCGAACGAACTGACTTTTACCACTGAGGTCAAACAAGAGTGCTTGGACAGCGACGATTCTATATGGATAGTCCAAACTGGGGACTATGATGACGAGTTGCAGAAATTATTGAAGGTAAATGAACCTACCAACGTTAATGATCTAAAGAAGCACAAATGTTTTAAATGCAGCAAAATATTTCCCAATTCGGAAACCTTATCCGTTCACAAGTGTAAGAAAAGAGGCAGAAAACGTAAAGTTATTTCTAAAGACGAAGCTGTTATATTAGTGCCGTCTGAAGAGGACTTTATAAGGAGAGCTCAAGGAAGACCTCGTCCAACAGAAGAGTCGTGTGATAATGATCTTTTAGTGGAGAGAACACGCAAAAGAAAAAGTCGCGCTTCAAGCGACGCTCAAATAGTGACATGCGATAATTGTAACGAATCTTTCACTTCGAAAGTTAGATTGAAATTTCATATGCAATTCCACGATCCAAGTAATCTATTAATATCAGACGGTGAATACAAATGTATCGAGTGTGAGAATGCTAAGTTCTTCACGGAAACGGAGCTGTTCGATCACGTGCATTTCCAGCATGATAAGCAAAAGCGATGGCAGTGCCCCGTCAAAGGGTGTGGAAAAACATTCTTTTTGAGGGCAACACTGACAAAACACAGTCGCACACACACAGACACGCGGCGTTACGTGTGTGTGACCTGCGGTAAAAGATTTCTGGATAAACAGACGTTAGACGAACATGGGGTTACTCATTTACAGATAAAACCATTCCAATGTCACATATGCTTAAAACAACTGACCCGTCGCTCCCGTCTCCGCATGCATTTGCGAGCTCACGAGGAAGAACTGTCCCCAGCTTTGGTTCTAGTTTGTGGTATATGTTTTAGAGCTTTTAGAGATCATAATGATGCACAGGAGCATTCCGTTAAATCAACGGAATGTATAACAGAGTTTACAAAAGATTTGAAAGAAGATGCGGAAGCGAGTGAACAACTGTCGCCCACTAGTGGTATTGTCAGACACACTGTTAGGATTGTGGAATGCCCGCGTCTATCCCAAGGAATAGAGAGACAAGTTAACAACACGATGAGTGAACAATTGCTGTCTAATTTAGACGAAGCGGCTAAAAATATTATACGAGTGGTTAACATAGAAAAGGCGTTCCGTTGTGAATATTGTGAAGATGTGTTTTATTTGGAAGATGCTCTAAATAACCATAGAGTGATACACAAAGGAATAAAAAATCCATTCACATGTCATATTTGCAAAGTCAGTTTTGCTACTTATTCGAGGTGCACTACGCACAAAACAACCCACGGTTTTTATAAACGTAACACTAATGAGAGTAGAAATGAATCTACTTCCGGTCCGGCGAGCGCGGGGATCTTAGGTTACGGGGGATTTCCTGTTGTGAAGCACTTCCTATGCGAGGACTGCGGCCGGTCTTATTTACATTGGACGTACCTACAAGTACATAGACGAATGAAACATGCAAATGAAAATTACATATTTAAATGTAATCAGTGTGATTTGACCTTTCCTAATAGTTGGAGTGTAACATACCATAGAAAGAAAACTCATAACAACGATGAAAATGGTGGTTTTACTAAAATCGTACGCGATAATTATCGTATTCCATGTCGCGACTGTGATGCCATTTTGCCAAACAAAAATGAACTCTACAAACACAGAAAGAACGCACACAGTGACGAATCAATGCAAATAGTGAGACCAGGTAATGGTCGAAATACAATTTGTAATCAATGTGGAAATAATCTACACAACGTGTACGCGTTACAGAAACATATTAGAGAAATACACGCCACAGACAATAAACAGTCCAACACATGTTCGACATGTTCGCGATCGTTCCGTTCGCCGTCCGTTCTGGACGAACATGTCCGCACGCACACCGGCGAGAGGCCGTTCCCGTGTGACGTGTGCGGTGTTGCTTTTAGACGGTCAACAGCCATGAAAAACCATAGATTAATTCACACAGGCGTAAGACCGTGGGTTTGTATGAGGTGCCCAAAAAGGTTCCGCATAAAGTCTGATCTGAGGACTCATATACGATTGAAACATCCAACGCATATGGCGGTCATAGAGATCGAAGGCACTAATTGTACCCAGGAAATGATCTATCAACATTTAGCTTCAAACAATATTACACGAGATAAAGTTATTGAAGTTTCAACAGTCTCTTTTGCTAAGAATTCTACCAACATAGTACCAAACTCAATTCGGGCGTTGTCCCTAATGAATGATGTCCCTAAAAATTGTATAGTGGTACCAAAACCAACGGAACTAAATGACATATGTCAAACATATCGACGTGGCAGAGGTATAGGAAAAACGATACAACTAAATAAAACTAACGATAATTCTAATGACTACCAACATAATAATAATCTACCTGAAATGCAAGTAGAAAAAAGTAATTTATTACAAAACTTATCAAATATCAATGTGGAATTATTACTTCAAGATGGAAATTTAGTGAACGGAAATGAAATGGTACAATTACATATAAATGATGAAATATTGGAAGAGTAA
Protein Sequence: MAETPPPLVLCMDDINGKEVEVKIEQNDTFQTFINNSKTLLGYELDLNSITGNQQVSLDDNAYTFLLSTEKNLTDSTLDPTNFELGANQAGTDDLVYILDDGTQIRASQIHFDNDDPLTDLTLEKLPFIKHTDDVDESVDDNTETGEIKNINITSPVSNKNSPKYSFANTLPFKLVSNNAASFEAQFTKYLEEKSKTYATLQLANKNKSPKTLISENYKNSDIANRNVYTREDILDMFKNSPVTFLPYDNQNCDKRRHVRKTDPSRLGRNWSSKPLIDIEAKDKHICYICGKMVDNKEKLYIFDKEDQMLHRSEQKKYTQLKVICEICLTENFVASRLKGSEEALKNDEYLVIKNNQQFIFKKTSLITFKHTYKSNILNDNDIKESSEFVNVEIGPDGEIITKPVCNIKADDLIIIKDEKKGSSSDVEIIEPEAEPEIDLDNIDEDENVKEFLGKYQNDSSDVKELKCRFCNKDFKDTSEVINHGEEHKHDAEGDVVFPCPLCDYGYSNFKWLKGHLKVAHDNTKTEIDEDVTKENDEKSPSPKSSPVAKRTRSSLKKSDLENEHGTKENQNNEETNENASNELTFTTEVKQECLDSDDSIWIVQTGDYDDELQKLLKVNEPTNVNDLKKHKCFKCSKIFPNSETLSVHKCKKRGRKRKVISKDEAVILVPSEEDFIRRAQGRPRPTEESCDNDLLVERTRKRKSRASSDAQIVTCDNCNESFTSKVRLKFHMQFHDPSNLLISDGEYKCIECENAKFFTETELFDHVHFQHDKQKRWQCPVKGCGKTFFLRATLTKHSRTHTDTRRYVCVTCGKRFLDKQTLDEHGVTHLQIKPFQCHICLKQLTRRSRLRMHLRAHEEELSPALVLVCGICFRAFRDHNDAQEHSVKSTECITEFTKDLKEDAEASEQLSPTSGIVRHTVRIVECPRLSQGIERQVNNTMSEQLLSNLDEAAKNIIRVVNIEKAFRCEYCEDVFYLEDALNNHRVIHKGIKNPFTCHICKVSFATYSRCTTHKTTHGFYKRNTNESRNESTSGPASAGILGYGGFPVVKHFLCEDCGRSYLHWTYLQVHRRMKHANENYIFKCNQCDLTFPNSWSVTYHRKKTHNNDENGGFTKIVRDNYRIPCRDCDAILPNKNELYKHRKNAHSDESMQIVRPGNGRNTICNQCGNNLHNVYALQKHIREIHATDNKQSNTCSTCSRSFRSPSVLDEHVRTHTGERPFPCDVCGVAFRRSTAMKNHRLIHTGVRPWVCMRCPKRFRIKSDLRTHIRLKHPTHMAVIEIEGTNCTQEMIYQHLASNNITRDKVIEVSTVSFAKNSTNIVPNSIRALSLMNDVPKNCIVVPKPTELNDICQTYRRGRGIGKTIQLNKTNDNSNDYQHNNNLPEMQVEKSNLLQNLSNINVELLLQDGNLVNGNEMVQLHINDEILEE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00621441; iTF_00782881; iTF_00774794; iTF_01182103; iTF_00457436;
90% Identity: iTF_00621441;
80% Identity: -