Hmel018235.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heliconius melpomene
Gene Symbol
-
Assembly
None
Location
Hmel217001o:14258323-14267245[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 45 0.23 16 6.3 0.1 3 23 86 107 84 107 0.96
2 45 1.7 1.2e+02 3.6 0.3 2 23 132 154 131 154 0.93
3 45 0.006 0.42 11.3 1.4 2 23 177 198 176 198 0.97
4 45 0.00083 0.058 14.0 0.0 1 23 202 224 202 224 0.98
5 45 0.0046 0.32 11.6 1.5 1 23 229 252 229 252 0.97
6 45 4.6 3.2e+02 2.2 5.2 2 23 260 282 260 282 0.95
7 45 7.9e-05 0.0055 17.2 1.7 2 23 290 312 289 312 0.96
8 45 0.1 7.3 7.4 8.2 1 23 318 340 318 340 0.98
9 45 3.1e-05 0.0021 18.5 5.8 1 23 346 368 346 368 0.98
10 45 0.0039 0.27 11.9 0.9 1 23 460 483 460 483 0.92
11 45 0.21 15 6.4 0.2 2 23 510 532 509 532 0.96
12 45 0.34 24 5.8 3.2 2 23 555 576 554 576 0.97
13 45 0.12 8.5 7.2 2.4 1 21 580 600 580 602 0.94
14 45 0.0057 0.4 11.4 2.0 1 23 607 630 607 630 0.98
15 45 0.14 9.5 7.0 0.4 2 23 638 660 638 660 0.97
16 45 0.00059 0.041 14.5 6.1 3 23 669 689 668 690 0.93
17 45 0.005 0.35 11.5 1.0 1 23 696 718 696 718 0.98
18 45 8e-05 0.0056 17.2 4.3 1 23 724 746 724 746 0.99
19 45 6e-05 0.0042 17.6 4.8 1 23 752 775 752 775 0.98
20 45 0.035 2.4 8.9 1.0 1 23 885 908 885 908 0.95
21 45 0.042 2.9 8.6 2.8 2 23 980 1001 979 1001 0.97
22 45 0.32 22 5.9 0.9 1 17 1005 1021 1005 1027 0.86
23 45 0.31 22 5.9 0.7 1 23 1032 1055 1032 1055 0.95
24 45 2.1 1.5e+02 3.3 6.5 1 23 1062 1085 1062 1085 0.95
25 45 0.0066 0.46 11.2 1.0 2 23 1093 1115 1092 1115 0.96
26 45 0.0016 0.11 13.1 2.4 1 23 1121 1143 1121 1143 0.96
27 45 0.00032 0.022 15.3 2.0 1 23 1149 1172 1149 1172 0.98
28 45 0.36 25 5.7 0.2 3 23 1240 1261 1238 1261 0.93
29 45 1.8 1.3e+02 3.5 0.4 2 23 1287 1309 1286 1309 0.94
30 45 0.17 12 6.7 0.4 2 23 1332 1353 1331 1353 0.96
31 45 0.0006 0.042 14.4 0.7 3 23 1359 1379 1357 1379 0.96
32 45 5e-06 0.00035 21.0 0.9 1 23 1384 1407 1384 1407 0.98
33 45 3.7 2.6e+02 2.5 0.3 2 23 1415 1437 1414 1437 0.83
34 45 0.00028 0.02 15.5 0.6 2 23 1445 1467 1444 1467 0.96
35 45 1.5e-05 0.0011 19.4 1.6 1 23 1473 1495 1473 1495 0.98
36 45 5.1e-05 0.0035 17.8 4.1 1 23 1501 1523 1501 1523 0.99
37 45 0.00041 0.029 14.9 2.7 1 23 1529 1552 1529 1552 0.97
38 45 0.0079 0.55 10.9 0.9 1 23 1616 1639 1616 1639 0.94
39 45 3.4 2.4e+02 2.6 0.1 2 23 1666 1688 1665 1688 0.93
40 45 0.076 5.3 7.8 0.2 4 23 1713 1732 1710 1732 0.92
41 45 0.46 32 5.3 0.0 1 21 1736 1756 1736 1758 0.88
42 45 0.29 20 6.0 1.7 1 19 1763 1781 1763 1786 0.83
43 45 0.0018 0.13 12.9 0.9 2 23 1824 1846 1823 1846 0.95
44 45 0.0046 0.32 11.6 3.9 1 23 1852 1874 1852 1874 0.97
45 45 0.0026 0.18 12.4 2.0 1 23 1880 1903 1880 1903 0.98

Sequence Information

Coding Sequence
ATGACTGAGGGCCAGATAATCGAGTTTCTACCGTGTCAAAAGGGCATAATCAACGAATCTGAAGAAAAGCATGAAGAGACAGCAAAAAAAGTCAAGGAAATCAAAAGTAACACGCTAAAAAAGAGTCGCACTCCTAAAAAGAAAGTCGACGAAAAATGCATGCAAGAAGTAGAAAAGCACCGAAAAAATTTTGTAGAAGTAATAACATATTCTAATGCAACGCCTATTCGTTTTAAAGGCGATATAGGTTACGGATGTTACTTTTGTTCAGAACAGTACCCGGACGCTGCTGATCTCAAACTCCATACGATAACAAAACATGATAACGACAGCGTTATACAAGTTGCCAAAGATATGCGTATTTATACACTTAAATTAGATGTAACGGCTTTGCAATGTTGCATATGTCAATTAGATATATCAACGATAGAGGAACTAATGAATCATCTTGTGAAAGAGCACCAACGTGTAATTTACGTGGACATCAAAAATCATATGGTTCCATTTAAATTTGAAAATGAGGATTTGAAATGTGCCATATGTTTAACGAAATTTATGAAATTCAGAAATTTAACTGAACACATGAACACACATTATAGAAATTACGTGTGTGACGTGTGCGGCGCTGGCTTCGTCAACCGTGACATTCTGCGCAGTCATCTGAGAATTCATAAAATAGGCGATTTCACTTGCGATTTCTGCACAAAAACGTTTAACACTCTAGTGAAGAAACAGTCCCATATAAACATAGTACATAAGAAAATGTATATGACAAGAAAGTGCGGATATTGTAACGAACATTTCGATGATTATCACAAGAAAAACGACCACTTGACGAAATTTCATGGCGTGGATTTAGTTATCTTAAAATGTGATCTTTGCGATAAAACTTTTATCAACCAAAATCGGTTTAATCGTCATGTTAGGAAAGATCATCTCATGGAAAGAAATCATGAATGTGGACTTTGTGATATGAAATTCTTTTGTTGTGAAAATTTAAAAAAACATATGCGGACGCACACTGGACAGAAGGACTATCACTGCAGTATATGCACCAAGTCTTTTGCACGCAAGTTTTCTTTAAAAAAACACTCGCGAACACATTCTAAGAATCTGGAGGAATCTGACACGGATGCTGACCGTGATCCTACCGAAACTGTATATTTTGAAGAATTTAAGAATGTTCGCAAATTAACTAGAAAAAGAAAAATAACAGTGGACAGTGAAAGCACTATGAAAAAGAAGGCTAAAGTAACGATAGGATCTAAAAAAATTAAATTAAAACCAATTAAAGAATTATCCAAACATCATCACAATATAAAAGAGATACTCCAGTGTTCCAACACAACCCCTATACACGGCAAATGCGATCTGGGCTACTTGTGCTGCTATTGCACTGAACAGTTTCCAGATCCAGCCGATTTGAAAAAACACACAATACAACTACACAGAAATGGAATTAAACCGACTTTCTTTCAAAAGAGAGATTTACAGAAATTTTACGTCAAAGTTGACATCACTGGATTGCATTGTAACATTTGCGCGAAAGATATAGAGGATTTGGACAAGTTGATCGATCACCTAAAAACTGTGCATGATAGGAAAATATATACAGATATAAAAAACCATATGGTACCATTTAAATTTGGTAGTGAGGAACTGAAATGTTTTATATGTTCAAACGTATATACTAAATTCAAAATGCTTCTGGAGCACATGCATAAACACTGTAGAAATTTTATATGTGAACTGTGTGGTGTCGGATTTTTTAATCGTAGATCGTACATAAATCACCAGAAGTGTCACGTGGTGGGAGAATACAAATGCGACCGGTGCGACAAGGTCTTCGATAATGTTCAAAAAAGAAATCAACACTTTAGGACCGTTCATGTGCACGAGTACAAACTAAATAGATGCGGATACTGCAATGAGAAGTTTGCTGGGTACCGAACTAAAGCTGAACATTTGAGAACTGTTCACGGCGCTGGATCTGAAACGGCCGAGTGCCGAGCTTGTGAAAAGAGCTTTTGTAATAAAGATTCTTTAAGAAAACATATCAAAAGACACCATTTGATGGAGAATCAATACAGCTGTACATTATGTGAAATGAAATTCTTTGCTAAGAGAAATCTATCAGAACATATGGTGACACATACGAAAATCCGTTCGTTTCAATGCAACGTATGCTTTAAGAAGTATGGGCGAAAGCACACATTACGAGAACACATGCGAATACACAACAACGACAAACGCTACAAGTGCGAACACTGCGGGATGGCTTTCGTGCAAAAGTGCAGTTGGCGACGACATATGCAATCGAAACACGACGAGCAGATGTCAAATACCAAGAAGTACATAATATGTCCCAAAACACGAGAAGACGTCAAGAGAAGACTACCAAATTCATTTAAACTTATTATTCCTTTGACTGATATCAGCTTCTTTGTAGTTATTATGATTCATTGTAAATCTCACAAAACATCCAAAGCATCATTGAACACTTCTCAAGAGGATGAAATTGTTGCTATAAATAAAGAAGACGTTGTTCCTAAAGCTAGGCAAGGAGAACATTTGGAAAAACATAGAAACAATATAAGGGAAGTTATTCTTTCGTCGAACGCTACGCCGATTAGGTGTCGAGGTGGCATTGGTTATGCGTGTTGTTTTTGTTCCAGTCAGTTTCCTGATCCTGCAGACTTAAAGAAACATACGATAAAAGATCATGACGATAAGACGAAAGCAATATTTATGAAAGGGCGGGATATGTACGGATACTTAGTTAAATTAGATATTACAGGATTAGAATGTAATCTATGTAGATCAAGGCTGGAAACTCTAGAGAAAATTTTGGAGCACTTAAAAGACGCTCATAGTAAGAATATCAGCACAGAGATACCTAACCATATTTTGCCTTTCAAATTTGACAATGAATATTTAAGGTGCTTCATATGTCAGAATATTTTCAACAAATTTAAAGCTCTCCAAGAACACATGCATACACATTACCGAAATTATATTTGCAAAATCTGCGACGCTGGATTTGTTAACCGCCATCTTCTATTATGTCACAATGAGGGCCACAAAACTGGTACCTTTGCTTGTGAACAATGCAATCTAGTTTTTGACACTGTTAGAAAGAAGAAATTGCATGAAAGAAAAATCCATAATGGCTTAAACATGCCCCACAAATGTGGATACTGCAGTGAGAGGTTTAGGGAGAATTGTCACAAAAATGAACACTTAGCGAAAGTACATGGTGTCGTTGGACCAACAATTAAATGCCAAGCTTGCGACAAGACGTTTACATTGCAGCAGACTTGGTTACTACACATGAAAAAGTATCACTTGCTGCAGAAGAAACATAACTGCACGACATGCGATATGGCCTTCTTTTCTAAGCGGGAGTTAACAGACCACATGGTCAAACACACGGGAACGAGAGAGTTCAAATGTGAAGTTTGCAAGAAATCGTACGGCAGATTAAAAACATTAAAAGAACACGTGAAGAGGCAACACCCAGAAGATTGTTTCTATAAATGTATACGAACCATTAAAATCGAAAGGCGTTTATCAACACCTCGAGTCGAGTTGAAGATCATTCGGGGCACCAGGCAGCCTAAACTGTCGGATGCCAGGAAAAACCAACAAAATCTTATGACCATTTTGCTTTGTTCCAATGCCAATCCTATCAGATCGAAGGATAGTCTTGGATACGGCTGTGCGTTTTGTCTCGAACAGTTTCAGAATCCGACCGACCTTAAGAAACATTTTTTAGTAGAACATAACAACGACAGATTAATTCAGTACATGACGTCCAGATTGTTTGAACATGTCGTTAAATTAGACATTACCTACTTAAGTTGTTCCCTTTGCAGCAATGTTATAGCCAAATTGGAGGACTTGATGCATCACTTGAAGAATGAGCATAAAAAAGAAATACACACAGACATAAACAACACTATAGTACCATTTAAATTCGACACGCCGGAACTAAGATGCGCAATTTGTTCCACGGAATATCTAAACTTCAAACTGTTACAGGAACATATGAACACTCATTTTGGATACCATTTATGCCCACTGTGCAGCCGGGGCTTTGTTACTGAGCGCCTTTTAGCCACTCACATCAGGAGACATGACAATGGTGTATACAAATGTCAAGAGTGCGATAAAGTGTTTGGCAATAACGAGAGGTTAAAGGAACATCAGAGACGGATTCATTTAGGGTTCAACAAACGCAACAAATGTATGATATGTGATGAACGTTTCATGGATTACTGGAGGAAGGTCGATCATATGGTTAAAGTGCATGGAGCACCACCAGTAGTCATAAAATGCCAAGCTTGCGATCGCACTTTTATCAACCAGAGAGCTCTGGCGCGGCACACTAAAAAAGACCATCTTATGGAAAAAAAGCACCAATGTGAAGAATGTGATATGAAATTCTTCAGCGCTAGCGGACTAAAGCGTCATATGGCGAAGCATACAGGACTGCGTGAGTTCAGATGTGATATTTGCTTCAAATGCTATGGCAGAAAGACTACGTTAAGGGAACATATGCGTATACATGCAGACGACCGCAGGTTTGCCTGTAGTAGATGTGGTCAGGCTTTCGTACAAAAGTGCAGTTGGAAGAGTCACATGAGATCCAAACATGGTGACCAGAAACTAACAATTCCAACAAATGTGGAAAGAAAAGACCGAAAACGCAAAACCATAGGAATAACTGTCGAACAGAAACTAAATATGGTGATTGTGTCAGAGGTGGAAAAACATCAAAATAATATAAAAGAAATTTTATTGAATACGAATGCTACGCCCATTCGTTGTAAGGGAGGCATCGGTTATGCGTGTTGTTTTTGCTCTGAGCAGTTTCCTGATCCAAAAGATTTAAAAGCACACACCCAAGAATCTCACAACGCTGAAGAAAAATCTACCTTTATGAAAGGCAAAGACATGCACGGCTATTTCGTTAAATTAGATATCACAGACGTTAAATGCCTAATTTGTGGAGAAACCATGGAGAGTGTAGACAAAGTAGTTAACCATCTGCAAATGAATCACGATAAGAAACTTTATACGGACATTAAGGATCATATACTGCCCTTTAAATTTGGCAATGGACCACTCAACTGTATTATATGTTCGAACGTATTTAACTCTTTCAAAGCTCTCCAAGAACACATGAATGTTCATTATAGTAACTATTCATGTCTAGTCTGCGGTGCAGGTTTCGTTAATAAGAACATCCTTCTAAGACACGGAGATGCCCACAAAATAGGAACGTTTACCTGCGAAATATGTTCCAGAACATTCGATACGGAGCGAAAAAAGCGATTGCATGATCGATCAAGACACGCCGGAATAAAATTACCTCATAAATGTGGTTATTGCATGGAAAGATTTAAAGAAGTTTGGAAGAAACAAGAGCATTTGGTTAAAGTCCATGGAGTGAAGAGTCCAGGGATCAAGTGCCAAGCGTGTGACAAGAGTTTCGAAAGCAAACATTCTTGGAGGCTGCATATAGCAAGAGTGCATCTCTCGCAAAGACCACACAAGTGTCAGCATTGTGACATGGAGTTTTATGCTAAGAAGGAGTTAGAGAGCCACATGGTGAAACATACTGGTTCTAGGGAATTTAAATGTGAATCATGTTTCAAGACATACGGACGATTGAAGACCTTAAAGGAACATGTCCGAAAAGTACACGCTTGA
Protein Sequence
MTEGQIIEFLPCQKGIINESEEKHEETAKKVKEIKSNTLKKSRTPKKKVDEKCMQEVEKHRKNFVEVITYSNATPIRFKGDIGYGCYFCSEQYPDAADLKLHTITKHDNDSVIQVAKDMRIYTLKLDVTALQCCICQLDISTIEELMNHLVKEHQRVIYVDIKNHMVPFKFENEDLKCAICLTKFMKFRNLTEHMNTHYRNYVCDVCGAGFVNRDILRSHLRIHKIGDFTCDFCTKTFNTLVKKQSHINIVHKKMYMTRKCGYCNEHFDDYHKKNDHLTKFHGVDLVILKCDLCDKTFINQNRFNRHVRKDHLMERNHECGLCDMKFFCCENLKKHMRTHTGQKDYHCSICTKSFARKFSLKKHSRTHSKNLEESDTDADRDPTETVYFEEFKNVRKLTRKRKITVDSESTMKKKAKVTIGSKKIKLKPIKELSKHHHNIKEILQCSNTTPIHGKCDLGYLCCYCTEQFPDPADLKKHTIQLHRNGIKPTFFQKRDLQKFYVKVDITGLHCNICAKDIEDLDKLIDHLKTVHDRKIYTDIKNHMVPFKFGSEELKCFICSNVYTKFKMLLEHMHKHCRNFICELCGVGFFNRRSYINHQKCHVVGEYKCDRCDKVFDNVQKRNQHFRTVHVHEYKLNRCGYCNEKFAGYRTKAEHLRTVHGAGSETAECRACEKSFCNKDSLRKHIKRHHLMENQYSCTLCEMKFFAKRNLSEHMVTHTKIRSFQCNVCFKKYGRKHTLREHMRIHNNDKRYKCEHCGMAFVQKCSWRRHMQSKHDEQMSNTKKYIICPKTREDVKRRLPNSFKLIIPLTDISFFVVIMIHCKSHKTSKASLNTSQEDEIVAINKEDVVPKARQGEHLEKHRNNIREVILSSNATPIRCRGGIGYACCFCSSQFPDPADLKKHTIKDHDDKTKAIFMKGRDMYGYLVKLDITGLECNLCRSRLETLEKILEHLKDAHSKNISTEIPNHILPFKFDNEYLRCFICQNIFNKFKALQEHMHTHYRNYICKICDAGFVNRHLLLCHNEGHKTGTFACEQCNLVFDTVRKKKLHERKIHNGLNMPHKCGYCSERFRENCHKNEHLAKVHGVVGPTIKCQACDKTFTLQQTWLLHMKKYHLLQKKHNCTTCDMAFFSKRELTDHMVKHTGTREFKCEVCKKSYGRLKTLKEHVKRQHPEDCFYKCIRTIKIERRLSTPRVELKIIRGTRQPKLSDARKNQQNLMTILLCSNANPIRSKDSLGYGCAFCLEQFQNPTDLKKHFLVEHNNDRLIQYMTSRLFEHVVKLDITYLSCSLCSNVIAKLEDLMHHLKNEHKKEIHTDINNTIVPFKFDTPELRCAICSTEYLNFKLLQEHMNTHFGYHLCPLCSRGFVTERLLATHIRRHDNGVYKCQECDKVFGNNERLKEHQRRIHLGFNKRNKCMICDERFMDYWRKVDHMVKVHGAPPVVIKCQACDRTFINQRALARHTKKDHLMEKKHQCEECDMKFFSASGLKRHMAKHTGLREFRCDICFKCYGRKTTLREHMRIHADDRRFACSRCGQAFVQKCSWKSHMRSKHGDQKLTIPTNVERKDRKRKTIGITVEQKLNMVIVSEVEKHQNNIKEILLNTNATPIRCKGGIGYACCFCSEQFPDPKDLKAHTQESHNAEEKSTFMKGKDMHGYFVKLDITDVKCLICGETMESVDKVVNHLQMNHDKKLYTDIKDHILPFKFGNGPLNCIICSNVFNSFKALQEHMNVHYSNYSCLVCGAGFVNKNILLRHGDAHKIGTFTCEICSRTFDTERKKRLHDRSRHAGIKLPHKCGYCMERFKEVWKKQEHLVKVHGVKSPGIKCQACDKSFESKHSWRLHIARVHLSQRPHKCQHCDMEFYAKKELESHMVKHTGSREFKCESCFKTYGRLKTLKEHVRKVHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-