Basic Information

Insect: Heliconius himera
Gene Symbol: ttk
Assembly: GCA_013421065.1
Location: JAATLT010015874.1:44604-58314[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.17 13 6.6 0.0 2 23 488 510 488 510 0.90

2 6 0.00026 0.02 15.5 0.9 1 23 521 544 521 544 0.94

3 6 0.00029 0.022 15.4 2.7 1 23 554 576 554 576 0.97

4 6 3.3e-06 0.00025 21.5 2.1 1 23 729 751 729 751 0.97

5 6 4.1e-06 0.00031 21.2 0.2 1 23 757 779 757 779 0.98

6 6 2.5e-05 0.0019 18.7 3.3 1 23 785 807 785 807 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.17	13	6.6	0.0	2	23	488	510	488	510	0.90
2	6	0.00026	0.02	15.5	0.9	1	23	521	544	521	544	0.94
3	6	0.00029	0.022	15.4	2.7	1	23	554	576	554	576	0.97
4	6	3.3e-06	0.00025	21.5	2.1	1	23	729	751	729	751	0.97
5	6	4.1e-06	0.00031	21.2	0.2	1	23	757	779	757	779	0.98
6	6	2.5e-05	0.0019	18.7	3.3	1	23	785	807	785	807	0.98

Sequence Information

Coding Sequence: ATGGAGTGCGAGGCTCGAATTTGTTACGTTACGTTCTTTCCGCTTGAAAAATGTTATGCGTGGAACAATCATCAGAGCAACTTGCTCGGCGTTTTCAGCCAACTGCTACACGACGAGAGCTTGGTGGACGTCACGCTCGCCTGTTCCGAAGGTGCCTCCATACGGGCTCATAAGGTAGTACTATCTGCGTGCTCATCCTACTTCCGCTCGCTTTTCGTGGATCACCCTTCGCGTCAtccaattgtaattttaaaggaCGTGGGCTTAGAGGAGCTCCGGACACTCGTCGACTTCATGTACAAGGGCGAAGTGAACGTCCAGTACTGCCAACTGCCCGCTCTCCTTAAAACGGCTGAGAGCCTTCAggttaaagGATTAGCGGAAATGACTACGCTTAGTGCAGCCGGCATCGACACCCGAAACGTCCCAGAACCGATGGAAGAGTGCCAGCAGCAAGATATTAGGGAACCAATAGATTCACATGAAAGGCTAGACGAGCGGGAAGGTCGCGACAAAGAAGAACGCAGAGACGTAAAAGACAGCCGTGAATTCCGTGACAGGGAATGCAAAGATATGAGAGAAAGCCATAGAGACTCTCGTGAGGCAAGAGATGTGCGAGAACATAGGGAAAGAGATAGAGAACGTGATAGAGAAAGAGAGCGGGAAGTCGCGCGGGATAGAGATGCTCGCGACCAACGTGAACACCGAGACTCCAGAGACCATAGAGAACTACGTGACATAAAAGATAATAGAGAACCTCGTGATCTACGGGAAATAAGAGATTCGAGGGATTTACGTGACAATCGAGATCCAAGAGAGGTACCAGAAGCATCACCTCCAAGAATATCTCCTTTACTATCTGTCCGACGGTTTAGGCCCGAAACGTCAATTGAAACACCGACATTAACGCATCCGCCTATACCTAAAGATGAACCACCTGACGAACCTATGCGGCCCTCATCTCCCGAAGATGATTCAGTATCTATTAGGTCAAATGGTGCAAACGACAATATGGgtATAAACATGACCATAAACAGCCATGGACTGGGACCAAGGTACTCTCCCGTTGAACAAAGGCTGAGTGTTTTAAATACACTTTCTCATCCCGGATTGCCTCATCCCCTTTCCCTATCGAGTCCGAGAAATGAACCAATTGCCGGACCCTCAGGGCTGCCTCCAGTTCAGCAAGTGCCCTTGtCACTGAAAAAAGAAGCAGACTGGGACAGAAATGATGACAAAAGTGGAGAATCTTCATCAGAATATCGACTGCAACATGAATcgatgtGTTTGGATATGACATGTGGATCACCAAGTCTCTCCAGTCCGATAGCCCCCAGCAGCCCCACTGCGCTGCCCCTGTGGTCGCCTCTGCTAGCGTTGCAAGCCTGTCGTCTTCGCAGATATCTCAGTGATGATTGCATGGCATACCAAAGTCGACACTTGCTCCATACGGAAAGACGTCGTTGCGGTGTCTGTCTCGCTTCGTTCCCCACTACTTGGCTGCTAGAGCGTCATGCCGCCCTGCAACATGCGTCGCAAACCTCTACAGATGACAAGCCATTTGTGTGTGAACAATGTGGACAAAGCTACAGATACAGATCCGCCTATGTAAAACATAGAGAACAAAATCACAGAGCAAGGCTCCCGGCTGATAAACTTTTCACTTGCGACGTTTGCGGCATGCAGTTTCGATACCTCAAATCGTTCAAGAAACATCGTCTCAATCACACCCTCGAGAGACTGCACACTAAGAATACTGACCCACCTGAAGGCATAGACCAAGTATCTAGTACTAACGAAGTCTTGATTGGCCAGTGTGGAGAAATGGACTTGTCTATGAAGAAAAAGAATAGGACCGATGTGGCGAGAACACCGCCTATTGAAGTAATAGATGGGGAGCAAGACAGTACCGTAGATTCGAATGGAGCCACAGATTCTATAGTTACCGTCGATGACTCCAATGATTGCAAAAATTCTAGTGCTGAAAGCGAAAATAAAAAGGAAGATTCCGTCACCACTGAGAGGAGACGTGTTCCTGTGTCTTTCGCCAGTATCAGCTCTATGGCAGACAGCTCTGAGAGTGAGTCGCGCGGTGACAGCAACAAACTGGAAAGTTCCAGCTCACATTCCGGCATTTTGGGATATTTGCAAAACGACGACCGCCAGCGCGACCGGGAGAGGCGATTCGCGTGTCCGTTCTGCGGTAAATGCGTCAGGTCCAAGGAGAATTTGAAGTTGCACGTTAGGAAGCACACTGGGGAGCGTCCGTTCGTGTGCCTGTTCTGCGGTCGGGCGTTCGGCGGCAAGAGCGACCTGACCCGCCACTTGCGCATCCACACTGGGGAGCGCCCGTACCACTGCGAGGCGTGCGGCAAGTGCTTCGCGCGCGCCGACTACCTGTCGAAGCATCTCACGACCCACGTACACAATGCACGCTGA
Protein Sequence: MECEARICYVTFFPLEKCYAWNNHQSNLLGVFSQLLHDESLVDVTLACSEGASIRAHKVVLSACSSYFRSLFVDHPSRHPIVILKDVGLEELRTLVDFMYKGEVNVQYCQLPALLKTAESLQVKGLAEMTTLSAAGIDTRNVPEPMEECQQQDIREPIDSHERLDEREGRDKEERRDVKDSREFRDRECKDMRESHRDSREARDVREHRERDRERDREREREVARDRDARDQREHRDSRDHRELRDIKDNREPRDLREIRDSRDLRDNRDPREVPEASPPRISPLLSVRRFRPETSIETPTLTHPPIPKDEPPDEPMRPSSPEDDSVSIRSNGANDNMGINMTINSHGLGPRYSPVEQRLSVLNTLSHPGLPHPLSLSSPRNEPIAGPSGLPPVQQVPLSLKKEADWDRNDDKSGESSSEYRLQHESMCLDMTCGSPSLSSPIAPSSPTALPLWSPLLALQACRLRRYLSDDCMAYQSRHLLHTERRRCGVCLASFPTTWLLERHAALQHASQTSTDDKPFVCEQCGQSYRYRSAYVKHREQNHRARLPADKLFTCDVCGMQFRYLKSFKKHRLNHTLERLHTKNTDPPEGIDQVSSTNEVLIGQCGEMDLSMKKKNRTDVARTPPIEVIDGEQDSTVDSNGATDSIVTVDDSNDCKNSSAESENKKEDSVTTERRRVPVSFASISSMADSSESESRGDSNKLESSSSHSGILGYLQNDDRQRDRERRFACPFCGKCVRSKENLKLHVRKHTGERPFVCLFCGRAFGGKSDLTRHLRIHTGERPYHCEACGKCFARADYLSKHLTTHVHNAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00943167;
90% Identity: iTF_01507347;
80% Identity: iTF_00779606;