Hhim008027.1
Basic Information
- Insect
- Heliconius himera
- Gene Symbol
- ZEB2
- Assembly
- GCA_013421065.1
- Location
- JAATLT010025102.1:6761-8670[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.00066 0.05 14.2 1.2 1 21 143 163 143 171 0.92 2 9 0.021 1.6 9.5 5.6 1 23 184 206 184 206 0.98 3 9 6.1e-06 0.00047 20.6 1.0 5 23 215 233 212 233 0.96 4 9 3.4e-06 0.00026 21.4 3.9 1 23 239 261 239 261 0.97 5 9 0.00062 0.047 14.3 1.9 1 23 266 288 266 288 0.98 6 9 2.4e-06 0.00018 21.9 3.0 1 23 294 316 294 316 0.98 7 9 0.0016 0.13 13.0 3.9 2 23 323 344 322 344 0.97 8 9 6.5e-06 0.0005 20.5 2.8 1 23 350 372 350 372 0.99 9 9 4.7e-06 0.00036 21.0 2.2 1 23 378 401 378 401 0.97
Sequence Information
- Coding Sequence
- ATGGAAATACATCAACCTATTATGGAGTCAGCGGATTCAAAAATGTGTCGTATATGTTTACGAATTGTACAAAATACTTTAGAATTATTCTCCGCTGAAAAGAATTcaacagaaatattaaaaaagatttacgtTTGTTTTCAACTAACATTAAGatgtaaagaatattttccTTCATCTATATGCGTTACTTGCATACAAGACCTAAACACAGCCTATAACTTTCGTCAAAACTGCGAAACCTTCGAAAAACGATTTACTTTCTTATATCAAGAATCAATTACAGAAACCAATGTTCATAATACCACTCAACTTGGTAGTGGCGATTATTCAAAGCCAGACATTAAACTTGGAGATAATGATATTAAACTCAATGAAGGTGATGTAAAACATTGTAACCAAGTTGCAGatgattataataatctatTCATGTGTTCCATTTGTAAAAAAGTTCTCAAATCAGAAGCttcattaaataaacatacagtTGCGATGCATCAAAAGAGGAAACATCATGGTAAAGTTTCAGGTTTCGGTATCAATCGTCGTTATCATTGTACTAAATGTTTATACAACACGCCTCACAGCCAGACTCTAGTGAATCATATGAGGAAACATAGTGGTGATCGTCCATTTCAGTGTGAGTGTGGTAAAAGCTTTACACAGTCCGCCAGTCTAAATGCACATCGTAAGACTCATAGTAATACAACATATTTCACTTGTTCAAAATGTGGAAAGCAATTTAAGCATGCATTTTCATTAAAGAAACATTTAGATGTACATGAAATAGGCAAATTTAAATGTGACATATGCCTCAAGCAGTTGAAATCCAGACAAACCTTACAGGACCACATGTATCGTCATTATAATGTTAAGAACTATAATTGCGAAGATTGTGGGAGGACATTTGTAACTTGCTCTGAACtactaaatcataaaaaaaaacataatgcgGTTAAGGAAGTGGAATGTCACTTGTGTGGATATAAAACACATACTAAAAAAAGCTTGATTATTCACTTGAAAAGacaTGCTGGGGACAAATCTTATAAATGTGATTTATGTCATGTATCATTTTTCACAAATGGTGACTTGCAACGTCATAAGAGAGTGCACACACGAGATAAGCCTTTCCCCTGCCCTACTTGTGTACAAAGATTTACACATAGCACAAGTTTAAATAAACACATGAAGTCTGTGCACGGGATAGATTGCAAATGGGCAGACATTAAAATGAAGAACTTCACCAAGGATAAAATAgatgcaaaaataatttaa
- Protein Sequence
- MEIHQPIMESADSKMCRICLRIVQNTLELFSAEKNSTEILKKIYVCFQLTLRCKEYFPSSICVTCIQDLNTAYNFRQNCETFEKRFTFLYQESITETNVHNTTQLGSGDYSKPDIKLGDNDIKLNEGDVKHCNQVADDYNNLFMCSICKKVLKSEASLNKHTVAMHQKRKHHGKVSGFGINRRYHCTKCLYNTPHSQTLVNHMRKHSGDRPFQCECGKSFTQSASLNAHRKTHSNTTYFTCSKCGKQFKHAFSLKKHLDVHEIGKFKCDICLKQLKSRQTLQDHMYRHYNVKNYNCEDCGRTFVTCSELLNHKKKHNAVKEVECHLCGYKTHTKKSLIIHLKRHAGDKSYKCDLCHVSFFTNGDLQRHKRVHTRDKPFPCPTCVQRFTHSTSLNKHMKSVHGIDCKWADIKMKNFTKDKIDAKII
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00778196;
- 90% Identity
- iTF_00775461;
- 80% Identity
- -