Hhew014440.1
Basic Information
- Insect
- Heliconius hewitsoni
- Gene Symbol
- ZEB2
- Assembly
- GCA_018230445.1
- Location
- DWAN01016481.1:1139-3551[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.00015 0.012 16.6 0.8 1 23 142 165 142 165 0.94 2 9 0.027 2.2 9.5 5.6 1 23 183 205 183 205 0.98 3 9 8e-06 0.00066 20.6 1.0 5 23 214 232 211 232 0.96 4 9 4.5e-06 0.00037 21.4 3.9 1 23 238 260 238 260 0.97 5 9 0.00081 0.066 14.3 1.9 1 23 265 287 265 287 0.98 6 9 3.1e-06 0.00025 21.9 3.0 1 23 293 315 293 315 0.98 7 9 0.0022 0.18 13.0 3.9 2 23 322 343 321 343 0.97 8 9 8.5e-06 0.0007 20.5 2.8 1 23 349 371 349 371 0.99 9 9 2.4e-06 0.00019 22.3 2.9 1 23 377 400 377 400 0.97
Sequence Information
- Coding Sequence
- ATGGAAATACAACAATCTATTACGGAGTCAGCGGATTCAAAAATTTGTCGTATATGTTTACGAATTGTACAAAATACTTTAGAATTATTCTCTACTGAAAAGAATTCAACagagatattaaaaaagatttacgtTTGTTTTCAAGTAACATTgagatataaagaatattttcctTCATCTATATGCGTTACTTGCATAGAAGACCTAAACACTGCCTACAATTTTCGTCAAAACTGTGAAACCTTCGAAAAACGTTTTACTTTCTTATACCAAGATTCAGTAACAGAAACTAATGTTCATAATACTACTCAGCTTGGTAGTGACGATTATTCAAAGTCAGACAAACTTGgagatgataatattaaactcGATGCAGGTGATGTAAAACATTGTAAACAAGTTGcagataattacaataatatattcaagtgTTCCATTTGTAAAAAAGTTCTCAAATCAgaagtttcattaaataaacatacagtTTCGATGCATCAAAAGAGGAAACATCATGGTAAAGTTTCAGGTTTTGGTATCAATCGTCGCTATCATTGTACTAAATGTTTATACAACACTCCTCACAGCCAGACACTAGTAAATCATATGAGGAAACATAGTGGTGATCGTCCATTTCAGTGTGAGTGTGGTAAAAGCTTTACACAGTCCGCCAGTCTAAATGCACATCGTAAGACTCATAGTAATACAACATATTTCACTTGTTCAAAATGTGGAAAGCAATTTAAGCATGCATTTTCATTAAAGAAACATTTGGATGTACATGAAATAGGCAAATTTAAATGTGACATATGCCTCAAGCAGTTGAAATCTAGACAAACCTTACAGGACCACATGTATCGCCATTATAATGTTAAGAACTATAATTGTGAAGATTGTGGGAGGACATTTGTAACTTGCTCTGAACtactaaatcataaaaaaaaacataaggcGGTTAAGGAAGTGGAATGTCACTTATGTGGATACAAAACACACActaaaaaaagcttaattaTTCACTTGAAAAGacaTGCCGGGGACAAATCTTATAAATGTGATTTATGTCATGTATCATTTTTCACTAATGGTGACTTGCAACGTCATAAGAGAGTGCACACACGAGATAAGCCTTTCCCCTGTCCTACTTGTACACAAAGATTTACACATAGCAcaagtttaaataaacacatGAAGTCTGTGCACGGAATAGATTGCAAATGGGCAGACATTAAAATGAAGAACTCCACCAAGGATAAAATAgttgcaaaaataatttaa
- Protein Sequence
- MEIQQSITESADSKICRICLRIVQNTLELFSTEKNSTEILKKIYVCFQVTLRYKEYFPSSICVTCIEDLNTAYNFRQNCETFEKRFTFLYQDSVTETNVHNTTQLGSDDYSKSDKLGDDNIKLDAGDVKHCKQVADNYNNIFKCSICKKVLKSEVSLNKHTVSMHQKRKHHGKVSGFGINRRYHCTKCLYNTPHSQTLVNHMRKHSGDRPFQCECGKSFTQSASLNAHRKTHSNTTYFTCSKCGKQFKHAFSLKKHLDVHEIGKFKCDICLKQLKSRQTLQDHMYRHYNVKNYNCEDCGRTFVTCSELLNHKKKHKAVKEVECHLCGYKTHTKKSLIIHLKRHAGDKSYKCDLCHVSFFTNGDLQRHKRVHTRDKPFPCPTCTQRFTHSTSLNKHMKSVHGIDCKWADIKMKNSTKDKIVAKII
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00778196;
- 90% Identity
- iTF_00775461;
- 80% Identity
- -