Hcyd014348.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Heliconius cydno
Gene Symbol
ZEB2
Assembly
GCA_036379175.1
Location
FAPN01037524.1:1-2514[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00021 0.027 15.9 0.4 1 23 146 169 146 169 0.93
2 9 0.0055 0.71 11.5 6.0 1 23 186 208 186 208 0.98
3 9 6.8e-06 0.00088 20.6 1.0 5 23 217 235 214 235 0.96
4 9 3.8e-06 0.00049 21.4 3.9 1 23 241 263 241 263 0.97
5 9 0.00069 0.088 14.3 1.9 1 23 268 290 268 290 0.98
6 9 2.6e-06 0.00034 21.9 3.0 1 23 296 318 296 318 0.98
7 9 0.0015 0.2 13.2 3.9 2 23 325 346 324 346 0.97
8 9 2.2e-06 0.00029 22.1 3.6 1 23 352 374 352 374 0.99
9 9 2e-06 0.00026 22.3 2.9 1 23 380 403 380 403 0.97

Sequence Information

Coding Sequence
atgGAAATACAACAACCTGTTATTGAGACAGCGGATTCGAAAATTTGTCGTATATGTTTACGAATTGTACAAAATACTGTACAATTATTCTCTGCTGAAACAAATTcaacagaaatattaaaaaagatttacgtTTGTTTTCAAGTAACATTgagatataaagaatattttcctTCATCTATATGCGTTACTTGCATAGAAGACCTAAACAATGCCTATAATTTTCGGCAAAACTGCGAAACCTTCGAAAAACGTTTTACTTTCTTGTTCCAAGAATCAATAACAGAATCTAATGTTCATAATACTGCTCAGATTTGTTGTGACGATTATACAAAGTTAGACAGTAGACTGGaagatgataatattaaacttgaagttccTTTTTCAGGTGATGCAAAACATTGTAACCAAGTTGCagatgattttaataataaattcatgtgTTCCATTTGTAAAAAAGTTCTCAAATCAGAAGcttcattaaataaacatacagtTTCCATGCATCAAAAGAGAAAACATGGTAAAGTTTACGGTTTTGGTATCAATCGTCGTTATCATTGTACTAAATGTTCATACAACACACCTCACAGCCAGACATTAGTGAATCACATGAGGAAACATAGTGGTGATCGTCCATTTCAATGTGAATGTGGTAAAAGTTTTACACAGTCTGCCAGTTTAAATGCACATCGTAAGACTCACAGTAATACAACATATTTCACTTGTTCAAAATGTGGAAAGCAATTTAAGCATGCATTTTCATTAAAGAAACATTTAGATGTACATGAAATAGGCAAATTTAAATGTGATATATGCCTCAAGCAGTTGAAATCCAGACAAACCTTACAGGACCACATGTATCGTCATTATAATGTTAAGAACTATAATTGTGAAGATTGTGGGAGGACATTTGTAACTTGCTCCGAACtactaaatcataaaaaaaaacataatgcaGTTAAGGAAGTTGAATGTCACTTATGTGGATATAAAACACATACTAAAAAAAGCTTGATTGTTCACTTGAAaagacaTGCTGGCGACAAATCTTATAAATGTGATTTATGTCACATATCCTTTTTCACAAACAGTGACTTGCAACGTCATAAGAGAGTGCATACACGAGACAAACCTTTCCCCTGCCCTACTTGCACACAAAGATTTACACATAGCacaagtttaaataaacacatgAAATCTGTACATGGTATAGATTGCAAATGGGCAGACATTAAAATGAAGAACTTTACTAAGGATAAAATAgttgcaaaaataatttaa
Protein Sequence
MEIQQPVIETADSKICRICLRIVQNTVQLFSAETNSTEILKKIYVCFQVTLRYKEYFPSSICVTCIEDLNNAYNFRQNCETFEKRFTFLFQESITESNVHNTAQICCDDYTKLDSRLEDDNIKLEVPFSGDAKHCNQVADDFNNKFMCSICKKVLKSEASLNKHTVSMHQKRKHGKVYGFGINRRYHCTKCSYNTPHSQTLVNHMRKHSGDRPFQCECGKSFTQSASLNAHRKTHSNTTYFTCSKCGKQFKHAFSLKKHLDVHEIGKFKCDICLKQLKSRQTLQDHMYRHYNVKNYNCEDCGRTFVTCSELLNHKKKHNAVKEVECHLCGYKTHTKKSLIVHLKRHAGDKSYKCDLCHISFFTNSDLQRHKRVHTRDKPFPCPTCTQRFTHSTSLNKHMKSVHGIDCKWADIKMKNFTKDKIVAKII

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00778196;
90% Identity
iTF_00781229;
80% Identity
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