Basic Information

Gene Symbol
-
Assembly
GCA_037355905.1
Location
JBAIZZ010000305.1:1799342-1802007[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.33 20 6.0 0.2 2 23 75 97 74 97 0.94
2 18 0.48 29 5.6 2.5 2 23 121 142 120 142 0.95
3 18 0.11 6.6 7.6 3.3 1 21 146 166 146 169 0.95
4 18 1.2 72 4.3 0.5 1 21 174 194 174 195 0.94
5 18 0.031 1.9 9.3 1.0 1 23 202 225 202 225 0.90
6 18 0.0025 0.15 12.7 4.4 1 23 232 255 232 255 0.96
7 18 0.18 11 6.9 1.3 1 20 260 279 260 280 0.95
8 18 0.0038 0.23 12.1 1.5 3 23 335 356 334 356 0.97
9 18 0.74 44 5.0 0.0 2 23 381 403 380 403 0.94
10 18 0.0022 0.13 12.9 0.4 3 23 428 448 426 448 0.96
11 18 0.00049 0.03 15.0 0.7 1 21 452 472 452 473 0.96
12 18 1.3 76 4.2 0.4 1 23 514 537 514 537 0.95
13 18 0.31 19 6.1 0.3 2 23 563 585 562 585 0.96
14 18 0.025 1.5 9.6 1.1 2 23 609 630 608 630 0.95
15 18 0.00017 0.01 16.4 0.0 1 23 634 657 634 657 0.97
16 18 0.04 2.4 8.9 0.5 1 23 661 684 661 684 0.97
17 18 0.00042 0.025 15.2 1.8 1 23 723 746 723 746 0.97
18 18 0.0017 0.1 13.2 1.5 1 23 756 779 756 779 0.95

Sequence Information

Coding Sequence
ATGACTAAACGGAACGCAGAACTCGTGTTGCTGTATTCAACGGTATACCCGTTCAGAATTCGCAGCAAGACAATGATATGCGTTTATTGCTGTGAAGACTACGAAGACCCAAAAGACTATAGAATTCATTTGGACGAGGCTCACAAAACTTTTACGGTATCTACTGCCTTAGCGCATTGTGGATACGGCAAAGAATACCTTAAAGTCGACCTCACAGATTTAAAATGCAGAATATGTTCTCTGCCTTGTAATAATTTGGAAGAAATCGCTGAACATATTAGAGACATTCACAGCGTAAACAAAATTgacttaaattatgaaattggtATGCATCCTTATAGAATGGACGGCGAAAAGTGGGTTTGCTTTCTCTGTGACAAAAAGATGCCATCGTTGACCAAATTATGTAGACATACAACTTCACACTACCAAAAGTATACGTGCGATGTTTGTGGGCGGgcttatttgaaaaatgagGCATTGAAATATCATATCCGATGCTGTCACACTTATGGAAATCATGTATGTAGAAAATGTTGGATAGATTTCCCAACATTAGAAAAGAAACGAGAGCATTTAAGACAATCGAAACGCTGTTGGACCTTCTGTTGTACCAGTTGTGGAGAACGTTTTATGTCTTGGGAAGCCAAGCAGAAACATCTTGTAGAAGTACACGGGAAGCAAAAGAAGATACATGAATGTCCTGATTGTGAGGAAACCTTCGAGTCACGAAAACATTTCTATACTCACTTTAAAGTTAATCACAGTGATGACAGCTACGTATGCTCTTGTTGTGGACTGAAATATGTCACCAAAAAAGAACTGGAGGAGCATAGATTCTGTCATACCGggtCGACATTGGAAATTCGAGGGCGTAGTGAGAATGAAactgagaaaaagaaaatagtactCGTATATCAGACGCCTCAGCGTCGAAACGCGGAACTTATACTCAGGCATTCCACCGCCTATCCATTTAAAACACGTTTTAGTCAAATATTATGTGCATATTGTCACGATGAGTATAACACTTTGTCTAATCTTCGATATCACATGAAAACGGAACATGTCAATactgattttaaaaatgttttctttagaACTAAAGACAATTTAGTTAAAGTTGATATTACTAatcttaaatgtaatatttgtagtcAGGATATAGTAGATATAGATAGCTTAATGGGCCATCTATCTAGAGAGCACAACAAATCAGTTAAATTTAACGCGCGTTTTGGTGTATTACCATACAAACAAAATGCAAACGATCAATGGATATGCgtgtattgtaaaaaaacttatgtagaatttattcaatttaaacgaCATATAGCAAcacattttatgaattttagcTGTGACAAGTGTGGTACAACTTTCATATCTGATCACGCCTTGCGAGATCATCGACGTCAGGTTAAATGTTTTAGGACTGCATACAAGCCTCGAAATGGCAGAGTAATGAAACCTCGTACAAACGCAGAAATTATTCTTCAATGTTCCACTGCCTGTCCATTTAGGACATGGAAAAGcaattttaattgtgttttcTGTAGAGTACAATCAAGCGATCCAAGTATACTTCGAACTCATATGGTGACTCGCCACGAAAACTATGATGTACAAGcagctttttataaaaaattaggtAAAGAATTTCTTAACATTGACATAACTGACCTTCAATGTAAACTATGTTTTATTCCTATTGAAAATTTCGAAACTTTAACATATCACTTAAAGACTGATCATCAACAGCCAATAAATTCAGATGCCCAACTGGGTGTCTTGCCTTTTCGGTTAAACGACGGCTCGATTTGGAAATGCGCAATGTGTTCGAATGagtttaaagattttgtatcattaaaaaaacacacatcCCAACACTTTCAGAATTACGTATGTGATACTTGTGGCGAAGGTTTCATTACTGAATCGGCCATGATAGCACATACTAAAAAAccacatgaaaataaatataattgtagtcGATGTGTGGCAACTTTTTCCAGTTTGGAGGAGAGAAATGTTCATGTTAAAACACAACATACCTCGACCCCGTATATGTGTGTTTACTGTAAAGATAAGCCTCGTTTTGCTAATTGGGAGATCCGGAAGAAACATCTAATGGAAGTCCATAATTATAAGACTGGTGCTGATAAATATGAATGTGCTACTTGTCagaaatcttttaaaactCGATCaggaaaatataatcatatggCAAGAACTCATAGAGTAAAAAAAGATACTGAATTAAAATACCCGTGCCATAGTTGTCCGAAGGCTTTCACAACTCAGTTATTTTTGGATAAACATGTTGCGAAGAAgcattttgatatttga
Protein Sequence
MTKRNAELVLLYSTVYPFRIRSKTMICVYCCEDYEDPKDYRIHLDEAHKTFTVSTALAHCGYGKEYLKVDLTDLKCRICSLPCNNLEEIAEHIRDIHSVNKIDLNYEIGMHPYRMDGEKWVCFLCDKKMPSLTKLCRHTTSHYQKYTCDVCGRAYLKNEALKYHIRCCHTYGNHVCRKCWIDFPTLEKKREHLRQSKRCWTFCCTSCGERFMSWEAKQKHLVEVHGKQKKIHECPDCEETFESRKHFYTHFKVNHSDDSYVCSCCGLKYVTKKELEEHRFCHTGSTLEIRGRSENETEKKKIVLVYQTPQRRNAELILRHSTAYPFKTRFSQILCAYCHDEYNTLSNLRYHMKTEHVNTDFKNVFFRTKDNLVKVDITNLKCNICSQDIVDIDSLMGHLSREHNKSVKFNARFGVLPYKQNANDQWICVYCKKTYVEFIQFKRHIATHFMNFSCDKCGTTFISDHALRDHRRQVKCFRTAYKPRNGRVMKPRTNAEIILQCSTACPFRTWKSNFNCVFCRVQSSDPSILRTHMVTRHENYDVQAAFYKKLGKEFLNIDITDLQCKLCFIPIENFETLTYHLKTDHQQPINSDAQLGVLPFRLNDGSIWKCAMCSNEFKDFVSLKKHTSQHFQNYVCDTCGEGFITESAMIAHTKKPHENKYNCSRCVATFSSLEERNVHVKTQHTSTPYMCVYCKDKPRFANWEIRKKHLMEVHNYKTGADKYECATCQKSFKTRSGKYNHMARTHRVKKDTELKYPCHSCPKAFTTQLFLDKHVAKKHFDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00780525;
90% Identity
iTF_00780525;
80% Identity
-