Basic Information

Insect: Harpegnathos saltator
Gene Symbol: zfh1
Assembly: GCA_003227715.1
Location: NW:25301-57375[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1.5 99 3.2 1.0 2 23 119 141 119 141 0.90

2 7 2e-05 0.0013 18.5 0.6 2 23 160 181 159 181 0.97

3 7 4.9e-06 0.00031 20.5 7.8 1 23 190 212 190 212 0.99

4 7 9.8e-06 0.00062 19.5 1.3 1 20 218 237 218 239 0.96

5 7 0.00019 0.012 15.5 4.5 1 23 683 705 683 705 0.94

6 7 6.1e-05 0.0039 17.0 7.1 1 23 711 733 711 733 0.98

7 7 0.0013 0.082 12.8 4.3 1 21 739 759 739 760 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1.5	99	3.2	1.0	2	23	119	141	119	141	0.90
2	7	2e-05	0.0013	18.5	0.6	2	23	160	181	159	181	0.97
3	7	4.9e-06	0.00031	20.5	7.8	1	23	190	212	190	212	0.99
4	7	9.8e-06	0.00062	19.5	1.3	1	20	218	237	218	239	0.96
5	7	0.00019	0.012	15.5	4.5	1	23	683	705	683	705	0.94
6	7	6.1e-05	0.0039	17.0	7.1	1	23	711	733	711	733	0.98
7	7	0.0013	0.082	12.8	4.3	1	21	739	759	739	760	0.96

Sequence Information

Coding Sequence: ATGAGCATGACTCTCGTTCGAAATTCGTTCAAAGCTCGTCTTGGATGTACGGAGACCGCAGACACTCGGATTGGCTCCATCGTTTCgaGCTGCAGCGAGGACGACGCAGGTGTCGTGGATGCGGAGGTAGGCGGAGGTTGTGCGGGTGGAGCACCAACCGGAGGAGGTGGAAGTATTGCCGGTGatggaggtggtggtggtggtggtggtggtggtggcggtggcggtagtGGTGGCGGCGGCTGCGGTGGAGGTGGCTGCGGAGGGCGAGGAGCTGGTGAGGGTGGTTCAgcgaagcagcagcagcagcaacaacagcagcagcagcagcagcagcaccaaCAGGGTGGCGAAAGGTGCTCTCAGTGCGGCATCCTCTGTCGGGACGTCCATGTCCTGCAGCTTCATCTCGAGGACGCGCACAAAACATCCTATCCCATTGATAAGCACGATCTCAACGCCCAGTTCTCCCAAGTGTCTTGCAAGGTGTGTAGCAAAACTTTCGCTAACGTCTATCGACTACAGAGGCATATGATCAGTCATGATGAAAGTGCCGTTCTGCGAAAGTTCAAATGTCCTCATTGCGAGAAGGCCTTCAAGTTCAAgcatcatcttaaaGAGCATCTGCGCATTCACAGCGGAGAAAAGCCATTCCAGTGCAACAATTGCGGCAAGCGTTTCTCTCATTCTGGATCGTACTCGAGCCATATGACGGCGAAGAAATGCTTGATAATGAATCTGAAGAAGTCCAGGCAGAATACCATAAGCAACGTCGATCGGGGACCGAAGAAAGCGCATCAGCCGTTGTCAGGACGACGCGACGTTGATCCGCTTGCCAATAATAACACGTTCCTTCCGATTCTGCCGAAGCTGTCACCTTCAGAATATCAAGATATGCAAAGGGAGGGTACAGGTGTCTACGACATGCCGCCGTCCTTGCTACCCTCGATGATCGGTTTGGGAAGTTATTTTCTGCAGACTTCACTGGGTAAACTCTTACATCACTTGCATACTAAGCGAATCGATGAGCTTACTGAACATTTCGAGACGCATCGGGAAGTAATGAGTCCATCAACAGCGGACTCTGAGGGAACGGAAGGCACAGAGGGCAAAGAGTCTCCCGCGCCAGCTGACTCTCAGGGTCTTGACGCTGTCCGGCGAATTTTAGAGACCGTGAATACTTCCGTCACGAAGCAGTTACTGGAAGCGAATGTGCGGAAGCTCTCCACGTCTCCAGCTATAACGAAACGAGAGTTTGAGGAGGATTATCAAGATCAAGATAGTGAGATGTCCAGTGAGATGACACATTGTCCGGACTGGGCTGCGACGGATCAATATGATTCACAGAGTGAAGGTTTAGCCGCAAAGCTCGAGAACGTCAATCAACCAACGTCGAGATCAACCTacaagagaaaaagggaggacAGTTCTGAGGCGGATTCAGAGGATGAGGATGAAGGGAATCAAACTCACAACGACAATGGCAGGCGGGTGAGAGCTAGATCACTCATAGATGATGAACAGTTGGCTGTTCTGAAGGGTTACTATGCTATTAACCCGCGTCCTAAGAAGGAGGAGATCAATATGATCGCCGATTACATTAAGTTTCCTACCCGTGTTGTACAGGTTTGGTTTCAAAATTCTCGAGCCAGGGATCGAAGGGAATCGAAGGGAATGCCAGGTCTGGTACCTTTGACACTACCAAGAAATCAGGCTGTAATCGAGCAACCCTTGGATCTCTCTAAAAAGGAAGCGCTTGCTATGTCGACAACCAAAGAAAGCGATACGTCGAGTAGAAATACTTCATCTCCCTGCGAGCAGAAGGATGATAATAATCCAGCCCCGAACGTCGACAACGATGATCTCGAGGATTCACCTCTCGTCATAGATGAAGAAACTACTACTGACCCTGTTGAAGTCAAGCGTATACCACCAACTGGAGAGATAATTGCGAAGAGCCAAAATCAAGTGAACGCGAAAGGCGAAAGTGAGGTTATACCTCAACCAGAAGTAACCCCCATAGCAACGGAAACCGAGCAGGGTCTTTATTTCTGTGATCGGTGCGACAAAACATTTTCCAAACACAGTTCCCTCGCGAGACACAAGTATGAACATTCCGGGCAAAGGCCGTACAAATGCGTGGAGTGTCCCAGAGCGTTCAAGCACAAGCATCATCTGACTGAACATAAACGGCTGCACAGTGGCGAAAAGCCCTTCCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCCGGCTCCTATAGCCAGCACATGAATCATCGTTACTCTTACTGCAAGCCCTACAGAGAATAG
Protein Sequence: MSMTLVRNSFKARLGCTETADTRIGSIVSSCSEDDAGVVDAEVGGGCAGGAPTGGGGSIAGDGGGGGGGGGGGGGGSGGGGCGGGGCGGRGAGEGGSAKQQQQQQQQQQQQQHQQGGERCSQCGILCRDVHVLQLHLEDAHKTSYPIDKHDLNAQFSQVSCKVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTAKKCLIMNLKKSRQNTISNVDRGPKKAHQPLSGRRDVDPLANNNTFLPILPKLSPSEYQDMQREGTGVYDMPPSLLPSMIGLGSYFLQTSLGKLLHHLHTKRIDELTEHFETHREVMSPSTADSEGTEGTEGKESPAPADSQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPAITKREFEEDYQDQDSEMSSEMTHCPDWAATDQYDSQSEGLAAKLENVNQPTSRSTYKRKREDSSEADSEDEDEGNQTHNDNGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEINMIADYIKFPTRVVQVWFQNSRARDRRESKGMPGLVPLTLPRNQAVIEQPLDLSKKEALAMSTTKESDTSSRNTSSPCEQKDDNNPAPNVDNDDLEDSPLVIDEETTTDPVEVKRIPPTGEIIAKSQNQVNAKGESEVIPQPEVTPIATETEQGLYFCDRCDKTFSKHSSLARHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01421778;
90% Identity: iTF_00452807;
80% Identity: iTF_00769529;