Basic Information

Insect: Harpegnathos saltator
Gene Symbol: znf423
Assembly: GCA_003227715.1
Location: NW:57797-64762[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.089 5.7 7.1 2.2 9 23 17 31 16 31 0.92

2 18 0.00017 0.011 15.6 0.2 1 23 37 59 37 59 0.99

3 18 0.00071 0.045 13.7 2.4 1 23 224 247 224 247 0.97

4 18 0.07 4.5 7.4 0.1 2 23 258 280 257 280 0.89

5 18 0.16 10 6.3 0.1 3 23 370 390 369 390 0.97

6 18 0.0018 0.12 12.4 0.4 1 23 402 424 402 424 0.97

7 18 0.011 0.7 9.9 0.3 1 23 433 456 433 456 0.92

8 18 4.8 3.1e+02 1.6 0.2 1 23 461 484 461 484 0.90

9 18 0.29 18 5.5 2.0 2 23 562 583 562 583 0.96

10 18 0.0098 0.63 10.1 0.0 1 23 588 611 588 611 0.93

11 18 2.6 1.6e+02 2.5 0.1 2 23 684 707 683 707 0.81

12 18 3.9e-05 0.0025 17.6 1.0 2 23 724 746 723 746 0.96

13 18 0.032 2 8.5 1.0 1 23 755 778 755 778 0.93

14 18 4 2.5e+02 1.9 0.1 3 23 787 807 785 807 0.94

15 18 0.0085 0.54 10.3 0.0 2 23 974 996 973 996 0.92

16 18 2.4 1.6e+02 2.5 0.2 2 23 1030 1051 1029 1051 0.93

17 18 0.092 5.9 7.0 0.1 1 23 1059 1082 1059 1082 0.93

18 18 0.53 34 4.6 3.8 1 23 1089 1112 1089 1112 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.089	5.7	7.1	2.2	9	23	17	31	16	31	0.92
2	18	0.00017	0.011	15.6	0.2	1	23	37	59	37	59	0.99
3	18	0.00071	0.045	13.7	2.4	1	23	224	247	224	247	0.97
4	18	0.07	4.5	7.4	0.1	2	23	258	280	257	280	0.89
5	18	0.16	10	6.3	0.1	3	23	370	390	369	390	0.97
6	18	0.0018	0.12	12.4	0.4	1	23	402	424	402	424	0.97
7	18	0.011	0.7	9.9	0.3	1	23	433	456	433	456	0.92
8	18	4.8	3.1e+02	1.6	0.2	1	23	461	484	461	484	0.90
9	18	0.29	18	5.5	2.0	2	23	562	583	562	583	0.96
10	18	0.0098	0.63	10.1	0.0	1	23	588	611	588	611	0.93
11	18	2.6	1.6e+02	2.5	0.1	2	23	684	707	683	707	0.81
12	18	3.9e-05	0.0025	17.6	1.0	2	23	724	746	723	746	0.96
13	18	0.032	2	8.5	1.0	1	23	755	778	755	778	0.93
14	18	4	2.5e+02	1.9	0.1	3	23	787	807	785	807	0.94
15	18	0.0085	0.54	10.3	0.0	2	23	974	996	973	996	0.92
16	18	2.4	1.6e+02	2.5	0.2	2	23	1030	1051	1029	1051	0.93
17	18	0.092	5.9	7.0	0.1	1	23	1059	1082	1059	1082	0.93
18	18	0.53	34	4.6	3.8	1	23	1089	1112	1089	1112	0.96

Sequence Information

Coding Sequence: ATGctttctcttcgttttcgtCTTACAAACTCCTTCGGATACATTCAACGTTTTTTTTCCAGCGATCACCTAAAGATCCACATGAAGACGCACGACACGCAGAAGCCTTACCAATGCACAGCTTGCTCGAGGGGTTACAACACAGCTGCGGCACTAACATCGCACATGCAGTCCCACAAGAAGCATCATCAATCGTCCTCTCAGTCAACTGGCGGCAAGCTTCACGACGTCGACTACGGCAGACGGAGCGTCTCGTCGCACAGCACGTCGTCGCCACCGGTGCcgagttcgccgtcgccgtcccTGAATCTGGGCCTGAATCCAAGGCCGAATGCTCTGAAAACTTCTCAGAGCACCTGCAGCGCTTCCACCACGCCCGTTCTGAGCTCCCCCTTGAAGCTGACCTGCATGTACTGCACCAAAGACTCGTTCAGTTGTATGCAGCAATTGCAGATGCACGTGCATTCGATGCATCAGGCGATACTAAGCGGCGAGAGTCTGGTTGTACCACCGTCACCCAGCGGGACGAATGAGCAGATTACCCCAGGTTCGCGCGACAAGTCGTTGGCGGACCGGCAGGTGGACGGCTTGTCGTCAAAGGACTCGCGCGATCGGAAATATCCGGAGGATCGCGAGAGACCCGGTGAAAGGGACCACTACGAGAACGCGTTCACGTGCAATCAGTGCACCATGAAGTTCTCCACGCTGGGCTGCCTGCGCGATCACTTGCTGTCGATACACCGACTCGGTGCGTTCGGCGCGGCGATGATGATGTGCCCATTGTGCGGCATCCCGTGCTCGTCCGCAGCCTCCTATGCCGAGCACTACGTTCTCCAGCACTGCGAGAATCGTCGGATCGCGCCGACAGCCGCGATCGAGTACGGCGAGCCGAAGGTGAATGGCGTCTACGACGGCGTCACGAGAGACACGAGATTGCAAAGGAGCACGGACGTGCAGCCGGAAGCAGCGGATCTTACAAACAAACACTCCGTCAgacccaccaccaccactaccaccatcactaccaccaccaccaccaccaccaccaccactaccaccacaaACGACgccgggggcggcggcggctacaCCGCCGGTACCCTTCTGTGCGGTCAATGCGGCGCCGCTTTGAAGGACTTCGAGTCGTTCCGGGAACATCTGGCACGACACCTGCAAGCTGATCATCGTAACGAAGTGTCCAGGCACCCATGCTCCAAGTGCGAGGCGACCTTCCCGGACCGCGAGGATATGCTGAATCATCTGATTAAGCATTACCTGGGCCAAGTCAGCAAGGAGTACGCCTGCGGCGCCTGCAAGAAGCTCTACCCGCATCCCGACCTCCTTCAGAGGCACCTGCTGGATAGTCACGCGCACCATTTGTACCGATGCGCTCTGTGCCGGGACACGTTCGACTCCCGGGTGGCGATCCAGTTGCACTTTGCTGTGAAACACAGCCAGGAATGCCGGGTCTATCGGTGCAGCGCGTGCTGCACCTTGTCCAATAATGAGAACTCGCCGGGGAACGCGCCCGGCGAGGGCAGGAGCTTCTTCAGGAGCGAGGCCGAGATGGCGGCGCACGTCCGTAACGTGCacgcgccgcccgccgccctGATCAACAGTAGTCCAGGCTTGGCGAGGAGTCCCGCCTCGACGCCGGGTATCACCAGCGGCGGCGCCGCGGCACGTTGCGTCTTTTGCGGCGTCTGCTGCAACTCGGAGCTCGAGCTGCAACTTCACCTGGCCAGCCACTCCGCCAGTCTCTACAGGTGTCCTGTCTGCAAGGAGGGATTCGCGGTGGAGTTTCTGCTGGACAGGCACGTCGCTCAGGCGCACGCGGGGGATCATCGTCCGGCTTCATCGTCCGTCAGGaacagggagagggagagggagagggagagggagaacggCCGGGTTCATCGACCGGTCAGAAATCAGGAGGAGCCGAAATCTCTCAAGCGAGGCCGCTCGCCAGCGTCTAGCAACAACAACTCCCTGAACCAACgcgacaacaacaacaagcGACCGAACTTTGGCACTTCCGGCGGTCAACAGTGCGAGCTCTGCGAGCGCGGTGAGTTCGCGAACGAGGCCGAGCTGCAGGCGCACAAGAAACTAGTTCACACGCCCTCCAAGTTGCCCAGCAGCAAGAGCGTATCCGCCCTGAGCATGACCTGCGCGTACTGCGGCGAGGTTTGCCGTTCCCGTAGCGAACTGGAGTCGCACACCAGGATCCAGCACGCGTCCAACGAACCGGGTGGACGTCACAAGTGCAACATCTGCGACGAGGTGTGCCCGTCCGGGGCGACCTTAGCCGAACACAAACTCCAGAAGCACTGCAAGATCCAGTTGAGCGACATCTGCGTGGTGTGTCGCGGTCGCCTCGCCTCGGAGAGCCAGTTCCTGGAACACGTGCAGAGGCACAGCCTAGAGAACGTGGATCCGCAGCAACGGCTGGACAATTCGCTGCCTCATTTGCCGGCGCCGTGCGTGATCTGCCGGCAGACGCTGATCAGCGACCTGGAGTGCCGTCTGCACGCCAGGCATCACCTGAGGACGTCGTCAGGATCGCACAGCGACGGATCCAGCCCGGCGAGTCCCGCCGCTAAGGCCGCTCAGAGCCCAGGTTGCTGCTTCTGCTTGCGGGATTTCGCGGCGGACGACTTTGTCAGCTTGCCGCCCAATCATGCCAGCGCGGGTGGACAGCCGCTCAGAGTCTGCAAATCCTGTTACGTGCGACACTCTCAAGGACTTCCTATCCTGAATTCCACGTACGAGCAGCGAGCCAAGTACGAAGCGGCATGGCTCGCTCAGAACAAGGACGCTCAGTGGGACAGTTCCCACAAGGACAAGTGGGAGAACGGAAGGGGCCTCAAGGCGGAGGATCGAccgaggaaggaaagaaatgCGGATAACAACAAGCGCTGCGAAGAGTGCGGGGTCAAATTTGAGGATCCTGAGGAGGCGGAGAAGCACAGGATAGCCGAGCACCGCGAGAAGGTGCCCTTTGCGACCGAAGCCAAGGTTCAACAACATGTAAGGAAGGAGCACCTCTGCGACACTTCTGCGAAATCCTCGTTGGAAGCTTTGCGGTGTCATTTGTGTTTATTCGAGGCCGCGAGCCCTTTGCAGTTGCAAAGTCACCTGATAGAACACACGTTTGCCGGATGCCCTGCCTTTAACTGCTACATCTGCCAGGCGCTTTTTACAGCTCCTGTTGGCCTTCAGAATCACATGGTGCAAGAGCACGGCCTCGGTGCGCGACCGTACGATTGTTCCAAATGCACGCTCAAATTCTTCTTCACGACGGAGCTGGACCATCACGTCCTGACCTTTCATCGTCCAGGGGAGAACCCTTCGCCGTCCGAGAACGCACGCGACACGAAGGATGCTGAGGCTGAGACGCGCAACTGCGACGGCAATGTAGCGGTGAAGGAGGAAGTGGTGCAGGttgacgaggaagaggaggaagaggaagaggaggaggaagaagtgAACGTGGACGTGGATCGGGTAGGACAGGAGAAACGCGAAAAGGGTGCCTCCGGACAAAATGAACAGAAACTGAAGACGGAAGTCGACAGCGAGACGACCAAAACAGAGTCGTGA
Protein Sequence: MLSLRFRLTNSFGYIQRFFSSDHLKIHMKTHDTQKPYQCTACSRGYNTAAALTSHMQSHKKHHQSSSQSTGGKLHDVDYGRRSVSSHSTSSPPVPSSPSPSLNLGLNPRPNALKTSQSTCSASTTPVLSSPLKLTCMYCTKDSFSCMQQLQMHVHSMHQAILSGESLVVPPSPSGTNEQITPGSRDKSLADRQVDGLSSKDSRDRKYPEDRERPGERDHYENAFTCNQCTMKFSTLGCLRDHLLSIHRLGAFGAAMMMCPLCGIPCSSAASYAEHYVLQHCENRRIAPTAAIEYGEPKVNGVYDGVTRDTRLQRSTDVQPEAADLTNKHSVRPTTTTTTITTTTTTTTTTTTTTNDAGGGGGYTAGTLLCGQCGAALKDFESFREHLARHLQADHRNEVSRHPCSKCEATFPDREDMLNHLIKHYLGQVSKEYACGACKKLYPHPDLLQRHLLDSHAHHLYRCALCRDTFDSRVAIQLHFAVKHSQECRVYRCSACCTLSNNENSPGNAPGEGRSFFRSEAEMAAHVRNVHAPPAALINSSPGLARSPASTPGITSGGAAARCVFCGVCCNSELELQLHLASHSASLYRCPVCKEGFAVEFLLDRHVAQAHAGDHRPASSSVRNRERERERERENGRVHRPVRNQEEPKSLKRGRSPASSNNNSLNQRDNNNKRPNFGTSGGQQCELCERGEFANEAELQAHKKLVHTPSKLPSSKSVSALSMTCAYCGEVCRSRSELESHTRIQHASNEPGGRHKCNICDEVCPSGATLAEHKLQKHCKIQLSDICVVCRGRLASESQFLEHVQRHSLENVDPQQRLDNSLPHLPAPCVICRQTLISDLECRLHARHHLRTSSGSHSDGSSPASPAAKAAQSPGCCFCLRDFAADDFVSLPPNHASAGGQPLRVCKSCYVRHSQGLPILNSTYEQRAKYEAAWLAQNKDAQWDSSHKDKWENGRGLKAEDRPRKERNADNNKRCEECGVKFEDPEEAEKHRIAEHREKVPFATEAKVQQHVRKEHLCDTSAKSSLEALRCHLCLFEAASPLQLQSHLIEHTFAGCPAFNCYICQALFTAPVGLQNHMVQEHGLGARPYDCSKCTLKFFFTTELDHHVLTFHRPGENPSPSENARDTKDAEAETRNCDGNVAVKEEVVQVDEEEEEEEEEEEEVNVDVDRVGQEKREKGASGQNEQKLKTEVDSETTKTES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00452758;
90% Identity: -
80% Identity: -