Hruf052732.1
Basic Information
- Insect
- Harpalus rufipes
- Gene Symbol
- lola
- Assembly
- GCA_951394225.1
- Location
- OX596288.1:1442915-1452646[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0021 0.46 12.9 0.5 1 21 10 30 10 31 0.95 2 14 0.00026 0.056 15.7 0.9 1 21 56 76 56 77 0.97 3 14 0.00016 0.034 16.4 1.7 1 21 109 129 109 130 0.97 4 14 4.6 1e+03 2.4 1.6 2 15 139 152 139 154 0.82 5 14 0.00073 0.16 14.3 1.3 1 21 164 184 164 185 0.97 6 14 5.9 1.3e+03 2.0 1.4 2 12 194 204 193 208 0.80 7 14 0.00031 0.067 15.5 0.8 1 21 221 241 221 242 0.97 8 14 7.3 1.6e+03 1.7 0.3 2 8 251 257 250 260 0.85 9 14 0.0012 0.26 13.6 0.6 1 21 274 294 274 295 0.97 10 14 4.2 9.1e+02 2.5 0.2 2 11 304 313 304 317 0.80 11 14 9.2e-05 0.02 17.2 0.6 1 21 330 350 330 351 0.97 12 14 3.8 8.4e+02 2.6 0.4 2 11 360 369 360 373 0.79 13 14 0.0027 0.6 12.5 0.9 1 21 391 411 391 412 0.96 14 14 0.086 19 7.8 3.6 2 23 421 443 421 443 0.91
Sequence Information
- Coding Sequence
- ATGTATCGCAGACTTTCTGAAAAAGTATTTGAATGTCTTCAATGTAAACGCCGATACACTACCAAAGGCTCTGTAGTGCGCCATCTTAAATTTGAATGTTCTAAGGAACCACAGTTTGTGTgtGAATGGCGTTATGTCCATGTGCAACAAAGGAAAAAACCCAAATTCCAATGTGCAAAATGCAATAACGCATacactttaaagaaaaatttaaacaggCACATACGATACGAATGTGGAAAACAACCTACAGCCCAGTGCCCTTATTGTCCCTATAAAAgtGGATGGCGTTATGTCAATGTTCCAAAAATGAGACAACCCGTATTCCAATGTACAAAATGTAATAACGTATACACTTTTAAGACAAGTTTAATGAGACACATACGATATGAATGTGGAAAAGAACCTACAGCCCAGTGCCCATATTGTCCTTATAAAAgtGATCGGCGATGCCATTACGTCGATGCTCCACAAACGGAAAAACCCAAATTCCAATGTGCAAAATGCAATTGCGCATACTCTTTAAAGGCAAGTTTAATGAGGCACATACGATATGAATGTGGTAAACAACCTACTACCCAGTGCCCTTATTGTCCTTATAAAAgtGTTCAGCGATGGTGTTATGACAATGTTCCAAGAGCACAAACTAAACAACCGAAATTCCAATGTGCAAAATGCAATAACGCATACACTTTAAAGGGAAATTTAAACAGGCACATACGGCACGAATGTGGAAAACAACCTACTGTCCAGTGCCCTTATTGTCCTTATAAAAgtGAATGGCGTTATGTCCATGTTCCACAAACGAAAAAACCCGAATTCCAATGTGCAAAATGCAATAACGCGTACACTTTAAGGAGAAATTTATTGAGGCACATACGATATGAATGTGGAAAACAACCTACAGCCCAGTGCCCTTATTGTCCTTATAAAAgtGATCAGCAATGGCGTTATGTCGATGTAGTACCACAAACGACAAAACCCAAATTTCAATGTGCAAAATGCAATAACGCATACACTTTAAAAGGAAATTTAACCAGGCACATGCGATATGAATGTGGAAAACAACCTACTGCCCAGTGCCCTTATTGCCCGTATAAAACTATCTACAGAGATAAAATACCGCGTGAATGGCGTTATGAACATGTTCCACAAACGAAACAATCCAAATTCCATTGTGCAAAATGCAATAACGCATACACATTAAAGGGAAATTTATCCAGGCACATACGATACCAATGTGGAAAACAACCAACTGAACAGTGTCCTTATTGTCCTtataaaactttttacaaaCATCATATTCAACagcatataatttttaaacacaggataagaattaatttgtaa
- Protein Sequence
- MYRRLSEKVFECLQCKRRYTTKGSVVRHLKFECSKEPQFVCEWRYVHVQQRKKPKFQCAKCNNAYTLKKNLNRHIRYECGKQPTAQCPYCPYKSGWRYVNVPKMRQPVFQCTKCNNVYTFKTSLMRHIRYECGKEPTAQCPYCPYKSDRRCHYVDAPQTEKPKFQCAKCNCAYSLKASLMRHIRYECGKQPTTQCPYCPYKSVQRWCYDNVPRAQTKQPKFQCAKCNNAYTLKGNLNRHIRHECGKQPTVQCPYCPYKSEWRYVHVPQTKKPEFQCAKCNNAYTLRRNLLRHIRYECGKQPTAQCPYCPYKSDQQWRYVDVVPQTTKPKFQCAKCNNAYTLKGNLTRHMRYECGKQPTAQCPYCPYKTIYRDKIPREWRYEHVPQTKQSKFHCAKCNNAYTLKGNLSRHIRYQCGKQPTEQCPYCPYKTFYKHHIQQHIIFKHRIRINL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00768975;
- 90% Identity
- iTF_00768975;
- 80% Identity
- iTF_00768975;