Hruf061422.1
Basic Information
- Insect
- Harpalus rufipes
- Gene Symbol
- topi
- Assembly
- GCA_951394225.1
- Location
- OX596291.1:21817473-21821772[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 2.9e-05 0.0062 18.7 4.8 1 23 155 177 155 177 0.98 2 15 7.7e-08 1.7e-05 26.8 0.5 1 23 183 206 183 206 0.97 3 15 0.035 7.6 9.0 0.2 1 23 212 234 212 234 0.97 4 15 4.4e-05 0.0096 18.2 0.8 1 23 240 262 240 262 0.96 5 15 1.1e-05 0.0023 20.1 1.8 1 23 268 290 268 290 0.98 6 15 1.1 2.4e+02 4.3 6.9 1 14 296 309 296 310 0.88 7 15 0.00016 0.034 16.4 0.3 2 21 404 423 403 424 0.93 8 15 0.041 9.1 8.8 0.8 1 23 435 459 435 459 0.94 9 15 0.0048 1 11.7 2.1 1 23 495 517 495 517 0.98 10 15 3.6e-05 0.0078 18.4 0.3 1 23 523 546 523 546 0.96 11 15 2.2e-05 0.0048 19.1 0.2 1 23 552 574 552 574 0.97 12 15 1.1e-06 0.00024 23.2 0.8 1 23 580 602 580 602 0.98 13 15 0.001 0.22 13.9 0.7 1 23 608 630 608 630 0.96 14 15 5.7e-06 0.0012 21.0 1.9 1 23 636 658 636 658 0.97 15 15 1.1e-05 0.0024 20.1 1.4 1 23 664 687 664 687 0.95
Sequence Information
- Coding Sequence
- ATGAGCGAAGAAAGTTTAACCTCAGTTGAAGAGCCAATCATCCAGCTGACGGAAAACGGCGCGGAAGGATTCGAAGTCCTATGTAGGCTTTGCGCGAACCGAAGCGACCATTTAATTCCGATCTACAGCGAAGAAGGCGTCTCGAATGATTTGGCGGATAAAATGAATATGTATCTGCCGGTGAAAATATCACGAATCGATGTGTTGCCACTTCAATGTTGCTTCCAGTGTGCGACGACAGTTTTAACGTGGCATGAACTCGTGGTCGCGAGTGTTGAGGCAGACAGGAGATTGAGGGAAGTACAAGCCGAAGTGGAAAAGCAAATTGTTGAGCAAGAAGAACCCGGCCCCTCGCAAACTGAAACTGTTGACGACGACAGGTGTGCACCGGGCTTAAATACCAACCAAACAACAATTAATTCCGACGAAACTGAATCAGACACATTAAAAATTCGCAAAACCTTTCAATGTGCACATTGTTCCaaaaatttctttcaaaaaaGTTCCCTCGAACGCCATTTTCGCATTCACAAAAACGAACGCCCGTTTACATGCGAAGTTTGCGGCAAAGGCTTCCGCGATAACAGCGCCCTAATACGCCATATCCGGCATGTGCATATCCGAACTAAAGACTTCCCGTGCGACATCTGTCGGGTGAAATTCGCATCGGCGGCGACGAGGGACGATCATCGCCGATCTCACACGAAAGAGTGTCCGTTTACGTGTCAAATTTGTGGGAAAAATTTTGGGAGGAAAGCTAGtttatatattcataataaattaCATGTAGATGTGTTTCCGTTCAAGTGTAGTGTGTGTGAAAAAAAGTTTCGCAGACGACAGGAATTGGTGAATCATGTGACGACGCATAGTGGTGAAAAGCAGTTTGCTTGTGAAAAGTGTGGAAAATGTTTTAGGAAATGCTCGAGTGACAATCTGAGCCCATGCCCCGGCACCCAGGACCTCAAAGAGGAGCCCGAGGTCGACCAGGAACCCAAACCAGAACCAGACACAGAACCACCCACTCGCAAACGTCGCCGCAAGGCCCTACAATTCCAATCAACCGACGGCGAATGGATCAAAACTGAATTCATCCTTAGCTCAGATTCATTCGAAATTGAGGCAGACGTTAAGTTAGACCCTCTCCACGTTCCGGGACAGGACGATTCAGACGAAGAATTTGCAGAAATCAATCAAGAATCGTTGTTAAATTGCAATAATTGTGATCAAGTTTTTACGAAGCCTGTTTTgttgaaaaaacatttaaaaaattgtgcCAACAAGAATGTTAAAAAGAGGGAATATCGGTGTGATTTTTGTAGTTTTGTGACGGTGAAAAACAAAGAAGACTTGAAAAAACATATAGAAAGTGACCATCCGGAACATTATACAAcatttactgaaaaaaaaatcaaaaaacgaAGCAAGATCGACCAAGACGCCGTCAATCGCGCAAAAGTTGTCGTGGAATCAAGAACATACTATCATTGTGATATTTGCGGGAAAAATCTTCATTCTCCATACACATACATCTGGCATAATCGTATTCACACTGGAGAGCGaccatttatttgtgatttatgCGGCAAACAATTCCGCGTTTCTCAAGGTCTCGTCCGCCATCTTCGCGAAACACACGCCGGCATTAAAAACTTCGCTTGTGACCTCTGCGGAAGAATGTTCGCAACCAGACGCAACGTGGAAGAACACAGACGAATCCACACGAACGAACGGCCGTATATTTGCGACCTGTGCGGCAAAAGCTTCAAACAAAAAGCTTCGCTGTTTGTTCACAATCGATCGCATACGGATTCATTCCCGTTCAAATGTTCGTATTGTAATCAGGGATTCAGAACTCGGCCGCCATTGTTGGTACATGAAACGAGGCACACCGGCGAGAAACCTTACGCGTGTGATGTATGCGGGAGGTGCTTCCGGATTAAATACGAGCTTAAAAGACATCGGTTGATTCATTCGGATGAGAAACCGTTCAGTTGTGAAGATTGTGGAGTTAGTTTTAGGCAGAAAAGATATTTGAGGAAtcataataaaattaaccaTAATAGGGCTACGCCCTGA
- Protein Sequence
- MSEESLTSVEEPIIQLTENGAEGFEVLCRLCANRSDHLIPIYSEEGVSNDLADKMNMYLPVKISRIDVLPLQCCFQCATTVLTWHELVVASVEADRRLREVQAEVEKQIVEQEEPGPSQTETVDDDRCAPGLNTNQTTINSDETESDTLKIRKTFQCAHCSKNFFQKSSLERHFRIHKNERPFTCEVCGKGFRDNSALIRHIRHVHIRTKDFPCDICRVKFASAATRDDHRRSHTKECPFTCQICGKNFGRKASLYIHNKLHVDVFPFKCSVCEKKFRRRQELVNHVTTHSGEKQFACEKCGKCFRKCSSDNLSPCPGTQDLKEEPEVDQEPKPEPDTEPPTRKRRRKALQFQSTDGEWIKTEFILSSDSFEIEADVKLDPLHVPGQDDSDEEFAEINQESLLNCNNCDQVFTKPVLLKKHLKNCANKNVKKREYRCDFCSFVTVKNKEDLKKHIESDHPEHYTTFTEKKIKKRSKIDQDAVNRAKVVVESRTYYHCDICGKNLHSPYTYIWHNRIHTGERPFICDLCGKQFRVSQGLVRHLRETHAGIKNFACDLCGRMFATRRNVEEHRRIHTNERPYICDLCGKSFKQKASLFVHNRSHTDSFPFKCSYCNQGFRTRPPLLVHETRHTGEKPYACDVCGRCFRIKYELKRHRLIHSDEKPFSCEDCGVSFRQKRYLRNHNKINHNRATP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -