Hrub030355.1
Basic Information
- Insect
- Harpalus rubripes
- Gene Symbol
- YTHDC2
- Assembly
- GCA_963082715.1
- Location
- OY720453.1:27601693-27615125[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.025 6.4 9.7 0.3 2 23 1766 1787 1765 1787 0.96 2 10 0.00059 0.15 14.8 2.2 1 23 1794 1816 1794 1816 0.98 3 10 0.0022 0.55 13.1 3.3 1 23 1856 1878 1856 1878 0.97 4 10 0.0035 0.89 12.4 4.5 1 23 1883 1907 1883 1907 0.96 5 10 0.00015 0.037 16.7 0.2 1 23 1913 1935 1913 1935 0.95 6 10 4.8e-05 0.012 18.2 1.6 1 23 1941 1963 1941 1964 0.94 7 10 0.00085 0.21 14.3 1.3 1 23 1969 1991 1969 1991 0.97 8 10 0.0032 0.81 12.5 1.7 1 23 1997 2019 1997 2019 0.98 9 10 0.0025 0.64 12.8 11.6 1 23 2025 2047 2025 2047 0.98 10 10 0.0015 0.37 13.6 1.1 1 23 2053 2078 2053 2078 0.97
Sequence Information
- Coding Sequence
- ATGGCATCACGAAAAAACAGAAAGAAGATTAAAGTTAGTGAAGATTTTAGTATTCGCACTGAATTAATATTAAGAAAGTTTATTTCTGATGATAGTTTAACAACTTACGAGTTTCCTAATACATTAACTAATGCGGAACGTGCATGGGTACATGATTTTGTTAAATCGTACTCACTGTCTTCTAGATCGTACGGTAAAGAACCGAATCGTAAATTGAGAATCATGAAACGTAACATTATGACAAACATAGACGTAGCTTCTATCAATTTAAGTAAAGAGAGTACACAACTAATTCAATCATTCTTGTGTAAGTTTCCTCTCGGTAAAGAAAAGCCTGAAGGAATTAATTTTGTGCGTCAGAAAAATACCGAAGGTTCAGCCAGTAGCATGGGACAGTTAAGTTTCGGGATTCCGCAGCTACCAACATTTAGCTTAAATAATCAGTTACTAAGTTTTCGAATGAACCTACCAATTTGGAATATGCGAGATGAAATCATGGAGCGTATTATCAGTAATCAAGTATTAATAATTCGAGGAGAAACTGGATCAGGCAAAACTACGCAAATTCCACAATTCATACTGGACTACAGTACTTCGTGCCAAGAGAAATGTCGAATCATTTGCACACAACCACGAAGAATATCCGCAATTTCAGTTGCGGAAAGAGTTGCTGACGAACGAGGAGAGAAAACTGGTCAAACAGTTGGGTATCACATCAGATTAGAATCATGTGTTGGACCGAAGACAACACTTATATATTGCACTAATGGCATCTTACTACGTACTTTGATGAACGGGGATTCTAGTTTAAATTCATACACTCATATTATTGTAGATGAAATTCACGAGAGGGATAGATTTTCTGATTTCTTATTAATTTGTTTGCGGGAATGTTTGGTGAAATATCCTAAAATAAGATTGATTTTAATGTCTGCGACGATTGACgtaaaaacttttcaaaactatttcaatGATCCGCCAGTTATCCATATACCAGGTCGTGTATATCAGGTTTTCACTTATTATTTGGATGAAATTATATctacattaaattatgaatctGCTGCAATGAAGGTTGCAAAAGGCAAGGTAGTTATTGCTCCTAAACCCAAAGTAGAAAACCCTCCACAGCGAGAGGAAGTAGAAAACTCAGATCTTCGTGCGGAGTTGGATGAATGCATTAATGAATATTTCACAACTGGCgttgaagatatttttaacgtatttttacaattcatattaaatgaacacGTTCCAGTAAACTATCAACATTCTGAGTCTGGGTATACAGCTCTTATGGCTGCTGCTGTTCATGGACACTTCGACATTTGTACACAATTATTGTATTTTGGAGCTAATGTAAAGATTCGATCAAGCCATGAGAATCTATCCGCAGCTGATTGGGCATTTGCTAAACAGCATATCCACATTTATGAAATGCTTAAGGAGTATGAACAACGAGATGTTCGCAACGCACTGAACTCGACTGGCATGTACCTTGAAGATGAAGCTAGAATGAAGTTAGAATTATATCAGCAAACAATTTACGATCAGAACATTGACTatgatttattaattcatttattatgcAGTATACACACTACTTCTGGACCGGGTAGTATTTTAATCTTCTTAGCTGGGTACGATGATATTGTGACCGTTCGCGAAAGGATCATGAACGACGGAAGATTTAGATTAACTCCGTTTGAAATATTCGCTTTGCATGGAATGATGCAAATGAGCGACCAACATAGGGTATTTAAATCTACAGGAGATTcaaggaaaattattttatcgACTAATATCGCTGAAACTAGCATAACTATTGACGATGTTGTATATGTAATAGATTGTGGAAAAGTTAAAGAAAAGACATACGATGCTATGACCGGAATTTGTAGTCTGCAATGTTGTTGGATTTCTCAGTCTGCAGCTAAACAGCGAGCTGGAAGGGCAGGACGAACTAAAGCTGGATTTTGTTTCCATTTATTTTCCAGGAATAGGTATGAATCTATGCAATCGTATACAACACCCGAAATGTTGCGTATGCCTTTACATGAGTTATGTTTGCAAACCAAACTTCTAGCTCCCAAAGACGTAAAGATCGCTCATTTTCTTTGCCGAGCATTAGAGCCGCCATCCACAATGGCTGTGAATCAAGCGATTAAGCATCTGCAAGAAATTGGTGCGCTAGATAAATATGAAAATCTTACAATCCTAGGACAACATCTGGTGGATTTACCCGTAGAACCCCGTCTTGCCAAGATGCTCATCTACTCTGTGATATTTAGATGTGTAGATCCTATTCTTACTATCGTTGCCTTCCTTAGCTATAGgGATCCATTTATGTTGCCAAATTCTCCCCAACACAAAGCTCTCGCTCTGGCTACGAAAAAGCAATATTCATCGAATACATTCAGCGACCATATGATTCTGTTAAAAGTTTTTCAAGCATGGCAGGATGCCCGACTCGCGTCAGAAGAACGTCTTTTCTGCACTAAAAATTTCATAAGTTCAGCAACCATGGAAATGGCTGTTAAGATTCGGTCCCAACTCTTAGCTCAACTTCGCGCCGGTGGTTTTGTCAATACTAAACCTCCAGGAGATATTAGAGAACTCaatgaaaattcaaataattggGCGATGATTAAAGGTATTTTAACTGCTGGATTTTTGCCTAACATTGCATTCTTAGATAAAAACCAAATGAAACTTCGAactaagaaagaaaaaaaagttgctataagtattttgtcttgtttacGATCGGGGGAAAAAAATAACAACGCAGATAATATTCagagtttaaaaaatattcctaCTGATTGGTTAATATTCGAAGAATTGTCTCGTAATAATGCCCTGTACAACATCAAATCTGTAACTTGTGTTACTTCCATTGCTGTTGCTCTTTTCTCGAATGATACCATTCCTCAAGTCGAATCTGATGAAACTGATTCGGATGATGAAGCAAGTCCGAAACATTGGATTATTTTTGACGAGTCAAATCCTGCAATGAATATTATTCAGGATTTGCGCAGTAAAATGAATTCTTTAATCGAAAAAAAGATTACAAATCCTCATAGATTATTCTCGTGCCACGACAGTTCGCTCTTACAGACAGTGTCATCTGTACTTTTAAAAGAAGACGAAGTGGTTGGGTTACACCAACCAGCTGGTATCGGACAACGGCCTAAAATCATGAATTGTAACAACGGCTGTAACCAGGAAGAATCTCCTCAGAATAGATTCAGGATGCAACAGCGTCCTCGAAAAAACGAAGAATGTTTGTATCAAGTGTTAACATTCAAGAAATTTAATCCTcgtttgtactgtaaatttgtCCCGCCACAATTTAATATTCCTGATGATGACGCTAATACGTCGAATGTCGCATCTGATCTAGAAATGGGTAGTCTCGTAAAAAAGTTTGAAGAGTTTAGTGTACAGAAATCGCCGCATGAACATACTTTACAAAATAGTAGTCTGTTtgaagaggatgattttggaCAAAATGGAATTAATGTTGAATTAGAAGGAGCTTGTTCTTTAGAACCAGTGTACAAACCTCTTTGGATGGATCAAGTTATGAACCCAGAATGGACGGTTTATTGTATGATACGAACAGGAACTGCAAGAAGTATCGACGTTTCCATTGGGAAGAAAGTTTGGGTGTTCCCTCCTTATATTGAGAAGagattgaaaatgatttttgaaactggaaaaaacattttattggtCTTCACCGTTATAAATTCTCGCTCCTTCCAAGCAATTGCCCGGCTAGTAAAAATGCCAGCCATAGAAGAAAGTGAATACAATATTCAGAGTTCATTAGAATGGATCAGCAGAGCAGATATATCTTTTGAACATGTACAAGAGTTTTTCCCGGATCAATACAACGATGGAGATCAACTGAACCATATATTTGGTGTGAAACTTTGGCAGCTATTTACTAACTTTGCCCCACCGAGTATTCAGCAGCTAGAACCGATGTTTGTCGTAGGAGgGACTACAGAAACTATCAACTTGTTGGTAGAAAAAAGGATTGCAAAAGATGCAATCTTTAAACAAACGAATTCTGATAGGTTAGGTTGGTTACAAGTTGTAGCAGATATGAAGAAAGAAGGAGGTTCATTGTTGCTAAATAGAATTAATGTACGGAAACAATGGTTTAAAATTTGCGAGTTTTATAagGTAACATTAGAAAAACAAACAGAAGAAAACATGAAGCAACAATTGTCTGAAACACCTTATTTTGCTAAgttaaaaaagttttttgataaaaatatagtGCAATCACACAAATCAAAGAATTTGAATCAAGggACTGTGGAGAAAACAGACGCATTAATCGATTCAAGAATAGCTCGATATTCTATGTTCAAGGGTAGAGGATATGCTGCAAATGCTTggaaGGCAATAGCACTAGACGTAGCTGAAATTGAACCGTCAGATTCCACTATGTCTGTTGCTCAAGTTAAGAAAAAATGGGAAAACTTACTCACTAAATATAGAAAGATACTACAGTCAAAAATTTATACCAACTGGCCGCATTTCTCAAAGATGAATTATTTCTATAATGAAATCTATAATGGAAGTGAAGAAAATGATACTGTTGATGTAAATTCTTCTGAAAAAGTAGAAAATGAAATTTCTGCCATTCCTGTTGCGAGTGctgataaatGGCCTCCCGATagaacatatttacttataaacaGAAGAATTGCCAGGGATTCTATGTTTGGTCGGGGAACATCAACCAAAGGATGGCAagCTGTATTGGATGATCTTATACTTGGTGGTGCTCCTAAAGATTTAACGATAGCTAACGTAAAGAAAAAATGGGAAAATCTACTTACGAGAcacaaagTAAAAATAGAAGATTTATTATTCAAAGAATTAGATGAAGAAAATGTAGACGAACCAGATTCTATAATAGATTACGAAAAGTTGAACAAATGCAGATTATGTCAGCAAACTAAAGGAGATTGCTCTTTAACAGAAGATAAATACCTTTGTGACCAAATTCTGAAATGTACTTCAATAAATGTTTGCGAAAATATAGACTTATTTCCATCATCAATCTGTGAATCTTGTAAAACATCGATAGAAAACTTTCACAAATTTCTTTTGATGTGTGAAGATGTTAACAAAGATTTAAAATCTTGTATAGAGCAAcctggtaaaataaaaatagaaaatagcgaagaaaatattttagaatcgCCTGCAGAAGATAGTGAAAATAATCTAGACGAAGTTGTAATAGATGTGCAAGATACGAAAACTTTAGAATGTCCAGAATGCCCTGCGTCTTTCACATGTGCAGAAACTTTTGAGACTCATCTGAAcagtcataaaaataataatacaaaatttcattgCGATATTTGTAGCATGGAATTTATCAAACAATCCAGTTTGTTTGAGCACATAAAGCGTCATTTTGAAATAAGTAACATTGAAACCGCAGACATTGATATGGAAGACGTAGAAATAGAATTTCTAGACGAAGATTATAATGAAGTAGATGCCAATGTTATTGTAGAACCTGAGGAATTATTTCATTGCGAATTGTgttcaaaaacttttatttcttCTACAAGTTTGAAGGAACATTTTGATACACATTCTAGAATAGAACATCATTGTCCAAGAGAAGATTGCAACAAGAAATTTACTTCATTAAACTCGTTACGTCAACATGAAATGAGACATTTAGGATTAAATTCTTTTCTGTGTACTGTTTGTGGGAAAGGTTTCGTGACGAGCAACGCTCTAAAAATGCATGAAAAAATACACGCGGCAGTAAAAGAACACATTTGTGAGATTTGTTCTCGAGGATTTGCTGTTGCGAGTAATTTGAAAGCTCATCAGAAGAAACACCATGAGGGACATCGATTTTATTGCTCACAATGTCCAAAACAATTCCTTACTAAAAGTAGTCTACAAAGGCATGAGTTGGTTCATACAGGTGTTAAAGAATTTGTGTGCGATATTTGCAGTTCTGCATTTTTTACTCTTAAAGAACTGAAGAAACATAAGCGCTATCACGAAgGCATCAGACTATATCATTGTCATGAatgttataaaacatttttcgaGAAACATCATTTAACAATCCATATGCGAACTCATACGGGAGAACGGCCATACGAATGTAAAATTACAGGATGTAAAAAGGCATATAAAGAAAAGCAGAAACTGAATCGGCATGAGAAAACTgcacatttttgtaaataa
- Protein Sequence
- MASRKNRKKIKVSEDFSIRTELILRKFISDDSLTTYEFPNTLTNAERAWVHDFVKSYSLSSRSYGKEPNRKLRIMKRNIMTNIDVASINLSKESTQLIQSFLCKFPLGKEKPEGINFVRQKNTEGSASSMGQLSFGIPQLPTFSLNNQLLSFRMNLPIWNMRDEIMERIISNQVLIIRGETGSGKTTQIPQFILDYSTSCQEKCRIICTQPRRISAISVAERVADERGEKTGQTVGYHIRLESCVGPKTTLIYCTNGILLRTLMNGDSSLNSYTHIIVDEIHERDRFSDFLLICLRECLVKYPKIRLILMSATIDVKTFQNYFNDPPVIHIPGRVYQVFTYYLDEIISTLNYESAAMKVAKGKVVIAPKPKVENPPQREEVENSDLRAELDECINEYFTTGVEDIFNVFLQFILNEHVPVNYQHSESGYTALMAAAVHGHFDICTQLLYFGANVKIRSSHENLSAADWAFAKQHIHIYEMLKEYEQRDVRNALNSTGMYLEDEARMKLELYQQTIYDQNIDYDLLIHLLCSIHTTSGPGSILIFLAGYDDIVTVRERIMNDGRFRLTPFEIFALHGMMQMSDQHRVFKSTGDSRKIILSTNIAETSITIDDVVYVIDCGKVKEKTYDAMTGICSLQCCWISQSAAKQRAGRAGRTKAGFCFHLFSRNRYESMQSYTTPEMLRMPLHELCLQTKLLAPKDVKIAHFLCRALEPPSTMAVNQAIKHLQEIGALDKYENLTILGQHLVDLPVEPRLAKMLIYSVIFRCVDPILTIVAFLSYRDPFMLPNSPQHKALALATKKQYSSNTFSDHMILLKVFQAWQDARLASEERLFCTKNFISSATMEMAVKIRSQLLAQLRAGGFVNTKPPGDIRELNENSNNWAMIKGILTAGFLPNIAFLDKNQMKLRTKKEKKVAISILSCLRSGEKNNNADNIQSLKNIPTDWLIFEELSRNNALYNIKSVTCVTSIAVALFSNDTIPQVESDETDSDDEASPKHWIIFDESNPAMNIIQDLRSKMNSLIEKKITNPHRLFSCHDSSLLQTVSSVLLKEDEVVGLHQPAGIGQRPKIMNCNNGCNQEESPQNRFRMQQRPRKNEECLYQVLTFKKFNPRLYCKFVPPQFNIPDDDANTSNVASDLEMGSLVKKFEEFSVQKSPHEHTLQNSSLFEEDDFGQNGINVELEGACSLEPVYKPLWMDQVMNPEWTVYCMIRTGTARSIDVSIGKKVWVFPPYIEKRLKMIFETGKNILLVFTVINSRSFQAIARLVKMPAIEESEYNIQSSLEWISRADISFEHVQEFFPDQYNDGDQLNHIFGVKLWQLFTNFAPPSIQQLEPMFVVGGTTETINLLVEKRIAKDAIFKQTNSDRLGWLQVVADMKKEGGSLLLNRINVRKQWFKICEFYKVTLEKQTEENMKQQLSETPYFAKLKKFFDKNIVQSHKSKNLNQGTVEKTDALIDSRIARYSMFKGRGYAANAWKAIALDVAEIEPSDSTMSVAQVKKKWENLLTKYRKILQSKIYTNWPHFSKMNYFYNEIYNGSEENDTVDVNSSEKVENEISAIPVASADKWPPDRTYLLINRRIARDSMFGRGTSTKGWQAVLDDLILGGAPKDLTIANVKKKWENLLTRHKVKIEDLLFKELDEENVDEPDSIIDYEKLNKCRLCQQTKGDCSLTEDKYLCDQILKCTSINVCENIDLFPSSICESCKTSIENFHKFLLMCEDVNKDLKSCIEQPGKIKIENSEENILESPAEDSENNLDEVVIDVQDTKTLECPECPASFTCAETFETHLNSHKNNNTKFHCDICSMEFIKQSSLFEHIKRHFEISNIETADIDMEDVEIEFLDEDYNEVDANVIVEPEELFHCELCSKTFISSTSLKEHFDTHSRIEHHCPREDCNKKFTSLNSLRQHEMRHLGLNSFLCTVCGKGFVTSNALKMHEKIHAAVKEHICEICSRGFAVASNLKAHQKKHHEGHRFYCSQCPKQFLTKSSLQRHELVHTGVKEFVCDICSSAFFTLKELKKHKRYHEGIRLYHCHECYKTFFEKHHLTIHMRTHTGERPYECKITGCKKAYKEKQKLNRHEKTAHFCK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00769256;
- 90% Identity
- -
- 80% Identity
- -