Hrub046310.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Harpalus rubripes
Gene Symbol
ZFHX3
Assembly
GCA_963082715.1
Location
OY720456.1:54695240-54720060[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.00043 0.11 15.3 1.8 2 23 337 359 336 359 0.95
2 18 0.00011 0.027 17.2 0.7 1 23 391 415 391 415 0.92
3 18 0.016 4 10.3 0.4 1 22 458 479 458 482 0.91
4 18 3.3 8.4e+02 3.0 0.3 1 23 861 884 861 884 0.82
5 18 0.0013 0.34 13.7 0.2 1 23 912 935 912 935 0.96
6 18 5 1.3e+03 2.5 3.0 2 21 1021 1040 1021 1044 0.87
7 18 0.34 87 6.1 0.4 1 23 1056 1081 1056 1081 0.91
8 18 0.0073 1.9 11.4 1.6 1 23 1099 1121 1099 1121 0.97
9 18 0.0021 0.52 13.1 0.6 2 23 1128 1150 1127 1150 0.96
10 18 0.00042 0.11 15.3 3.1 1 23 1263 1287 1263 1287 0.92
11 18 0.012 3.2 10.7 0.6 1 22 1307 1328 1307 1331 0.89
12 18 0.0017 0.44 13.4 0.2 1 23 1387 1411 1387 1411 0.93
13 18 0.0065 1.6 11.6 0.1 3 21 1493 1511 1493 1512 0.96
14 18 0.68 1.7e+02 5.2 2.4 2 19 1634 1651 1633 1656 0.90
15 18 0.00027 0.067 15.9 2.5 1 23 2221 2243 2221 2243 0.99
16 18 0.0012 0.29 13.9 0.3 1 23 2336 2358 2336 2358 0.98
17 18 0.015 3.7 10.4 0.4 2 23 2511 2533 2510 2533 0.96
18 18 1.1 2.7e+02 4.6 2.5 3 23 2790 2812 2789 2812 0.90

Sequence Information

Coding Sequence
ATGCCCACTCTGTCCGCGGCGCCTGAGCTGAGTCCCGGCGGCCGCACAGAGCGGCACAAGCTAGAGCTGTCCGCAGACATGAGCCCCGAGCAAGAGGCCAGTCCACCGCCCGCGGCTCCGGGAGCGTCGCCGCCGCCGCAGCCCACGCGCCTCCCGCCCTCGCCCGCCGCCTCCCACACCTCGCACGCTTCCCACCACGACACCACCTCCGACGTCGAGCAGTTCTCCGGCAAGATCGTCTACAACCCTGACGGCAGCGCCTACATCATCGAGGACAGCGAGAGCGAAAGCGAGACCACCGGGCCAGTGCTGCCCGAGGTCGTGCCGCCACTACAAGCCGTCTACGTCTCCAGGCTGCTCAGTAGGCATCAGACCGCCAGGCAACAGCAAGAACCCGCGGCCGTGCACAGTTATAGGGTGGTAGCGTTGAGAGATGCGCGCCCACCCCGACCAGCCAGCGTACCCGTTAAACCCATCCTCATGTGTTTTGTGTGTAAGCTGTCGTTCGGGTTCGCGCGGTCGTTCGCGGGACACGCGCAGGCCGAGCACGGTGTCACGCTGGCGGAGGCGGAGCGCGAAGTTCTGGCGGCCGACTGCAGCGCGATCTTGCAATGCGTGGGTGCGGACAAGCGGCCGATGGTGTCGTTGTTGGAACCCCTAGGCCCCGCAGCACCACCTGCCCACCAGGACATGATGCAAGGCCAACAACCGATGGATGCGACGCGGGCGGACCGCTCCTCGCCCGAGCACCAGCACCATCAGCAGCACCTCGCCATGCAGCAACACCAGCTTCAGCAGCAGCGTCTAACCCCAGGCAAGTCTCCTTCCCCGCCCTTCGCCGCGCCGCCCGCCTTCATGACCGGCACCACGATAGGCGTGTGTCCCGAGCACTTACAGGGTCGGCCTTCGGGCGCCGATTGCCCGCGTTGCGAGCTCATCCTCGCGTCCGGTCGCCTCGGACCCGCTGGCCTCGGCAACGTGCACAGTCGCAACTCCTGCAAGACGCTCAAGTGCCCCAAGTGCAACTGGCATTACAAGTACCAAGAGACCCTTGAAATCCATATGAAAGAGAAACATCCGGAAGCCGAGACGAGTTGTATATATTGCATAGCAGGGCAGCCGCATCCTCGCTTAGCAAGAGGGGAAACTTACACTTGCGGTTACAAGCCCTACCGATGCGAAGTTTGTAATTACTCTACAACGACGAAAGGGAACCTGAGCATACACATGCAGTCTGACAAACATCTCAACAACATGCAGGAATTACAAAACGGCGGCGCGCCTTCAGCCGTCGAAAGCCGGCAAGCATCACCAAAAGCCCCACCTATGCACCACTCACCTGTCAGCAGTGGCCATAAACCTAAACCTAGTTTTCGTTGCGACGTGTGTAACTACGAAACAAATGTCGCTCGTAACTTACGCATTCACATGACGAGCGAAAAGCACACGCACAACATGCTTGTGTTACAACAAAACGTCAAACACATGCAGACATTATCCGCATTACATCATCAACAACAACAACACTCTCAGCAACAACACTTGGAGAGTTTATTCGGCGCAGCGGCTGCGGCAGGACACGCAGGTTTATACCCAGGTTTAGGGGATAAACCTGAAGCTGCTTTGGCAGACATGGCCTACAACCAGGCATTGCTTATCCAGATGATGACGGGTGGGCAATTACCTGGTCATGGTGGACCGGCAGATTTGGCACCGCACGCCGATTTAGGATTGAATCCTGACACTATGGAACCTCCGCCTGAACCGGCGGACCCCGACCCGGAAAAAACTTATCAATGTTGCGTTTGTAATGTTTTCAACAGTGATTCTTTAGATGAGTTAGGTCGGCATTTAGCCCAAGACAGAACGAGATTAAGAGAGCAAGAAATTTTAGCAGTTGTGGCTGGACATTATGTGTGCAAACTTTGCACTTACAAAACTAACCTAAAAGCAAACTTTCAACTTCATTGCAAAACAGATAAACATCTTCAGAGGTTACAGCATGTTAACCATGTGAAAGAAGGTGGGGTCAGAAATGAATGGAAGCTAAAATATGCCTCGGCCCCTGGTGGAGTTCAAGTGCGATGCAACGCTTGCGATTACTACACCAACTCTGCCCACAAACTGCAGCTTCATGCAGCGGGTGCAAGGCATGAAGCCGGTGCAGCTCTTTTGGCACATCTTGCCGAAAGATGTCGGCAACTGCGACCGGACCAACCGAGAGTGTTCCACTGTGCATTGTGTGGTTTTACAGCCCCTGCGAGATTACCACTCCTTCAGCATGTGAGAAGCTTGAAGCACTTGCACCTGGAGCAATTGCATCAGCTGCAGAGACGCGCTGAAGGGAAGGATGCGACGCCGGAAGTTGGGGAGGTGTTTCAAGTGATAAGTCAGCCTTTGCCGCCGAGTACACCCACCGAACAGCATTCGCCAGTCGACCGTAAAGAACTAGTTCAACCGGACGTCAAAATGACCCCCGAGTCCATGAAAGACCAGTTCAAATACGAGCCGCGCGATGACAGCAGCGAAGACGTCGGTGGTGGCGGCGGAGCGCCGGGTGGTGAAGCCACCACTCCACAACACGCGTGCCCGTATTGCAACTACACCAGCAACTCGGAGATGCGGATCCAAGCACACGTGCTCGCACAGCATGGTGCGCAAGCCAGCACGCCTGGACCCCAACCAGACACCCCTAGCACAACTCCCACCAACCCCGGCGCGCACGGGCACTGCTTCCAGTGTCCTCTTTGCCAGGACTCCTTCAAGGACCGGCCGAGCCTTGAACGCCATGTCATGCAGATACACTCGGTCAACTCGGAGGGACTTCAAAGACTGCTTATGCTTGTAGACCAAAGCCATTGGCTGAACCAGGTGTCGCGGACATCCACGCCTAGCCAAACTCCCAACGCGCAACATACCCCGCCGAACCAACTCGTCTCGCCTAGCTCTGTCTCCTCAAAAGACTCTGTCAAGCTGGAGAAACAGGACGGCAACAACGTTGATCTCGAACCTGACTTAATGTCGCCAAATAGTGAGGAAATTTCTGAATATGAAACTGAAAGATGCTCCACGTGCTTCAAAAACTTCCGCAACATCGACGAATTGTGCTTCCACCAAAATGAAACCGGCCACCTGGAGATTAAACAAACGCCTAGCGGACCGGGTTATGTGTGCTGGAAAAAAGGCTGTAATCAATATTTTCCTACTGCACAAACGTTGCAGATGCATTTCAAAGACGTGCACGCCAAGAACTCTGTTTCACAAATGTCAGTGTCTGAAAAACATGTGTACAAATATAGATGTAATCAATGCTCATTAGCCTTCAAAACTTTAGAAAAACTACAATTACATTCGCAATATCACCTTATCCGAGATGCAACAAAATGCGTTTTATGTGGACGGAGTTTTCGTTCTGTAGTTGCATTACACAAACACGTGGAGACCGTACATTCAGAACTTACTGACGAAGAGCTTGCAGCTTACAAACAAAGCCTCATGAATAACCCTTTATTGTTAGCCGGTCTGCAAGGCCAAGTACTGGATAGCTCCACCAATGAGCTACTAAAGAAAGAATCGATGCGTGACGACAATATGCTGGACGCTTCACCTGGTGAAGGCGACGACGCAAAAGACGTGAGCGGTGCTACAGATGCCAGTGATGCTAATCAGACCATGGATGGTGATAATTCCGACGATAGCATTGTTTACAAAGACCAACAGTTCCTAGAAGATTACCTGAACAGCCAGGCGATAGCCGAAGACAGTTACAACGATCCGAATAGAAAATACAAGTGCCATCGGTGCAAGGTGGCCTTCACGAGACAAAGCTACCTGACCGCCCACAACAAAACCCTTTTACATAGAAAGGGCGAGAAACTAAGCTATCCTATGGAGAAATACCTGGATCCGAACCGCCCATACAAATGCGATGTGTGCAAAGAGAGTTTTACGCAGAAAAACATTCTGCTCGTTCATTACAACTCAGTCTCTCACTTGCATAAACTCAAGCGCGCCATGCAAGAACAGCAGCAACAGAACAACAACAACAATCCAGCCGTGTCACCAGTGTTACAACAGCCCACTGCCGCTGCCGTAGCTCTCGCCACCGGCCAAACACGCGGAGGTGCTGGCTCTCCTGATGAAGACGACAAGAAGAGATACAAGTGCAACATCTGTAAGGTCGCCTACACCCAGGGCAGCACGCTAGATATTCACATGAGAAGTGTGCTACATCAGACAAGAGCGAGTAAACTTCAAGATTTGGCAATGGCTGGTCAAATAGATCTGACGAAGCCTCTGATAGAGCAGCCGGAGTCGATGTCCGCCGTGCAGTCTCCGAAGCAGCCAGCGGGAGCACCCTTGCAGCCGAGTCCCAGCCCCGGCCCTGGACAAGGGGCGGGAGGGGATAAACGTTCCCCCACCCCTGCTAGTCCCGGGCCAGGGCCCGCTACCTGCCAGCAGCAAGGGATGCTTGGATGCCCCAAGTGCGGCGCGTTATTCAGCACGCAAGAACAGTTGAGCGCACACCAGCAGCTGTACTGCATGTTCGCCGCTCCGATGGCAATCTTCCAGCAAGGCCAGGAGCCCGGACAGGCGAAGAGCCCGCCGCCCAGTGACCAGGACCTCGCTGCGAGACTCAACCTCCCCAGGAAGACTGGTTCGCATATGTACAAACACCTATTAGAAAGTTTTGGTTTCGACCTTGTGATGCAATTTAACGAAAATCACCAACGACGTCAACGAGAAGAACAACAGCGTGCTGCCACACGGACACCTACACCGCCAGTAGCAGCACCTCCAGCTCCTTTACCAGTCGAAGAACCAGTAGCACCTCCCCAAGATGTCACACGTTTGGAAGAAGAACCTGAACTTAACAACCTTCCAGAGGTTCACAAATCTACATGTCAACATTGCAACAAAGAATTTTCCAGTGTTTGGGTGTTAAAATCTCATTGTGAAGAAATTCATAAAGACTTAGTGCCATTAgagtttttagaaaaatacgcGCAACAATTTAAAAACGAGTATGAAAAGAAATCCGTTGTTGTCACCGCTGCAACGAGTTCAACTTTATCTACAACTCCTCGAGTAAGTACACCTGGTGCTCCAACCACGACCACGCCTTCAGCTGAAGCTAGCACGCCTGAAAAAGAAGACGACAAGGAAGCGCTCCACGCCAAACTTAACCTCACTACTGAGGCTAATTCAACAGCTCCTTCAACGCCTACTTCGAGCGGGACTCCTGTTAGTGGTACGGAGTCCGTTCCAGCGAACATCCAAGCTATTCTGGCTCAAAGTATGGCGCAGAATCCCATGGCGTTAGCGCAACAGATGAGCGAGATGCAGGCGGCCTTGAACGTGATGCAACTTCAGCAGCTGAATTTCAACCCCATGATGCAAATGATGGGGATGGGATTGCCTCTAGGGTTGAACGCTCTGGCGGCCATGAACTTGCAGCCGCCTTTGGTGCCGCTGATGATGCCTCCGCCCCCGTACGCGGACCCCATAGGGCAATTTGGGCCCCAGGATCAACAAGCGATGATGGCCAAACAGCAGCAGGCGCTTTTGCAGCAGCAACAAGCGGCAGCAAATGCAGCAGCAAATCAGAAGCGCGCCCGGACGCGCATTACCGACGACCAGCTGAAGATCCTGCGAGCGCATTTCGACATCAACAACAGTCCGAGCGAAGAACAAATTCACGAGATGGCCGGCCAAAGTGGCCTTCCACCCAAGGTCATCAAACACTGGTTTCGCAACACACTTTTCAAGGAGCGACAGAGAAACAAAGACAGTCCTTACAATTTCAACAACCCGCCAAGCACGACTTTAAACTTAGAAGAATATGAAAAAACTGGAGAAGCAAAAGTAATGCAGTTGAACTCTTCTTCAGAAGAAAATAAACCAGCCATGATACCTCAGCCGGAGATCAAGCAAGAAATGAAGGAAGAACCTCAAGATGATGTTCCTAATGATGACAAACCTACTCATCATGATAACTTAGTAGATGAGAAACCTAACCTATTTAATCTTCCTTCGCAAAGTCCTGCTCCTTCTCTTTCCGGCTCGGAAAATCATAGTATTCCCCAAACATCTCGGCCAAATACTCCCAATAACTTAACTTTAACCTCAATCATTGCCTCACAACTCGGTGATTCGATAACCACGACCAGTACTCCATGTTCCATGGCTGTAACGTCAAGCAACAATCACTCTTTAGTTAGTACGATGTTACCACCACCTAAATTAAATCATCCTCAAAATTTTTCTACACCGAATCATGTCCAAGGAATGATGACCTTGACACCAAATAGAAGTTTGAGCCCAAACCGAGGGGATTTTCCTACAGGTGCTGGTGGAAATAGCAATGGGTCGAATAGTTCTGGAGGGTCTACTGGAAAAAGAGCAAACAGAACTAGATTCACTGACTACCAAATCAAAGTCCTGCAAGAATTCTTTGAGAATAATGCGTATCCTAAAGATGACGATTTAGAATATTTATCAAAACTGTTAAGTTTGAGTCCTAGAGTGATTGTTGTTTGGTTTCAAAATGCAAGACAAAAAGCACGAAAAGTATATGAAAATCAACCAGCTATAGAACCTGCGCCCGGTATACCCGACGAAGCAGGAGCTAATCGATTTCAAAGGACTCCTGGATTAAATTACCAATGCAAGAAATGTTTGCTGGTCTTCCAGCGTTATTATGAATTAATTCGGCACCAGAAAACTCATTGTTTTAAAGAAGAGGACGCGAAGAGATCTGCGCAAGCACAAGCAGCTGCCGCTCAAATCGCTGCTGTACTTAGCTCAGAAGACTCCAATTCAAGCACAACCATCGAACAAGGACAACAACAACCTCCTGTCCCACAAAGTCCTCAAATTCAAGCACCTAGCCAAAGTCCTGTGCAGCAGCCTAACCAACCTACCACACCCACGCCATCCGGGTCGAATTTTCCTACGTCCCCTATTTCCACACCAACTCCAACTTGTGACTCCAAAGAAGGAACATTTCAATGCGACAAATGCAATTTAGTATTTCCTAGATTTGATTTGTGGAGGGAGCATCAACTTGTACATTTGATGAACCCAAATTTATTTCCTAGCTATCCGCCTGATTCCCCATTTGGGATTCTTCAGCAACACGCCCAACTGCAACAACTAAACGCGGCGGCGGGCATGGATCTAGCCAACAACAGTGGGTCTCCTATTCAACAACACCCACTTATGGGCATGCTCAACAACGCAGCCGCCGCGGCAGCGGCCGGACAGAAGCGCAAGTTTGACGACTATGAAAGCGAGAGTGATATAAGTGATCAACCAAAAGACAAACGTCTACGTACAACAATTCTTCCAGAACAATTAGATTATTTGTATCAAAAGTACCAAATAGAAAGTAATCCGTCGAGAAAAATGTTGGAAAACATTGCCCGAGAAGTCGGATTGAAGAAACGCGTAGTCCAAGTCTGGTTTCAAAACACTCGCGCGCGAGAACGCAAAGGACAATTCCGAGCTCACGCGCAAGTTATCAACAAGCGTTGTCCATTCTGTCCAGCCCTATTCAAAGTGAAATCAGCGCTGGAATCCCACCTGACGACAAAACACGCGGACCAATGCTCCCGAGGAGAAATTAACATCGACGCACTGCCTGACGAGGAATTAAGCATGGAATCCTCGCCGAGTTTCTCTTCCGGACAAGGCGGGGAAAAATTTCCGCAGACGCCGAACATGATGCCGCCCCTATTTCCGCCCTTCCACCCCGATATGGAAAACTCAATTAAGAAATACTACGAGGAAAGCATGAAGCGGTATATAAGTGAGCTACAAGCGCATGCTGCCGCCACCAACGGCGACAAGAGCGAGATGAAAACGGGGAAAGAAGAGGGAGAAGTTCCACTGGATCTTTCAAAACCTGTCGATTTATCCCGACCTATGAAAGTTAGCATGGATCACGAGAGGTCTCTTATAGATACTGGTCCACTAACAGACTTGAGTGAACGTTCATTATGTGATGAACGCAGTGATTCCATGTCGGAAACGACTGAATTTTTCGACGATGAAAGCAATCCCACATCACCGGCGAGCAGCACGCAAAGCAACCAACGACACGGTCAAGTCGGCGGCGGTAGTGGATCGAAGCGTTTTCGCACACAAATGTCCTCCGTTCAAGTAAAAGTAATGAAATCCTTATTCGGCGATTACAAAACTCCAACCATGGCCGAATGTGAGATGCTTGGTCGCGAGATCGGCCTTCCAAAACGCGTGGTGCAAGTGTGGTTTCAGAACGCGCGTgctaaagaaaagaaaaataaattagccatgcagaaaatgCTGGGCACTAACGAGACTGATACGCCAAAGCCCCCAGAAGACTGCAAGTACTGCGCGTTCAAATACTCGCATAAGTATTCGGTGCAGGACCACATCTTCACCAAAAGCCACATCGCGAACGTGAGGCTGGCGATCGAGACGAGTGGGGGTGGGAAGGACGGGTCGGTGAGCGACGGCGGAGAGTTCCAAGTTCCGCCAGTACCGGTACCAGGGTCATCATCGAGTGTTGCTGACTCCACGACCGTCAACAACAACACGCACCTCGCCCAGATGCAGCTCCTGCAGATGGCCGGCATGCAGATGAAGGACAAGGAGCAGCAGGAGAGCCAGGACGCCCTCTTCCAGCAGCTGTACGCCCTGGGGGGAGGCAACAACCCCAACCCGGCGCAAGGATTCGGCGCCCCAAACCAGTTCCTACACCCCGCCATGTTCGGAGGAGCGAACGGTGAGTGA
Protein Sequence
MPTLSAAPELSPGGRTERHKLELSADMSPEQEASPPPAAPGASPPPQPTRLPPSPAASHTSHASHHDTTSDVEQFSGKIVYNPDGSAYIIEDSESESETTGPVLPEVVPPLQAVYVSRLLSRHQTARQQQEPAAVHSYRVVALRDARPPRPASVPVKPILMCFVCKLSFGFARSFAGHAQAEHGVTLAEAEREVLAADCSAILQCVGADKRPMVSLLEPLGPAAPPAHQDMMQGQQPMDATRADRSSPEHQHHQQHLAMQQHQLQQQRLTPGKSPSPPFAAPPAFMTGTTIGVCPEHLQGRPSGADCPRCELILASGRLGPAGLGNVHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGAPSAVESRQASPKAPPMHHSPVSSGHKPKPSFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALHHQQQQHSQQQHLESLFGAAAAAGHAGLYPGLGDKPEAALADMAYNQALLIQMMTGGQLPGHGGPADLAPHADLGLNPDTMEPPPEPADPDPEKTYQCCVCNVFNSDSLDELGRHLAQDRTRLREQEILAVVAGHYVCKLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGVRNEWKLKYASAPGGVQVRCNACDYYTNSAHKLQLHAAGARHEAGAALLAHLAERCRQLRPDQPRVFHCALCGFTAPARLPLLQHVRSLKHLHLEQLHQLQRRAEGKDATPEVGEVFQVISQPLPPSTPTEQHSPVDRKELVQPDVKMTPESMKDQFKYEPRDDSSEDVGGGGGAPGGEATTPQHACPYCNYTSNSEMRIQAHVLAQHGAQASTPGPQPDTPSTTPTNPGAHGHCFQCPLCQDSFKDRPSLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQVSRTSTPSQTPNAQHTPPNQLVSPSSVSSKDSVKLEKQDGNNVDLEPDLMSPNSEEISEYETERCSTCFKNFRNIDELCFHQNETGHLEIKQTPSGPGYVCWKKGCNQYFPTAQTLQMHFKDVHAKNSVSQMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSVVALHKHVETVHSELTDEELAAYKQSLMNNPLLLAGLQGQVLDSSTNELLKKESMRDDNMLDASPGEGDDAKDVSGATDASDANQTMDGDNSDDSIVYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQQNNNNNPAVSPVLQQPTAAAVALATGQTRGGAGSPDEDDKKRYKCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLTKPLIEQPESMSAVQSPKQPAGAPLQPSPSPGPGQGAGGDKRSPTPASPGPGPATCQQQGMLGCPKCGALFSTQEQLSAHQQLYCMFAAPMAIFQQGQEPGQAKSPPPSDQDLAARLNLPRKTGSHMYKHLLESFGFDLVMQFNENHQRRQREEQQRAATRTPTPPVAAPPAPLPVEEPVAPPQDVTRLEEEPELNNLPEVHKSTCQHCNKEFSSVWVLKSHCEEIHKDLVPLEFLEKYAQQFKNEYEKKSVVVTAATSSTLSTTPRVSTPGAPTTTTPSAEASTPEKEDDKEALHAKLNLTTEANSTAPSTPTSSGTPVSGTESVPANIQAILAQSMAQNPMALAQQMSEMQAALNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYADPIGQFGPQDQQAMMAKQQQALLQQQQAAANAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMAGQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMQLNSSSEENKPAMIPQPEIKQEMKEEPQDDVPNDDKPTHHDNLVDEKPNLFNLPSQSPAPSLSGSENHSIPQTSRPNTPNNLTLTSIIASQLGDSITTTSTPCSMAVTSSNNHSLVSTMLPPPKLNHPQNFSTPNHVQGMMTLTPNRSLSPNRGDFPTGAGGNSNGSNSSGGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLSLSPRVIVVWFQNARQKARKVYENQPAIEPAPGIPDEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTIEQGQQQPPVPQSPQIQAPSQSPVQQPNQPTTPTPSGSNFPTSPISTPTPTCDSKEGTFQCDKCNLVFPRFDLWREHQLVHLMNPNLFPSYPPDSPFGILQQHAQLQQLNAAAGMDLANNSGSPIQQHPLMGMLNNAAAAAAAGQKRKFDDYESESDISDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLTTKHADQCSRGEINIDALPDEELSMESSPSFSSGQGGEKFPQTPNMMPPLFPPFHPDMENSIKKYYEESMKRYISELQAHAAATNGDKSEMKTGKEEGEVPLDLSKPVDLSRPMKVSMDHERSLIDTGPLTDLSERSLCDERSDSMSETTEFFDDESNPTSPASSTQSNQRHGQVGGGSGSKRFRTQMSSVQVKVMKSLFGDYKTPTMAECEMLGREIGLPKRVVQVWFQNARAKEKKNKLAMQKMLGTNETDTPKPPEDCKYCAFKYSHKYSVQDHIFTKSHIANVRLAIETSGGGKDGSVSDGGEFQVPPVPVPGSSSSVADSTTVNNNTHLAQMQLLQMAGMQMKDKEQQESQDALFQQLYALGGGNNPNPAQGFGAPNQFLHPAMFGGANGE