Hrub064220.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Harpalus rubripes
Gene Symbol
Thap1
Assembly
GCA_963082715.1
Location
OY720461.1:4476070-4489794[+]

Transcription Factor Domain

TF Family
THAP
Domain
THAP domain
PFAM
PF05485
TF Group
Zinc-Coordinating Group
Description
The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion. It features the conserved C2CH architecture (consensus sequence: Cys - 2-4 residues - Cys - 35-50 residues - Cys - 2 residues - His). Other universal features include the location of the domain at the N-termini of proteins, its size of about 90 residues, a C-terminal AVPTIF box and several other conserved residues. Orthologues of the human THAP domain have been identified in other vertebrates and probably worms and flies, but not in other eukaryotes or any prokaryotes [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.9e-16 2.2e-14 56.2 1.1 1 87 4 79 4 79 0.84
2 2 0.00013 0.016 18.3 0.0 48 85 692 725 681 727 0.70

Sequence Information

Coding Sequence
ATGGTTGGCTGCTGTGCCTTTGGTTGCTCCAATCGGTCAGAGAAAGGATTTCTTATGAAAGCATTTCCTACGGATCCGGATCGCAGAAAAACATGGGCAGCTAAAGTGAAACGAGAGGGTTGGACACCAACTAATTCGTCTCGACTTTGTGaaATCCACTTTGCACCTGAGATGTGGGAAAAGACGAGAGAAGATGGCAAGAGGATTCTAAAACATAATGCGATTCCCACAATATTTAGTTTTACTGTACCGACGAAGAGAAGAAGGTCGCCGGTGAAAAGAAGATATCCAACACTTCAATTACCTGCCCCTGAAAATGTAGCAACGTTTGAACCACAACCCTGCACGTCTACAGCAAGAACTGAAAATAAAGGATCCTCCTCTTCAACAAGTTCATCGCCAGTACGATCATTATCACCAATGGAAGAAAAACtacgattaaataaaaaattacgccAATATGAGATATCGTATAGGAAATTACttcataaaacaataaaatataagaatcaaGTTCGAGCTTTGAAACGGACAACTAAACGTTCTAATTCTGAAGATGAAAAATTGTTACGCAAGATTTTTAatgatgatcaaattttgacattacgaAGGAAATccacaaaatttatgaaatggtCCAACAGTACCATGATGAGagctataaaactaaaattttcttgTGGAACTAGTGGATATGAAGAGTTGTTACggcaaaaaatacctttaccaTCTCTTAGAACAATAAGCAGGAGATTGCAGaatattcattttgatagtggtatattacatgaagttttttcatttctaaagtTAAAGATAGAAAGTTTCAAAGAAGATCACGAAAAAGATTGTGCTCTAATTTTGGATGAGATGGCAATAACACCAGGAAATACATATGATACAGGACTAAAGAAATATTTGGGTACTGTAACATTACCAAAACATGAAGGAACAGCAACTCACGCTCTGGTAGTTATGATTGGAGGAATTACTGCACGTTGGAAACAGACAGTGGCTTACTATTTAACAGGAGACTCAGTGAATGGTGCTATATAccaagatattttatttgaaattattaataaaacggAACAGCTGGGTTTAAATGTTTTAAGCATCACATCTGACATGGGCGCGTCTAATCAAGCCTTATGGAAACTGTGGCAAATAACAGCAGGAAGATATTCCCAGACCCGCAATTTTATTGTGCATCCAACTAAtccacagaaaaaaaattacatttttgcaGATGTtccacatttatttaaaaacatcaagaatATGCTTATGAcgaataaaacaatagaaatatccgaaaatatcagaataaaacataatttaccaACAAATGTTATATCTGCTCAGCATATTCATGAACTTTTTGACTTTGACAAAGATCATGATCTTCGGCTTGCACCCAAATTAACAGAAGAAGATTTAGCTCCGACTCACTTTCAAAAGATGAAAGTATCGAAGTCTACCCACGTCGTAAGCCATGATGTTAGtagtggtttaaaatttttaagcgATGAGCTAAATAAACCAGAATATAAAACAACAGCATGGTTTCTGGATACTTTAGAAAAGTGGTTTAAATTGATGACTTCACGCCATCCATTATTTGCattaagcaaaataaaaattgatgaatATGACAGggctatttcatttttaaaagaagtagtagaattattttctactttaaaagtTGGGAAACAAAAAATGTGGAAACCATCGCAAACAGGATTATTAATATCAACAGAATCCGTTCTTAACCTTCAGGAATTTTTGTTAGAAAGTAAAGGTTATAGTTTTGTTCTTACTTCTAGATTTACGCAAGATTGTTTAGAGAATTTATTTAGTGCAATTAGATCTAAACAAATCATACCAAATGCacagcagtttaaaaataacttaaaattaataactgtttcacaatatttaaaagatgtTTCCAAATCGAGTTATGATAAAGATGAAAGAGAATTTTTGTCAGACTTTTTGGACGTAGTAGCAACAAATACTGCACCAACATATGATATAgaAACAAATTTGTGCATGGGAAAGAAATCGTCAAACTATATGACAGTATGTTCCCGTCATTTTAAAGCACAAGATTACATTTGTTCTGGTTGGAGTAATCAGCAGCGCCTGTTGGCAACAGCTGTACCTACAGAAAATTTACCAGTAAGAAGCGACGCTCTAAGTAGTCTGCAGAAGAATGTAATACAAAGCCGGAAAATTGCAAGGCAACAACGAATAAATAGGAGACGTGCGACAAGTACAGCTACAAGTGCTAGAAAAGTAAACGACGATCAGCTGAATGATTCTAATTCAGAACACAGACCACATTCTGAAATACTTGCTGCAGAAAcaatattaatgttaaataataatagtgtAACACCTGTAAAAGAATTTAGAGATATAGGTATACAGGGAGAAGACAATAATAATGCCAATTTTCAAGAAGGGAGACAACAGAAGTTGTGGAAATTACAGAGGAATATCACTCTTGTGCGTAACGGCTAA
Protein Sequence
MVGCCAFGCSNRSEKGFLMKAFPTDPDRRKTWAAKVKREGWTPTNSSRLCEIHFAPEMWEKTREDGKRILKHNAIPTIFSFTVPTKRRRSPVKRRYPTLQLPAPENVATFEPQPCTSTARTENKGSSSSTSSSPVRSLSPMEEKLRLNKKLRQYEISYRKLLHKTIKYKNQVRALKRTTKRSNSEDEKLLRKIFNDDQILTLRRKSTKFMKWSNSTMMRAIKLKFSCGTSGYEELLRQKIPLPSLRTISRRLQNIHFDSGILHEVFSFLKLKIESFKEDHEKDCALILDEMAITPGNTYDTGLKKYLGTVTLPKHEGTATHALVVMIGGITARWKQTVAYYLTGDSVNGAIYQDILFEIINKTEQLGLNVLSITSDMGASNQALWKLWQITAGRYSQTRNFIVHPTNPQKKNYIFADVPHLFKNIKNMLMTNKTIEISENIRIKHNLPTNVISAQHIHELFDFDKDHDLRLAPKLTEEDLAPTHFQKMKVSKSTHVVSHDVSSGLKFLSDELNKPEYKTTAWFLDTLEKWFKLMTSRHPLFALSKIKIDEYDRAISFLKEVVELFSTLKVGKQKMWKPSQTGLLISTESVLNLQEFLLESKGYSFVLTSRFTQDCLENLFSAIRSKQIIPNAQQFKNNLKLITVSQYLKDVSKSSYDKDEREFLSDFLDVVATNTAPTYDIETNLCMGKKSSNYMTVCSRHFKAQDYICSGWSNQQRLLATAVPTENLPVRSDALSSLQKNVIQSRKIARQQRINRRRATSTATSARKVNDDQLNDSNSEHRPHSEILAAETILMLNNNSVTPVKEFRDIGIQGEDNNNANFQEGRQQKLWKLQRNITLVRNG