Hsub011321.1
Basic Information
- Insect
- Harpagoxenus sublaevis
- Gene Symbol
- -
- Assembly
- GCA_030770355.1
- Location
- JASTWR010000064.1:337274-339653[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 7.8e-06 0.0014 20.3 1.5 1 23 196 220 196 220 0.98 2 7 6.8e-05 0.012 17.3 4.0 1 23 226 250 226 250 0.98 3 7 5e-07 9.1e-05 24.1 1.7 1 23 256 280 256 280 0.99 4 7 0.00087 0.16 13.9 0.5 1 23 286 310 286 310 0.96 5 7 8.1e-07 0.00015 23.4 0.4 1 23 316 340 316 340 0.98 6 7 0.00017 0.031 16.1 1.6 1 23 346 370 346 370 0.97 7 7 4.1e-05 0.0074 18.1 1.7 1 23 376 399 376 399 0.98
Sequence Information
- Coding Sequence
- ATGTCGGCTGAAAGTGCGGATTCTCCGAATTGCATTGCGAAtcaggaggaggaggaggaagaggaggagatgATTTTGCACGAGCCTGAgAATAATCCTGTGGATATTCTGGAGTGTCTGTCGGTTATGATCAATGAGAGTAGTGGGAAGGATGCGAGCCAAGTACAGGAGCTTATATTGGACGACCAGTTGCTTGGCACAATGGTGACTACGATTACGTTACCCGATGGAACTCAGGCTTTTGTTACGAATAATCTCAGTGACATTGATCCAGATTTCAAGACACAAACATTGCAAACGACGCTCGAAAACGGAGATACTATCTTGCTGCGAGATTTTTCGGAATTTGGCGATGGCAAGGCTCTCCAACTGGAATTAGATCCAGCTACATTTGTACAAGCCGAAGACGCTGCTACTGAAAATGTAGAGAATACATATTCGCAGGTGGAATTTATCAATGGCACTGCGTACATGGTAGCCGGCCATGTGGACGTAGACGAAAGTTTATGGGAGATTGAAGATGGGaagttaaagaaaaaagatcccaagattttaattaataagcTATCTGACACAAAAGTTAGGTATCCTTGTCCCAGGGAAGGATGTTCTAAGGTTTACAGCACGCCCCATCATCTCAAGgtTCACGAGCGTTCACATACCGGCCAGAAACCATATAGATGTTCTCATCCAAAGTGTAAAAAGAGCTTTTCAACCGGTTACAGTTTGAAAGCGCATTCAAGGACACACACGGGTGAGAAACCGTACAAATGCACGAATGAAACGTGTAACAAGAGTTTCAAGACGTCGGGCGATCTGTTAAAACACGTGAGAACTCACACGGGAGAACGTCCCTTCGTATGCCCATATAACGGTTGCGGCCGATCGTTCACCACGAGTAACATTAGGAAGGTTCATGTGAGAACGCACACTGGCGAGCGACCATACAAATGCACCCAACCGACATGTGGTAAAGCGTTCGCTAGCGCGACAAATTACAAGAATCACATACGGATACACTCGGGCGAAAAGCCCTACGTTTGTTCTATAGAAAACTGTGGTAGACGGTTTACCGAATATTCTAGTCTATATAAACATCATCTTGTACATACGCCTCAACGACCATTTGAATGCACACTATGCTCCAGAAAATATCGTCAAAGTAGCACGCTGGTGATGCACAAGAGAACAGCTCATGCGTTGGTCGACAGTGACGACGGTGCCGATGCATTTTTGCAAGATTCTCCTGAACCCTCTAGtccgaataaaaataaaaaggccGTGAAAGAAACTCATAAGCTGCTACCGAAAGACAAACAGATCCAGGTTTCTAAAATAATCGACGACGCAAACGAGAAAGAACCACAAATTTTGTTGGTGGGCGATTCTTCGCAAATCGCTGCATTACAGAAGATCGATCTGGACGAAAGTTTCGATGATCCTGGCATTGATACAACGTTCGAAGGATTGAATATCAAAATGGAGGACATAGGATTTGAATGGACCTAG
- Protein Sequence
- MSAESADSPNCIANQEEEEEEEEMILHEPENNPVDILECLSVMINESSGKDASQVQELILDDQLLGTMVTTITLPDGTQAFVTNNLSDIDPDFKTQTLQTTLENGDTILLRDFSEFGDGKALQLELDPATFVQAEDAATENVENTYSQVEFINGTAYMVAGHVDVDESLWEIEDGKLKKKDPKILINKLSDTKVRYPCPREGCSKVYSTPHHLKVHERSHTGQKPYRCSHPKCKKSFSTGYSLKAHSRTHTGEKPYKCTNETCNKSFKTSGDLLKHVRTHTGERPFVCPYNGCGRSFTTSNIRKVHVRTHTGERPYKCTQPTCGKAFASATNYKNHIRIHSGEKPYVCSIENCGRRFTEYSSLYKHHLVHTPQRPFECTLCSRKYRQSSTLVMHKRTAHALVDSDDGADAFLQDSPEPSSPNKNKKAVKETHKLLPKDKQIQVSKIIDDANEKEPQILLVGDSSQIAALQKIDLDESFDDPGIDTTFEGLNIKMEDIGFEWT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00110025;
- 90% Identity
- iTF_01407624;
- 80% Identity
- -