Hsub001883.1
Basic Information
- Insect
- Harpagoxenus sublaevis
- Gene Symbol
- -
- Assembly
- GCA_030770355.1
- Location
- JASTWR010000005.1:1901936-1905414[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 2 3.6e+02 3.3 0.7 3 23 258 278 258 278 0.89 2 12 0.059 11 8.1 0.3 1 23 283 306 283 306 0.86 3 12 9.5e-05 0.017 16.9 0.5 3 23 320 341 319 341 0.96 4 12 0.017 3.1 9.8 0.5 3 23 354 374 354 374 0.98 5 12 3.1e-07 5.6e-05 24.7 1.7 2 23 415 436 414 436 0.97 6 12 0.037 6.8 8.7 0.1 1 13 441 453 441 464 0.75 7 12 1.1 2e+02 4.1 1.6 2 23 532 553 532 553 0.96 8 12 1.6e-05 0.0028 19.4 1.4 1 19 561 579 561 581 0.96 9 12 0.028 5.1 9.1 2.5 1 22 618 639 618 639 0.95 10 12 0.00011 0.02 16.7 0.9 1 23 665 687 665 687 0.99 11 12 0.011 2.1 10.4 0.0 1 23 752 775 752 775 0.98 12 12 7.2e-07 0.00013 23.6 5.9 1 23 780 803 780 803 0.98
Sequence Information
- Coding Sequence
- ATGGCCGCGGACAGCAAGTGGGACAAGGTCTGCCGACTGTGCTCGGAGGAGAGGAACGAGATGCTGCCCATCTTCGGCGACGAGGGCCTGCAGCGTAGGGTGGTGCATAAGCTACGCGCCTGCCTGCCCGTCCTCGTGTACAAGACCGATCCGCTGCCGAAGCAGATCTGCCAGTTCTGCGCTGCCAGGCTGGACGACGTGTACGAGTTCAGGGAGTACTGCCTGAACGTCTACAGGGGCATGCACGCCGTGTTGCTGAGGCACAAGCAAATGGAGTCCGCCCAGATATACCTCGACGCGATGAGGAACTCACCGGATCCCTGCCAGGTTCAGCTCTGCAAGGAGAAGTCTAGAGCTCCACCACCGTTAGTTCCTTTATCAGCTGCCCTACCCTTCGACGACTCGGCGATACCAATCAATCAGGCCAACCAGGATCTCCAGAGTGCCTGCATGGAAACCTTGTCCGAATTGCCATGCGAGGTGGAGATCAAGGAGATGAATATGGACCCAATTTTGAGTGCCGAAACCGCCGTTTGCGAGCCGTTGAACAAGAAGCGCAAACTATCGGAGATGTTCGGCATGGATATACAAATAAGAGCGGATTCCGTTCCTATACCTGATATGGAAGGAGCGAGAGCTCCTAAACTGGACTACCAAGCCAAAAAGGAAGAGAAACGAACGAGTATTCTGGAACAGGTGCTGACCGGCAGTCTGACGATGAATAATCACCAGAAACTGCAATCCATAACGAAGTTAACTTCCGAATGGTGGTGCTCACCCTGCAACAATTATTACAAGACGAAGGACATTCTAATGAAGCACATGCAGTTGCACTGCCCGCGTGTATATACCTGTAAAAAGTGCTCCGAAACCTTCGAGTCTGTAGAAATCTTAGCGAAACACGAAGCCAGTAGTCATTTAAAGGTTGAGCTGGATTTCACGGGAAATTTGAATGATTGTGATCAGTGCGATCGGCAGTTTGTTCGCTGGGAAATGCTGAAGCAGCACAGACTGCGCGATCATCTGGCCGAGTCGACCGAAATTGGAAGTAACACGTGGTGTTCATTGTGCAATAGATTCTTCCCTACAGTAGAATCTTACCAGAGCCACGTTCAGTTACATCAAACAAACTCGATAGTGCCGCAGAAATTGCCACCTTCGGAATCCACAGTGACAAAAATAGTGGAACGACCGAGAGAGATTAAACGAGATGAGCAATACTACGAAAACGTGAAATCTCTCAGGTGTCCTACTTGCGGGAAGATTTGTACCCAGCAGAGCGCATTATCGAATCACATGCGCACTCATGAGCCAAAGAAGCACAAATGCGACATTTGCGGCCGGTCATTCGGACTTCTTGTACGCCTGGCTGGACACAAAATAGCCGAGCATAATGAACAACCAATGATGACACCAGTCTTGTCGGCAGTCGAGCAAGAGGAGGCCTTAAATGCCGAGAGGGAAGCGAGAGAAGCAAGGGAAGCTAAAACTCGTGGTAACAAGAAATCTTACTCCGAGGTGATGGAGAGAAACGACGTCCCGATAGATGATGAATCCCCAAAACGCATTTCTGGTGGACATAAAAACGTAGCAAGATGCGGCATTTGCTTACAATGGTTCAGCGACCACACGACAATGTTAACGCACCTTCAAACGCACTCAGACAATTCCCACAAAAGTTACACGTGTCATGTATGTAAAAAATCGTTTAAGGAACAGTCGCAGCTGTTAAAGCACGAGGCTTGTCATAAACGCCTAACGCTCGATAATGCCTCACCGTACACATCCGCTGTTTGCAACAAATTATTCATGGATAAGGCGCATCAAAAGCCGCACATGGTGGATAAAACCTATCACTGTGCGAAGtgtaataaaatctttttcaaaGAAGTTACGCTGCTCGCCCACCAATGCACGGGCGGAGCACTGCTTGGAAAGAAAGTCGCCACGAAGTCTCGGCAGAAGACGTCGTCTCACGTTGGCAACAAGACGTACAAGTGCTCCAAATGTGACGCGACTTTCGCGAGTTCGCAGTCACGAAACGCTCACTTAAAAATGCACGCCGAGTATATGCGCGGCAGTACGACGCAGACACATGAGATTAAAGTCGAAGCGGATGACGAACCGATGCCAAAATTGCGTCCGGAGACGCTGTTGGAATACAACGTATCTCCTATCGAGCCAAAGGTTGAAATTAACGAGCAGAGTACCCCACCACCTCTTAAACGGACCCTTATTAAAACTAGCAAGGGaTATCGGTGTGGTGTATGCCAGTCACCGTTCGTGTCGAGGGATCTAGCCGTGGCGCATTTGAGATCCGCACATCCCGTGATGCCATATCAGTGCCCTTATTGCAAGAAACGCTTCACGACGCAGTACACGTTTACCCATCATATCAAGACAGAGCATCCCGACGAGCCCGAGAAATGA
- Protein Sequence
- MAADSKWDKVCRLCSEERNEMLPIFGDEGLQRRVVHKLRACLPVLVYKTDPLPKQICQFCAARLDDVYEFREYCLNVYRGMHAVLLRHKQMESAQIYLDAMRNSPDPCQVQLCKEKSRAPPPLVPLSAALPFDDSAIPINQANQDLQSACMETLSELPCEVEIKEMNMDPILSAETAVCEPLNKKRKLSEMFGMDIQIRADSVPIPDMEGARAPKLDYQAKKEEKRTSILEQVLTGSLTMNNHQKLQSITKLTSEWWCSPCNNYYKTKDILMKHMQLHCPRVYTCKKCSETFESVEILAKHEASSHLKVELDFTGNLNDCDQCDRQFVRWEMLKQHRLRDHLAESTEIGSNTWCSLCNRFFPTVESYQSHVQLHQTNSIVPQKLPPSESTVTKIVERPREIKRDEQYYENVKSLRCPTCGKICTQQSALSNHMRTHEPKKHKCDICGRSFGLLVRLAGHKIAEHNEQPMMTPVLSAVEQEEALNAEREAREAREAKTRGNKKSYSEVMERNDVPIDDESPKRISGGHKNVARCGICLQWFSDHTTMLTHLQTHSDNSHKSYTCHVCKKSFKEQSQLLKHEACHKRLTLDNASPYTSAVCNKLFMDKAHQKPHMVDKTYHCAKCNKIFFKEVTLLAHQCTGGALLGKKVATKSRQKTSSHVGNKTYKCSKCDATFASSQSRNAHLKMHAEYMRGSTTQTHEIKVEADDEPMPKLRPETLLEYNVSPIEPKVEINEQSTPPPLKRTLIKTSKGYRCGVCQSPFVSRDLAVAHLRSAHPVMPYQCPYCKKRFTTQYTFTHHIKTEHPDEPEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01520514;
- 90% Identity
- iTF_01405986;
- 80% Identity
- -