Haxy005600.1
Basic Information
- Insect
- Harmonia axyridis
- Gene Symbol
- METTL18
- Assembly
- None
- Location
- chr5:39668046-39687110[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 5.6e-06 0.0005 20.9 2.5 1 23 133 155 133 155 0.98 2 12 0.0039 0.35 11.9 0.0 1 23 162 184 162 184 0.98 3 12 0.21 19 6.5 0.7 3 23 201 221 199 221 0.96 4 12 0.0013 0.11 13.5 0.6 2 23 228 250 227 250 0.96 5 12 2.8e-05 0.0025 18.7 3.6 1 23 270 292 270 292 0.94 6 12 3.7 3.3e+02 2.5 0.2 1 23 304 326 304 326 0.93 7 12 5.9 5.3e+02 1.9 0.5 1 23 332 355 332 355 0.87 8 12 0.0047 0.42 11.7 1.3 2 23 362 383 361 383 0.96 9 12 1.9e-06 0.00017 22.3 0.9 1 23 411 433 411 433 0.98 10 12 0.00078 0.07 14.1 1.4 3 23 441 461 439 461 0.97 11 12 7.5e-05 0.0067 17.3 0.3 1 23 467 489 467 490 0.95 12 12 0.044 3.9 8.6 0.5 1 23 504 526 504 526 0.96
Sequence Information
- Coding Sequence
- ATGGGTGAATGTTATAATTATTCTTGGGAAAATCCAACAAGTTTTATTGAAGAGGGAGAAATTATATATGATGCGGAAGAGATTTTACCAGTCAATACAGAAGAAATTACATGTGATACACAATCGACAGATACATCACTAAAACATTCTGAAAGTGAGAGAGATCTGCAAGAAGAAAAACTATACTTTTCAAGTGACGACATCTTCACCAAGCAACTGCCAAATGAGAATGAATATTTAGTTTTGCCTATGGAAGATCAAGTGATTGAAGAAACAGTAATTGAACAGTGGATAGGAGACAGTACTCAAGAGATTGTCTCAAATGAACTAACTACTGTGGAAGATAATCAATATCAGGTTCCTTTGCAACAAGATGAATATATTACTTTGAGGCCTTATCCATGTGACTTCTGTAACAAAAGATTTAGGAGTAAGACTAATCTTACAAATCATTTGTCTTCTCATCAAAATACTCATGATTACTATGAATGTAATGAATGTGGACTTGGGTTCATCAATATAAATGAATTATTAGGACATAAAAAAATTCACGAGAATGAGTCAAAATTTTCTATAGACAATAGCATTCAGTATCTTGCATGCATGCATTGTGCTGAGGGATTCTTCAGTCAAAAAGAATTGGATTCTCATCTGAAGTTACATGAAGCAAAGCCTCCATCTACATGTCTAAAATGCGGATTAGATTTTATAAACTCAAGATCATTGATGGAACATCGGCGAAGAGCTCATGGATTTAAAGATGATCGTCATAAGGTTCGATTGAAACAGAAAAATAAATTTGGGACATATTCTTGCATAACTTGTGGAAAATCTTTTTGTCGACAAGATGATCTCAAGAGACACCAACAAAATCATATTGATGATGTGGTTAATGATCCTGAATCAGGTTTTACTTGCAGAGTTTGCTGTGAAACGTTCGCAGAACCCCTTGACCTTTTGGCTCATGCTGAGGAGCATGCTCGTGGTTTCGAATACAGTTGCATGGTTTGCTCAGAAAATTTTATAGATGAAGAAACGTGTGCCGTACATGTTAAAGAACAACATCCCGAAGAAGAAGGTTTACACTGTAGCAAATGTCCAAGGATTTTTTATGATATATCCAGATTAGAAAAACATCTGCTGTCACACAAAGATGAATCTTTAATGAATAATGTGCATGATCAGACGACCAACAGATTTAAAAACATTGGTAAATTATCAGATCAGCAATTTTCATGTCAAGAGTGTGGAAAAAGATTTGCTACCAGAAGTTCTCAGCAAATACATATGAGGATACATACAGGCGAACGTCCTTATGGGTGCAGTTTTTGTCACAAAGCTTTCACAGATGGGGGTACTCTCAGAAAACACGAAAGGATTCATACTGGCGAGAAACCTTATGCATGCGTCATTTGTCCCAAAGCTTTCAATCAGAGGGTTGTCTTGAGGGAGCACATCAGATCGCACCATTCGGGCCCTGATCCAAGTTGCTCTGATAGTATGACGCCGTTTCGTTGTACCATCTGCTCGGACATGTTCTCCGAATCCCAGGATTTAATAGTGCATGTGATTCATCATTGCGATATAAATACTGCAATGAAAAGAAAACCCAAAGCCGGTCCCAGAAAATACGTTCGCAGATCCAAATTGAAAAGCCAAAAAGTTCAAGAACAAGATGAGTATGACTTTCAAGAGGAGAACGAAGAAGATGAGCATCATCAGCAAAGCGGGACAATGCCCAACTATGAAATAGACATGGATGTTAACCAGACGCAGGACATGAGAAACACTCTTTCGGAGCATGAATATGAGGACATGGATGTCGATCAAGAAATGTCACATTCTTCAACGCCAATTTTAGAATTGCCTGAAATGGAAAATAGAGAAGAATTGCGAGATACCTCAGTCGTTACTTCAAGGGCGAAAATGATACATACAGAAAAAAAACCAAAGATTAATCCAGTTGAAACTAGAGGAAGGAAAAATAAAAAAAATACTGTGAGAGAATTTTTGGAAGGTGTCAGACCAAGAACAAAAAATGTCACTTATCCTGTTCAAGAACAAAGCAAGCCATCAATAGCAACTTTTCCTCCCAGGAATTCTCGAAAAAGAAGGAAAAACCCAAGATTTCAGGAAGAATTTTATTCTGACCATACTGAAAGTTTGGATGATTCAGAAGAACAAATTGAATATAATGTTCCAGAAAAAAGGGCTAGAAGAATATCTTTGAGAAAATCAAATATTGGTGATGCAGAAATTCCTGAAAAAACAAGCAAGTTGAAAGAAGAACATAGTATTGGTGAATTTAGCTTCAAACAAGAATTTGAACAGTGTGAACAACAAATTGTTTATGAAACACCTGATTTATATGAAATTCCTGAATGTCATTCAGAAACAATCGTTAAAGATGAAGCTTCGGAATATGCAAATATAATTAGTCCTTCGAAACCGGAAGATCAGAGAGATGTTGAAGTTCAGGATTATAGTGTACAGCATGAAATTATCGATCCTCTTCTGGAATTAGCAGAAATATCTATGCAACATGCTAAAAGCGTTAATAAATGCGATATGTTCTGGGTAACAGTTACTTTCATCAGGAAATTATTCTTGAAAAACCAATTGCTTGACTGGAAAATATTTGAAGAAAAAAATATTATATCTACTCATTACAATACTGAAGAAAACACCACAAACCAACTATCTAAAGATGTTGTCAATCAATTCATTAAAATATGGTATGATGAAATAAGTATAGATGATAAGTTTCCAACAGAAAGTGGTCTTTTTATCAAAAATACTTTGGTTTCAATCAATGAAGCACTCAATAATGTTGATAAAAGACAATTTACTTATGCCATTTTCAATATACTTTTGAAACATCTCAAACAATTCCGAAGAAGCTTGAAACTCAAAGACAAAAATGGGCAAAAAATCTCAGAATTATACAGGTATTCATTCTCCATGGTAACAAACAAGAAAAGTTGTGAATATTACATACATCAGATGATGAAAAAATTACTGATCAATTTCATTCATTGGGAATTATGGAATTCTATTCCATGCAAATTGGTCATATCAATCCTATCAAATAAAGCATCATACTTAATTGATTCATGTTCGAATTCTGAGTTTTTGAATTACTACATACTGAAAACATTGCTTTCTGAAGAACAAGCATTTGAACTGAAATTATCGCAATATACACATATTAAACTTAATTTAACACATATTAAAGGTCACCCAAAAATAAAAATTCTTGAGGAGGAAGAATGTACCTATGAAAGAAATTTGAGTTTGACAGAGGAAGAACAAAAAGCTGTAATAATTACACATGGAGATATTGAAAAGAATTCAAGCAAATATCCAAAATTAGAGAAAAATTGTGAAGCTATGGAACTGCCTGTCAAAACAAAAAATAACGTAGTTAAAGTTTATGAACCTAAAAGCACAAGTGAAAAATGGAATGAAACACTAGACTTAACATCTGTAACTTTGGGTGAAGATCCTTTGGCAAGCCCAAGTCAAAGGAAAAATCTTGCTGAAGCTATTGACATTTTGAAGGATGAAAAAATGGATGTAATTGCAGGAGAAGGCGACGCAACGGCCAACACTCTTCGCGACATAAAAGATTTCCAAGAGAACACCGTCAACACGGTCGTGAAACCGATGTCGCAGGCCACGTCTCAGGCTCTGCACAAAATCGGCGATTTTCAGGACGAGGCTGCTGGGATGGTGGAAGGACTGTTCGACCTTGGAATGGCTGGTATCCGGAGAGGTTTGAAGCTGACTGGCTTACAGGAAAACTCTTCGCAAGAAGGTATGATTACAGAAATTAAAGCCAGGTGTTCTCTGGTCAGTCCCGGTGCCACTAACAAAAAAGTCAGACCGCCTTCTAACGCTGAACTGGCCGAGGAATGTGTGTGGATGAATCCCTTGCAGACCAACGTTGACGATGATGTTCTAGCGGATAATGATGAAGTTGATCATGTACCTTCTATTCTGATGGATAGTTTAGAGTATGGCAGCCCTGATCCTGAGTACGAGGAAGGAGCAGATTTTGCAACCACCATAGCAAAACTTAGGTCTCTCCTTCAACAAAAGTCATCATCAGAATCAATTTCGACAACCCCTGTTGCAAGTCCCATGATGTCCGATAACAATAAATCTCTGTTGGATCTAGAGGAAGTCGACGGTTTTATCCCGAGTATCTATAAGATGTGCGCCAAAACTGCTACGGGCGTTTTCAACAATACCCTCAACACAATTAAAACCGCTTTACCCAGTACCGACGAAGAAGTGATAGCTTATGGGATCGAAAAATGGAATTTTGAAAATATTGAGGAGAAGGGGGCAACTTTATCATCAAGAATGCGCAAGTTGCTTTTAGAAAGGAAGGATTTTTGTACGATAGAAACAGCTTATGATGCATTTGACTCTCAAGAACCGGAAACAAAAGAATTTATATCGGATGTGTTTTTTGATGAGACAGAAGATTTTGAATCTAAAGTTCCATTAACAAGAACCTTCATTGATATAATTTGTGAATTGATAGCTGATTCTGATTCTTTTGCGTCTCAAGAACCCTTTATAAAATTTCTTCTATTAGTTTTTGGTAAATCTATGGATGAAATGATCATTTCGAAAGTCGAAGATCTTTTTGATAATTTATGTGTAACAGAAGTCCCAAAGAGCCTAGACTGCAAAGTATTAACTATGGACTTCGACGTTTATGTTGAATATTTGATATCAGTATTGCCAGATGCCGTGAATCTATTAGCAAGTCATTCCACACTTAAAGATGCACTAAATAACTTGATTTTATCCATTCAAATCGAAAAATGTAATAAAGATGTTATTTTACAAATATTCGATTTTATGAAAAAAATGTCTTCTGATGAACTTGAAATTAAGAAACAAAAATTAACATGTGATCATTCAGTAGATAGTAAATCTAAAGAAACCAAACAAGATAGTATGGTTGAGTTGAAATTTGATGAACTTGAAAGAATTCAACAACAGTTAAGTAGTTTCTGGAAGTATGAACCCATTAGAAAGAGTGTGGATCTGAGAACCTTGAATGTCCCAGTAAAGCAAATTGTAGAGGTTTTGGAAAAAAATGACCTAAAGTGTGAACGTATTAAGAAAGCAGAACAATCTCAATCTGACCTCATATCAAGCGTTTATGAAGGTGGCGCTAGAACTTGGGAATGCACCTACGATTTACTGAATTATATAGAAAATGAGAAAATGTATTTCCGTGATAAAAAAGTCCTAGATTTAGGATGTGGTACAGGATTGGTTGGAATAATGTGTTTATCTAGGCGAGCTACATGTCATTTTCAAGATTTTAATGATGAAGTTTTGAAATACATAACTTTTCCTAATGTCAAGGAAAATGTATATTATTTTCCAGAAAACAATTTCACCTCTTGTAAATTCTTATGTGGAGATTGGATTGTTTTTTCGAATTTTTGGCTGGAAAATTATCCTAAAGAAAAGTTTGATTATATTTTCACAAGCGAAACAATTTACAAGGAAGACAATTATCACAAGCTGCATTCTGTTTTTGAAGACTTATTAAGTCCACAAGGCAAAATGTATCCTTTTATTTTTAAGGTCATTGGTTATGATTTCTTAAATTTCATGAGAAGGTGA
- Protein Sequence
- MGECYNYSWENPTSFIEEGEIIYDAEEILPVNTEEITCDTQSTDTSLKHSESERDLQEEKLYFSSDDIFTKQLPNENEYLVLPMEDQVIEETVIEQWIGDSTQEIVSNELTTVEDNQYQVPLQQDEYITLRPYPCDFCNKRFRSKTNLTNHLSSHQNTHDYYECNECGLGFININELLGHKKIHENESKFSIDNSIQYLACMHCAEGFFSQKELDSHLKLHEAKPPSTCLKCGLDFINSRSLMEHRRRAHGFKDDRHKVRLKQKNKFGTYSCITCGKSFCRQDDLKRHQQNHIDDVVNDPESGFTCRVCCETFAEPLDLLAHAEEHARGFEYSCMVCSENFIDEETCAVHVKEQHPEEEGLHCSKCPRIFYDISRLEKHLLSHKDESLMNNVHDQTTNRFKNIGKLSDQQFSCQECGKRFATRSSQQIHMRIHTGERPYGCSFCHKAFTDGGTLRKHERIHTGEKPYACVICPKAFNQRVVLREHIRSHHSGPDPSCSDSMTPFRCTICSDMFSESQDLIVHVIHHCDINTAMKRKPKAGPRKYVRRSKLKSQKVQEQDEYDFQEENEEDEHHQQSGTMPNYEIDMDVNQTQDMRNTLSEHEYEDMDVDQEMSHSSTPILELPEMENREELRDTSVVTSRAKMIHTEKKPKINPVETRGRKNKKNTVREFLEGVRPRTKNVTYPVQEQSKPSIATFPPRNSRKRRKNPRFQEEFYSDHTESLDDSEEQIEYNVPEKRARRISLRKSNIGDAEIPEKTSKLKEEHSIGEFSFKQEFEQCEQQIVYETPDLYEIPECHSETIVKDEASEYANIISPSKPEDQRDVEVQDYSVQHEIIDPLLELAEISMQHAKSVNKCDMFWVTVTFIRKLFLKNQLLDWKIFEEKNIISTHYNTEENTTNQLSKDVVNQFIKIWYDEISIDDKFPTESGLFIKNTLVSINEALNNVDKRQFTYAIFNILLKHLKQFRRSLKLKDKNGQKISELYRYSFSMVTNKKSCEYYIHQMMKKLLINFIHWELWNSIPCKLVISILSNKASYLIDSCSNSEFLNYYILKTLLSEEQAFELKLSQYTHIKLNLTHIKGHPKIKILEEEECTYERNLSLTEEEQKAVIITHGDIEKNSSKYPKLEKNCEAMELPVKTKNNVVKVYEPKSTSEKWNETLDLTSVTLGEDPLASPSQRKNLAEAIDILKDEKMDVIAGEGDATANTLRDIKDFQENTVNTVVKPMSQATSQALHKIGDFQDEAAGMVEGLFDLGMAGIRRGLKLTGLQENSSQEGMITEIKARCSLVSPGATNKKVRPPSNAELAEECVWMNPLQTNVDDDVLADNDEVDHVPSILMDSLEYGSPDPEYEEGADFATTIAKLRSLLQQKSSSESISTTPVASPMMSDNNKSLLDLEEVDGFIPSIYKMCAKTATGVFNNTLNTIKTALPSTDEEVIAYGIEKWNFENIEEKGATLSSRMRKLLLERKDFCTIETAYDAFDSQEPETKEFISDVFFDETEDFESKVPLTRTFIDIICELIADSDSFASQEPFIKFLLLVFGKSMDEMIISKVEDLFDNLCVTEVPKSLDCKVLTMDFDVYVEYLISVLPDAVNLLASHSTLKDALNNLILSIQIEKCNKDVILQIFDFMKKMSSDELEIKKQKLTCDHSVDSKSKETKQDSMVELKFDELERIQQQLSSFWKYEPIRKSVDLRTLNVPVKQIVEVLEKNDLKCERIKKAEQSQSDLISSVYEGGARTWECTYDLLNYIENEKMYFRDKKVLDLGCGTGLVGIMCLSRRATCHFQDFNDEVLKYITFPNVKENVYYFPENNFTSCKFLCGDWIVFSNFWLENYPKEKFDYIFTSETIYKEDNYHKLHSVFEDLLSPQGKMYPFIFKVIGYDFLNFMRR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -