Basic Information

Insect: Harmonia axyridis
Gene Symbol: Smc5
Assembly: None
Location: chr7:18284908-18301858[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00016 0.014 16.3 0.6 2 23 1265 1286 1265 1286 0.97

2 14 5.3e-05 0.0047 17.8 1.8 1 20 1292 1311 1292 1314 0.94

3 14 4e-05 0.0036 18.2 3.0 1 23 1320 1342 1320 1342 0.98

4 14 1.8e-05 0.0016 19.3 4.3 1 21 1348 1368 1348 1370 0.95

5 14 5.2e-05 0.0047 17.8 4.6 1 23 1376 1398 1376 1398 0.99

6 14 0.0003 0.027 15.4 5.5 1 23 1404 1426 1404 1426 0.97

7 14 3.1e-06 0.00028 21.7 5.8 1 23 1432 1454 1432 1454 0.98

8 14 1.9e-07 1.7e-05 25.5 2.7 1 23 1460 1482 1460 1482 0.98

9 14 0.00014 0.013 16.4 6.7 1 23 1488 1510 1488 1510 0.97

10 14 0.00025 0.023 15.7 7.0 1 23 1516 1538 1516 1538 0.98

11 14 2.2e-05 0.0019 19.0 7.1 1 23 1544 1566 1544 1566 0.97

12 14 0.00033 0.029 15.3 0.2 1 23 1572 1594 1572 1594 0.97

13 14 0.051 4.6 8.4 5.1 1 23 1604 1626 1604 1626 0.98

14 14 4.3e-07 3.8e-05 24.4 1.0 1 23 1632 1654 1632 1654 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00016	0.014	16.3	0.6	2	23	1265	1286	1265	1286	0.97
2	14	5.3e-05	0.0047	17.8	1.8	1	20	1292	1311	1292	1314	0.94
3	14	4e-05	0.0036	18.2	3.0	1	23	1320	1342	1320	1342	0.98
4	14	1.8e-05	0.0016	19.3	4.3	1	21	1348	1368	1348	1370	0.95
5	14	5.2e-05	0.0047	17.8	4.6	1	23	1376	1398	1376	1398	0.99
6	14	0.0003	0.027	15.4	5.5	1	23	1404	1426	1404	1426	0.97
7	14	3.1e-06	0.00028	21.7	5.8	1	23	1432	1454	1432	1454	0.98
8	14	1.9e-07	1.7e-05	25.5	2.7	1	23	1460	1482	1460	1482	0.98
9	14	0.00014	0.013	16.4	6.7	1	23	1488	1510	1488	1510	0.97
10	14	0.00025	0.023	15.7	7.0	1	23	1516	1538	1516	1538	0.98
11	14	2.2e-05	0.0019	19.0	7.1	1	23	1544	1566	1544	1566	0.97
12	14	0.00033	0.029	15.3	0.2	1	23	1572	1594	1572	1594	0.97
13	14	0.051	4.6	8.4	5.1	1	23	1604	1626	1604	1626	0.98
14	14	4.3e-07	3.8e-05	24.4	1.0	1	23	1632	1654	1632	1654	0.98

Sequence Information

Coding Sequence: ATGTTCCAGCCTGGTTCAATCAGACGAATACAAGTGAAAAATTTTGTGACCTATTCATATGCAGAATTTTATCCTGGTCCTCATTTAAATATGATAATTGGCCCCAATGGTACAGGAAAATCTACTATGGTAGCTGCCATAATTCTGGGATTAGGAGGTAGTCCTAAAACAGTGGGGAGAGGCACAAAAATTAGTGAATATGTGAAACATGGTTGTGACAATGCAACCACAGATATTCATCTGCAGGGAAATAGTGACAATAGTTTCTTGCGAATAACAAGAAATTTTGATATCAATGAACGAAATGTATGGTCTATTAATGGAGTCAAAAAAAGTTCCAAGGAAGTTCTCGAAGTCATAAACACTTACAATATTCAAGTGAATAATCTTTGTCAGTTCCTACCACAAGATAGGGTGCAGGATTTTGCAAAAATGAATAAGCAGGAGCTGCTCAAAGCTACACAACTAGCACTTTGCAGAGAAGATTTGATTGAAAAACAACAGAAATTAATTGATAGTAAAGATAAGTATGCAGGAATTAGTACTTCCTTGGAAAAGAATGAACAAAAGTTAGTTCAAGCTAAAGAATCTAATGCTAGATTAGAGGTGAAAGTAGAAAGTTTCAACAAGAAAAAAAAATATTTAGATAATATTCAAGATATTGAAAGAAAGATAGCATGGTTAAGGTTTGAACAGTTAAAGGAAGAAGTGGATGAAGTAAAGAAAGATAAAATTGAGGCTACACAAGCATATGAAAAATATAAAGCCTTGGGGAAACCTATGGAAGATGAGATAAATAAGGCCAAAAATAACTCTAAAGTTTTGACAAATATACATTCTAATCTTATGAAAACAAAATGGGATACAGAAAATCGTTTGGAAGCAAAATATGATAGACTAGATTTGTATAAACAATCTATTCAGTCTGTTGATCAAGAAATGAATGTCAAGTTGGATGAGTTTTCTGAGCGTGAATCTGAAATAAATTCAACAATGGAGAAAATTAAAGTGCTAGAAAATAATCTAAAGAAATTGATGGAAAAATATCAGAATGATCAAGAGGTTCATCACAAATTGAAACAAATTAGTTCTGAAATCAATTTGATGTCTTCCAAAGAGAGAAAGGCAGAACAAGAAAAAGATCAGGTTCTTTTTAAAAAAAGAAATAATCAAGCTGAATTGAATATGTTGCATAATGAATTAAAAAATCTAGAAGATGTAAAAAGTCAAAGGTTCCAAAAACTTTGTAAGTTGAATAGAGGAGTCTATGACGCTGTTCTATGGCTTAGAAATAACAAGCACCTGTTCAAAGGTGAAGTATGTGAGCCAATGATGTTAGAAATTAACATACTAGATGCCAGAAATGCCATATTCTTAGAAAACATCATTTCAAAAAGAGATAGACTGGCATTCACTTGTGAAAAAAAAGAAGATATGAATCTATTGATTCACTGTCTTCGCAATCAACAAAACTTGTCTGTTAATGTTCTCCATTCCAACCGTGATATAGACATGAGCAATTATCAGCCGAATATACCAATAGAACAATTGAAGAAGTTTGGCTTTTATGCTTACATCGATAGCTTGTTAACTGCCCCCAAATTAATTATGAACTATTTATATAAATCATATAGGATACATGATATTCCAATTGGAAATACAAAAGTTGATCAGTATTTTGAAAATGTTCCCAACTCCATTCGGCTGTTTTTCAGTGAAAGAACAAGATATGCTGTGAAATTTTCTGCCTACACTGGTGCTAAAATTACCTCACAAAATGTAATTGCTCCGAATCATACTTTATCAATTTCAGTCGATATTGTAAGACTTGAAAATTTAAAAGGTGAAATCCAGCACAAGGAAGAACTTTATGCAAATATTGACAATGAAATAAAGAATTATGACAATGAGATACTTAATTGCCGAAGCAGAATTACAGAATTACAAGCTGAACAGAAAGTGATAACAGATTTGAAACAGCATATTCAGGCTGTAGGATCCAGATATAGTGCAATGAAGAAAAAAATTGAGAAATTGCAGCAGGCTAATACAGATAGGGACAGCGTGAAAGAAGAAGCCGCGCAAAAGATAAAGGGTATTGTTAAAGAAATGGTATTATTTCAAAAAGAGATTTTGTCAACATTCATATCCTGTAAAGAGTTGTCCATAAAATCAGCAATAAGTTTTAAAAAACTTGAGGCAGCTAGAAATAAGGCTTCATATTTAGAGCAGAAGTTCCGAGACACAAAAAGACAATGCGATGAAGCTGAAGAAGTGTTGAATGCTGTAAAAGAAAAGTATTTTAATATGGTTGTACAAGGCAAAGCAGCTTTACAGAAGGCTAAACAACTCTCTAAAGGTTTTACACCTGATGATGAGGGTTTCATTGAATTCAAACAAAAATATGATAAACTTTCTAGTGATGTGAAAGCTCTACAACAGGAGAAAGATCAGATTTTATTAAAGATTGATTGTTTGAAAATCGCTGATGACGGTGAACTAGAAGAATATGAACAAAGAGAGGAATTAATTAGGACATTAGAGAGAGAAATAGATGAAAACAACAATGAATTGAATAAAATGAAGTCGCAAATGGAAAAAATTGAAGAAGATTGGTTATTGCCTCTAGGAAATCTAATAAATGAAATCAATATCAAATTCTCTAATGCGTTCAACAGAATGAAATGTTCTGGTGAATTGGCCATTTGGACAGAGAAAACTATTGAGGGAATAGCAAATAAAGTTCATGATCCTATAAGCTTGGTCACAATTAAAGGTAATAAACCCTTTTCTTTTTCTGAAGTTTCGTTTAACGATGAAGCTATGCTGTCTCAACATGGGCTCATGCCAACAGATCCTTTATTGATACCTCAACACTCGCAAATTCCTGTCAGTATTGCCACATCACAAGGTGTTGCAAGTTTAGCTATTCCAACTGGAGCTATGCATATTGATGGTCAACATAATCATCCATCTTTAGCTCATCATTCTCAGCAGCAATCTGACATGTCTAATCAACAAAATCAAATTAGAGAGATGTCCCAACATCCAACACATTCATCCCACTCTCAACATTCACAGCAGCAGAATATGGTGCAAGTACAGGTGCAGGATAATTTGGTATCAGTTATTGAAGACAATAAAGATCATAAGGAGGCGATAGCCAATCATATTGTACAAGCTCATGCTCATGCCCAAGCACAACTTCATATCAATGAAAACCATCATATGAACCATCAAGCTCTCACAGTACAACAGTTACAGCATCAAGTTCAACAAGTATTGGATAATGTGGTACGTTTGGAAAATTCTGTAGAAAACAATCAGAATCAGTCCAACAATGATGTCCATATGAACGAAAATATTCAGATAGTGAAAGATGAAAAGAACCAACCTCAGCAACAGAACTGCAAAGTTTTACCAGCCCAGTTTGGTCTTCAGAATTTGAAAGATAATCTAATGGATGTTCGGACATCTGACGGTTCAATTTTAAAAATATCAGCAAATGTTCAAGAACAAGAATTAGTTAAAACTTTAGGTGTGGAAATGGTACAAAATATGTACAAGGTTAATGTCGATGACCTAAACCAACTTCTGGCATATCATGAAGTTTTTGGAAAGCTACAGGGGGAACTACCTTCAAGTGGTGCGCAAGGCATAATTCAAAGCACAGGGACCAGTGTAGGACTACAGAATCAGGGTTCTAATGCGACAGTACAAGCTAAGGATGAACAAGAAGCATCAACTAGCAATAATATTGAGAATGGACCTAGTATCATCAATGGTAGTAATGTGTGTGACTTATGTGGAAAAATGTTTCAATTCAGATACCAGTTGATTGTTCATAGGCGTTACCATACTGAGCGAAAACCTTTCACATGCCAAGTTTGTGGTAAGGCCTTCACCAATGCCCAGGAGCTTACACGACATGGAAAATGTCATTTGGGAGGTAGCATGTTCACTTGTTCAGTTTGTTTTCACGTGTTTGCTAACAACCAGTCATTGGAAAGACATATGAAAAGGCATTCCACTGATAAGCCTTACAACTGTTCGATATGTGGAAAATCATTTGCAAGAAAGGAACATTTGGAAAACCATACAAGATGCCATACAGGCGAAACCCCTTACCGATGTCAGTATTGTGCTAAAACCTTCACAAGAAAAGAACACATGGTTAACCACGTTCGTAAGCACACTGGAGAGACTCCACACAGATGCGACCTATGTAAGAAATCGTTTACAAGAAAGGAACATTTTTTGAATCACGTTATGTGGCATACTGGAGAAACTCCCCATCAGTGCAGTATCTGCAATAAGAAGTATACGAGAAAAGAACACTTGGCCAATCACATGAGGTCCCATACAAATGACACTCCCTTCCGATGTGAAATATGTGGAAAGTCGTTCACACGGAAAGAGCATTTTACAAACCACATAATGTGGCACACAGGGGAGACACCGCATCGATGTGATTTTTGTTCCAAAACTTTTACGAGGAAGGAACATCTTTTGAATCACGTGAGACAGCATACAGGTGAATCTCCACATCGTTGTGACTTTTGTCAGAAAACTTTCACCCGCAAGGAACATATGATTAACCATCTTCGACAACATACTGGAGAAACTGCCCATTGTTGCAATGTATGCTCCAAACCCTTCACGAGGAAAGAACATCTCATTAATCATATGAGATCTCATACAGGAGAGAGGCCTTTCGCTTGTGGTGAATGTGGAAAATCCTTCCCATTGAAAGGTAATCTACTGTTCCATCAAAGGTCGCATAATAAAGGTGCGCAGGCTGACAGACCATTCCGTTGCGATTTGTGCGATAAGGATTTCATGTGCAAAGGACACTTAGTTTCTCATCGTAGATCGCACAGTGTGGAAAGGCCCCATGTGTGTCCAGATTGTGGAAAAACCTTTGTTGAAAAGGGTAATATGATGAGACATCTACGGAAACATGCTTCAGACAATGCGCAACTCAATTCTTCGCAATCTCTGACCTCTCAGAGTCAACCTCAATCCACCAATTTGCAAATACCGCAAGTTGGTCAACCCAATAGTCCTCCATCAGGGGGAACTATTGTAACACAGCAACAACAGCAAGGACCTCCCCCACATTTATCAATGCATGCTCCACCTCCCCCTGGAGCTCACCCTGTCTTAGTGCCTGCACCCAACGGTAATGTACTGGCCTCTTACTAG
Protein Sequence: MFQPGSIRRIQVKNFVTYSYAEFYPGPHLNMIIGPNGTGKSTMVAAIILGLGGSPKTVGRGTKISEYVKHGCDNATTDIHLQGNSDNSFLRITRNFDINERNVWSINGVKKSSKEVLEVINTYNIQVNNLCQFLPQDRVQDFAKMNKQELLKATQLALCREDLIEKQQKLIDSKDKYAGISTSLEKNEQKLVQAKESNARLEVKVESFNKKKKYLDNIQDIERKIAWLRFEQLKEEVDEVKKDKIEATQAYEKYKALGKPMEDEINKAKNNSKVLTNIHSNLMKTKWDTENRLEAKYDRLDLYKQSIQSVDQEMNVKLDEFSERESEINSTMEKIKVLENNLKKLMEKYQNDQEVHHKLKQISSEINLMSSKERKAEQEKDQVLFKKRNNQAELNMLHNELKNLEDVKSQRFQKLCKLNRGVYDAVLWLRNNKHLFKGEVCEPMMLEINILDARNAIFLENIISKRDRLAFTCEKKEDMNLLIHCLRNQQNLSVNVLHSNRDIDMSNYQPNIPIEQLKKFGFYAYIDSLLTAPKLIMNYLYKSYRIHDIPIGNTKVDQYFENVPNSIRLFFSERTRYAVKFSAYTGAKITSQNVIAPNHTLSISVDIVRLENLKGEIQHKEELYANIDNEIKNYDNEILNCRSRITELQAEQKVITDLKQHIQAVGSRYSAMKKKIEKLQQANTDRDSVKEEAAQKIKGIVKEMVLFQKEILSTFISCKELSIKSAISFKKLEAARNKASYLEQKFRDTKRQCDEAEEVLNAVKEKYFNMVVQGKAALQKAKQLSKGFTPDDEGFIEFKQKYDKLSSDVKALQQEKDQILLKIDCLKIADDGELEEYEQREELIRTLEREIDENNNELNKMKSQMEKIEEDWLLPLGNLINEINIKFSNAFNRMKCSGELAIWTEKTIEGIANKVHDPISLVTIKGNKPFSFSEVSFNDEAMLSQHGLMPTDPLLIPQHSQIPVSIATSQGVASLAIPTGAMHIDGQHNHPSLAHHSQQQSDMSNQQNQIREMSQHPTHSSHSQHSQQQNMVQVQVQDNLVSVIEDNKDHKEAIANHIVQAHAHAQAQLHINENHHMNHQALTVQQLQHQVQQVLDNVVRLENSVENNQNQSNNDVHMNENIQIVKDEKNQPQQQNCKVLPAQFGLQNLKDNLMDVRTSDGSILKISANVQEQELVKTLGVEMVQNMYKVNVDDLNQLLAYHEVFGKLQGELPSSGAQGIIQSTGTSVGLQNQGSNATVQAKDEQEASTSNNIENGPSIINGSNVCDLCGKMFQFRYQLIVHRRYHTERKPFTCQVCGKAFTNAQELTRHGKCHLGGSMFTCSVCFHVFANNQSLERHMKRHSTDKPYNCSICGKSFARKEHLENHTRCHTGETPYRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDLCKKSFTRKEHFLNHVMWHTGETPHQCSICNKKYTRKEHLANHMRSHTNDTPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCDFCQKTFTRKEHMINHLRQHTGETAHCCNVCSKPFTRKEHLINHMRSHTGERPFACGECGKSFPLKGNLLFHQRSHNKGAQADRPFRCDLCDKDFMCKGHLVSHRRSHSVERPHVCPDCGKTFVEKGNMMRHLRKHASDNAQLNSSQSLTSQSQPQSTNLQIPQVGQPNSPPSGGTIVTQQQQQGPPPHLSMHAPPPPGAHPVLVPAPNGNVLASY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -