Basic Information

Insect: Halictus rubicundus
Gene Symbol: ZFX
Assembly: GCA_028454235.1
Location: CM052177.1:6793211-6797677[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.2 94 3.7 0.1 3 23 15 35 14 35 0.94

2 14 0.00076 0.062 13.7 2.2 2 23 991 1013 990 1013 0.96

3 14 0.014 1.1 9.8 0.1 2 23 1026 1047 1025 1047 0.97

4 14 1.6e-05 0.0013 19.0 2.3 2 23 1050 1071 1049 1071 0.97

5 14 0.012 0.94 10.0 0.3 1 23 1077 1099 1077 1099 0.95

6 14 2.3e-05 0.0019 18.5 4.5 2 23 1106 1127 1105 1128 0.95

7 14 0.1 8.3 7.1 3.7 5 23 1141 1159 1140 1159 0.97

8 14 2.1e-05 0.0017 18.7 1.5 3 23 1166 1187 1165 1187 0.97

9 14 0.0094 0.77 10.3 0.3 2 23 1203 1223 1202 1223 0.97

10 14 6.2e-05 0.0051 17.2 0.7 1 20 1229 1248 1229 1251 0.92

11 14 7.7e-05 0.0063 16.9 2.7 1 23 1259 1281 1259 1281 0.99

12 14 0.0022 0.18 12.3 3.2 1 23 1287 1309 1287 1309 0.97

13 14 3.9e-06 0.00032 20.9 3.9 1 23 1315 1337 1315 1337 0.99

14 14 0.0014 0.11 13.0 6.3 1 23 1343 1365 1343 1366 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.2	94	3.7	0.1	3	23	15	35	14	35	0.94
2	14	0.00076	0.062	13.7	2.2	2	23	991	1013	990	1013	0.96
3	14	0.014	1.1	9.8	0.1	2	23	1026	1047	1025	1047	0.97
4	14	1.6e-05	0.0013	19.0	2.3	2	23	1050	1071	1049	1071	0.97
5	14	0.012	0.94	10.0	0.3	1	23	1077	1099	1077	1099	0.95
6	14	2.3e-05	0.0019	18.5	4.5	2	23	1106	1127	1105	1128	0.95
7	14	0.1	8.3	7.1	3.7	5	23	1141	1159	1140	1159	0.97
8	14	2.1e-05	0.0017	18.7	1.5	3	23	1166	1187	1165	1187	0.97
9	14	0.0094	0.77	10.3	0.3	2	23	1203	1223	1202	1223	0.97
10	14	6.2e-05	0.0051	17.2	0.7	1	20	1229	1248	1229	1251	0.92
11	14	7.7e-05	0.0063	16.9	2.7	1	23	1259	1281	1259	1281	0.99
12	14	0.0022	0.18	12.3	3.2	1	23	1287	1309	1287	1309	0.97
13	14	3.9e-06	0.00032	20.9	3.9	1	23	1315	1337	1315	1337	0.99
14	14	0.0014	0.11	13.0	6.3	1	23	1343	1365	1343	1366	0.96

Sequence Information

Coding Sequence: ATGGATCTTACAAACAATGGAACATCAGGGAGTGCAGTGGCTTGTCCAGTTTGTACCCTCTATTTACGCGAGGGTATCAGCTTGCAAAGACACTTGGACACTCATCCAAAGGAACAAGTCATCGAAGCTCTTATCAAAGCTAGTTCTAATTCCTCGCAATTGCAACAAACTCAGTTATCACCATCTGCGCCTCCGGCTTCTCCATCTGTACAATCGCCACAAAGTACACCACCAGTTGCACAGAATACTCATCTATCGACTCAGTCACCATATCCTATAGGACCAATCTTTGAATGTCCACCGCCGATCGGTACCGTGATGCCACCACAATTTGCTTCGTTCAGTTATCAACAGTTTGTGAACAATGGCACTATGATGATACCGCAATACGCAATGGCTCCTCAAGCTAATCAAATGATGCAAATGCTATATAATCCATACGGTATGTACCAACAACAACAAATACCAACCGTTCAGATGATCTCGCCAGTCACAACTATACCCAATACACCTAGAGGCAGGTCAATAGTAACTATGGCAGGGGAAACGAATGGCAGAACTGCCATTACTATACCTGTAAATAATTCCGAGCCAAAACAAATCTTACCTGAGATTTTGCCCGAATCGGAACAAGAACCTGAACAAGTGTTGCCAGATATCAATCTTCCAGTTTCACCACCATCATTAAATGAAGAGAACTCTATGCATCAAAATGAAAACGACACTAGTACAATTCAAATAGAAACTGATGAACAGGAGCCCTCTACCTCGGGCAACGAAAATCAGCACATTATTCAGGATGAATATAATAACATTCCGAGAACATTGACTATCACTTGTAATGTTGAGGATACCGGGGATGACAAAGTCGAAAGTGTGTTGCCTGATATTGATGAGGGTGATACTTCATGCATTGTTAATGTAGATGTTCAATGTAAACCTATGCAATATGAATCCTTGGATGCGCAAGAATATGTACACACGTACAAAGACGAAGATGATAATAATAAAGATAATATGCCCGAATCATCGCCAGTAGCAACACAAAAGGAAGCTGAAGAAACAACTACAGAGAAAGTTCCTTGCACAGAAGTAAATGAAACTGAAGGTACCTCATCTCAAACACCTGTAGAAGGTGCAACTAAAGATCCAGCTCAACCTGAAGTAGAACAATTAGAACGTCTTTTAATCACCATTATGGAAAATGAATTCAATGCTGAATCACATAAAAAATCTACTAATAAAAATGAGAAAAAGAAAGAAGGAGAGCCAAGAGAAGATCCCCCCTGTTCTCCCCCAGAAAGAGCAGAAAGTGTGATTCATGAAATAGCAGCTAACAGTTCCAGTGAATTTGAAACCAGTTGTAAATCCGATCTAGAATTAAAAGTTAGTGAAAGTTCAGAAATTGATATAGATAGTAAAGAAGATAAGAATTTAAGTCTTTCATATCGTTATAAAAACAGTTTTTCTGCACCTGCATCGCCTATGCCATTAGAAAGTCGTCGTTCGACTTACTCTGTTCGTTCGGTATTCGGTTCACATGAAAACCTTAATTCTTACCCAGTCGGTTTTGATGCAAACACATTGCAAGACGAAGAAAATGACGAAGATGAGAAAAATGAAACAGAAGACAACTTTGATGAAGCAGATATGGAAATAGAAGAAATCCAGAGTCCTCATACACCTTTCATTAGATATGGGGAGAACACAGACAATGTTAGATCGCATACTCCGTTATCTGTAAGCAGCGGTATCTCTGTATTAAGGGTCAGAAAGGATCTCAGTAAACCGTGTTCACCTGCTTCTGTGCATTCATTTTGTCACATAGATAATGGTATAAGTCATGATGAAGAAAGTAATATAGCAATGGATGCAACACCAGAAAAAGATCCTATTGATTGTTCTTCTATGGAACAAGATGTGAAAACAGATCAAACAGAAACCTTTTTGAATGAAACTGTTGAGAAGAAAATAGAAGGGAATTCAGCATATCAATCTGTAATAACTGAACATGTGAGCTCATTTCCCACAATTTCACAACAATCAACGTCATCGTCACATGAACCGTATACTAGTATACCAAATAAAAGTAATCTTGTAAATCTGTCAGAATCTATAGATGTTGCAAGTAGTTCTGACTCAAAGAGTTTCCATTCCTCTAAATCAATTATACAAAAACCATCAATGGAACTACTTAGTTTAAACGAAGATGCTCATGCAGGTCCAATGAATGTTTTTGAATTTGATGGGCTTCAGATCTTAGTTCCTAGTACATTTATAAGTGATTCTTCACAAAAAGCTGTTAGTGCAACCAGTCAGCAATCTATGGCAAGCAGTGAAGGTGGAATAGGCATAGACGAAGAAGTAAAGAGTGTTAATATGAGAGCTGATGAAACTATGCCACCAAGGGGTGAATTATCAGAACAGGAAAGCAACGGATGCACAGAACCGTCTGCTTGGCAGCTGTATGCTGGTCAGGAGTCATCACGTATGTCTACTTCTTATGACTTGATGGCCCGTGAGAGTTGGGAAGAATCTGAAGGATCAGACAATGAAATTAGTGGACCGTTATTAGACAGTAGATCTTTAGCTACACATTTCACATCGAGTTTATTCCTAGATCGAGACAGAAAAACTCCAACAAAACGAACATTCAAGTGTTATCATTGTCCCGAGATATTTGATTGTCCAAAAGAACGCAGAGTACACAGTACTACTACGCACAAAGAAGCTGGACCTAGTAGTAGCAGAGATTCCACAGATCAACCTGAGGTGAAAGATATCAAATTGCTAGATGGTCGTATGAACGCATTTGAGGATATTTTTGTACCAGGTTTACATGTTCAACAAGTTTATCATCAACAACCACTATTACATCAACTCCAACCACCACAATCATCGGATGTAACTGCAAAAGTAGAACCTGATCAAAAGATTGAAACCTTAGTGTTACCATCAAACATTGAGGTAGTTTGTACTCTGTGCAATCAACGATTTAGTAGTGAAAAATCGTTACAGCTACATCATAAAAGAGTACATCTTACAGAAACTTCAAAACGAGTTCGTGATAGTACCAAGTGTCAGATATGCCAAGAAGAGTTTCCCTCGGTTTTGTTGTTCAATGCACATCTGAAAATACATCCGTTAGAGTGTGGTCAATGCGGAAAGTATTTTTATAGGAAACAGAACTTCAAGTTACACATGAAACGACATTTAGGGATAAAACCGTTCCCGTGCACTGTTTGCGACAAAGCATTTTTAACAAAACAGAAGTTAGACGAGCATACCAACGGACATACTGGAAATGCACCTGTTAAATGTAATCTTTGCAATGAAACATTTCGTAGATATTCAAATTTGACTCAACACAAGAATAGACATCATCTTAACATAAAAAGGAAATTAAAGGATTATATATGTCACTGCGGTGAAGTATTCCATACAAAGAAAAAATTGGCTTGGCATAAAGAGACACACGACGACAAGCCCAAAGCGTGTACGTATTGCAATGAAAGATTTATTCATATGGCCAGTCTGACCAGACACATGCGTCGTGCTCACAACAGAAGATTCGTTCCGGATGCTCAAAGGGAGAGCGAAAACGTTGAATGTCCTATATGTAAGTGTATTTATTTGCGATCTTCCTTAGCAGTACATATGCGAGTACATAACGGGGAGAGACCATATGAATGTCAAGTTTGCTCCAAGGCGTTTAGTACTAAGTGGAACTTACAATTGCACAAATGGACACACGCTGCCCGTAGCACCAAACCTTTCAAGTGTAATCAGTGTAGTGCCGCATTTTACCGGCACAGCGATTATACCGCTCACATGAATTCTCATAGGAACGTGCGTCCTTATACCTGCAACTATTGCGGAGCGCAGTTTATACGAAAGTATAATTGTCTAAGGCATGTCAAAGAGCACGAAGAGAATAAAGCATACACGTGCGATGTTTGCAACAAAACATTTCATAGATCGTACTATCTGAAGGAACACTTGCGAGTACATTCGGGCGCCAGACCATATACATGTCATATTTGTGGGAAGTCAAGCGGTACGAAGTCGAACCATAACAAGCATGTTAGAATCCATCATGCGCGAGAGCCTGTAAATACCGAAAATTAA
Protein Sequence: MDLTNNGTSGSAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASSNSSQLQQTQLSPSAPPASPSVQSPQSTPPVAQNTHLSTQSPYPIGPIFECPPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTTIPNTPRGRSIVTMAGETNGRTAITIPVNNSEPKQILPEILPESEQEPEQVLPDINLPVSPPSLNEENSMHQNENDTSTIQIETDEQEPSTSGNENQHIIQDEYNNIPRTLTITCNVEDTGDDKVESVLPDIDEGDTSCIVNVDVQCKPMQYESLDAQEYVHTYKDEDDNNKDNMPESSPVATQKEAEETTTEKVPCTEVNETEGTSSQTPVEGATKDPAQPEVEQLERLLITIMENEFNAESHKKSTNKNEKKKEGEPREDPPCSPPERAESVIHEIAANSSSEFETSCKSDLELKVSESSEIDIDSKEDKNLSLSYRYKNSFSAPASPMPLESRRSTYSVRSVFGSHENLNSYPVGFDANTLQDEENDEDEKNETEDNFDEADMEIEEIQSPHTPFIRYGENTDNVRSHTPLSVSSGISVLRVRKDLSKPCSPASVHSFCHIDNGISHDEESNIAMDATPEKDPIDCSSMEQDVKTDQTETFLNETVEKKIEGNSAYQSVITEHVSSFPTISQQSTSSSHEPYTSIPNKSNLVNLSESIDVASSSDSKSFHSSKSIIQKPSMELLSLNEDAHAGPMNVFEFDGLQILVPSTFISDSSQKAVSATSQQSMASSEGGIGIDEEVKSVNMRADETMPPRGELSEQESNGCTEPSAWQLYAGQESSRMSTSYDLMARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCYHCPEIFDCPKERRVHSTTTHKEAGPSSSRDSTDQPEVKDIKLLDGRMNAFEDIFVPGLHVQQVYHQQPLLHQLQPPQSSDVTAKVEPDQKIETLVLPSNIEVVCTLCNQRFSSEKSLQLHHKRVHLTETSKRVRDSTKCQICQEEFPSVLLFNAHLKIHPLECGQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKRKLKDYICHCGEVFHTKKKLAWHKETHDDKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962003;
90% Identity: iTF_00183443;
80% Identity: -