Basic Information

Insect: Habropoda laboriosa
Gene Symbol: br
Assembly: GCA_001263275.1
Location: NW:285977-319725[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 4.5e-08 2.5e-06 26.8 1.8 1 23 637 659 637 659 0.98

2 8 2.2e-05 0.0012 18.3 2.0 1 23 665 687 665 687 0.98

3 8 1.4e-06 7.7e-05 22.1 0.3 2 23 696 717 696 717 0.98

4 8 4.5e-05 0.0025 17.3 0.1 3 23 725 745 723 745 0.97

5 8 1.4e-07 8e-06 25.2 3.0 1 23 751 773 751 773 0.98

6 8 2.4e-06 0.00014 21.3 0.7 1 23 779 801 779 801 0.98

7 8 5.1e-05 0.0029 17.1 7.5 1 23 807 829 807 829 0.98

8 8 6.3e-06 0.00036 20.0 1.0 1 21 835 855 835 856 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	4.5e-08	2.5e-06	26.8	1.8	1	23	637	659	637	659	0.98
2	8	2.2e-05	0.0012	18.3	2.0	1	23	665	687	665	687	0.98
3	8	1.4e-06	7.7e-05	22.1	0.3	2	23	696	717	696	717	0.98
4	8	4.5e-05	0.0025	17.3	0.1	3	23	725	745	723	745	0.97
5	8	1.4e-07	8e-06	25.2	3.0	1	23	751	773	751	773	0.98
6	8	2.4e-06	0.00014	21.3	0.7	1	23	779	801	779	801	0.98
7	8	5.1e-05	0.0029	17.1	7.5	1	23	807	829	807	829	0.98
8	8	6.3e-06	0.00036	20.0	1.0	1	21	835	855	835	856	0.95

Sequence Information

Coding Sequence: ATGATGGGAGAGGTGATCCGCGTTTCTGGGAGGACACCGGATGTCGGGGAGTTCCTCAAGGAGGCGATGCTGTCCCAAAGATTCGCTGATGTGGCTCTCTGTTGTCCTGGTGGACAAAGATTCCTGGCTCATCGTTTGGTCCTCTCTGCTGCCAGCCCTTATCTACAGGAAGTATTACTCGCTCACAGCAGAACGTCCACGCATTGTGAACCGATCACCGTGATCCTTGCAGAAGTGGAGGCACCAGAATTAGCTGCAATCCTTGGTTTCGTCTACACTGGAAGCGCCACTGTCCCTCGTCCTCGTTTGAACGCGTTCCTTCACGCTGCAGAGGCTCTGCACATCAGACTTCCGCCTGTTCCCGTCGTGATGACTTGTTCCCAGCCTGACTGTAAACAGGAAGACATCAAGGACGTGAAGATCAGCCCGAAGTACCTGCAGTGTGATCAGTATCCGTGCTGCGACCGCTGGTACCGTCCACGACGTGATCAAGATGGCGATTCCGCGAGTAAGGAGGAACCCTATCCGTCGATCGAGTCCTTGGAAACCGCAAGAGAAATCAGACCGCTTCCTGAATCGATGAACTTTGCCGGATCGCGATACAGCACGGCCAGATATTGCTCTACAACCTGGCCCGTTCCACCTTTCGCGAGCCACGCTCAGGAAAAGACGGTTCACGGTGTAGATCATGGTATAGATAAGGAGAGGATGGATCAGACGGACGTCACAAGGTATCAGCAGATCTCTGTGGTGCCGAGGATCGATAGAATTAGCGACGTTACCGTTGGACAGTCGGAGAACCTTCTTACTACATGTGAATCCTCCTTGAAGTCCCGCCAACAGGAGTTTTGCTTCTCCAGAGGCTCGTACGATCTTCACAGGCAATTGGATCCGTTAGAGATGAGGATGAAGGGTGATCAAAGTGGTATGCAGGTTAGAAACGAAGAGGATTGCTTAGGGAGGGATTTTTCCGGATACGACGGCTGTTGCGAGCAAGAGAGAAGCAACGGAGATCGACTGAGTGTGATTCGTTCTCGAGTAAGCTCCTGTCAGAGCAAGACTGTGTCTGTACAGTTACCTGGACGTGGTAAAGTCTACGAGAAGTCGGATTTTGGGGAGGATTTGACTTGCAGAGAGAGCTGTTTCGCTTGGAAGTCGCCTAAGAGACACGTGGCTAATAGAGTGATAGCTTCTCCGTGGAGGCAGACCATCAGGCCTTATCATTTGCCCAAGTTGCAGCCAATCGTGCTTCAGCCTCACGTCGAAGAGTCCGAAACCGTGGAAAATCTGCGTCCGCAGGAAGTCACGCGACCTCCACCTATTTCCACCAGCCCTAATCGTCAGTTCTCTAAAAGTTCTACGCCTAGCGATCACTATTATGGTGTCGAAGTTCCTACCACTCATGAAATTACGTACAACAATGATACGAGATTGTTGGAAGCTAATTCAACATTGTTACCAAGGCCTCAGGAATTTTATTCGCCTCAAATTGCATTACCAACGACCACACAGATGACTACGACAACTATTAATAACGATACCAGAAATACCGAAACGATTTTACAGTCGCAGAATCATGTAATTTCTACGACAACGAGGTGTTTAACAACTAGTACCGATAATGGACAGATGAATGTTAACAGGAAGAACAACTACTTTGGTCAAACGTTGCCTCAATCGCCGCAGAAGCCAGAGATCTCGCATCCTGTTAGTAGATTGTGCGATACGATCGAGTCGAACGATAAAGGAGATCGTTTTGTAAGTGTGGAACCTCAGAAAGTGGTAGAGAAAGAGGCGAGGATCGAGGATAAACTGGTTGAAGGAGTTGTTATCAAcagtgataataataataacgacgCGATCGTTAATCAAGATGCTGTTCAGCGTGGTAAAGGAATGCAAGAGAATCATAGGTGTGATCAGTGCGGAAAAAGCTTTGTTACCAGGGCGTCTCTGAAGGTGCACATCAGGACTCACTCAGGGGAGAAGCCTTTCCGTTGCGCCGACTGCGGCAAGCAGTTCTCCCAATTGCGCAACTACAAATACCACCGTAGCGTCCACGAGGGGACCAGGGAGTTCGCGGCCACCTGTCCAGAATGCGGCAAGTACTTCAACGACCGCGGCTACCTGAGCTCCCACATGAAGATCCACCGTAACCGGAAGGAGTACGGGTGTGCGGAATGCGGCAAGAGCTTCAATCAACGAGTCGCCTACAACATGCACGTTAGAATACACACAGGAGTGAAACCACATCAGTGTGAACAGTGCGGAAAGGCTTTTTCCAGGAAGATGCTACTGAAACAACATCTCAGAACTCATTCAGGAGAAAGACCTTATCAGTGCCAGGTTTGCCAGAAGGCATTCGCTGATAGATCAAACATGACTCTCCATACAAGACTACACTCTGGATTGAAACCTTATCAATGTACTCTGTGCTCCAAGGCATTCACTAAGAAACATCATCTAAAAACACATCTGAATTATCACACCGGAACTAAACCTTATTCCTGTCCGAACTGTGGACTAAGATTTTCACAGAGCAGTAACATGAGGACTCACTATAAGAAGTGTACCATTAACAATCCAATAGAAATGAAGAATTCACAATTGGAGGTTACAGTGATAGATTCGTCGAAAATTCCACAGACCAGGGTAATCTCCAGGACACCAGCAGACACTCTGACTCCGCCTAACTCTGACCAAGAATTAAGCATCCTAACTCCAATTTCCAAAAGCGGCGTGATAGAAGGTACAGGGACGTAG
Protein Sequence: MMGEVIRVSGRTPDVGEFLKEAMLSQRFADVALCCPGGQRFLAHRLVLSAASPYLQEVLLAHSRTSTHCEPITVILAEVEAPELAAILGFVYTGSATVPRPRLNAFLHAAEALHIRLPPVPVVMTCSQPDCKQEDIKDVKISPKYLQCDQYPCCDRWYRPRRDQDGDSASKEEPYPSIESLETAREIRPLPESMNFAGSRYSTARYCSTTWPVPPFASHAQEKTVHGVDHGIDKERMDQTDVTRYQQISVVPRIDRISDVTVGQSENLLTTCESSLKSRQQEFCFSRGSYDLHRQLDPLEMRMKGDQSGMQVRNEEDCLGRDFSGYDGCCEQERSNGDRLSVIRSRVSSCQSKTVSVQLPGRGKVYEKSDFGEDLTCRESCFAWKSPKRHVANRVIASPWRQTIRPYHLPKLQPIVLQPHVEESETVENLRPQEVTRPPPISTSPNRQFSKSSTPSDHYYGVEVPTTHEITYNNDTRLLEANSTLLPRPQEFYSPQIALPTTTQMTTTTINNDTRNTETILQSQNHVISTTTRCLTTSTDNGQMNVNRKNNYFGQTLPQSPQKPEISHPVSRLCDTIESNDKGDRFVSVEPQKVVEKEARIEDKLVEGVVINSDNNNNDAIVNQDAVQRGKGMQENHRCDQCGKSFVTRASLKVHIRTHSGEKPFRCADCGKQFSQLRNYKYHRSVHEGTREFAATCPECGKYFNDRGYLSSHMKIHRNRKEYGCAECGKSFNQRVAYNMHVRIHTGVKPHQCEQCGKAFSRKMLLKQHLRTHSGERPYQCQVCQKAFADRSNMTLHTRLHSGLKPYQCTLCSKAFTKKHHLKTHLNYHTGTKPYSCPNCGLRFSQSSNMRTHYKKCTINNPIEMKNSQLEVTVIDSSKIPQTRVISRTPADTLTPPNSDQELSILTPISKSGVIEGTGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00230793;
90% Identity: iTF_00761084;
80% Identity: iTF_00761084;