GBI_14744-RA
Basic Information
- Insect
- Gryllus bimaculatus
- Gene Symbol
- topi
- Assembly
- GCA_017312745.1
- Location
- Scaffold149:3165284-3199576[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 3.6 2.1e+02 3.3 0.1 3 19 460 476 458 478 0.82 2 19 0.05 2.9 9.1 0.5 1 22 506 527 506 530 0.89 3 19 0.14 8.3 7.7 0.3 1 23 600 622 600 622 0.95 4 19 9.1e-05 0.0054 17.8 1.2 1 23 694 716 694 716 0.98 5 19 0.00056 0.033 15.3 0.9 1 21 720 740 720 741 0.94 6 19 0.0023 0.14 13.3 0.8 2 23 792 813 792 813 0.95 7 19 0.015 0.86 10.8 6.7 2 23 819 841 818 841 0.96 8 19 0.00017 0.0098 16.9 1.2 1 23 847 870 847 870 0.97 9 19 0.0043 0.25 12.5 0.9 1 23 907 930 907 930 0.97 10 19 0.0017 0.1 13.8 3.9 1 23 942 965 942 965 0.97 11 19 0.0094 0.55 11.4 5.4 1 20 1011 1030 1011 1033 0.95 12 19 0.00045 0.026 15.6 5.8 1 23 1039 1062 1039 1062 0.96 13 19 0.00078 0.046 14.8 3.7 1 23 1074 1097 1074 1097 0.97 14 19 0.54 32 5.9 2.9 2 23 1151 1173 1150 1173 0.92 15 19 0.04 2.4 9.4 1.9 2 23 1188 1209 1187 1209 0.94 16 19 6.9 4.1e+02 2.4 0.1 5 17 1253 1265 1252 1266 0.88 17 19 0.00038 0.022 15.8 0.5 5 23 1287 1305 1285 1305 0.97 18 19 0.0055 0.32 12.2 3.0 1 23 1312 1334 1312 1334 0.97 19 19 0.00015 0.0088 17.1 2.8 1 23 1355 1377 1355 1377 0.98
Sequence Information
- Coding Sequence
- ATGAACGTACATGAACTGTGTTTTGTGTCTGCCAAGGAAATGGATGTTTCTAATTGTGAAAGTGAAGAGGAGGAACTTCCTAGACCTGAAACTGTAACAGTAATACAAGATGAATTTGCCGAAGATACTGATCCCTTTGTATCACATAACTCAGATCCACTAAGTGTTGATCCATTGTCTTTGGAGCGTAGTATTGAACCTCCTCGTCAGCCTATTAAGGAAGAGCAGGGAGATATTTCGGAGGTATGTGTCAAGATTGAACTTTCTGATACTGAGGATGAGATTTCCAATGTTTCAATTTGTCACATGCCTGAAGATGATGGCTATCGCAGTGGCAATGATGAGGATGTTTTACACAAAAATCAGCCAAAGAGCAATCGCATAAATAATGCTCAGACAAATATTAATGAATCAGTTGCAAATAAATTAAATGAAAAATTAGGTGAGGTAGAAAATGCCAATGTTAAGAAAGGAGCTTCAGCTCAAGAAGGGAACTCAAAGACGAGAAGATCACAAGGTAATGGAGTTTCAGAAATACAAGCTAATGTTTGCTCTAACATTGACCTATGTTACCCAGAAGTTGGGAGTGGAATTTTGGACCGATCCTGTGGTTCAGAAGTGGAAGTTTCTCAGAATCAGCAAAAAAGAACAACAAAAGAAAATAATGTTAATGGACCAAAGGAAACTACTTGCCTGGAGAGAGATAACTCAAATACTTTGGGTAGTCCATTTGCAGAAACCAGACAAGCTCTTGCTGGGAATTCCTTCAAAACCTCTGTTAATTTTTCCAAACATAAAGAACCGAAGGAAAGAATTGAAGAAACTGAAAAATTGTTGCCTCTTTGCAACATTGAAAGAAAATTAAAAGTTGTGCTTACTAGATGTAAAGAAGCAGAAATGCTTGCGTCTTCCATGAAATTAGCTGGACAGCGTTTGAGTGAGAGGAAACATAATAATGATGTACCAGCCATTAATCTTAGTCCAACTAGAGGGAATGAAATTAATTCTGTGAAAGGCTCCAGAGTACATGAGATGCCAGAGAAGAAAATCTCAATATTGAAAATTGGGAGGAATAGAGATGCTAATGGCTGGAGGGTAATGTCGGCTGGGGAAAAAGTTTCCAGTAAACTTCGAACGAAAAGTGCAAAAGTTCAGAAAACAGTAGCAAGTCAAGATCTTGAAAATGCATTGGTGCCTGGAGATGAATCTGCATCTTCAGTTAGCAGAGATAAGACAATAAGCGGTAAAGAAGTGCAAGATTTCTCGGAAAGAAGAGATGAGTTGGGAGAACACCAAACTGCTGATGGAACTGGTGGTTCTGTGAGAAAATTTCTATTAGAAAACAGCAGTGAAGGTGCTGTATTGAAGCCATGGAGTTGTATTATTTGCCACAAAAGTTTTGACAATCCTTTTGCAATGAGTGGCCACACTGGACATTGCAAACGTAGGCTTAAAAACGAAAGGATCTGTCGTACTCTCACTGATTTAAAAGAACATTTGCAAGTAGTGGATAGGTATAAATGTGAAATATGTCAACAAAAATTTGCATCAGTGAAGGGTATGAAATTGCATAAATCTCGTGTGGGGCATAATCATGATTTGAAAGAGAATGAAAAGCATTTAAACTTGAATACACCTGTGGCACAATTACAAGACCTCCAGAAATTTGAAGAGAAACTTCGAAACAATCCTCATACACCAATTCCCAACAAATGCACGGCCAGTCAGTATGTGAAACCAATTAAGAACTCAAACACTGATTTTTCACGAGTATTACCATCCAGAAGTAGAAATGTTTATAGCTGTGATTTATGTAGTTTGCGATTTTCTAATGGTTTAAAATTGCAAGTTCATGCATTACAACATAGAAAACAAACACACTACTTAAATTCATTGAAAGGGAAGTTACCTCAAACAGCCTCAAAGATAAATGTAAAACAACGTTTTAGGAAAGGTTTACAAGAACATTCTGGTCAATGTGCAGAAGATAAATTGTATCAGTGTAATGAACGACCTGAAGCATTTTATGCTAGGCTTGGTATCAAAACACATTTGAATGAACATACAGGAACCAGACCTTATAAGTGTGAAAAGTGTGGGAATGCTTTCTACAATAAATGGTCTTTGGCTAGACATAAAAAATTACATAAACTTGAATACGTGTGTAGTCTTTGTGGAATCTCCTTTAGCTTCAGTGAACAGTTAGAAAATCATAAGTGCTCTTTTACAAAGCCTGTTACTATGATTGATGAAGCTTCTGAATACTTACTTCAACCTCTTGATTCATTCAATATCAATAGTTCCAAACATAATGAAAGACACCTGGAAGTAAATATAAAGAGTTCTACAGCTAAAACCATATGTAAGAAGAATTCTTGTAAAATTTGTGGGAAGACTATGGCTTCTAGGATTACTTTGAAAAAGCATATGTATTTACATATTGGAAAAACTAAACAATGTACTTTCTGTGATAAAAAATGCTCTTCTTCATCCCGTTTAAAAGATCACATACGTGCTTGTCACACATTTGAAAAACCATACAAGTGTGACTTATGTGATAAAGCATATGCTTCATCTAACACGCTCAGAATACACAAACAAAAGAAACATGGTAATAAAAAAAACATGATAAAAGAAATATCTACTGAACAACATTCAGCCACACAAGAAAATTTGGTCAAACAACAAAAAATGAGAAGTCATCTTATTAGAAAAGCATTCAAATGCAGTAAGTGCCCTGCCTTGTTAACTACTTATGGCAACTTAAAAAGGCACCTAATACGTTTTCATTTGAAAGGGAAAAAGGAAGAATCAGTAAACATTTATAAATGTGAACACTGCGAAGCATCATTTCATATCAATTCCTCCTTGAACAGACATATAAACCAATTTCATTCAAGAAAGGTTAAAGATATGTCAGCATTTAAATTTGTTTCCCCCACTAGTAATGAAAAGGATGTGTCAGAAGTAACTATAACTAGTTCTATAGCAGGAAATCCTGGTAATCATATCCTAGATTCAGAAAAACCATTTCAATGTAATTTGTGTGATAAATCCTTTTCTCTCTCAAGCCGTTTAAAAGATCATTTACATTGTCACACACTTGAAAAACCTTATCAGTGTCATTTATGTGATAAGGCATATTGTAGTTCTGATGCCCTCAGAGCTCATAGAAATCACAAGCACAAGTTAAAGGGAAAGGGAATAGGAAAGCTAGTGCACCAATGTGATGAATGCCAAACACAGTTCTCAACTTCAGGTTATTTATTGAGGCACAAAAACCGTTTTCATTTGAAAAATACGCAAACAGAGGCAATAGAAGAATACAAATTTGAGCAGAGAGCAGCATCAATTCAATTAATTGAATCTGTTCACCAGCACAATGATCTCAAGTCAGGAAACATTGAAGGCAGTTTTGCATCAAAATCTTATCCAGAAACAAAATCTATTGAGTGTAATTACTGTACAGCATCATATAACTATTGTAAGAGCTTTGTCAAACATCTTTTTCAGAATCATGGGATAAAGGAAGTAGAAACACCAAAGCTGGAATTTGAGGTTGAATGTGATGTGTGTCATAGGTTTCTTCGGAAGGGTAATCTCAAAAGACACAAACGTGATGTTCATAATATAGAGGAATTAGAACAAGATACATCGGAAAATATACTTCCAGATAATATACTCAGGCATGTTCGTCAAAAAAAAACTATCAGTAGCGCATATGCCTTAAATTCTCAATCTAATCATCAATTTAATAAATGTGACACAGTATTTAATCAGAATAAATCTCTTGTAAAGCCCAAAGCTAGTGTTCATGTGGAAAATAAAAAGAAAACATTTGATATTAATCCCAGTAGAAAGTGTGGAAAATCTTTTAAACAGCTTCAAAACATGGAAGAGCATATGCTCACACATTGTAATCCAACTTCTTTATTTCACTGTGACATTTGTTCTTTATCTTTTCAGACATTGAATGATTTAAAGAATCATAAGCAAAGTCACAAATGTAAATCATCCTTAAGAATCGTAGAATCAAAAAGTAAAGAACTAGTTTCAAAAAAGCACAAATGTGATATATGTAATAAGTTGTTTTCAAGAAAGGATGCAGTGAATCGGCATAAGAAGATCCATGAAAATGTATTCCCTTATAAATGTGAAATATGTGAAAAACAGTATTAA
- Protein Sequence
- MNVHELCFVSAKEMDVSNCESEEEELPRPETVTVIQDEFAEDTDPFVSHNSDPLSVDPLSLERSIEPPRQPIKEEQGDISEVCVKIELSDTEDEISNVSICHMPEDDGYRSGNDEDVLHKNQPKSNRINNAQTNINESVANKLNEKLGEVENANVKKGASAQEGNSKTRRSQGNGVSEIQANVCSNIDLCYPEVGSGILDRSCGSEVEVSQNQQKRTTKENNVNGPKETTCLERDNSNTLGSPFAETRQALAGNSFKTSVNFSKHKEPKERIEETEKLLPLCNIERKLKVVLTRCKEAEMLASSMKLAGQRLSERKHNNDVPAINLSPTRGNEINSVKGSRVHEMPEKKISILKIGRNRDANGWRVMSAGEKVSSKLRTKSAKVQKTVASQDLENALVPGDESASSVSRDKTISGKEVQDFSERRDELGEHQTADGTGGSVRKFLLENSSEGAVLKPWSCIICHKSFDNPFAMSGHTGHCKRRLKNERICRTLTDLKEHLQVVDRYKCEICQQKFASVKGMKLHKSRVGHNHDLKENEKHLNLNTPVAQLQDLQKFEEKLRNNPHTPIPNKCTASQYVKPIKNSNTDFSRVLPSRSRNVYSCDLCSLRFSNGLKLQVHALQHRKQTHYLNSLKGKLPQTASKINVKQRFRKGLQEHSGQCAEDKLYQCNERPEAFYARLGIKTHLNEHTGTRPYKCEKCGNAFYNKWSLARHKKLHKLEYVCSLCGISFSFSEQLENHKCSFTKPVTMIDEASEYLLQPLDSFNINSSKHNERHLEVNIKSSTAKTICKKNSCKICGKTMASRITLKKHMYLHIGKTKQCTFCDKKCSSSSRLKDHIRACHTFEKPYKCDLCDKAYASSNTLRIHKQKKHGNKKNMIKEISTEQHSATQENLVKQQKMRSHLIRKAFKCSKCPALLTTYGNLKRHLIRFHLKGKKEESVNIYKCEHCEASFHINSSLNRHINQFHSRKVKDMSAFKFVSPTSNEKDVSEVTITSSIAGNPGNHILDSEKPFQCNLCDKSFSLSSRLKDHLHCHTLEKPYQCHLCDKAYCSSDALRAHRNHKHKLKGKGIGKLVHQCDECQTQFSTSGYLLRHKNRFHLKNTQTEAIEEYKFEQRAASIQLIESVHQHNDLKSGNIEGSFASKSYPETKSIECNYCTASYNYCKSFVKHLFQNHGIKEVETPKLEFEVECDVCHRFLRKGNLKRHKRDVHNIEELEQDTSENILPDNILRHVRQKKTISSAYALNSQSNHQFNKCDTVFNQNKSLVKPKASVHVENKKKTFDINPSRKCGKSFKQLQNMEEHMLTHCNPTSLFHCDICSLSFQTLNDLKNHKQSHKCKSSLRIVESKSKELVSKKHKCDICNKLFSRKDAVNRHKKIHENVFPYKCEICEKQY
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -