Basic Information

Gene Symbol
Kr
Assembly
GCA_018342105.1
Location
JAFIRS010000059.1:529315-543692[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.0023 0.27 12.8 1.9 1 19 205 223 205 227 0.91
2 7 6.4e-06 0.00074 20.9 6.1 1 23 230 252 230 252 0.98
3 7 9.1 1e+03 1.5 0.1 5 19 262 275 261 278 0.83
4 7 5.1e-06 0.00059 21.2 0.8 3 23 287 307 285 307 0.98
5 7 0.0001 0.012 17.1 2.4 1 23 313 336 313 336 0.96
6 7 6.9e-06 0.00079 20.8 1.2 1 23 342 364 342 364 0.99
7 7 1e-05 0.0012 20.3 0.3 1 23 370 392 370 392 0.95

Sequence Information

Coding Sequence
ATGAATCCTGCTGGTACTGTTTTAACTTCGGAATTCTCAATGGTTTGTCGAATTTGTTTTGGAAGACAGGATTTGAAACTTTTTGAAGAATATCAGGGTTTATTGAATCTTTTCAGGAATATTGTCAATATTGAGATTGAACATGACTCTCTTCCGAAAAATATATGCAGCAAGTGCCTTGGTAGACTCGAAGGTATTTCAGGATTCATAACTTCTGCAAAATATACTGATAATCTTCTTAGAACCCTTCTAATCAAGGAGATCGAAGAACCTGTTGCGAAATCAGAAGAAACAAATTCATGCGAAAAATATAGTAGAAATGAGACTGGGGCAAAATATCCGTTAACTATCAGTCCTAATGCAAAAATACAAGACACAGAACACCCTATAATTAAGCAAgaacttgaagatatatttaaAGAAAATCCCAATCTactgaatataaaaaatgaaagcaTAGAAATTGAAAAAGAGGAAAATTCCAATATATCGAATATAAAGATTGAACAATTATCGAATGATGGAGAATTTTGTGAAATGAGAGATGAAATATATTGCCATTGCGAAGCTTCTGGTCTATCATCTACAAATGGTGAAGACTCATGTAAACCATTTTTCTGTAGGATATGTTCCAAGAGCTTTTCACAAGAAACTGACTTATTCGAACATTTTTGGACACATGAGACTCATACATGTGAAAAATGTCTTAAAACGTTTACCCATAGAAGCTCCTTGGCGAAACACATGAGGTTGCATTTTAGTTACAAACCTCATCAGGGTAAAATATGCTCAACATTTTTCTCAAAGAACAACGTGAGAAAGCATAAAGTTGTTCGATTTAATCGAATGCCCTTTGGTTGTAATGATTGTTCCAAGTTTTTCGCTAAAAACAGTGATCTGATTATACACCAGAGAAGGCATAATGGAGAAAAACCTTTTGAATGTCCAGTCTGCCACAGAGGGTTCACTCTATTACACAATCTTACATCTCATAAACAAGTCCTTCACACTAGGAAGAGGAcattccaatgcaaaatttgtggCAAACTATTTTCCCTTAAAAAGACCTTGGCTGTCCACTTGAAAAAGCATTCTGGCAAGCGACCTTTTCAGTGTCCTTCTTGTCCTAAGAGTTTTACTGTTGAAAGCAGTTTGACTAGTCATTTGGGGCAGCATGAATCCAAGCAAGAAAACAAGAAATTACTGAAAAGTTCCATTTGTTCTGACCTCGGAAGGGATGACCTGTTGATCCATATAAATATCCATTCAGAGCGAAATAAGCAACATCCGAAACAACAGAAGGATAATGAGCAAGAGGAGATCGCCAAAATGTCAAAGAATAATAACTGTATCAAGCTAACTGATAGTGATCTTGAATTTGACATCCTGGAAGAAAAATAA
Protein Sequence
MNPAGTVLTSEFSMVCRICFGRQDLKLFEEYQGLLNLFRNIVNIEIEHDSLPKNICSKCLGRLEGISGFITSAKYTDNLLRTLLIKEIEEPVAKSEETNSCEKYSRNETGAKYPLTISPNAKIQDTEHPIIKQELEDIFKENPNLLNIKNESIEIEKEENSNISNIKIEQLSNDGEFCEMRDEIYCHCEASGLSSTNGEDSCKPFFCRICSKSFSQETDLFEHFWTHETHTCEKCLKTFTHRSSLAKHMRLHFSYKPHQGKICSTFFSKNNVRKHKVVRFNRMPFGCNDCSKFFAKNSDLIIHQRRHNGEKPFECPVCHRGFTLLHNLTSHKQVLHTRKRTFQCKICGKLFSLKKTLAVHLKKHSGKRPFQCPSCPKSFTVESSLTSHLGQHESKQENKKLLKSSICSDLGRDDLLIHINIHSERNKQHPKQQKDNEQEEIAKMSKNNNCIKLTDSDLEFDILEEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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