Basic Information

Insect: Glyphodes pyloalis
Gene Symbol: ZFX
Assembly: GCA_037074685.1
Location: JAYKKO010000053.1:515161-526020[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 33 0.0019 0.18 13.3 0.4 2 21 176 195 175 196 0.93

2 33 0.53 51 5.5 0.2 3 23 204 224 203 224 0.95

3 33 0.019 1.8 10.1 0.4 1 23 229 252 229 252 0.96

4 33 0.0025 0.24 12.9 0.7 2 23 258 279 257 279 0.94

5 33 0.01 0.97 10.9 1.2 2 22 283 303 282 303 0.91

6 33 0.0034 0.33 12.4 0.9 2 23 347 369 346 369 0.95

7 33 0.45 43 5.8 0.8 2 23 376 396 375 396 0.93

8 33 0.032 3.1 9.4 2.2 1 23 403 425 403 425 0.98

9 33 0.0083 0.79 11.2 4.2 1 23 431 454 431 454 0.94

10 33 0.015 1.4 10.4 0.3 1 23 462 485 462 485 0.95

11 33 0.0033 0.32 12.5 6.9 1 23 495 517 495 517 0.98

12 33 0.0019 0.18 13.2 0.3 2 21 627 646 627 647 0.91

13 33 0.0015 0.15 13.5 2.3 1 23 705 728 705 728 0.95

14 33 2.3e-06 0.00022 22.4 1.0 1 23 762 785 762 785 0.96

15 33 8.6e-05 0.0083 17.5 3.0 1 23 791 813 791 813 0.93

16 33 0.00012 0.012 17.0 1.5 1 23 820 842 820 842 0.98

17 33 0.014 1.3 10.5 0.1 2 21 968 987 967 988 0.94

18 33 0.2 19 6.9 0.2 1 23 1019 1042 1019 1042 0.93

19 33 0.16 16 7.2 0.2 1 21 1047 1067 1047 1069 0.89

20 33 0.25 24 6.6 8.6 1 21 1072 1092 1072 1093 0.93

21 33 0.00054 0.052 15.0 1.0 1 23 1110 1133 1110 1133 0.95

22 33 0.0014 0.13 13.7 3.0 1 23 1139 1161 1139 1161 0.97

23 33 2.2 2.2e+02 3.6 0.5 1 23 1195 1218 1195 1218 0.87

24 33 7.5e-05 0.0073 17.6 2.5 2 20 1346 1364 1345 1366 0.93

25 33 0.14 14 7.3 0.0 3 23 1373 1394 1372 1394 0.96

26 33 0.029 2.8 9.5 0.1 2 23 1400 1422 1399 1422 0.95

27 33 0.00013 0.012 16.9 0.1 2 23 1428 1449 1427 1449 0.96

28 33 1 97 4.7 2.4 2 21 1453 1472 1453 1473 0.91

29 33 0.00051 0.049 15.0 0.3 1 23 1499 1522 1499 1522 0.95

30 33 0.00074 0.071 14.5 0.5 1 23 1528 1550 1528 1550 0.95

31 33 0.061 5.9 8.5 0.2 1 23 1556 1578 1556 1578 0.98

32 33 0.26 25 6.5 0.8 1 23 1584 1607 1584 1607 0.82

33 33 0.033 3.2 9.3 0.8 3 23 1615 1636 1613 1636 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	33	0.0019	0.18	13.3	0.4	2	21	176	195	175	196	0.93
2	33	0.53	51	5.5	0.2	3	23	204	224	203	224	0.95
3	33	0.019	1.8	10.1	0.4	1	23	229	252	229	252	0.96
4	33	0.0025	0.24	12.9	0.7	2	23	258	279	257	279	0.94
5	33	0.01	0.97	10.9	1.2	2	22	283	303	282	303	0.91
6	33	0.0034	0.33	12.4	0.9	2	23	347	369	346	369	0.95
7	33	0.45	43	5.8	0.8	2	23	376	396	375	396	0.93
8	33	0.032	3.1	9.4	2.2	1	23	403	425	403	425	0.98
9	33	0.0083	0.79	11.2	4.2	1	23	431	454	431	454	0.94
10	33	0.015	1.4	10.4	0.3	1	23	462	485	462	485	0.95
11	33	0.0033	0.32	12.5	6.9	1	23	495	517	495	517	0.98
12	33	0.0019	0.18	13.2	0.3	2	21	627	646	627	647	0.91
13	33	0.0015	0.15	13.5	2.3	1	23	705	728	705	728	0.95
14	33	2.3e-06	0.00022	22.4	1.0	1	23	762	785	762	785	0.96
15	33	8.6e-05	0.0083	17.5	3.0	1	23	791	813	791	813	0.93
16	33	0.00012	0.012	17.0	1.5	1	23	820	842	820	842	0.98
17	33	0.014	1.3	10.5	0.1	2	21	968	987	967	988	0.94
18	33	0.2	19	6.9	0.2	1	23	1019	1042	1019	1042	0.93
19	33	0.16	16	7.2	0.2	1	21	1047	1067	1047	1069	0.89
20	33	0.25	24	6.6	8.6	1	21	1072	1092	1072	1093	0.93
21	33	0.00054	0.052	15.0	1.0	1	23	1110	1133	1110	1133	0.95
22	33	0.0014	0.13	13.7	3.0	1	23	1139	1161	1139	1161	0.97
23	33	2.2	2.2e+02	3.6	0.5	1	23	1195	1218	1195	1218	0.87
24	33	7.5e-05	0.0073	17.6	2.5	2	20	1346	1364	1345	1366	0.93
25	33	0.14	14	7.3	0.0	3	23	1373	1394	1372	1394	0.96
26	33	0.029	2.8	9.5	0.1	2	23	1400	1422	1399	1422	0.95
27	33	0.00013	0.012	16.9	0.1	2	23	1428	1449	1427	1449	0.96
28	33	1	97	4.7	2.4	2	21	1453	1472	1453	1473	0.91
29	33	0.00051	0.049	15.0	0.3	1	23	1499	1522	1499	1522	0.95
30	33	0.00074	0.071	14.5	0.5	1	23	1528	1550	1528	1550	0.95
31	33	0.061	5.9	8.5	0.2	1	23	1556	1578	1556	1578	0.98
32	33	0.26	25	6.5	0.8	1	23	1584	1607	1584	1607	0.82
33	33	0.033	3.2	9.3	0.8	3	23	1615	1636	1613	1636	0.95

Sequence Information

Coding Sequence: ATGAGCAAAGAAATAGACGTAAAGGCTCTCGTATCACACCTGGTGCGGGGAGACGGTGTCGATAAGTGCCGAATATGCATGGGCGATACTTCAGAAGGGCAGGTGTACCTCGGCGATACCGTAATGATGGATGGCGAGAGGCCTGTGACCTTAGCCGAGTTGCTAGAAGTCATCACAGGAGTGGAGGTGCCGGACGCTCCTGACTTGCCAAGCGGACTGTGCTCGTTATGCTCTGGCTCGGCTATTGATGCTGCTAACTTCTCCATACTTTGTCGGAAATCTGACAACAAATGGAAAACAACGCTACAGCTATTGGAGAACCTACCGATGGATGTTAAAGAACAGAGCAAATCATTGTACGTTCTACTTCAAGGTGATCAGATCACTACTGATATTAAATCTGAAAGTCCGGATCAAACAAAACAAGAGCAAGTGTCTCGTACTAAGACCCCATCTCTGTCAGCAGAAAAATTACAAGTTTCAAAACCAAAGAGGAGTCGTAAAAGATATAGGAAGTTGGAGTGTCAATGCCCTGCCTGCGGCAAAGAGTTTAAAAATGCGGAAAAATTGTCATTGCATTTGAAAGAGTCGTCGGATTACAACAGAGCTTGTCATATCTGTGCTCTAGTTTTGAGTAGGGATGACCTGATCAAGCATTTGAAGGtcatacacaaaataaaaccgTATGCATGTAAAAAATGTCCCGCATTATTCTCCAACGGTTCAAAGTTACTTACACACTTGAAGCTAAGTCATGCTAAAGGAATGTGTACTTGTGGTGAATGCGGTCGCAGCTTTCAATCTGAGAACGGTTTTAATGCTCACCAAGCCTTGCACCTGCACAAAACTTGTCCCGGCTGCGACAAAGTGTTCAGAAACAGACTTTGCTATATGTACCACGTGCAGACGTGTTgcgatttgaataaaaacagaCAAGATGCCTACAgaacaaaacacaaaatgtttatagaagttaacaataaaatcagTAAAAGAAAAGTCAAAGTAGGAATGAGAGGCAGTTCGTTCGATGAATGTATCTGTGATTATTGCAACAAAAGGTTCTCCGGGAAGAAGTTTGTTGCGGCACACATTCAAATTGTTCACACGAAGACTACTCACACTCCGTGCCCACACTGTGGGAAGTTGTACGCTGCGGCCCATATGGGAACACATATAAAGACACACGAACAAAAGATGGTAGAGTTTACGTGTAAACATTGTAATCTTGTTCTCAAGAGCAGGCTGGGTTATATCCAGCATTTACGCCTACACACTGGCGAGAAACCATACGAATGTAAGCATTGCGGGGAGACGTTCTCGGCTTCTTCACGGAGGTCACATCACATACAGAAGATGCACAGTACGGAGGATGTACTCAAACATGCCTGCTCGTTGTGCCCAGCCCGTTTCGCTTTGCCTTTCCGGCTTAGGAAGCATATGGCAACGGTGCATGGGGAAGGAGCAGAGAAGAGTCCACAGTTTGAGTGTCCGGAGTGTCACGAGAAGTTCAGTAGTTGCCGGGGACTGATGCACCACAGCCGGAAGCATCAGAAGGGGATTATTAGAAAGCCAATGAAACGAGTTGTAGTAGACATCACGACGCCCCTGCCCTCAAACACGTGCCAATCCTGCTGTGTGAGCGCCATAGCCGCCGTCAGGTTTTCGCGCCTCTGCCAAGCTTCCGACAAAAAATGGCATGAGATCTCTAATTACTTGGCAAATATGAACATCCCTGCCGAAAGAACAGCGTTCCTTATTGTTGGCGACGAGAAAATCACCACTATATCCGATTCGAAGAgctatacaaataaaaagcaagCACTGAAAGCGGTTAACAGACCCAAAACTAACGGAAAGAAGATAAAATGCGATGCCCAATGTCCGGAATGCGGAAAGAGTTTCACAAACGTGGGCTCGTTTAATTTTCACATGAAGGACTTTAAAAAGATAATGTGTTTTAAATGCAAGAAAATATTACCGCTGAAATCGTATGTGCTTCATGTTAAAAAGCACGGTGTAGCCAGTTACTTGTGCAAGTATTGCGCGCACGTTTTTCAGTGTAAAGGCACTTTTTTGCGTCACAggaatttgtgtaaatatagaGGAAGCCACGTGTGTGCGGAATGTAAGAAGTGTTTCCCGTCTGAATTTAATTTGGTGTCGCATTTAGCAAGCAAGCATTGTCCAAAGGTTTGCGCTGCTTGCGGTAGGAAATTCAACCTGCTTTGCTTCAAGCATCATTTGAAGAAGTGCGCGAATTCAAAACCGATGGAGAATGTTTATATATGCGACTACTGTGGCAAGGAATATAATCAGAAGAGCGCTTTGAAGTTGCATATGCGCTTTACGCACGTGGTTGGCTGGGAGTATCAGTGCGAACAGTGCGGGAAGAAGTTTTCGAACCCTGCTCACTTGCATGAACATGATAATACTCATAACAGAGTTTATGATCGCTACGTATGCAGTATTTGTGGCTTGAAATATAGCACGAGGAGAGGATATGAAAGGCATTATAAGCGTCACTTTGGTGCTGACGGCGCTTTAACTGACGTGGAGGAAGACTGCGTCCTGCCCGGGGGACTCTGCCGGGACTGCGCTGAAAGCGCCTTGGCAGCTATAAACTTCAGGCAGGCTTGCAAGCAGGCGCTCCACCAGTGGACTGATGCCACCGCCTTTTTGTCCACCTTGATACACCCCCAGCAGAAGGACAAGGCATTTTACATATTCTACAATATGGAAGACAGAACTATTATAGGTGACCAGACAGTTAGGGCAAGCGATAAGAGGCGCGCGCTGAAACGCCTTAATTCCAGATTCGCTGATGAAACGCAGGAAGAGGAAGTGGCGAAGGAAATATTAGAAGTGAAGAAACTGAAAAGAGCAGAGAAGAGTACTTGGGTTTGCCCGGATTGCGAGAAGAAGTTTCTGTCTCCGCAAGAACTGAATTCGCATTTGAAGAATACGTTGAAACGGGCTTGCGAAGAATGCGGGGTAGTTATGGGCAAGGCTAAGCTGGCGCTGCACTTGAGCGAAGTGCACGGTAGGTTGGTGTTCTCTTGCGGTGTCTGCCAATCTGTCTTCGAAGAACCTAATTCTTTAGAGACCCACTTTGATAAATCACACGGAGATGACTCTCATCAGTGCAAAGTCTGCGGCAGCGGTTTCGCAAACGAGAGAGCGTTGGGCGCGCACAATTACGCCCATTCTTTATTCCTCTGCAATAACTGCGGTAGATGTTTCGAGAACAAGAAATGCTACTTCCACCACCAGAAGCAGTGTAAGCGTTCAGCTAAATCAGCTAAGAGCGGCCCGGAGATGTCTGAATACATCTGCGATCATTGTGGGAATTCTTATACGAAGAAGCCGTCGCTACGCGTCCATATAATACAGAAGCACTTGAATGTTTTGCCTCACGTGTGTACTACTTGTGGGAAGCGGACTTCTACAATAGCGCATCTAAGATCGCACGAGAAAGTGCATTTATTGGAAAGGAAGACTTTCCAATGCTACTGCGGTGCCAAGATGAGGACTGCGTTGGGTTACCAGCTTCACATGCGAATACATTCTGGTGAAAAGCCTTATCAGTGTGAGGAGTGCGGTGATAAGTTCCTGTCGGCTTCTCGACGTTTGGACCACATTAAGCGAAGGCATAGGAGTGCCAAAGAAATGCCACACGGTTGTACTGAGTGTCCGGCTAGGTTCATCGAAGAGGAATCATACATACCGGCAGGCGCGTGTGCCCCCTGTGCGGCCGCAGCGCTCGCCGCTCAAGAATTCCGCATACTAACCCAAAAATCCCAAAAAATATGGCTGAAAGCGATCACCAATCTCGCCGACATCCCATCCTCTTACGCAGAGGACGTTAAATCCCTTTGCGCCTTCGTTAAACCAGAAAATATGACCATGCATGTAGTTAAAGACTTTACAGGCGGTGATAGTAAAACAGTCTTGAGTCGGCTGAAGAATCGGCTCACCAAAAAGAAAGCTAGTCCAGATAAGAAAACAAGGGTAACCCGTGCAGGGCCTACCTGCGAGTGCCCTGACTGCGGTAAGTCTTTCTACAGCCCTTACTACCTGTGCCAGCATCTGAGCAACAGCGGGCAGAAGGAAGCCTGCCCCATTTGCGGTATCGTACTTATCAGAGGAACTGAGATGAAGCAACATTTATCTAAAGTTCATGGTGAGAAGGTCGTCTCTTGCGCGCAATGCCCTCTCCTGTTTACAAGTGAGCCGCAGCTGGAGAAACACGTTAAGAAGTCACACAGGCCTGGGTCATTGACGTGTTCAGACTGTGGGCGGACGTTCCCTAGGCTCGCCACTTTCGAGGCGCACGGGCAAATGCATGCAGTGAGGACTTGCAGGGCCTGTGGTCGACAGTTCACGAACCGCGTCTGCTACAGGGAGCACAGGTCGAAGTGTGAGCCGGATGCGCGGCCTGCTACACGCTCTTTGCCGAGAAATAAGCGTTCGAACATCCGCGACCCTGCGACTTTCACTTGCGATTACTGCGGGAAGACGTACCTATCTAGGCCTCAATTAAAGAATCACATAATCTGGATACATATGGATGTGCGTCCTCACCAGTGTCAGTGGTGTGGGAAGAGGTTCTACACGCCGGCGCGGCTGGCTGAGCACACAGTTGTTCACACAAGGGTGAGGAACTTCGAATGCGATATTTGCGGAGCGAAATTGGTGACTCGGATGGCGATGGTCTACCACAAGAGGCGCCATACTGGTGAGAAGCCTTACACGTGTGAGGATTGTGGAGAAAAGTTCCTATCGTCTTCGCGGAGGTCGGAACACGCTAAGAGGAGGCACGGGAAGGGTCCGCTGGTGCACTGTCAGGAGTGTCCAGCTATATTCCCGAGAGGTATAGAGCTGAAGCGACATATAGAGAAGTGTCATAGGAAAACGGAGCCGGCGCCTGAGTTTATGGTAACTGAGAGCACGTATCCTCCTGCGAAGAAATTTAAGACAGATGACATGGTGGTAGAAAACAAGTTTGATGTTAATGAGATGAAGCCGTATTTAGAAATTGATTGGAAAACAGGTGACGAGGGTGCGGTGGTCAGGCCCCTGTGA
Protein Sequence: MSKEIDVKALVSHLVRGDGVDKCRICMGDTSEGQVYLGDTVMMDGERPVTLAELLEVITGVEVPDAPDLPSGLCSLCSGSAIDAANFSILCRKSDNKWKTTLQLLENLPMDVKEQSKSLYVLLQGDQITTDIKSESPDQTKQEQVSRTKTPSLSAEKLQVSKPKRSRKRYRKLECQCPACGKEFKNAEKLSLHLKESSDYNRACHICALVLSRDDLIKHLKVIHKIKPYACKKCPALFSNGSKLLTHLKLSHAKGMCTCGECGRSFQSENGFNAHQALHLHKTCPGCDKVFRNRLCYMYHVQTCCDLNKNRQDAYRTKHKMFIEVNNKISKRKVKVGMRGSSFDECICDYCNKRFSGKKFVAAHIQIVHTKTTHTPCPHCGKLYAAAHMGTHIKTHEQKMVEFTCKHCNLVLKSRLGYIQHLRLHTGEKPYECKHCGETFSASSRRSHHIQKMHSTEDVLKHACSLCPARFALPFRLRKHMATVHGEGAEKSPQFECPECHEKFSSCRGLMHHSRKHQKGIIRKPMKRVVVDITTPLPSNTCQSCCVSAIAAVRFSRLCQASDKKWHEISNYLANMNIPAERTAFLIVGDEKITTISDSKSYTNKKQALKAVNRPKTNGKKIKCDAQCPECGKSFTNVGSFNFHMKDFKKIMCFKCKKILPLKSYVLHVKKHGVASYLCKYCAHVFQCKGTFLRHRNLCKYRGSHVCAECKKCFPSEFNLVSHLASKHCPKVCAACGRKFNLLCFKHHLKKCANSKPMENVYICDYCGKEYNQKSALKLHMRFTHVVGWEYQCEQCGKKFSNPAHLHEHDNTHNRVYDRYVCSICGLKYSTRRGYERHYKRHFGADGALTDVEEDCVLPGGLCRDCAESALAAINFRQACKQALHQWTDATAFLSTLIHPQQKDKAFYIFYNMEDRTIIGDQTVRASDKRRALKRLNSRFADETQEEEVAKEILEVKKLKRAEKSTWVCPDCEKKFLSPQELNSHLKNTLKRACEECGVVMGKAKLALHLSEVHGRLVFSCGVCQSVFEEPNSLETHFDKSHGDDSHQCKVCGSGFANERALGAHNYAHSLFLCNNCGRCFENKKCYFHHQKQCKRSAKSAKSGPEMSEYICDHCGNSYTKKPSLRVHIIQKHLNVLPHVCTTCGKRTSTIAHLRSHEKVHLLERKTFQCYCGAKMRTALGYQLHMRIHSGEKPYQCEECGDKFLSASRRLDHIKRRHRSAKEMPHGCTECPARFIEEESYIPAGACAPCAAAALAAQEFRILTQKSQKIWLKAITNLADIPSSYAEDVKSLCAFVKPENMTMHVVKDFTGGDSKTVLSRLKNRLTKKKASPDKKTRVTRAGPTCECPDCGKSFYSPYYLCQHLSNSGQKEACPICGIVLIRGTEMKQHLSKVHGEKVVSCAQCPLLFTSEPQLEKHVKKSHRPGSLTCSDCGRTFPRLATFEAHGQMHAVRTCRACGRQFTNRVCYREHRSKCEPDARPATRSLPRNKRSNIRDPATFTCDYCGKTYLSRPQLKNHIIWIHMDVRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICGAKLVTRMAMVYHKRRHTGEKPYTCEDCGEKFLSSSRRSEHAKRRHGKGPLVHCQECPAIFPRGIELKRHIEKCHRKTEPAPEFMVTESTYPPAKKFKTDDMVVENKFDVNEMKPYLEIDWKTGDEGAVVRPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -