Basic Information

Gene Symbol
grau
Assembly
GCA_000818775.1
Location
Scaffold113:196595-207192[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 4.4 3.5e+02 2.1 1.8 2 23 253 275 252 275 0.92
2 14 0.0072 0.57 10.9 1.3 6 23 284 301 284 301 0.99
3 14 0.0026 0.21 12.3 1.2 2 23 308 330 307 330 0.94
4 14 0.001 0.081 13.5 0.7 1 23 338 361 338 361 0.95
5 14 0.0052 0.41 11.3 0.6 2 23 382 404 381 404 0.94
6 14 0.054 4.3 8.1 0.1 6 23 413 430 413 430 0.98
7 14 0.0051 0.4 11.4 0.1 2 23 559 581 558 581 0.96
8 14 0.019 1.5 9.5 2.2 6 23 590 607 590 607 0.99
9 14 0.0064 0.51 11.1 0.3 2 23 614 636 613 636 0.94
10 14 0.00027 0.021 15.4 0.6 1 23 644 667 644 667 0.95
11 14 0.19 15 6.4 0.4 2 23 688 710 687 710 0.95
12 14 0.048 3.8 8.3 0.2 6 23 719 736 719 736 0.99
13 14 0.078 6.2 7.6 0.3 1 23 750 773 750 773 0.91
14 14 0.00091 0.072 13.7 0.2 2 21 779 798 779 799 0.95

Sequence Information

Coding Sequence
ATGATTTGCCGCTTATGTTTACAAGAAAGTTGTGATTTTAAAAGTGCGTTTGACTCGGCAGACAATGAACGGACTATCGCTTCAATTATTGAAAAGTATTTCTGGTTTGAGTTCCAGCAAAACGATCAAATATCAACAGTGATTTGTAACAATTGTTGGCTTAAAGTTTCTGACTTTCATGAATTCTATAAAAGTGTTGAAGAGGCCCAAAGTCATCTGGGCGAAAATGTCGTAGTGAAAATTGAAAATATTAGTGTGGAGCATTCCATAGAAAATGTAATAGTTCAGTCGATCCCTTTTTCTAGCAAGCAAGAGCCCAACGATTTTGCAGAAGCCAATGATGAGGACCCTTTTGATATGCCAATAGACAGAGTAGATAATAATCCGTCATCATTACTAAAAAGAAAAGATTCCAATGATAAATTAAGGACACAAACTTATGGTATTAATTCTATGGAAACGGTTGAGAATGTCGGTGATGACAAAGACGAAAAATCTAGTGGTCATAACGGCAGAAAAGCAGCAGTTAAGAAGTCTTTGAAAAAGAAAAAGCCTATTAAATCTGCCACAACGGGTAGAACTaaaaaaaaTCCTATGCCTAAATTACAACGGAATGTAAACTTATGCTTAACgaaaaatacaagaaagttgggcaaaactgaaaacaacaactcaaaaaaagaaaaagtcaaaaaacCGATTGAAGATCCGAAAAGTATAGCTTTCGATGAAGAGATAGCTAACTTTATGTCGTTACATTGTGATCGGTGCAAATTAGAGGCCAAGAATTTTAATGCTCTGCACAGTCATATGCTCGCAGAGCATAACGTTAAAGGTTACGCAAGATGTTGCAATAGGAGATTTTCTTCACGCTTTTTATTACTTGATCATATACGCCGACATTCTAATCCTGACAGTCTGAAATGCGAGCCATGTAATCGTATTTTTGCCGATCGCAATTCTCTGCGCCACCATTTACAAATCAAACATCAAAAAGATGAAGATAAAATGTTTTCCTGCTCTCGATGTCCAAAAAAGTTTGTTAAAATGTATTTGTTGCGACAACATGAGCTTGTCGGCCATAGCGATCATAAAAACGCTTGTCTGGCTGTTGATGAAGAGATAGCCAAGTTTATGTCGCTGCATTGTGAACAATGCAATGAAGAGGCGACCAACTTTACAGCCCTTAATCGGCATATGCGTGCTGAACATAACGTGCGAGGCTACGTCAGATGTTGTAATAGGAAATTTCGTGAGCGTGGTTTGCTTGTTGAGCACATACGCGCACATTTAAATCCTGCTTGTTACAAGCAAGTAAATCCATTTTTAAGGAAAACCACTAATGCTGCGGAAGAAGTTAGGAATGTCATTAATTACAAAGATGAAAAATTTGATGACGACGATGATGGCGACCCATTTAATAGCGAGGaaacaaaaattggcaacaaaagagagagtactaaactatcaaaaaaggaaaaaTCTGTCAAGTCTGCAAGAACGATTAGAATGAAACATTCTTCGCCCAAATTACCACGGAGTGcaaatgaaaaaggtacaagaaaattgagaaaaaacgaaaacaatgattcaagaaagacaaaagtgaaaaaaccccttgaagatcccaaaagTTTGGCTATCGATGAGGAGATCGCTAAGTTTATGAAACTACAATGTGAGCGATGCAAGTTGGAAGTTGCAAACTTTAGCGCTCTTCAAAGTCATATGCTCACCGAACATAAAATCAAAGGTTACGCCCGATGTTGTCATAGGAGATTTTCGTCGCGATTTTTGCTAATTGACCATATACGACAGCATTCAAATCCTGACAGTCTGAAATGCGAACCATGTAATCGTGTTTTTGCCGATCGCAATTCTATGCGCAATCATTTGCTAATCAAACATCAAAAAGACGAAGATAAAATGTTTTCTTGTTCTCGATGTCCAAAGAAGTTTGTTAGAATGTATTTGCTGCGGCAACATGAGCTAGTGGGCCATAGCGATCACAAAAATGCTTGTCTGGCTGTTGACGAAGAGATAGCCAAGTTTATGCCGTTGCATTGCGAGTTATGTAGTGTAGAGGTGGAAAATTTCACATCTCTTAAAGGCCATATGCGTGTTGAGCATAATATGAAGGGTTATATGAGATGTTGCAATAGAAAATTTTTTGAACGTGGCTTACTTGCTGAGCATATACGCACACACCTAAACCCTGCTTGTTACAAGCAAGAGGAAGACAAACCTTTTGCTTGTTCTCAGTGTTCCAACAAATTTGTTACAGTATACTTGTTACAATTACATAAAGTGGTTGCTCATGGTGATCCCACAAATACTTGCAAAAGCTGCAGCAGAAAGTTCAACACTGCAGGTGAATTAACGGCTCATATTAAAGAGCAATGTCTGTGCGATACATGCGCGGAAGTTATATGTGGAGTTGCAGCTTTTCAACATCATATACTGGGTCATGAAAAAAGTCTTGCGGGCTCGAAAGATTCTAATGTTTGTGATATTTGCCGCCAAGATAAACTTTGTGTTCATAATACTACACGTACTTTCGATAGCAAGGTCTCCTCTTTCCATGAAAATTTTCCATTCCCTTATCAATACACATCTACATCGCAAGAAAATGCTTCCACAACGATGCTTACGCACCCGAATTATACTCACTCTTCAGGCGACCATTGA
Protein Sequence
MICRLCLQESCDFKSAFDSADNERTIASIIEKYFWFEFQQNDQISTVICNNCWLKVSDFHEFYKSVEEAQSHLGENVVVKIENISVEHSIENVIVQSIPFSSKQEPNDFAEANDEDPFDMPIDRVDNNPSSLLKRKDSNDKLRTQTYGINSMETVENVGDDKDEKSSGHNGRKAAVKKSLKKKKPIKSATTGRTKKNPMPKLQRNVNLCLTKNTRKLGKTENNNSKKEKVKKPIEDPKSIAFDEEIANFMSLHCDRCKLEAKNFNALHSHMLAEHNVKGYARCCNRRFSSRFLLLDHIRRHSNPDSLKCEPCNRIFADRNSLRHHLQIKHQKDEDKMFSCSRCPKKFVKMYLLRQHELVGHSDHKNACLAVDEEIAKFMSLHCEQCNEEATNFTALNRHMRAEHNVRGYVRCCNRKFRERGLLVEHIRAHLNPACYKQVNPFLRKTTNAAEEVRNVINYKDEKFDDDDDGDPFNSEETKIGNKRESTKLSKKEKSVKSARTIRMKHSSPKLPRSANEKGTRKLRKNENNDSRKTKVKKPLEDPKSLAIDEEIAKFMKLQCERCKLEVANFSALQSHMLTEHKIKGYARCCHRRFSSRFLLIDHIRQHSNPDSLKCEPCNRVFADRNSMRNHLLIKHQKDEDKMFSCSRCPKKFVRMYLLRQHELVGHSDHKNACLAVDEEIAKFMPLHCELCSVEVENFTSLKGHMRVEHNMKGYMRCCNRKFFERGLLAEHIRTHLNPACYKQEEDKPFACSQCSNKFVTVYLLQLHKVVAHGDPTNTCKSCSRKFNTAGELTAHIKEQCLCDTCAEVICGVAAFQHHILGHEKSLAGSKDSNVCDICRQDKLCVHNTTRTFDSKVSSFHENFPFPYQYTSTSQENASTTMLTHPNYTHSSGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-