Gpal014030.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Glossina pallidipes
Gene Symbol
CRZ1
Assembly
GCA_000688715.1
Location
Scaffold268:276544-278178[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 6.9 5.3e+02 1.5 0.9 6 22 209 225 206 225 0.92
2 8 0.86 66 4.3 0.1 2 23 232 253 231 253 0.94
3 8 0.022 1.7 9.4 0.4 1 20 261 280 261 283 0.91
4 8 0.00031 0.024 15.2 0.8 1 23 289 311 289 311 0.96
5 8 0.01 0.79 10.4 1.3 3 23 319 339 318 339 0.98
6 8 0.0013 0.099 13.2 4.5 1 23 344 368 344 368 0.98
7 8 1.3e-05 0.00097 19.5 2.1 1 23 374 396 374 396 0.97
8 8 0.015 1.2 9.8 3.2 1 23 404 427 404 427 0.97

Sequence Information

Coding Sequence
ATGTTAAAAGCTCAAGACAACGTTGTAGCACCTACTTTGCATCAACCTCTTCACTCCAAAGTAACAAATTATTTGAATGACCAGCGACGACAGGGACAATTCTGCGATTTAATTCTTGAACTAGAAAGCGGTGATTCGATTTTTGGTCATTTTTGCGTAGTAGCTGCTCAAAGTCGCTTTATTGGGGGCTCACATTTCTTACAGAAATCCCTACAGTTCTCCATACACAATCCTTTGAAAGTGACAATTAAAAATTTTAATTGTTCAGAATGCTTACAAACTATAGGTGACTTTTTCTATGAAGATGTGGTATCGATTGTAAAAGAGCATGAACCGCATTTTAAACAATTGGCTAGGATTTTAATAGTCAGTGAAATATTGAAGTTATTTCAAATACCAGAGCAATTGCAACAAATTGTGGAAATTTCAATGGAAGATTTTTGCAAAACATCAGAAACTGATTCTGCGAAACCATCAGAGGAGTCAACGAATTCAATTACAAGTAGTGATAAGAAACAAGTGCAGAATAAGCCTGATAATATATTCGAGGAGaaaaaaaCTTATTTTAAATTAAAAAATTCTCGTGCTTCTGCCGCCAACAGTAAAATCAATTATTGCATAGCCTGCGATTTCAAATGCTATCGTGTTCACGAGATGATTTCCCATATGCGCAGCTGTGAAGCATCGCATTTAACCTGCTCTTTATGTGAAGTAGGTTTCCTGGGTTGGCGTGAATACGATGCTCACCTTCGACGGCACGGAAGCGATGTGAAAAAGCCATTCTTTTGCTTGGAATGTGAAATGCGTTTTATGACACGTGCTGCCCTTACACTGCATCAACCCAAACACTCGAAAGAGACACCATATCTATGTCCGCACTGTGATAAGGGTTTTAAGTGGAAGCAGGGTCTCAATACACATTTACTGGTGCATAATAATGAAAAGCTAATGCTTTGCGACGTGTGCGGCTACAGCACCATACATATGAAAGCTTTGAAATCCCATAAACTACGTCATACTGGCGAATTCTTTAAATGTACTTATCCCGATTGTCATCATCAAACTAATCGCAAAGAAAATCTTAAATTGCATATTGAAACACATAAGCAAGAACGTCCATTTGTTTGCGAGATTTGTGGCTGTAAATTTAGCTTAAGTAAAAATTTAAAACGCCACGCCATCAAACATAATGCAGATGAAATGAAAAAATATAAATGTCAGCTGTGCTCCTTTAGCAGTCATCGATCCGATAAATTGAAGGAACATGTGCAAAGAGTGCACACGGAAAAAGCTATACAATTAGAACTACCGGAAATAGTAGAAAACGCCTTTGAAAGTAACACAGATTTAGACGAATTTAGTTTACCAAATTTAGATAATCAAGAAACAAAAGCGGATAGACGAACAACTCTTaaaaaaggcgaagataaaaataaaaaaaggacaagaaagaaaatgaattcgaaaggaaaaatggaacgtaaattaaaaaCGATTGCCCCTAAAGTTGAAACAATTCTAGGCAATGCCAATAAACTTGAGAATTTAGAAAATAAAAAAGCGTAA
Protein Sequence
MLKAQDNVVAPTLHQPLHSKVTNYLNDQRRQGQFCDLILELESGDSIFGHFCVVAAQSRFIGGSHFLQKSLQFSIHNPLKVTIKNFNCSECLQTIGDFFYEDVVSIVKEHEPHFKQLARILIVSEILKLFQIPEQLQQIVEISMEDFCKTSETDSAKPSEESTNSITSSDKKQVQNKPDNIFEEKKTYFKLKNSRASAANSKINYCIACDFKCYRVHEMISHMRSCEASHLTCSLCEVGFLGWREYDAHLRRHGSDVKKPFFCLECEMRFMTRAALTLHQPKHSKETPYLCPHCDKGFKWKQGLNTHLLVHNNEKLMLCDVCGYSTIHMKALKSHKLRHTGEFFKCTYPDCHHQTNRKENLKLHIETHKQERPFVCEICGCKFSLSKNLKRHAIKHNADEMKKYKCQLCSFSSHRSDKLKEHVQRVHTEKAIQLELPEIVENAFESNTDLDEFSLPNLDNQETKADRRTTLKKGEDKNKKRTRKKMNSKGKMERKLKTIAPKVETILGNANKLENLENKKA