Basic Information

Insect: Glossina morsitans
Gene Symbol: -
Assembly: None
Location: scf7180000651687:182988-188845[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0064 0.35 10.9 1.1 1 23 34 57 34 57 0.95

2 8 0.00056 0.031 14.2 7.5 2 23 149 170 148 170 0.96

3 8 2.5e-05 0.0013 18.5 0.1 1 23 177 199 177 199 0.99

4 8 2.3 1.2e+02 2.9 4.3 3 21 207 225 205 227 0.90

5 8 0.00014 0.0079 16.1 4.7 1 23 233 255 233 255 0.98

6 8 5.6e-06 0.0003 20.5 3.3 1 23 261 284 261 284 0.96

7 8 6.2e-05 0.0034 17.3 0.4 1 23 291 313 291 313 0.97

8 8 4.7e-07 2.6e-05 23.9 3.4 1 23 318 340 318 340 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0064	0.35	10.9	1.1	1	23	34	57	34	57	0.95
2	8	0.00056	0.031	14.2	7.5	2	23	149	170	148	170	0.96
3	8	2.5e-05	0.0013	18.5	0.1	1	23	177	199	177	199	0.99
4	8	2.3	1.2e+02	2.9	4.3	3	21	207	225	205	227	0.90
5	8	0.00014	0.0079	16.1	4.7	1	23	233	255	233	255	0.98
6	8	5.6e-06	0.0003	20.5	3.3	1	23	261	284	261	284	0.96
7	8	6.2e-05	0.0034	17.3	0.4	1	23	291	313	291	313	0.97
8	8	4.7e-07	2.6e-05	23.9	3.4	1	23	318	340	318	340	0.99

Sequence Information

Coding Sequence: ATGGAAAATTGCGTAGAAATAGAGAGCAATGTAGTGCCTTTATATAAATGTGGCGAGATTTTTTACGACATGTTGGCGGCCCAAAATATCAGCATTAGCTTTCAGTGTTCCTTTTGCCAGAAAACTTTTATAGAATTGGATATATTCTTAAAACATTTACAAAGTGATCATTATAACCCATCCACACCTACCGAAGAGTATGGGTCTGGTAACAATGAACAATTACAAGAAGAATATCGAACAGAAGAAATTTTTCTTATATCTAACGATAATGACAGTAAAATATTATTGGATAATGTAACCCATGTAACAGACACTAATTTAAAAGAAACGAATATCAGCGACGATCTCGAAGTGAATAATCTATCATGTGAGGAAGAAGAAAAATGTGTCGGGCAATCCAAACAGAAACAGCCTGTTAAAAGGCGCGCCACTCGTGAATGTATTTGTCCACATTGTCATAAAATATTCCATAAGGCTTGGTCTTTGCAACAGCATTTAAATACACACGATGGCTATGAGAAGCCATATAAATGTGAGTTTTGTCCAGCAGCATATGCCAGCAAACAAAATCTCGTAGTTCATGTCAGACGGCATAAAGGAGAGAAGCCTTTTGGCTGCCATTTTTGTGCACGTAGTTTTACTTCCACCAGTGAACGTTACATACACGAACGGTGCCATACTGGCGAGCGGCCATATGTATGCGAGTTTTGCGGCAAAAGTCATACCACTTCGTCTCATTTACTTAATCATCGTCGGCTACATTTGGACGAACGTAACTTCGTGTGCGACTTGTGCGATAAACGTTTTAACAAACGCGATGAGCTaaaaaaaCATCATAAGAATGTACACACGGAAGTGCCGCGTTCTCATGTCTGTCCGATATGCACCGCGGCTTTTAAAGGAAAAACTACATTGAAGGAACATGTAAAAATCCATGAGGAGAAAACTTACAAATGCCAAGAATGTGGCAAAACATTTGCCCAACATTCCGGTTTATATTCACACCGAAAGACTCATCAAAAGCAAAGAGACACGTTGTTAAAGGATGTAATGATGATGGCAGAAGAGACTACGACATCGTCTATTAAAATAGAAATTCTTGATGACAATGACACTATTTGA
Protein Sequence: MENCVEIESNVVPLYKCGEIFYDMLAAQNISISFQCSFCQKTFIELDIFLKHLQSDHYNPSTPTEEYGSGNNEQLQEEYRTEEIFLISNDNDSKILLDNVTHVTDTNLKETNISDDLEVNNLSCEEEEKCVGQSKQKQPVKRRATRECICPHCHKIFHKAWSLQQHLNTHDGYEKPYKCEFCPAAYASKQNLVVHVRRHKGEKPFGCHFCARSFTSTSERYIHERCHTGERPYVCEFCGKSHTTSSHLLNHRRLHLDERNFVCDLCDKRFNKRDELKKHHKNVHTEVPRSHVCPICTAAFKGKTTLKEHVKIHEEKTYKCQECGKTFAQHSGLYSHRKTHQKQRDTLLKDVMMMAEETTTSSIKIEILDDNDTI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00749948;
90% Identity: iTF_00748462;
80% Identity: -