Basic Information

Insect: Glossina morsitans
Gene Symbol: janA
Assembly: None
Location: scf7180000642139:7849-18014[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.022 1.2 9.2 0.6 2 23 187 209 186 209 0.96

2 16 3.2 1.7e+02 2.4 1.7 1 23 212 234 212 234 0.96

3 16 0.00047 0.026 14.5 1.2 2 23 241 262 240 262 0.97

4 16 0.0033 0.18 11.8 3.4 1 23 268 290 268 290 0.96

5 16 0.00036 0.02 14.8 4.4 2 23 298 319 297 319 0.97

6 16 1.1e-06 6.2e-05 22.7 2.6 1 23 326 349 326 349 0.97

7 16 0.029 1.6 8.9 0.6 3 23 413 434 411 434 0.91

8 16 0.0045 0.25 11.4 2.1 2 20 454 472 453 474 0.93

9 16 0.47 26 5.0 0.2 1 17 865 881 865 882 0.93

10 16 0.0014 0.078 13.0 0.8 3 23 982 1003 978 1003 0.92

11 16 0.00084 0.046 13.7 0.0 1 23 1008 1030 1008 1030 0.98

12 16 7e-06 0.00038 20.2 1.2 2 23 1037 1058 1036 1058 0.98

13 16 0.0013 0.072 13.1 1.2 1 23 1064 1086 1064 1086 0.98

14 16 0.00092 0.05 13.6 3.1 3 23 1095 1115 1093 1115 0.96

15 16 0.00041 0.022 14.7 6.2 1 23 1122 1144 1122 1144 0.97

16 16 0.047 2.5 8.2 1.1 1 23 1178 1201 1178 1201 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.022	1.2	9.2	0.6	2	23	187	209	186	209	0.96
2	16	3.2	1.7e+02	2.4	1.7	1	23	212	234	212	234	0.96
3	16	0.00047	0.026	14.5	1.2	2	23	241	262	240	262	0.97
4	16	0.0033	0.18	11.8	3.4	1	23	268	290	268	290	0.96
5	16	0.00036	0.02	14.8	4.4	2	23	298	319	297	319	0.97
6	16	1.1e-06	6.2e-05	22.7	2.6	1	23	326	349	326	349	0.97
7	16	0.029	1.6	8.9	0.6	3	23	413	434	411	434	0.91
8	16	0.0045	0.25	11.4	2.1	2	20	454	472	453	474	0.93
9	16	0.47	26	5.0	0.2	1	17	865	881	865	882	0.93
10	16	0.0014	0.078	13.0	0.8	3	23	982	1003	978	1003	0.92
11	16	0.00084	0.046	13.7	0.0	1	23	1008	1030	1008	1030	0.98
12	16	7e-06	0.00038	20.2	1.2	2	23	1037	1058	1036	1058	0.98
13	16	0.0013	0.072	13.1	1.2	1	23	1064	1086	1064	1086	0.98
14	16	0.00092	0.05	13.6	3.1	3	23	1095	1115	1093	1115	0.96
15	16	0.00041	0.022	14.7	6.2	1	23	1122	1144	1122	1144	0.97
16	16	0.047	2.5	8.2	1.1	1	23	1178	1201	1178	1201	0.92

Sequence Information

Coding Sequence: atggaaaatatGTTGAACAATAAAACTGTGTTTATACGCTGTTTTTTATGCCGCAAAAGGAACTCGAACGACAGAATACACAAAAGCGTTGATGCCGCTTTGTGTCCCGCATCGAAGAAGAGTATCAAAACGGTTTTGATGCATCTTGCCCGTTGTGGGAAATTTGAATTGCATATAACTTGTGGTGAATGGGTTTGCAGGCAATGTTATACATTAATTGCCGATTATGATGCCTGTTTGATTAGTATGACGCGAAAGCAAAGAAATCTAACGAATCTTGTTGAAAAAGCGGCAATTAGTGTTGACAGCGAATTCGAAGAAGAATGTCTAGAAGAGCTCGCTGCAATGGAAGAATTCAATGATGATCGCTTCTTCGACGACGTTAATGTAAGCGATAATGAAATAGCAGAAACTATGTACGAAGTTATGGGTAGCAGAAGAGCTAAGAAATTGAAATCTCAAGATGCTTTATTGCCTATCCCAGTGGAAGCTAAGTCGACCACGCCTTCACCGTCGTCACCATCTATTCAAAGATCCATAACACCCGTAGAAATTCTGCAATGCAATTTATGTGCAATGCGTTTTCAAAATAAAATACGTTTACAAAAACACGTGAACTCGGCGCATAAAAAATTCAGTTGCGATCTCTGTAGCTTTAGCCATCGCAACGAAGATTATATCATGTTACATATGAATTTGCATGAAGGTAAAAATGAAAATCAATGTCGTTACTGCAGTAAAGAATTCACCACAAAAATCAGCACAATACGTCATATGGAAGTGCATTTGGACACAAAGAAATATCAATGCGATAAATGTGGTTTATGCTTCTCGCAGACAACTGTCCTATACAATCATAAATTGCAACATGAAGCTGAAGAGAAGCCCTTACGTTGCGAGATATGCAATCAGATTTTTAAAACGAAACGTACCTTCCGCCATCATCGGATAACGCATCGAGTTGATCGGCCACGTTATAGTTGCGATTATTGTGGGAAAACTTTTACCGAGAAATATACATTAAAAGTGCACAAAAGATCCACTCATTCTGAAAGCGAATCGGTacagcagcaatcaacgacgacaacaacaacgacgacaacagcacaacatcaaaagcaaTGCTATCAGCTTGAAAAACACCAGCAACAACAATCCGATACTAATGAGAATATTGAATATGGCCAAACTACGCCTGTACTAAGTCAAACGTTTGGAAACGAAGCGAAACTTAGTTGCATTATATGTGATCTACCATTTTTAAGTAAAGAACACTTAAATAAACATATGGAGAAGGAACATGATGTCATCCTTAAATCGTTAACAGTCGCGAATTTCTCGCAAAACGAAACTCGAAAACCGTGTCACATATGTGGACAAATGTTTAGTGCCCATCATAATTTAGAATATCACTTAGAACATTTTCCAATACGTTTTGAAATGCTGAAAACCGTTGTTCGATTTTTCGCACGCGCTAAGAAAAGATTTGCTTTAGATTCAAATGCCGTCCCAAGTGTGGATATCGAGGAAGGCAGTTTCAAGTATGTCCTTATCAAGGTCAGCGATGAGGACAATTCCGATGATTCTGCGTCGTATAAGACAATAGTCAGAGGATATAAGGACTGCCAGGGGCATTCTGACATTTATGAACGCGTCCGGGCGTCCTGTAAGGTTATGGGATTGCAAGCCGAAATCCTAGGCGGTGGTAGAATCGATCGTGATTCATTAGCTAAAAGAATCAAAGTGTACGCTGTAAGAATTTTAACACGCCGTGCAAGAACGTATTCATTTCTATCAAACGCTGTCCCAAATGTGGATATCGAGGAGGGCCAATTCAAGTACGTCCTTATCAAAATCAAGGACAAGGAAAATGCCAGTTCCTTTGAAAAGATAATAGTCAGAGGATACAAGGACTGCCAGTGGCATTCTGACATCTATGAACGATGCAGTGCGCATTGCCAAGCAATAGGTTTGGAAACTGAAGTCTTAGGTGGCGGTAAAATCGAACATGATCCCTCAGCTaaaaaaaTCAAAGTATTCGGCGAGTCAACGGGTTACGGCAAAGCCGATCATGAAGAGACGAAGAAAATTTTGTTAACCCAATATCCCAATTATACAATTGAGGTTGCTGACAATGCCAGAAAATTTGCATTAAACTCAAAAGCGATTCCATGTGTGGATATTGAAGAAGGCATTTTTAAATATGTGCTTATCAAGGTATACGGTAAGGAGACATCGGATGGTTATGAGCCATTTAAAACGATAGTTAGGGGATACAAGGACTGTGCATGGCATGCTGATATATATGAACGTGTTAGTGCATCTTGCGAGGGCTTAGGCTTGGCAACCGAATGTTTAGGCGGAGGTAGAATCGAGCATAATCCTTCTGCTAAATTAATCAAGGTCTACGGTTATTCACAGAATATGGACTCTGCGATATTATGTTTTTTATGCACCAAAGACAGCAACCAGAATAGCGAATTTTACGATGTAAGCAGTGCTGTGGTACCAGCATCGCAGAAGCCACTTCATATAGTCTTACAACATTTGGCGAATCGTATTAAATTCAAATTAATCTTCCAAAATGGAACATTCGTTTGCAGTGAATGCTTTAAGGAGCTGAGTGATTATGATAATTTAATGCTCAATCTGCTCACATCTCAAAAACTTTTAACTAACCGATTACAAAATGCTTTAAACGATAAGCCCGAGGTAGTATCGGAAGATGGTCAGGATTACGAAATTGAATTGGAAGTTGAAGAAGATGCAACAATTGAAGATGCTTTTAATCCGGAATTAGATACAAAAGAAGAACTAATTGAAGTGGATGATAATGTTATCGTAGAAGAGTTCATAGATGACGGATCAAATAATAGCAATATTCCTACATCAAATGATGAAACCGAAAACGCAACGTCAGAACGAAAACGCTGTAAAAGAGAATGCTTGGCTTGTGAAGAAGTATTCAAATCAAATTATCAATTACAAAATCACATCAATGAAGTACACAACAATAGACAATTCATATGCAAGATATGTGGAGTAGCTCGTAAAGATGAGGAATACTTGGAATTGCATATGAACATACACGAGGGCAAGACAGAGAACCAGTGTCGCTATTGTACCAAGGTATTCTCACGTCCTGTAAACACATTGCGCCATATGCGTATTCATTGGGATAAAAAGAAATTTCAATGTGAGAAATGCGGCGAACGCTTTTCATTAGACAACATGCTTTACAATCATAGATTGCGACACGAAGCTGAAGAAAATCCGGTTATATGTAATTTTTGCAATCAATCTTTTAAGTCGCGCAAAACTTATAATCATCATCTTTTAATTCACCAAACAAATCGACCCCGCCATCATTGTGATCTATGCCCGAAATCATTTACTGAACGATACACTTTGAAAATGCATCGAAAGACACATAACGAGAACAATACTCCTACTCCTGTTGAGACAAAACCCGGCGACTTTAAAGAAACCGAAGCAGCCATAAATATATTGGTCGAGAGTATTGACAGAGAATTTCAATGCGTTATTTGTAATTTGAAGTTTGAAACTAAATCGGCGCATCTACAACATTTACAGGAAGAGCATGATGTTATTCCATAA
Protein Sequence: MENMLNNKTVFIRCFLCRKRNSNDRIHKSVDAALCPASKKSIKTVLMHLARCGKFELHITCGEWVCRQCYTLIADYDACLISMTRKQRNLTNLVEKAAISVDSEFEEECLEELAAMEEFNDDRFFDDVNVSDNEIAETMYEVMGSRRAKKLKSQDALLPIPVEAKSTTPSPSSPSIQRSITPVEILQCNLCAMRFQNKIRLQKHVNSAHKKFSCDLCSFSHRNEDYIMLHMNLHEGKNENQCRYCSKEFTTKISTIRHMEVHLDTKKYQCDKCGLCFSQTTVLYNHKLQHEAEEKPLRCEICNQIFKTKRTFRHHRITHRVDRPRYSCDYCGKTFTEKYTLKVHKRSTHSESESVQQQSTTTTTTTTTAQHQKQCYQLEKHQQQQSDTNENIEYGQTTPVLSQTFGNEAKLSCIICDLPFLSKEHLNKHMEKEHDVILKSLTVANFSQNETRKPCHICGQMFSAHHNLEYHLEHFPIRFEMLKTVVRFFARAKKRFALDSNAVPSVDIEEGSFKYVLIKVSDEDNSDDSASYKTIVRGYKDCQGHSDIYERVRASCKVMGLQAEILGGGRIDRDSLAKRIKVYAVRILTRRARTYSFLSNAVPNVDIEEGQFKYVLIKIKDKENASSFEKIIVRGYKDCQWHSDIYERCSAHCQAIGLETEVLGGGKIEHDPSAKKIKVFGESTGYGKADHEETKKILLTQYPNYTIEVADNARKFALNSKAIPCVDIEEGIFKYVLIKVYGKETSDGYEPFKTIVRGYKDCAWHADIYERVSASCEGLGLATECLGGGRIEHNPSAKLIKVYGYSQNMDSAILCFLCTKDSNQNSEFYDVSSAVVPASQKPLHIVLQHLANRIKFKLIFQNGTFVCSECFKELSDYDNLMLNLLTSQKLLTNRLQNALNDKPEVVSEDGQDYEIELEVEEDATIEDAFNPELDTKEELIEVDDNVIVEEFIDDGSNNSNIPTSNDETENATSERKRCKRECLACEEVFKSNYQLQNHINEVHNNRQFICKICGVARKDEEYLELHMNIHEGKTENQCRYCTKVFSRPVNTLRHMRIHWDKKKFQCEKCGERFSLDNMLYNHRLRHEAEENPVICNFCNQSFKSRKTYNHHLLIHQTNRPRHHCDLCPKSFTERYTLKMHRKTHNENNTPTPVETKPGDFKETEAAINILVESIDREFQCVICNLKFETKSAHLQHLQEEHDVIP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -