Basic Information

Insect: Glossina morsitans
Gene Symbol: zfh1
Assembly: None
Location: scf7180000652170:24270999-24279198[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 8.1e-06 0.00044 20.0 0.2 1 23 131 153 131 153 0.98

2 11 4.3e-07 2.3e-05 24.1 2.0 1 23 159 182 159 182 0.98

3 11 1e-05 0.00054 19.8 0.8 1 23 188 210 188 210 0.98

4 11 0.00059 0.032 14.2 2.7 1 23 216 238 216 239 0.94

5 11 4e-07 2.2e-05 24.2 2.2 1 23 246 268 246 268 0.98

6 11 0.00065 0.036 14.0 2.1 1 23 274 297 274 297 0.95

7 11 0.097 5.3 7.2 0.1 2 23 304 324 303 324 0.94

8 11 0.00012 0.0063 16.4 3.9 1 23 330 352 330 352 0.98

9 11 0.0024 0.13 12.3 4.7 1 23 358 380 358 380 0.99

10 11 0.012 0.67 10.0 0.9 2 23 387 412 386 412 0.84

11 11 0.00049 0.027 14.4 0.3 1 21 418 438 418 439 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	8.1e-06	0.00044	20.0	0.2	1	23	131	153	131	153	0.98
2	11	4.3e-07	2.3e-05	24.1	2.0	1	23	159	182	159	182	0.98
3	11	1e-05	0.00054	19.8	0.8	1	23	188	210	188	210	0.98
4	11	0.00059	0.032	14.2	2.7	1	23	216	238	216	239	0.94
5	11	4e-07	2.2e-05	24.2	2.2	1	23	246	268	246	268	0.98
6	11	0.00065	0.036	14.0	2.1	1	23	274	297	274	297	0.95
7	11	0.097	5.3	7.2	0.1	2	23	304	324	303	324	0.94
8	11	0.00012	0.0063	16.4	3.9	1	23	330	352	330	352	0.98
9	11	0.0024	0.13	12.3	4.7	1	23	358	380	358	380	0.99
10	11	0.012	0.67	10.0	0.9	2	23	387	412	386	412	0.84
11	11	0.00049	0.027	14.4	0.3	1	21	418	438	418	439	0.94

Sequence Information

Coding Sequence: ATGGTGCGCAGTCGCCGTTCCATTTCGAAAGAGGACGCTTCCTCGGTTTTAACAGACAGTGGAATTTCATTGTCTTCACCATCGTCAAATCAAACGCGATTTCCGTCTCACCATCATCTCAGCGAAGACGAAGAGGAAGCTATTCTCAATAAATTGTTTGTAACGGATGAAGAAAATACGATCCAGCGTACAACAGATGATCCCACTGTGTCAAAACGTTCTATCGAAAAGGTTGTGGGCAGTGATAGTGAAGATAATCAGTTGGCAGCAGAAGATAAGAGGAATGGCAAAGATGAAAAAGAGAATAAAACTGAAATAAACGCAACGGTTGCACAAAACGATTGTAAACCGGTTGTGGGTGCGCCAGCCGGCAAAAGATCACGCAAATCATACGTTTGCGAAGTCTGCAATAAAGAGTTTGGCGGCAATACTGATCTCAAACGCCATCAATTGATACACTCCGATGAGAAACCTTTCAAATGTGAACAATGCGGTAAGTGCTATCGTCAAGCCATCAATCTTAAAAATCACATTACAACGGCTCACGCTAGAAAGAAACAGTATTCTTGTGATCAATGTCCGAAAACGTTTGCGCTGAAGGAACGTCTTAAACTGCATATGCGTTTGCATTCTGGTGAAAAGCCTTACGCTTGCAGTCAGTGTGATAAACGTTTTGCTCGCGGTGGTCAGCTACACCAGCATACGGTTAGTCATCATCAGGATGCTCCGAAGAAATTCAAATGTGAAAAATGTTCGACACGATTTTCGACCTCCTCAAATTTAAAAGCTCACTTGGAACGGCATGAACACGGACCAGAACATTATTGCAATATCTGTAATGAGCACTTCGTCAATGAAGTGTTACTTAAAACCCACGTGGCAAAGACGCACTACAAACTGAAGCAGGTCGAATGTGAAGTATGCAAGCAAACTATAGAAGAAGAAGACTTGGCTACGCATATGAAAACTCATGCCAATGTAAAGAGTCACGTGTGCGAAGTGTGCCATTCAATGTTTATGCAAAAATCACAATACAATGTACATATGAGAATGCATACGGGCGAACGTCCCTATCAATGCCAGGTGTGCTGTCAAACTTTTGCTCATTCGAGTGTTTTAAAATTACACATACGTAAACACACCGGAGAAAAGCCCTTCAACTGCTTATTGTGTAAAGATGATGAGGTAGCGTTTTCTCAGTTGGCCCATCTGAAAACGCACATGAAAAAGATACACAATCAATTTAAGCCTTATATGTGTGAGGGTTGTCATGAATTTTTTAAAGTCAAAATTGAATTAGAAGCTCATCAACATCGCTGCGATAAGTGTACATCCAATTTAGACGAACAGGATGCGCGCTACAATGAAGCGCAAATATTATCGCATATACGCTTCCATATGGCTATATTACTCaaaaaaaTTTCGTCCAATCAGAAATTGCAGCAGTTAGGCTTTGAGAAACGACTCATAGATAATGTGATTATGGCTTCATTGAAATTGGCTAAACGAAAAGTACACGATGATCCTAATTTAACACCCATTGAACGCATGCGTCTAAATGTGCAAGAGCTACTTAATTGGATAGTGCCAATAAAAGTAATGGAGACATTTCGTGAGGAGAAACTCTCAGTGGAAAATATATTAGAAAAGATAGTTACCATGTATATGAAACAAAAGTAA
Protein Sequence: MVRSRRSISKEDASSVLTDSGISLSSPSSNQTRFPSHHHLSEDEEEAILNKLFVTDEENTIQRTTDDPTVSKRSIEKVVGSDSEDNQLAAEDKRNGKDEKENKTEINATVAQNDCKPVVGAPAGKRSRKSYVCEVCNKEFGGNTDLKRHQLIHSDEKPFKCEQCGKCYRQAINLKNHITTAHARKKQYSCDQCPKTFALKERLKLHMRLHSGEKPYACSQCDKRFARGGQLHQHTVSHHQDAPKKFKCEKCSTRFSTSSNLKAHLERHEHGPEHYCNICNEHFVNEVLLKTHVAKTHYKLKQVECEVCKQTIEEEDLATHMKTHANVKSHVCEVCHSMFMQKSQYNVHMRMHTGERPYQCQVCCQTFAHSSVLKLHIRKHTGEKPFNCLLCKDDEVAFSQLAHLKTHMKKIHNQFKPYMCEGCHEFFKVKIELEAHQHRCDKCTSNLDEQDARYNEAQILSHIRFHMAILLKKISSNQKLQQLGFEKRLIDNVIMASLKLAKRKVHDDPNLTPIERMRLNVQELLNWIVPIKVMETFREEKLSVENILEKIVTMYMKQK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00746895;
90% Identity: iTF_00746895;
80% Identity: -