Gfus016721.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Glossina fuscipes
Gene Symbol
grau
Assembly
None
Location
Scaffold356:274069-290747[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 0.25 20 6.0 1.9 2 23 269 291 268 291 0.93
2 29 0.084 6.8 7.5 2.5 6 23 300 317 300 317 0.99
3 29 0.0039 0.31 11.7 2.1 1 23 323 346 323 346 0.95
4 29 0.0046 0.37 11.5 2.8 1 23 354 377 354 377 0.91
5 29 0.031 2.5 8.9 0.2 2 23 398 420 397 420 0.95
6 29 0.086 7 7.5 0.3 6 23 429 446 429 446 0.98
7 29 0.0015 0.12 13.0 0.4 1 23 452 475 452 475 0.96
8 29 0.088 7.1 7.4 0.8 1 23 483 506 483 506 0.94
9 29 0.016 1.3 9.8 0.3 2 21 512 531 511 532 0.94
10 29 0.38 30 5.5 2.1 2 23 801 823 800 823 0.93
11 29 0.033 2.6 8.8 1.2 6 23 832 849 832 849 0.99
12 29 0.028 2.2 9.0 1.3 1 23 855 878 855 878 0.94
13 29 0.00014 0.011 16.3 1.2 1 23 886 909 886 909 0.95
14 29 4.9 4e+02 1.9 0.1 2 23 930 952 929 952 0.88
15 29 0.0068 0.55 10.9 1.3 6 23 961 978 961 978 0.99
16 29 0.00091 0.073 13.7 1.8 1 23 984 1007 984 1007 0.96
17 29 0.019 1.5 9.6 0.2 1 23 1015 1038 1015 1038 0.91
18 29 0.024 1.9 9.2 0.2 2 21 1044 1063 1044 1064 0.95
19 29 0.0083 0.67 10.7 3.0 3 23 1068 1088 1066 1088 0.97
20 29 0.12 9.3 7.1 0.1 2 20 1100 1118 1100 1119 0.93
21 29 9.3 7.5e+02 1.1 1.8 2 23 1411 1433 1410 1433 0.92
22 29 0.015 1.2 9.9 1.3 6 23 1442 1459 1442 1459 0.99
23 29 0.0055 0.44 11.2 1.2 2 23 1466 1488 1465 1488 0.94
24 29 0.0022 0.17 12.5 0.7 1 23 1496 1519 1496 1519 0.95
25 29 0.011 0.87 10.3 0.6 2 23 1540 1562 1539 1562 0.94
26 29 0.11 9 7.1 0.1 6 23 1571 1588 1571 1588 0.98
27 29 0.011 0.89 10.3 0.5 2 23 1604 1626 1603 1626 0.95
28 29 0.16 13 6.6 0.3 1 23 1634 1657 1634 1657 0.91
29 29 0.0037 0.3 11.8 0.3 2 21 1663 1682 1663 1683 0.95

Sequence Information

Coding Sequence
ATGGAAGCAACAATGATTTGTCGCTTGTGCTTAAAAGAGGTTAATGAATTTAAAAGTGCGTTTGCCGTGACGGAGAATAAACCAACCATGGCTTCAGTAGTCAGAATTCATTTCTGGTTTGAGCTGCAACAAAACGATCCCATATCAACAGTAATTTGCAATAGTTGTTGGTGTAAGGTTTCCGATTTCCATGACTTCTATAAAAGCGTTGAGGAAGCTCAGAGTCATCTGGGAGAAAATGTCACAGTGAAAATTGAGAACATTAGCGCGGAGCATTCCATAGAAAATGTGATGATTCCATCATTTTCATTGTCGAGTAAACAGGAACCCGAAGTCAATTTCGACGAAGTTAATGATGAAGTTCCTTTTGACATGACGACGGTTGAAACGCCTAGTACGCGTACAGGTCTCAGAACCGACGACTCCCATGACATATGGAGAAGCCaaaaaaaCAGTGATAACAATGCCATTGAGGATATCAAAGACATCATTGACTATAAAGATGAAATATTCAGTGATCATAACTCCGACCCGGTTAACAGAACAACTTTTGCAgaaaatgaagaaagtaataaagtaaccataaacaaaaaaggaataaataaaactaataaatTGTCAGTTAAGGCACAACGGAAAGTCCCGCTAGCACAGAAAATTCATTGCAAAAACGGACGTGCAGCAAAAGTGCCTGAAGTAGAAAAGAGCAATGTCaaaaaaaCGAAGGAACTCTCTGAACAAGCTAAAGCTATTCGTGAGCAGGGTTTAGCCTTTGACGGAGAAATCGCCAAGTTTATGTCATTGCATTGCGAACTTTGTAAAGTAACGGCTACGAATTTTAGCTCCCTTCATACCCACATGCTTGCAGAACATAAAATCAATGGTTACGTGAGATGTTGTAATAAGAAATTTTCGAAACGTTTCGCACTTCTGGATCACATACGACATCATTCAAATCCTGAGCGTTTCAAATGTGAGCAATGCAATCGTGTTTACGCTAATCGAAATTCAATGCGCACTCATTTCCTTAGCAAGCACAAAAACGACAAAGAGAAAGTATTTACTTGTTCTCAGTGCCCTCAGAAATTTTTCAAAAAGTATTTACTAAGAAAACATGAACTGTTCGGGCATAGTGATCATAAAAACGCCTGCATAGCCGTCGATGAGGAGATAGCCAATTTTATGCCATTGCGTTGTGAGCTGTGCAATGAGGAGTCTACCAATTTTACAGCTCTTAAAGGACACATGCGTGATGAACACAACGTCAAAGGCTACGTCCGATGTTGTAATAAGAAATTTTCTGAGCATGGTTTACTTGTTGAGCACATACGCGCCCATTTAAATCCTGCATGTTATAAATGTGAAGAATGTAGTCTTGTCTTTCCCGATCGCCAGTCTATGCGCAATCATTTCCTTATGGAACACGGAAAGATGGAAGATAAACCCTTTGCTTGCTCTCTGTGCTCTAGCAAATTTGTTACAGTATATTTGTTACATCGACATACAGCAGTTGTTCATGGTGACCATAGCAAAACCTGCAGCAGTTGTCGGAAAAAATTTGAAACTGCCGCTCAATTATCGGCTCATGTTAAGGAACAATGCTTATGTGATACATGCGCGGAAGTTGTTAATGAATTTAAAAGCGCGTTTGAAGTAACGGATAATAAACCAACCATGGCTTCAATAATCAAAAAACACTTTTGGTTTGAACTGCAGCAAAACGATCCAGTATCAACAGTAATTTGCGATGATTGTTGGTTTAAAGTTTTTGATTTTCATGAGTTTTATAAAACCGTTGAAAAAGCTCAATGTCAGTTGGGCGAAAATGTCGTAGTGAAAATTGAAAACATTAGCGCGGAGCATTCCATAGAAAACGTGATCATCCCGTCATTTTCATTGTCGAGTAAACAGGAACCTGGTGTTAACTTCGACGAAGTTAATGATGAAGTTCCTTTTGATATGGTCGCGACGAATGACAACACGCGTGCAGATGTCAGAGCAGAGGATTCCCACGATATATTGGGAACTCAACAAGGTTGTACTAATAACGCCATAGAGGATGTTAAACATGTCGATGTTTACAAGGATGATAGATTTAATGATCACATTGATGATCCATTTAACAAAGAAGTGTTAGCagaaaatgagaaaaataataaagtaagcaaaaagaaaaaaggtgtaaaatcttcagaaaagGCTAGAACCACCAGATCTTCGTCTAAGGTACAAAGGGACGCACAGAATATTCGTTCCTCAAAACCAGCTGCAACAAAAGTTCGCAAGATTGAAAAGAACAGGGTCaaaaaagtgaaaaaaaaaGAACTTTCCGAACAAGCTAAAGCTATTCGTGAGCAAGGTTTGGCATTTGATGAAGAGATTGCGAAATTTATGTCTTTGCGTTGCGAGCTATGTAGCCTTGAAGTAAAAAATTTTCATGACCTTGAAAGCCATATGCACGCAAAACACAAAGTCAAAGGATACGCCCGATGTTGCAATAAGAAATTTTCTAAGCGCTTTTTACTGCTGGACCACATACGCCAACATTCAAATCCCGATTGTTTCAAATGCGATCCATGTAAGCGGGTTTTCGCAGACCGTAAATCTATGCGAAATCATTTCCTTATCAAACATCAAAAGGATGAGGATAAAATGTTCTCCTGCTCACAATGTTCCAAGAAATTTGTTAGAAGATATTTATTACGACAGCATGAATTAGTGGGTCATAGCGACCATAAAAACGCTTCTTTAGCTGTTGATGAGGAAATAGCCAAATTTATGTCATTACATTGTGAACTATGCAGCGTGGAGATAGCAAATTTTACCGCTCTTCGCAATCATATGGTCGCAGAGCACAACATCAAAGGTTACGTGAGATGTTGTAATAAGAAATTTTCCAAACGTTTTTTACTTTTGGAGCACATACGAACGCATTTAAATCCTGCTTGCTACAAATGTGAGAACTGTAGTCGTGTATTTCCCGATCGTAAGTCCATGCGTAATCATTTTCTTATGAAACATCAAAAGGACGAAGACAAAACATTTGCTTGTTCTCAGTGTCCCAGCAAATTTGTTACCGTGTACCTATTACAGCGACACAAAGTGATTGCGCACCGTGATCGTACCAACACTTGCAAAAGTTGTAACAGAAGATTTAGTACAGGTGTTCTGTTGTCTGCTCATATCAAGGAGCAGTGTTTATGCGATACGTGCGGGAAAGTTGTGTGTAACACTGCTGCGTTTCAACGTCATCTATTGAGACATAAAAACTGCCTTTCGGAATCCAAAGAATTGCGCACCTGTGATATTTGCCAAAAGGTATCAACAAGTCAACAAGACATGTTGGCTCACAAACTTTGTGCTCATAATCCCTTACGTACTTACGAATGCAATACGTCCTCTATGCACGATAACTTTCCATTTCAATATCCATATGCAATCACATCCCAAGAAAATGCATCCACAATGCTCGCAATGATTTGCCGCTTATGTTTACAAGAAAGTTGTGATTTTAAAAGTGCATTTGACTCGGCAGACAATGAACGGACTATCGCTTCAATTATTGAAAAGTATTTCTGGTTTGAGTTCCAGCAAAACGATCCAGTATCAACAGTGATTTGTAACAATTGTTGGCTTAAAGTTTCTGACTTTCATGAATTCTATAAAAGTGTTGAAGAGGCCCAAAGTCATCTGGGCGAAAATGTCGTAGTGAAAATTGAAAATATTAGTGTGGAGCATTCCATAGAAAATGTAATAGTTCAGTCGATCCCTTTTTCTAGCAAGCAAGAGCCCAACGATTTTGCAGAAGCCAATGATGAGGACCCTTTTGATATGCCAATAGATAGAGTAGATAATAATCCGTCATCATTACTAAAGGGAAAAGATTCCAATGATAAATTAAGGAGACAAACTTATGGTATTAATTCTATGGAAACGGTTGAGAATGTCGGTGATGACAAAGACGAAAAATCTAGTGGTCATAACGGCAGAAAAGCAGCAGTTAAGAAGTCTTTGAAAAAGAAAAAGCCCATTAAATCTGCCACAACGGGTAGAACTaaaaaaaaTCCTATGCCTAAATTACAACGGAATGTAAACTTATGCTTAACgaaaaatacaagaaagttgggcaaaactgaaaacaacaactcaaaaaaagaaaaagtcaaaaaacCGATTGAAGATCCGAAAAGTATAGCTTTCGATGAAGAGATAGCTAAGTTTATGTCGTTACATTGTGATCGGTGCAAATTAGAGGCCAAGAATTTTAATGCTCTGCACAGTCATATGCTCGCAGAGCATAACGTTAAAGGTTACGCAAGATGTTGCAATAGGAGATTTTCTTCACGCTTTTTATTACTTGATCATATACGCCGACATTCTAATCCTGACAGTCTGAAATGCGAGCCATGTAATCGTATTTTTGCCGATCGCAATTCTCTGCGCCACCATTTACAAATCAAACATCAAAAAGATGAAGATAAAATGTTTTCCTGCTCTCGATGTCCAAAAAAGTTTGTTAAAATGTATTTGTTGCGACAACATGAGCTTGTCGGCCATAGCGATCATAAAAACGCTTGTCTGGCTGTTGATGAAGAGATAGCCAAGTTTATGTCGCTGCATTGTGAACAATGCAATGAAGAGGCGACCAACTTTACAGCCCTTAATCGGCATATGCGTGCTGAACACAACGTGCGAGGCTACGTCAGATGTTGTAATAGGAAATTTCGTGAGCGTGGTTTGCTTGTTGAGCACATACGCGCACATTTAAATCCTGCTTGTTACAAGCAAGTATATCCATTTTTAAGGAAAACATGTGAGGAGTGTAGTCTCGTTTTTCCGGACCGTAAGTCGATGCGTAATCATTTTCTTATGATTCATCAAAAGGAGGAAGACAAACCTTTTGCTTGTTCTCAGTGTTCCAACAAATTTGTTACAGTATACTTGTTACAATTACATAAAGTGGTTGCTCATGGCGACCCTACAAATACTTGCAAAAGCTGTAGCAGAAAGTTCAATACTTCAGCTGAACTCTCGGCTCATATCAAGGAGCAATGCCTGTGTGATACATGCGCGGAAGTTATATGTGGAGTTGCTGCTTTTCAAAATCATATGCTCGGTCATGAGAAAAGTCTTACGGGTTCAAAAGGTTCCCATGTTTATACTCACAATCCTATACGTAGTTATGAATGCAAAGTCTCCTCCTCCTCATTGCATGACAATTTTCCATTTCCAGAAAACACTTCGAAAACTGCGCATGCATACCCGAGCGAACCGATTTCATCAAATCGTCATTGA
Protein Sequence
MEATMICRLCLKEVNEFKSAFAVTENKPTMASVVRIHFWFELQQNDPISTVICNSCWCKVSDFHDFYKSVEEAQSHLGENVTVKIENISAEHSIENVMIPSFSLSSKQEPEVNFDEVNDEVPFDMTTVETPSTRTGLRTDDSHDIWRSQKNSDNNAIEDIKDIIDYKDEIFSDHNSDPVNRTTFAENEESNKVTINKKGINKTNKLSVKAQRKVPLAQKIHCKNGRAAKVPEVEKSNVKKTKELSEQAKAIREQGLAFDGEIAKFMSLHCELCKVTATNFSSLHTHMLAEHKINGYVRCCNKKFSKRFALLDHIRHHSNPERFKCEQCNRVYANRNSMRTHFLSKHKNDKEKVFTCSQCPQKFFKKYLLRKHELFGHSDHKNACIAVDEEIANFMPLRCELCNEESTNFTALKGHMRDEHNVKGYVRCCNKKFSEHGLLVEHIRAHLNPACYKCEECSLVFPDRQSMRNHFLMEHGKMEDKPFACSLCSSKFVTVYLLHRHTAVVHGDHSKTCSSCRKKFETAAQLSAHVKEQCLCDTCAEVVNEFKSAFEVTDNKPTMASIIKKHFWFELQQNDPVSTVICDDCWFKVFDFHEFYKTVEKAQCQLGENVVVKIENISAEHSIENVIIPSFSLSSKQEPGVNFDEVNDEVPFDMVATNDNTRADVRAEDSHDILGTQQGCTNNAIEDVKHVDVYKDDRFNDHIDDPFNKEVLAENEKNNKVSKKKKGVKSSEKARTTRSSSKVQRDAQNIRSSKPAATKVRKIEKNRVKKVKKKELSEQAKAIREQGLAFDEEIAKFMSLRCELCSLEVKNFHDLESHMHAKHKVKGYARCCNKKFSKRFLLLDHIRQHSNPDCFKCDPCKRVFADRKSMRNHFLIKHQKDEDKMFSCSQCSKKFVRRYLLRQHELVGHSDHKNASLAVDEEIAKFMSLHCELCSVEIANFTALRNHMVAEHNIKGYVRCCNKKFSKRFLLLEHIRTHLNPACYKCENCSRVFPDRKSMRNHFLMKHQKDEDKTFACSQCPSKFVTVYLLQRHKVIAHRDRTNTCKSCNRRFSTGVLLSAHIKEQCLCDTCGKVVCNTAAFQRHLLRHKNCLSESKELRTCDICQKVSTSQQDMLAHKLCAHNPLRTYECNTSSMHDNFPFQYPYAITSQENASTMLAMICRLCLQESCDFKSAFDSADNERTIASIIEKYFWFEFQQNDPVSTVICNNCWLKVSDFHEFYKSVEEAQSHLGENVVVKIENISVEHSIENVIVQSIPFSSKQEPNDFAEANDEDPFDMPIDRVDNNPSSLLKGKDSNDKLRRQTYGINSMETVENVGDDKDEKSSGHNGRKAAVKKSLKKKKPIKSATTGRTKKNPMPKLQRNVNLCLTKNTRKLGKTENNNSKKEKVKKPIEDPKSIAFDEEIAKFMSLHCDRCKLEAKNFNALHSHMLAEHNVKGYARCCNRRFSSRFLLLDHIRRHSNPDSLKCEPCNRIFADRNSLRHHLQIKHQKDEDKMFSCSRCPKKFVKMYLLRQHELVGHSDHKNACLAVDEEIAKFMSLHCEQCNEEATNFTALNRHMRAEHNVRGYVRCCNRKFRERGLLVEHIRAHLNPACYKQVYPFLRKTCEECSLVFPDRKSMRNHFLMIHQKEEDKPFACSQCSNKFVTVYLLQLHKVVAHGDPTNTCKSCSRKFNTSAELSAHIKEQCLCDTCAEVICGVAAFQNHMLGHEKSLTGSKGSHVYTHNPIRSYECKVSSSSLHDNFPFPENTSKTAHAYPSEPISSNRH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-