Basic Information

Insect: Glossina brevipalpis
Gene Symbol: -
Assembly: GCA_000671755.1
Location: Scaffold166:62694-65914[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 2e-06 0.00012 22.0 1.6 1 23 255 277 255 277 0.97

2 9 8.2e-08 5e-06 26.4 2.0 1 23 283 305 283 305 0.98

3 9 9.9e-06 0.00061 19.8 3.1 1 23 311 333 311 333 0.98

4 9 0.0027 0.17 12.1 6.1 1 23 339 361 339 362 0.95

5 9 0.00014 0.0086 16.2 3.8 1 23 375 397 375 397 0.97

6 9 0.00062 0.038 14.2 4.5 1 23 468 490 468 490 0.97

7 9 0.026 1.6 9.0 0.2 1 23 499 522 499 522 0.91

8 9 0.00052 0.032 14.4 0.2 2 23 531 553 530 553 0.96

9 9 0.21 13 6.2 0.4 1 23 555 578 555 578 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	2e-06	0.00012	22.0	1.6	1	23	255	277	255	277	0.97
2	9	8.2e-08	5e-06	26.4	2.0	1	23	283	305	283	305	0.98
3	9	9.9e-06	0.00061	19.8	3.1	1	23	311	333	311	333	0.98
4	9	0.0027	0.17	12.1	6.1	1	23	339	361	339	362	0.95
5	9	0.00014	0.0086	16.2	3.8	1	23	375	397	375	397	0.97
6	9	0.00062	0.038	14.2	4.5	1	23	468	490	468	490	0.97
7	9	0.026	1.6	9.0	0.2	1	23	499	522	499	522	0.91
8	9	0.00052	0.032	14.4	0.2	2	23	531	553	530	553	0.96
9	9	0.21	13	6.2	0.4	1	23	555	578	555	578	0.95

Sequence Information

Coding Sequence: ATGAATCTTAAAAGCTTCCTAGTTAAGGTGAATAGCGACTTTAAAGAAGTATTACAGAACAAAAAAGACAAAGTGAAACATGATGATTTGTCAGTTGATGAAGAAATGCTTAGATTATTAGATCAAAATGAGGAAGAGAATGATAATGAAAACAAATTTGCGACGAGAAGTTCTCGAAAAACACCTGATTCCACCGAGAAAACATTTGAACAATCATGTGGTCATCAGCAGCAAGATTTAAGAAAAATTGAGCTTAACATGAAGTTAGCAAAAGATGACGAGCAATATCAGTATGCGAGCGATATGGTCACTGATTTTGAAGAAGAAGAACGTTTATCAGTGGATGAAATTGCGCCAGAAGAGTCTTTCGAAAAACAAGAAGGATTTGTGTATGAAGACAGTCAAGATTGCGTTAATGTGGAGACTGAAGAACAACCGCCTGAAACTGAATATGCAAACCATAACGAAGTTGAAGAAGATAAAATTATTGGGAAACGAAACGAACAAAATTTAAATGACGGTTATCTGCGAGTATACGAAGCGATGCTTCAGGTAAATAGTTTACATAATAATACTTGCGCCGACGACACTTCCTCTGTCGATGCTGTGTCCATTCACAGTAATATCATAGAAATAGATTCCAAAGTAATGGAAGCTGAATTAGAGGATAGCAATACACAATCCTCTTCCATAGTTGAAAAAAGCAAATCACGTAAGACTTCAAATAATAATAATAAGTCTGTTAACGCCTATTTACCGCGTTTCTATTGCGCCCAATGTAATCGAGATTTTAGCACCAAAACTAATTTAAATCGTCATATGTCAGCTCATGCCGGCAATAAACCGTACGTCTGTAATACCTGCAATAAAAGTTTCTCTCAGAACGGCTCCCTTAAACAACACATGTATACGCATACCGGTGAGAAACCGTTTGTTTGTGAGATTTGTGATCGAGGTTTCACTCAATGCAAAAACCTAATATATCACAAACGTAGGCACACCGGTGAGCTGCCGTTTCAATGTGATCATTGCCGCGGTACATTCCGTCAGAAAGACGCTTTAAAGGTCCACTTTTTTAAACATCATATGATTACAGAAACAACCTCCGATGGCCAATCGACTTATACGTGCACTATTTGCCAGAAAAGTTATCACAATAAAGCAGACGTACAAAAACATATGTTTTATCACGTTAACAATAAAAATAACTTTGTCCTGACTGATGCCGAGACCATGCAACAGGAAATTGAAGATGAAGTCCAAGATAGTATTTTGCCGGATAATTTGAATGCAAACTTTTTAGTTAAAGAAATGGATGTGAGCGATGTAGTTCTTACAAAGGCAAATTGTGTTGTAGACGTTAGCGCTAGCTCAGCTGCCGAACCCAGTCGTGCTAAACGTTTTAAATGCCGTAAATGTTTTAAATGCTTTGCAATCAAAAAAAATCTTTTACGTCACTTAGCTTTACACGATATTACTGTGGATATCATTAAATTTCCTTGTGCCTTTTGTGATTTAACTTTCGATACAAAGTATGCTGCCTACGCTCATCGTGCTCAGCAACATGCGAACATGGCTGGCAGTCCTATACAATGCAACGATTGCAATATGGAATTTTCAACAATGAACGGTTTAATGGAACATTTAAGCAAATTGCATCAGTATCAATGTGTCGACTGTCCAAATGTAAATTTTCAATCATTGAATGATTTAAAGAATCATACGTTATACCATAACTTTGAAGAAACGGaataa
Protein Sequence: MNLKSFLVKVNSDFKEVLQNKKDKVKHDDLSVDEEMLRLLDQNEEENDNENKFATRSSRKTPDSTEKTFEQSCGHQQQDLRKIELNMKLAKDDEQYQYASDMVTDFEEEERLSVDEIAPEESFEKQEGFVYEDSQDCVNVETEEQPPETEYANHNEVEEDKIIGKRNEQNLNDGYLRVYEAMLQVNSLHNNTCADDTSSVDAVSIHSNIIEIDSKVMEAELEDSNTQSSSIVEKSKSRKTSNNNNKSVNAYLPRFYCAQCNRDFSTKTNLNRHMSAHAGNKPYVCNTCNKSFSQNGSLKQHMYTHTGEKPFVCEICDRGFTQCKNLIYHKRRHTGELPFQCDHCRGTFRQKDALKVHFFKHHMITETTSDGQSTYTCTICQKSYHNKADVQKHMFYHVNNKNNFVLTDAETMQQEIEDEVQDSILPDNLNANFLVKEMDVSDVVLTKANCVVDVSASSAAEPSRAKRFKCRKCFKCFAIKKNLLRHLALHDITVDIIKFPCAFCDLTFDTKYAAYAHRAQQHANMAGSPIQCNDCNMEFSTMNGLMEHLSKLHQYQCVDCPNVNFQSLNDLKNHTLYHNFEETE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00746919;
90% Identity: -
80% Identity: -