Basic Information

Insect: Glossina austeni
Gene Symbol: grau
Assembly: GCA_000688735.1
Location: Scaffold166:612876-615776[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.062 4.7 8.0 2.2 2 23 269 291 268 291 0.93

2 10 0.025 1.9 9.2 2.5 6 23 300 317 300 317 0.99

3 10 0.0011 0.086 13.5 2.1 1 23 323 346 323 346 0.95

4 10 0.0014 0.1 13.2 2.8 1 23 354 377 354 377 0.91

5 10 0.025 1.9 9.2 0.1 2 23 398 420 397 420 0.95

6 10 0.072 5.4 7.8 1.0 6 23 429 446 429 446 0.98

7 10 0.00044 0.034 14.7 0.4 1 23 452 475 452 475 0.96

8 10 0.026 1.9 9.2 0.8 1 23 483 506 483 506 0.94

9 10 0.0042 0.32 11.7 0.3 2 21 512 531 511 532 0.94

10 10 0.47 36 5.2 1.6 3 23 536 556 534 556 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.062	4.7	8.0	2.2	2	23	269	291	268	291	0.93
2	10	0.025	1.9	9.2	2.5	6	23	300	317	300	317	0.99
3	10	0.0011	0.086	13.5	2.1	1	23	323	346	323	346	0.95
4	10	0.0014	0.1	13.2	2.8	1	23	354	377	354	377	0.91
5	10	0.025	1.9	9.2	0.1	2	23	398	420	397	420	0.95
6	10	0.072	5.4	7.8	1.0	6	23	429	446	429	446	0.98
7	10	0.00044	0.034	14.7	0.4	1	23	452	475	452	475	0.96
8	10	0.026	1.9	9.2	0.8	1	23	483	506	483	506	0.94
9	10	0.0042	0.32	11.7	0.3	2	21	512	531	511	532	0.94
10	10	0.47	36	5.2	1.6	3	23	536	556	534	556	0.96

Sequence Information

Coding Sequence: ATGGAAGCAATAATGATTTGTCGCTTGTGTTTAAAAGAGGTTAATGAATTTAAAAACGCGTTTGCTGTGACGGAGAATAAACCCACCATGGCTTCAGTAATCAGAATACATTTCTGGTTTGAGCTGCAGCAAAACGATCCCATATCAACAGTAATTTGCAATAATTGTTGGCATAAGGTTTCCGATTTCCATGACTTCTATAAAAGCGTAGAGGAAGCTCAAAGTCACTTGGGAGAAAATGTCACAGTGAAAATTGAGAACATTAGCGCGGAGCATTCCATAGAAAATGTGATGATTCCGTCATTTTCATTGTCCAGTAAACAGGAACCTGAAGTCAATTTCGACGAAGTTAATGATGAAGTTCCTTTTGACATGATGACGGTTGAAACGCATAGTACGCGTACAGATCTAAGGACCGACGATCCCCAAGATGTATGGAGAAACCAAAACAACAATGATAATAACGCCATAGAGGATGTTAAGGACGTTATTGACTACAAAGACGAAGTCTTCAATGAGCATAAGTCCGACCCGGTTAACAAACCAATTTTTGCAgaaaatgaagaaagtaataaacaaaccgtaaacaaaaaaggaataagtaaaactaccaaatTGTCAGTTAAGACACAACGGAATGTCCCGCTAGCACAGAAAATTCATTGCAAAAACGTACGTGCAGCAAAAGTGCCTGAAACAGAAAAGAACAACGTCaaaaaaaCGAAGGAACTTTCTGAACAAGCTAAAGCTATCCGTGAGCAGGGTTTAGCCTTTGATGGAGAAATAGCCAAGTTTATGTCATTGCATTGCGAACTGTGTAAATTAACGGCTACGAATTTTAGCTCCCTTCATACTCATATGCTCGCAGAACATAAAATCAATGGTTATGTGAGATGTTGTAATAAAAAATTTTCAAAACGTTTCGCACTTCTGGATCACATACGGCATCATTCAAATCCTGAGCGTTTCAAATGTGAGCAATGTAATCGTGTTTATGCTAATCGTAATTCAATGCGCACTCATTTCCTTAGCAAGCATAAAAACGACAAAGAGAAAGTTTTTACTTGTTCTCAGTGCCCTCAGAAATTTTTTAAAAAGTATTTACTAAGAAAACATGAACTGTTTGGACATAGTGATCATAAAAACGCTTGTATAGCCGTCGATGAGGAGATAGCCAATTTTATGCCATTGCGTTGTGAACTGTGCAATGAGGAGGCTACCAATTTTACAGCTCTTAAAGGTCACATGCGCGATGAACACAACATCAAAGGCTACGTCAGATGTTGTAATAAGAAATTTTGTGAGCATGGTTTACTTGTCGAGCACATACGCGCCCATTTAAATCCTGCATGTTATAAATGTGAAGAATGTAGTCTTGTCTTTCCCGATCGCCAGTCTATGCGCAATCATTTCCTTATGGAACACGGAAAAATGGAAGATAAACCTTTTGCTTGCTCTCTGTGTTCTAGCAAATTTGTTACAGTATATTTATTACATCGACACACAGCAGTTGTCCATGGTGACCATAGCAAAACCTGCAGCAGTTGTCGGAAAAGATTTGACACTGCAGCTCAGTTATCGGCTCATGTCAAACAACAATGCTTATGTGATACATGCGCGGAAGTAGTATGTGGCGCTGCTGCCCTTCAACATCACCTTTTAAAACATAAGAAGAATACCGTTGAAATGGAAGAAGAAGAATGTTCATGA
Protein Sequence: MEAIMICRLCLKEVNEFKNAFAVTENKPTMASVIRIHFWFELQQNDPISTVICNNCWHKVSDFHDFYKSVEEAQSHLGENVTVKIENISAEHSIENVMIPSFSLSSKQEPEVNFDEVNDEVPFDMMTVETHSTRTDLRTDDPQDVWRNQNNNDNNAIEDVKDVIDYKDEVFNEHKSDPVNKPIFAENEESNKQTVNKKGISKTTKLSVKTQRNVPLAQKIHCKNVRAAKVPETEKNNVKKTKELSEQAKAIREQGLAFDGEIAKFMSLHCELCKLTATNFSSLHTHMLAEHKINGYVRCCNKKFSKRFALLDHIRHHSNPERFKCEQCNRVYANRNSMRTHFLSKHKNDKEKVFTCSQCPQKFFKKYLLRKHELFGHSDHKNACIAVDEEIANFMPLRCELCNEEATNFTALKGHMRDEHNIKGYVRCCNKKFCEHGLLVEHIRAHLNPACYKCEECSLVFPDRQSMRNHFLMEHGKMEDKPFACSLCSSKFVTVYLLHRHTAVVHGDHSKTCSSCRKRFDTAAQLSAHVKQQCLCDTCAEVVCGAAALQHHLLKHKKNTVEMEEEECS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -