Basic Information

Insect: Glossina austeni
Gene Symbol: esg
Assembly: GCA_000688735.1
Location: Scaffold14:262015-263954[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.7e-05 0.0013 19.2 3.5 1 23 313 335 313 335 0.99

2 6 3.8e-06 0.00029 21.2 3.3 1 23 390 412 390 412 0.97

3 6 1.9e-06 0.00014 22.2 0.7 1 23 425 447 425 447 0.98

4 6 3.7e-08 2.8e-06 27.6 0.4 1 23 451 473 451 473 0.97

5 6 4.2e-08 3.2e-06 27.4 2.1 1 23 479 501 479 501 0.98

6 6 0.00011 0.0082 16.7 0.4 1 21 507 527 507 528 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.7e-05	0.0013	19.2	3.5	1	23	313	335	313	335	0.99
2	6	3.8e-06	0.00029	21.2	3.3	1	23	390	412	390	412	0.97
3	6	1.9e-06	0.00014	22.2	0.7	1	23	425	447	425	447	0.98
4	6	3.7e-08	2.8e-06	27.6	0.4	1	23	451	473	451	473	0.97
5	6	4.2e-08	3.2e-06	27.4	2.1	1	23	479	501	479	501	0.98
6	6	0.00011	0.0082	16.7	0.4	1	21	507	527	507	528	0.95

Sequence Information

Coding Sequence: atggataaaataaatTATCGCAAATGTCCGCTAAAGAAGCGTCCTATATTACTGGTGGACACAGCTGCGGAAGTGAATACAAATCTTAAGGACCGACAAGACGAAGGTCCGGTGGATTTAAGTAAATCAGCTTATTCTCAAGTATCATCGACAAAAATCGACTCAAGTGCAGAAATACAAATTCAAGTTAATGCTCAATCCAAAGAGGAATTGGCCCGACGTATTTGGGAGGAGACGAGGGAAATTGCTAAAGCTTTCCCGGAGGTCTTTACGCGGGAAGAAATTGCACGTAGTTTAGCTCGCTTAGGTTATGGAGATTTCCCCTTACCACCGGAAAGACAACCAGGAGAAGCAGAAGAAGAACAGCAATTAGAAAGCTTTCCATCTATACGTTTACAAAACATCTCACCGACTCACATGAACTTGATACCTTCTCCTCATCCTCCTCTTTCTAACCTTCCAAGAGATGAAAATTTCTATAACGTTTCGATCAAAACTGAACCAAAGGATAGCGAAGTTATTGAGCCAGTTATGCGGAATTTTAATAATAATCTAATGAAAAGTATAGCCGAATATGAAGACTGTTTGCATGCCAGCAACTTTTCTAGAGAAACTTCCCCTCATGTGTTGGAAGGTAGTGAACCTTATAATCAAATAATGGATAACTATTCGGAACCTCAAGATTTAAGTGTAAAATCGTCGTCTGTCAACGTCTCGGGCGATGGTGGCAGCTTGCATCATGTAGCACGAGCACTTTTGGGTTTGCAAAATTTTCATCCCCATCAAGAAAGCGTTAACGAAATACAGCAGTACAATGACGGTAGCAGCAACAGCAATCATCATCGCAATAATATTTACAATGTTAAAGAAGTCTTGAAACCTTTAAGCAACAATACAAATTTGGGTTTAAAATTGAAAACCTCTAACGATTTGTATTATCAGTGTCAACAATGTAACAAATGCTATTCAACATATGCCGGTTTGGTGAAACATCAGCAGAGTCACGCTTTCGAGAGTACAGAATACAAAATAATACGCAGCAATCCGGAGGGTGGTAATGAAAGTTACGATTCTTCGGAATTTTCCACCGATCAAGCAGCTGCTCTTATACAAGCTTCAACGTTGGCTTCAACACAATCTATGCAAAAACCGGTAGGTGTGCCACGTTATCATTGCGATGATTGTGGCAAATCGTATTCAACTTTCTCAGGACTTAACAAACATCAGCAATTTCATTGCCCTGCGGCTGAGGGTAATCAAGTGAAAAAGATTTTTAACTGTAAAAATTGTGATAAAACTTATGTTTCGTTGGGTGCTTTGAAAATGCACATCAGAACTCATACTTTGCCCTGTAAGTGCCCTATATGTGGTAAAGCTTTCTCAAGACCCTGGCTACTGCAAGGTCATATACGAACGCACACTGGTGAGAAACCGTTCAGTTGCCAGCATTGTAATCGTGCTTTTGCCGATCGTTCTAATCTACGGGCTCATATGCAAACGCATTCGGATGTTAAGAAATATTCTTGTCCTTCATGTACTAAATCGTTTTCTCGCATGTCTTTGTTGGGCAAACACCTACAAAATGGTTGCCAATCCTCACCCAAGGAAGCTGCTGTTATGGAATCAGGTGGTCCCTTTAGTCAACATCTGCAGAACATGCCGCAGCATAGGCAAGATTTGCAAAATAGTTATTCTTCTCCTACGGATTATAATGAGAACATCAATCCCTCGCATCAACCGCGTATCTACTACGCAGACAGTGTATGCAGCAGTATAGGCGAAGAAGATGAGGATTACATGCATTCTACAACGACAAGAGTGACTCATCACTCTTCAATAAGACAAATGAACGAGTTTTGA
Protein Sequence: MDKINYRKCPLKKRPILLVDTAAEVNTNLKDRQDEGPVDLSKSAYSQVSSTKIDSSAEIQIQVNAQSKEELARRIWEETREIAKAFPEVFTREEIARSLARLGYGDFPLPPERQPGEAEEEQQLESFPSIRLQNISPTHMNLIPSPHPPLSNLPRDENFYNVSIKTEPKDSEVIEPVMRNFNNNLMKSIAEYEDCLHASNFSRETSPHVLEGSEPYNQIMDNYSEPQDLSVKSSSVNVSGDGGSLHHVARALLGLQNFHPHQESVNEIQQYNDGSSNSNHHRNNIYNVKEVLKPLSNNTNLGLKLKTSNDLYYQCQQCNKCYSTYAGLVKHQQSHAFESTEYKIIRSNPEGGNESYDSSEFSTDQAAALIQASTLASTQSMQKPVGVPRYHCDDCGKSYSTFSGLNKHQQFHCPAAEGNQVKKIFNCKNCDKTYVSLGALKMHIRTHTLPCKCPICGKAFSRPWLLQGHIRTHTGEKPFSCQHCNRAFADRSNLRAHMQTHSDVKKYSCPSCTKSFSRMSLLGKHLQNGCQSSPKEAAVMESGGPFSQHLQNMPQHRQDLQNSYSSPTDYNENINPSHQPRIYYADSVCSSIGEEDEDYMHSTTTRVTHHSSIRQMNEF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00747659;
90% Identity: iTF_00750668;
80% Identity: -