Basic Information

Insect: Gerris lacustris
Gene Symbol: hb
Assembly: GCA_951217055.1
Location: OX578277.1:33299206-33305250[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0037 0.62 12.2 1.1 2 23 197 218 196 218 0.96

2 8 0.031 5.2 9.3 0.2 2 23 221 243 220 243 0.95

3 8 0.023 3.9 9.7 0.5 1 23 273 295 273 295 0.98

4 8 0.0078 1.3 11.2 3.2 2 23 303 324 302 324 0.97

5 8 0.00015 0.025 16.6 4.7 1 23 330 352 330 352 0.99

6 8 0.055 9.1 8.6 5.2 1 23 358 382 358 382 0.93

7 8 0.0007 0.12 14.5 0.6 1 23 593 615 593 615 0.96

8 8 0.0093 1.6 11.0 0.4 1 22 621 642 621 645 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0037	0.62	12.2	1.1	2	23	197	218	196	218	0.96
2	8	0.031	5.2	9.3	0.2	2	23	221	243	220	243	0.95
3	8	0.023	3.9	9.7	0.5	1	23	273	295	273	295	0.98
4	8	0.0078	1.3	11.2	3.2	2	23	303	324	302	324	0.97
5	8	0.00015	0.025	16.6	4.7	1	23	330	352	330	352	0.99
6	8	0.055	9.1	8.6	5.2	1	23	358	382	358	382	0.93
7	8	0.0007	0.12	14.5	0.6	1	23	593	615	593	615	0.96
8	8	0.0093	1.6	11.0	0.4	1	22	621	642	621	645	0.90

Sequence Information

Coding Sequence: ATGAATACTGCGAAACTCGGATTATCTTGTACTATTGACCTAGaactatcacatagcttccgttaccgtcgGTGTTGTAATGCGATGATGGTGAGCGGAGAACTgtatagccaagacatgaactCGCTGGTACATCAGTATGACTCACTTCATTTCCAACAGCACTGGCCTCTTAATCATCAGCCCCTTCATTCTCTTATTAAGAAAGAACCGAGCGATGAATCCGATTATTTCAAGAAAGATAAAGTTCTTCCGTTGACTCCCCCCGGATATATGACAGATTATCAGCGTACCTCCGAATACGATAGTAGTGAATACTCCAACGGTGTCGACTACGGCGACGACAGAACAAGTTCGGACGAAAGGGAATGTCCGGACAAGGTGAGAACACCACCACTGTCGAGTCTCACTCCTGCTGTCACGCTTACAGAAGGTATGACGCCTCCAGGCTCCTCCCCGGACACGATGGGAGCTCTCGGCGAACACGCCTCGCCGGACAAGCACGAACAGATGTTCGAAAATGGAGACTCGcttaaaaaacttcaaatgGCCTTGCAAAGGAACGGACTTATTTACGAAGAGAAACTTCAATGTCCGATGTGCGACTTCAATTGCAGTGTTAGgtCTAGCTTCAACGAGCACCTTCTCTGGCACGAGACAAAATGTTCTGCTTGCGAATTCACTGGGGACACGAGAGACGCTTTGAAGGACCATATGAGGTTGGCACATGACGTGATGAGCGATGACGAACATTGGCCGGACGACGAACCAGGTCTCACCACCCCCAAAGTCAACTCGCAGGGTAAGGtgaaaacttttaagtgtaagcAGTGCGAGTTCTCGGCGGTAACTAAAGCTGAGTTCTGGGACCACTCTAAGGTGCACATCAAAAGGGATCGGATCCTCACATGCCCCAAGTGCCCTTTCATAACCGAGTACAAACACCATTTGGAGTACCACCTGCGTAACCACTTCGGATCTAAACCTTTCAAGTGCGACAAGTGCTCTTATACGTGCGTTAACAAGTCAATGCTCAACTCCCATCTTAAGAGTCACAGCAACGTCTACCAGTTTAGATGTGCAGACTGCACCTACGCAACTAAGTACTGTCACAGTTTGAAGCTTCATCTGAGGAAGTATGGACACGGCCCGGCCATGGTTCTTAATCCCGACGGATCTCCCAATCCACTTCCTATCGTGGACGTTTACGGTACCAGGAGAGGACCCAAACAGAAGGGAAGTGGCGGccccaataataataataacaacaacaacaataataataaggtttCCGAATCTCAGCAGACGTCCCCAAGCGTCCCCGTGTTCAATCCTTACAGCTTTATCCCTACACAGATTCCCTACTACAGCCTGCTCAACACCATACCTCCGTTCCCTTTTACTCCCGATCAAAACGAGGAGAAGAACAATAACGTGGAAAAGGCGACGGGAACGGAAGACGACGACGAAGAACCTCTCGAAGACAAGGCGCCTCTCGACCTCACCTGTCCTGAGCCGTCTAACGATTCCGACAACACCCAAAACAACTTCGACAATCCCGAGACACCCGTCACCAAGAACAGGAGAAAAGGAAAAGCCTACAAGATCGAAAAAGTGGCTTTGAGACTCACCAACGAAGGAGAAGACGACGACGAACCCGAACCTAAAAGACTCCGAGAAGAAGAATTGGTCGACCTCAGCCGAACCGCGAGATCGCCCGAAGTCAACCTCTGCGAAGCCGACAGCGAGCAGAAAGTCCTCGAGATAAAAGACGAATACAACTGCACGTACTGCGACATCTCTTTCAAAGACATCGTCATGTATACGATGCACATGGGCTACCACGGATACCAGGATCCTTTTACGTGCAACATGTGCGGACAGCAGACAGCCGACAAGGTCTCTTTCTTCCTCCACATCGCCCGCACATCTCACTCGTAA
Protein Sequence: MNTAKLGLSCTIDLELSHSFRYRRCCNAMMVSGELYSQDMNSLVHQYDSLHFQQHWPLNHQPLHSLIKKEPSDESDYFKKDKVLPLTPPGYMTDYQRTSEYDSSEYSNGVDYGDDRTSSDERECPDKVRTPPLSSLTPAVTLTEGMTPPGSSPDTMGALGEHASPDKHEQMFENGDSLKKLQMALQRNGLIYEEKLQCPMCDFNCSVRSSFNEHLLWHETKCSACEFTGDTRDALKDHMRLAHDVMSDDEHWPDDEPGLTTPKVNSQGKVKTFKCKQCEFSAVTKAEFWDHSKVHIKRDRILTCPKCPFITEYKHHLEYHLRNHFGSKPFKCDKCSYTCVNKSMLNSHLKSHSNVYQFRCADCTYATKYCHSLKLHLRKYGHGPAMVLNPDGSPNPLPIVDVYGTRRGPKQKGSGGPNNNNNNNNNNNKVSESQQTSPSVPVFNPYSFIPTQIPYYSLLNTIPPFPFTPDQNEEKNNNVEKATGTEDDDEEPLEDKAPLDLTCPEPSNDSDNTQNNFDNPETPVTKNRRKGKAYKIEKVALRLTNEGEDDDEPEPKRLREEELVDLSRTARSPEVNLCEADSEQKVLEIKDEYNCTYCDISFKDIVMYTMHMGYHGYQDPFTCNMCGQQTADKVSFFLHIARTSHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00743149;
90% Identity: iTF_00743149;
80% Identity: -