Basic Information

Insect: Gerris buenoi
Gene Symbol: mecom-a
Assembly: GCA_001010745.2
Location: KZ653048.1:46396-51970[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.071 9.6 8.4 0.1 2 23 25 47 25 47 0.94

2 9 1.4 1.9e+02 4.3 1.2 1 23 54 77 54 77 0.92

3 9 5.6e-09 7.7e-07 30.8 0.4 1 23 84 107 84 107 0.98

4 9 6.4e-06 0.00088 21.1 2.6 1 23 113 135 113 135 0.95

5 9 3.4e-05 0.0046 18.9 4.8 1 23 141 163 141 163 0.99

6 9 0.00045 0.061 15.4 1.1 2 21 171 190 170 191 0.95

7 9 1.3e-08 1.8e-06 29.6 0.7 1 23 576 598 576 598 0.98

8 9 5e-08 6.8e-06 27.8 0.8 1 23 604 627 604 627 0.98

9 9 7.5e-06 0.001 20.9 4.3 1 23 633 655 633 655 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.071	9.6	8.4	0.1	2	23	25	47	25	47	0.94
2	9	1.4	1.9e+02	4.3	1.2	1	23	54	77	54	77	0.92
3	9	5.6e-09	7.7e-07	30.8	0.4	1	23	84	107	84	107	0.98
4	9	6.4e-06	0.00088	21.1	2.6	1	23	113	135	113	135	0.95
5	9	3.4e-05	0.0046	18.9	4.8	1	23	141	163	141	163	0.99
6	9	0.00045	0.061	15.4	1.1	2	21	171	190	170	191	0.95
7	9	1.3e-08	1.8e-06	29.6	0.7	1	23	576	598	576	598	0.98
8	9	5e-08	6.8e-06	27.8	0.8	1	23	604	627	604	627	0.98
9	9	7.5e-06	0.001	20.9	4.3	1	23	633	655	633	655	0.99

Sequence Information

Coding Sequence: ATGGTCACgagaattattaatagAGGATCTCAGAATTCTGGTGAAGATAAAGAGGACGAAGAGGATTACCCGAGGTGTCCTGCTTGCGATACACCGTTCCAAGATTCTGACTTgttggaCGAACACTTAGTGAAAAAGCACAGATACGAAAGCGGTCAACACCGTTGCGAAGCTTGCGGACGTGGTTATGCTTGGAGGCCGTGCCTTACTCGTCATAGATCACTAGCCCACGGTGCTCCGTCCAGGAGATACCCTTGTGAGAACTGTCCTAAGACCTTTTCGGACCCTTCTAACCTACAACGACATATCAGGTCTCGTCACGCTGGAGCTAGATCCCACGCCTGCACCGAGTGTGGTAAAACGTTCGCCACCTCATCAGGATTGAAACAACACACGCACATTCACTCGAGCGTCAAGCCCTTCCAGTGCGAGGTCTGCTACAAGgctTATACGCAATTTAGTAACCTGTGCCGCCACAAACGGATGCACGTCTCTTGCCGTATGCAAAGCAAGTGCAACAAGTGTGGACAAACCTTCAGTACAGGCACTTCATTGGCTAAACACAAGAGATTCTGCGACTCGAGCAGCGGAGTCAACATGAACAGTCTTCCACCAGGTGGATCAAGCCCATTCCTGCTCTACCCACCCAGGCCAGGTCTTCCCTTCTACCCTCCTGGTCTTGTACCACCATACTCCGGCCTCTTCCACAGCCCTACAGCACCTCCTCCAGGATTTCTTCCTAACTCCCTTCTCTTCGCTCCTCACCACAAGTCCTCCGAAGACGAATCCATGAGCAGTAGTGCCAAGATGTCGTCGATGCAGAGAATGAGAACGGAAAGTAATTCCACCTGCAGTCCTATTGGATCACCAGGAGAAAGTCCGTCGCCAATGCACGATTCTTCTTCTACTCCAAATAATTCATTCCAACTGATGAATAAAGTTTCCCCACCGACTGCAGAAGAAGCGGCGTCGAGCGAAAGACCTTCACCTGCGCGTCCACCGATGTCTGCGACCTATCCTAATCCTAAAGTTAACATACCTTCGTTCGCCGAATCAAATGAAGAGCAAACTCCTGTCTCGTCGAAAAGGCCTTATAAATGTGAATCTTCAGATCAACCTCTGGATCTTTCTGTATCCAAGAAAGACGAGCAACGCTGTGATTCGCCGCACAAGGGCGCTAAACGAAGTCGTCTATCTTCTCCAGTCCACTCCGATTACAGTGAGAAATCTGACGAAGACATAGAACCCGACTCTCCGGTTAAAGTATCGACACCCGAACCAGTAAGAGATGCTTCCCCACTCCCCCTGACGCCTAAGAAAGAAGTCGAAGTGGAATCTACTACGGAGGAGAGCCCTAACAACCAACCCGAATCACTATCTCTTAAACCTTTTAGTGATTTAAAAGAAACCATCGAGAAGACAGACAACGAAAATAACAACAGAATGCCGATGGCTTATCCAAGGCCGATACATCCTCTTTTCCTCGAAGCACTCTACAGGCCTCCCTTTCCTAACTTTGGACGTGACGCAACGGGTGTCGCCGATCAGGTATTTAATCAGAATCCTTTCGGCGTTCGTCCTGCATTCCCGTTCTTGGGACATTTGATGAACGGAATGGCTAGACAAAACAGATCTTTCGAAATGATGAGACCACCGATGCCTTCTTACCCCACCAAGACGTTCTCAGAAGGTATGACACCTAACGGACAGAAAATGAAAGACAGATATGCGTGTAAATTTTGTGGAAAAGTGTTCCCCAGGTCCGCTAATTTAACCAGACATCTCAGGACTCACACCGGAGAGCAACCTTACAAGTGTCCTTACTGCGAGCGATCTTTCAGCATATCGTCAAACCTCCAGCGTCACATAAGAAACATCCATAACAAAGAGAAACCTTTCAAATGTTCCATGTGTGACAGATGTTTCGGTCAACAGACAAACCTTGACCGACACATCAAGAAGCATTCTTCCGAAGACGGTATCATCTCTGTCGAAGATTCACCTGATAACAGTAACGAAAACGAACGAGAAGATGCTTATTTCGACGAGATACGTAGCTTCATGGGTAAAGTGACTTACGCAGGAGGACCGGAGCAGATCTATACTCCTACCTCGCTCTATCACCCCGCTTTGTCTTCGTCCAAAGATGACGACGAATCATCAGATACTTCTTTATCACCTAGCTATCACAAACAAGAACTTCCTCTTGCAATGGTTATTCCTAAACACCTTTCCGCTTCCTGCAAAGACGAACCGCTTCTCAACAACAACGACCAGCAAGAACCTCTTCATATTTCTACTTAG
Protein Sequence: MVTRIINRGSQNSGEDKEDEEDYPRCPACDTPFQDSDLLDEHLVKKHRYESGQHRCEACGRGYAWRPCLTRHRSLAHGAPSRRYPCENCPKTFSDPSNLQRHIRSRHAGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCYKAYTQFSNLCRHKRMHVSCRMQSKCNKCGQTFSTGTSLAKHKRFCDSSSGVNMNSLPPGGSSPFLLYPPRPGLPFYPPGLVPPYSGLFHSPTAPPPGFLPNSLLFAPHHKSSEDESMSSSAKMSSMQRMRTESNSTCSPIGSPGESPSPMHDSSSTPNNSFQLMNKVSPPTAEEAASSERPSPARPPMSATYPNPKVNIPSFAESNEEQTPVSSKRPYKCESSDQPLDLSVSKKDEQRCDSPHKGAKRSRLSSPVHSDYSEKSDEDIEPDSPVKVSTPEPVRDASPLPLTPKKEVEVESTTEESPNNQPESLSLKPFSDLKETIEKTDNENNNRMPMAYPRPIHPLFLEALYRPPFPNFGRDATGVADQVFNQNPFGVRPAFPFLGHLMNGMARQNRSFEMMRPPMPSYPTKTFSEGMTPNGQKMKDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCPYCERSFSISSNLQRHIRNIHNKEKPFKCSMCDRCFGQQTNLDRHIKKHSSEDGIISVEDSPDNSNENEREDAYFDEIRSFMGKVTYAGGPEQIYTPTSLYHPALSSSKDDDESSDTSLSPSYHKQELPLAMVIPKHLSASCKDEPLLNNNDQQEPLHIST*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01009728;
90% Identity: iTF_00743966;
80% Identity: -