Basic Information

Gene Symbol
-
Assembly
GCA_959613385.1
Location
OY390740.1:3966639-3967688[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 7.1e-05 0.005 18.2 4.7 1 23 57 79 57 79 0.98
2 9 3.2e-06 0.00022 22.5 4.0 1 23 85 107 85 107 0.98
3 9 1.3e-05 0.00094 20.5 4.1 1 23 113 135 113 135 0.99
4 9 2.1e-06 0.00015 23.0 1.7 1 23 141 163 141 163 0.97
5 9 3.3e-06 0.00023 22.5 6.1 1 23 169 191 169 191 0.99
6 9 0.00011 0.0077 17.6 6.0 1 23 197 219 197 219 0.99
7 9 1.4e-05 0.00098 20.5 6.0 1 23 225 247 225 247 0.99
8 9 2.5e-06 0.00018 22.8 2.6 1 23 253 275 253 275 0.99
9 9 0.00054 0.038 15.5 0.3 2 23 282 303 281 303 0.98

Sequence Information

Coding Sequence
ATGAAGGAAGAAAATGACGATGCTTCTGTGCAGGTGACATCAAGGACTTTTGATCCTGTTAGTATACCACAAGCTGTTTCAAGCGCTGAATTTACACCTGATATCAAAATTAACTTGGGTGTTGCAAATTGCAATAGCAACGTCAAAATACGTGCGATCGAAAGAAaccataaatgtgaaatttgcaataaacgcTTCGCCGCAAAGCAACACCTATCGAGACACGTCAAATCGCACACGGGCGAGCGAAATTTCAGATGCgagatttgcaacaaatgcttcacaacgaaACAAAACATGTCCGAGCACATGAAAGgacacaccggcgaaagaaactATCAGTGCAAAATCTGCAGCAAGTGCTTCGCGACCAAACAGAACGTGTCGACGCATGTCAAGACGCACACCGGAGAGCGAAACTTTAAGTGCGACATCTGCGACAAACGCTTCACCACGAAACGCAACATGCTGCAGCACGTGAAGGCGCACGCCGGCGAGCGaaactacaaatgcgaaatttgcgacaaatgctGCGCGACGAAGCAGAACCTATCGAAGCACATCAAGAGGCACGCGGGCGAGCGAAATTACAGGTGCGAAATTTGCTACAAGTGCTTCACGACGTACTACTACATGTTGAAGCACGTGAAGACGCACACGGACGAGGGGAACTATAAGTGTGAGGTTTGCAACAAGTGCTGCGCGACGAAACAGAATCTGCTGAAACACGTCAAGACGCACACCgggaagaagaaatttaaatgtgaaatttgtggCAAGTACTTCACGACGAAGTATTATATGTTGCAACACGTGAAAACGCACGACGTCGAAAGGGGcaataaatgcgaaatttgcagtCTGGGTTTCCGAGAAAGTGACGTGTTGTTCGACCACATGAAAACGCACGCTGAGCAAAATGGCAAGGGACAGGttctacaaaattttaaaatggaagaaattagCAACATTGATGAACAGTTTATTAAGGAGGAGTTTAGAACATTCCGAGAGAGAGACTTTTTGGAGACCGATGGTAAGAATTTTTAG
Protein Sequence
MKEENDDASVQVTSRTFDPVSIPQAVSSAEFTPDIKINLGVANCNSNVKIRAIERNHKCEICNKRFAAKQHLSRHVKSHTGERNFRCEICNKCFTTKQNMSEHMKGHTGERNYQCKICSKCFATKQNVSTHVKTHTGERNFKCDICDKRFTTKRNMLQHVKAHAGERNYKCEICDKCCATKQNLSKHIKRHAGERNYRCEICYKCFTTYYYMLKHVKTHTDEGNYKCEVCNKCCATKQNLLKHVKTHTGKKKFKCEICGKYFTTKYYMLQHVKTHDVERGNKCEICSLGFRESDVLFDHMKTHAEQNGKGQVLQNFKMEEISNIDEQFIKEEFRTFRERDFLETDGKNF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-