Basic Information

Gene Symbol
-
Assembly
GCA_959613385.1
Location
OY390740.1:1727881-1729041[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 8.1e-07 5.7e-05 24.4 1.9 1 23 109 131 109 131 0.99
2 10 3.9e-06 0.00027 22.2 3.1 1 20 137 156 137 158 0.95
3 10 0.042 2.9 9.5 2.3 2 23 164 184 163 184 0.89
4 10 3.5e-06 0.00024 22.4 2.3 1 23 190 212 190 212 0.99
5 10 2.3e-06 0.00016 22.9 5.6 1 23 218 240 218 240 0.98
6 10 9.2e-07 6.5e-05 24.2 4.8 1 23 246 268 246 268 0.98
7 10 0.81 57 5.5 4.1 1 15 274 288 274 296 0.70
8 10 1.5e-07 1.1e-05 26.6 2.0 1 23 303 325 303 325 0.98
9 10 6.5e-06 0.00046 21.5 1.6 1 23 331 353 331 353 0.95
10 10 0.0003 0.021 16.3 5.7 1 23 359 381 359 381 0.98

Sequence Information

Coding Sequence
ATGGAGGAGATTGACGTGAAAGATTTCAACTCGATTGTCGAAGTAAAATCTGAGCCGGTAGAATGTACGACTTTCTTCTCAAAACTGGGGCCTTTATATTCTCCTACTGACGATGACcggaaaaaaatggaatttgtaAAGGAAGACAAATACGAGAAATATGCTGGAATTGCAGCCGATGACATCAGAATTAAGTTGGACCTCGGCGACGACGACGATCAGTTGAATTCCGAAACGAGAAAATTCGCATTGGAGGAAATCAATTTACGAGCCGAAGAAAAAAGTCAAGGTGAGCTCGGAGATTTTATGCGCAATGaaggaaactacaaatgcgacATTTGCACCAAATCGTTCTCGACGGAGGAATTTCTTCGGCGACACGCGAAAACGCACATTACGAAAATTTATTacgaatgtaaaatttgcaacaagtgCTTCAGAACAAAACAACATTTAGCGCGACACGTCGACAGCGGAGACAGGAAtgacaaatgtgaagtttgcggCAAATACTACAGCAGAAAGTGTTTTTTAGCGCACGTCAAAATGCACACGGGAGAAAAACgttacaagtgcgaaatttgcagcaaatcCTTCGCATCGAAACACTACCTACTGGTGCACGTCAAATCGCACACcgcaaaaagaaatcacaaatgcgaagtttgcgACAAACGCTTCAGAACGAAAGAACATTTAACGCTGCACGTCAAAACGCACAACAGAGAAAGAAATCACGAATGCGAAGTTTGCGACAAACGCTTCAGAACGAAACAACATTTGGCGAAACACGTCAGAACGCACACCGtagaaagaaatcacaaatgtgaagtttgcaataaatcctTCTTATCGAAGCACTACGCGTCGTTCCATCTCAAATCGCACTTCGgagaagaaagaaatttcaaatgtgaagtttgcgacaaGCGTTTCACAACGAGGCAGAATTTAAAACGACACGCCGAAACGCACGGCGGAGGAAGGAatcacaaatgcgaaatttgcgacaaatcCTTCTCGACGAAATTCTATCTGTCGGTACACGTCGAAGGGCACGCCggagttaaaaattacaaatgcgaaatttgtaaCAAGTGTTTCACCTCGAAAAAATGTATATCGGTACACGTCAAAATACACATGAAAGAGAGAAATTGA
Protein Sequence
MEEIDVKDFNSIVEVKSEPVECTTFFSKLGPLYSPTDDDRKKMEFVKEDKYEKYAGIAADDIRIKLDLGDDDDQLNSETRKFALEEINLRAEEKSQGELGDFMRNEGNYKCDICTKSFSTEEFLRRHAKTHITKIYYECKICNKCFRTKQHLARHVDSGDRNDKCEVCGKYYSRKCFLAHVKMHTGEKRYKCEICSKSFASKHYLLVHVKSHTAKRNHKCEVCDKRFRTKEHLTLHVKTHNRERNHECEVCDKRFRTKQHLAKHVRTHTVERNHKCEVCNKSFLSKHYASFHLKSHFGEERNFKCEVCDKRFTTRQNLKRHAETHGGGRNHKCEICDKSFSTKFYLSVHVEGHAGVKNYKCEICNKCFTSKKCISVHVKIHMKERN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-