Basic Information

Insect: Geotrupes spiniger
Gene Symbol: nesd
Assembly: GCA_959613385.1
Location: OY390740.1:12917098-12924750[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0035 0.25 12.9 1.4 1 23 665 687 665 687 0.98

2 14 0.00039 0.028 15.9 2.7 1 23 693 715 693 715 0.99

3 14 0.00043 0.031 15.8 4.2 1 23 721 743 721 743 0.98

4 14 4.7e-05 0.0033 18.8 6.7 1 23 749 771 749 771 0.98

5 14 6.6e-05 0.0047 18.3 0.8 1 23 777 799 777 799 0.98

6 14 0.00017 0.012 17.1 1.9 1 23 805 827 805 827 0.99

7 14 0.0003 0.021 16.3 7.5 2 23 834 855 833 855 0.97

8 14 2e-05 0.0014 20.0 2.2 1 23 860 882 860 882 0.99

9 14 8.9e-05 0.0063 17.9 1.3 1 23 888 910 888 910 0.98

10 14 0.00062 0.044 15.3 7.7 1 23 916 938 916 938 0.98

11 14 0.00021 0.015 16.8 6.2 1 23 944 966 944 966 0.98

12 14 2.9e-05 0.0021 19.5 1.9 1 23 972 994 972 994 0.98

13 14 2.1e-05 0.0015 19.9 5.9 1 23 1000 1022 1000 1022 0.98

14 14 3 2.2e+02 3.7 0.6 7 23 1034 1050 1028 1050 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0035	0.25	12.9	1.4	1	23	665	687	665	687	0.98
2	14	0.00039	0.028	15.9	2.7	1	23	693	715	693	715	0.99
3	14	0.00043	0.031	15.8	4.2	1	23	721	743	721	743	0.98
4	14	4.7e-05	0.0033	18.8	6.7	1	23	749	771	749	771	0.98
5	14	6.6e-05	0.0047	18.3	0.8	1	23	777	799	777	799	0.98
6	14	0.00017	0.012	17.1	1.9	1	23	805	827	805	827	0.99
7	14	0.0003	0.021	16.3	7.5	2	23	834	855	833	855	0.97
8	14	2e-05	0.0014	20.0	2.2	1	23	860	882	860	882	0.99
9	14	8.9e-05	0.0063	17.9	1.3	1	23	888	910	888	910	0.98
10	14	0.00062	0.044	15.3	7.7	1	23	916	938	916	938	0.98
11	14	0.00021	0.015	16.8	6.2	1	23	944	966	944	966	0.98
12	14	2.9e-05	0.0021	19.5	1.9	1	23	972	994	972	994	0.98
13	14	2.1e-05	0.0015	19.9	5.9	1	23	1000	1022	1000	1022	0.98
14	14	3	2.2e+02	3.7	0.6	7	23	1034	1050	1028	1050	0.83

Sequence Information

Coding Sequence: atggacgAAGTAATTCTCTTCGATAAAAGTTTAATGGAAAGACTTCAAGAATATCTGGAAGTCTTATCTGGCTACGAGGCGCTACCCGTTTCGCACATCAAAGGCGAATGGTCTTTTTACCTAGAATTGACCATGGATCCAAATGGATGGCAAGCGGTTTGGAAAATACCACGCCTAACTTGCGAATTGTATAAAATACCATTTCCAACTATTGTGCTGGTGTACGTCGAGAATGTCGATTTTAAACCACTAGCGGCTACTGTTAAAATTTTGGCCGTTCAAGATGATATATCGTTGCCCGATAAACACGTCGTGCCTTTAATTCAACTGTGGCCCACGAGGGAACAAGATAAATCAATCGTGTTAAGCATACAATCAACTGCCAATGCTTTAGATATGTTAAGATTCTTTTATAATAATCTTGTGCTGCCGTGGGATTATGAGGATGATGATACATCAGACTGGTTAAACAAACATTTAGAATCTCGCTTGAGACTATTTTATGACATGAAAAATGGAACGATACCTAAGCCAGTGGCCGAACATCTTCGTAGCTTACTTACGGAAGCTAGACGCTTGCATTCACGAAAGGAACAACTGGAAAAAGCGCTGGGTGACGAtgatgattttgatttaaacgATGCTACTACTGACGACGAGCAATTGCAAAGTTTAATCGATTTACATGTACGTATTGTACAAATACGTGGAGAAGTCGAAATCTTAGAGAATCCTTTAATGCGCAACGTAATATTAAAGCGTCAACAAGAATTGATGTCCACAACAGAAAGCTCAACACCTTCGCATTTCCTAGTCTTCGATGAGGGTAAAGTAGATGAATACATAGCCTTTTTAAATCAGGTGAAAAATCGGTATCCTAATGAActtgttaaatttgtttcaaatctgGCGTCTGCGATTGAAATTGCCAATTGCAACGACTTTATTATTCTCACCAACACAAATTATGCTTTAAAGACAACCGCCCGGCTTGAGAGCGGAGGCATCATTAAAGGAATAACTGATACTAACGAGGCTGTAATTTCATCAACAAACGAAGAAGTTATGTTCGATTTTAGCGGCAACGTCACTTTGGAAAACGTTACCGTAAACGCAGGTTTGTCGCAATGCGGGATCGTCGTAAGACACGGTGATGTCACCATGACCAATTGCAAAATAATCGGTGACGGAAAATCATCGACTCATCAAGGAATAATCGTACTAGCCGGGAGTAATTTAAATCTCGTCGATTGTGACATTAGCAATTTTTGTACGGCCTTGGTTGGTAATTCGGGTTCGAAAATAACCATGAAAAATTGCGTGATACACGAAGTTAATTACGGCGTGAAGGTTTTCGATCAGTGCGTTTTTTCCGCGCAAACTTCTAATTTCCGCGATTGTCGCGAGTACGGAGTTTGCGTGGAAACGGACAGCATTTCGCACggcgaaataaaaatcggaaaTTTCGACGTTCTGCAAATcGTACCTCACGTTACGATTTGCGACGTTAATGGCGATGGTAATGGAAAAGGTGACGTCAAAATAAATCAGAAACCAAGAATTCAACCGATCAAGAATATTTTCCCCGTTGAATCGGCGACTTGTAAAAAAGAATTGTCGTCGGACGAAGAAATGGACGTACCCGTCGATGACTTGGAACGCATAATGGAGACTGATGTAAGTGATTACAATAGCCCTCTGATCGAAGTGAAGCCTGAATCAATAGAACGtccacatttttacaaatattctcATGTTAAAATTGACGATGAATGTATCATAAAAGAAGAGGAATATGACGATGCAAATGCAGAAAATCTTGATGATATTGCACGTAACAACATCAAAATTGACCCGGATCTCGTTGATGACAATGACTTATTGAACTTTTGCGTCAATAAGGACCGAAAGAAACAAGCTAATGCTGAAACTGGCATTGAAACAACAATTGACTTATTCGTCAAAAATTCCAAGATATGTCCAAATGAAAGATACGAGTGTGAAGTTTGCTCCGGGCATTTCAAAACAAGAGAAGGTATGTTGAAACACATGAAATTGCACACCGACGCgaaaaactacaaatgtgaaatttgcaacaaacacTTTGCGGCGAAGCGCTACTTGTTCGAGCACGCCAAAACACACGACAAACAAACACGCTACAAATGCGAAACTTGCGTCAAATGCTTCACAATGAAACGAAATTTATCGAAACACGTCGAGAGCCACGCCGGAGAAAGAAAtcacaagtgtgaaatttgcagcaaatgctTCACGACTAAGCAAAATCTGTCGCGGCACGCCCAGAGGCACGCCGACGAAAAACGCTACAAATGCAACATTTGTGACAAACGCTTCGTAACAAACCAAGTTATGTTGCGGCACGTGAAAATACACAGAGGCGAacgaaactacaaatgtgaaacttGCGATAAGGGCTTCGTAACGAAACAATACATGCTGCAGCACACGAAGATGCACGCGGGCGAGAGaaacaacaaatgcaaaatttgcggTAAGTGCTTCTCGACGAAACAGTGTCTTTTGAAACATACCGAAAGACACACCGAAAGAATCTACAAATGTGAGATTTGCAAGAAAGGCTTCAAAACTAAAGAATATATGTTGAAACACGTGAAAATGCATGACGACCGTCAGAGatataaatgcgaaatttgcaatgTTTGCTTCACGACTAGTCAAAGCGCGTTGCGGCACATGATAGTACACACCGGCGAAAAAAACCACAGATGTGACATTTGCAGTAAATGCTTCACTAGGAAACAGTACTTGCTGCAACATCGTACAACGCATATCGGCAGCAAAAACCATAAATGTGACACATGTAATAAACGCTTCACtacgaaacaatatttgtttcaacACGCGAAAACGCACATCGGTGGGAAATGCTACGAATGTGACATCTGCAACAAATCTTTCACGACGAAACGGTACATGTCGCAACACGTGAAACTGCACATCGGAGAACAAAACCATAAATGCAAGATTTGCGGCAAATGCTTCACGACGAAACAAAACATGTTACAACATGTCAAAGTGCACGCTGATAAACGGAACTACAAATGCAAAATCAGCGAAAAATGCTTCACGACAGGTGAAACTGTGTCGCGGCACATGTCGGTGCACATTCGAAATTTGTCATGTGTCCTTCCAACGattaaaacagaagaaattaatgAGGTCGATAAATCGATGATTAAGGCAGAGATTGATGAAAGTAAGGAAGATGAGCACAAACCAACGGAAATTGTAGATCTATGTTCAATGCTCcacaatgaaattataatcaaGGAGGAGCATGTAATGGATACcacataa
Protein Sequence: MDEVILFDKSLMERLQEYLEVLSGYEALPVSHIKGEWSFYLELTMDPNGWQAVWKIPRLTCELYKIPFPTIVLVYVENVDFKPLAATVKILAVQDDISLPDKHVVPLIQLWPTREQDKSIVLSIQSTANALDMLRFFYNNLVLPWDYEDDDTSDWLNKHLESRLRLFYDMKNGTIPKPVAEHLRSLLTEARRLHSRKEQLEKALGDDDDFDLNDATTDDEQLQSLIDLHVRIVQIRGEVEILENPLMRNVILKRQQELMSTTESSTPSHFLVFDEGKVDEYIAFLNQVKNRYPNELVKFVSNLASAIEIANCNDFIILTNTNYALKTTARLESGGIIKGITDTNEAVISSTNEEVMFDFSGNVTLENVTVNAGLSQCGIVVRHGDVTMTNCKIIGDGKSSTHQGIIVLAGSNLNLVDCDISNFCTALVGNSGSKITMKNCVIHEVNYGVKVFDQCVFSAQTSNFRDCREYGVCVETDSISHGEIKIGNFDVLQIVPHVTICDVNGDGNGKGDVKINQKPRIQPIKNIFPVESATCKKELSSDEEMDVPVDDLERIMETDVSDYNSPLIEVKPESIERPHFYKYSHVKIDDECIIKEEEYDDANAENLDDIARNNIKIDPDLVDDNDLLNFCVNKDRKKQANAETGIETTIDLFVKNSKICPNERYECEVCSGHFKTREGMLKHMKLHTDAKNYKCEICNKHFAAKRYLFEHAKTHDKQTRYKCETCVKCFTMKRNLSKHVESHAGERNHKCEICSKCFTTKQNLSRHAQRHADEKRYKCNICDKRFVTNQVMLRHVKIHRGERNYKCETCDKGFVTKQYMLQHTKMHAGERNNKCKICGKCFSTKQCLLKHTERHTERIYKCEICKKGFKTKEYMLKHVKMHDDRQRYKCEICNVCFTTSQSALRHMIVHTGEKNHRCDICSKCFTRKQYLLQHRTTHIGSKNHKCDTCNKRFTTKQYLFQHAKTHIGGKCYECDICNKSFTTKRYMSQHVKLHIGEQNHKCKICGKCFTTKQNMLQHVKVHADKRNYKCKISEKCFTTGETVSRHMSVHIRNLSCVLPTIKTEEINEVDKSMIKAEIDESKEDEHKPTEIVDLCSMLHNEIIIKEEHVMDTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -