Basic Information

Gene Symbol
-
Assembly
GCA_959613385.1
Location
OY390740.1:482846-484552[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.49 35 6.2 0.8 7 23 102 118 102 118 0.95
2 13 0.013 0.89 11.2 1.8 2 23 125 146 124 146 0.97
3 13 1.9e-05 0.0013 20.0 3.5 1 23 152 174 152 174 0.98
4 13 0.04 2.8 9.6 0.3 1 23 180 202 180 202 0.96
5 13 0.00092 0.065 14.7 2.3 1 23 208 230 208 230 0.97
6 13 4e-06 0.00028 22.2 3.0 1 23 236 258 236 258 0.98
7 13 5.5e-05 0.0039 18.6 0.6 1 23 264 286 264 286 0.99
8 13 1.7e-06 0.00012 23.3 3.0 1 23 292 314 292 314 0.98
9 13 3.2e-05 0.0023 19.3 5.4 1 23 320 342 320 342 0.99
10 13 2.6e-07 1.9e-05 25.9 2.8 1 23 348 370 348 370 0.99
11 13 2.9e-06 0.00021 22.6 2.1 1 23 376 398 376 398 0.99
12 13 3.1e-06 0.00022 22.5 1.2 1 23 404 426 404 426 0.98
13 13 0.53 37 6.1 0.1 5 23 436 454 435 454 0.94

Sequence Information

Coding Sequence
ATGGAAACGATTAATTCCAACTTCACCGTCGCCGACGTGAAACTCGAACCGATGGAATTTACTCCCTTAACTCCAAAATCGGAGACTTGTGTTGGTTATCGTCGAGATGTTGATATCGACCACGTCTACGTCGAAGATGCTATTGCAATAAAGGAAGAGAATTATGTTGAGGAGGCATCTGTGCCAACGACGGATGTGCAATGTAACGCAATCGATATTTCCAGTGCAGCTCAAAATGACGTCGAAGTTAAATTGGATGTCGGTGATGATTCGATTAAGTCTTTGGGTAGCGACGAGATGTTTCACAAACGTTTCGTAACTGAATCGTGTTTGTCGCGACACGCGAAAGTGCACAGCGGGgaagaaaacaacaaatgcgaGATATGCGCAAAATGCTTTTCGATGAAGTCGATTCTATTGACGCATTTAAAAGCGCACGCCGGCGAGAAAAACCACGAATGTCAACTATGCGACAAGCGATTCGCATCGAAAACATATTTGTCGAACCATTTGAGAAGACACGCCGGCGAGAAAAACCAcgagtgcgaaatttgcgcgaAACGTTTCGCCGCCAAAAGGAGCGCGATCAACCACGCGAAAATTCACGCCGGCGAGAGGAACCACGAGTGCGAGTTTTGCGCGAAACGCTTCACCAGAAAACGAAACATGTTGGTCCACGCGAAGATCCACGCCGGCAGTGAAAGCCACAGGTGCGAAATTTGCGGTAAATCGTTcgcgacgacgacgaatctctcgCACCACGTGAAaatacacaccggtgaaagGAACTACGAGTGCGGGATTTGCGCGAAGCGTTTCACGAGGAAGGGGTACATGTCGATCCACGTGAAGACGCACTCGGGCGACAAGAaccacaaatgcgaaatttgcgccaAGCGATTTACGACGAAGGAAAATTTATTGAGACACGTGAAGACGCACACCGACGAAAAAAACTACAGGTGCAAGATCTGTTCGAAATGTTTCACGACGAGAGTTTACATGCTCAGACATGTGAAAACGCACGCggacgaaaaaaattacaaatgcggaATTTGCACCAAGTGTTTTACGGAGAAGGGTAATTTGTCGATCCACATGAGAACCCACACCGGCGAAAGGAATTATAAATGCGACGTTTGCTCGAAACGTTTCACGAGAAAAGGAGACATGACGGTCCACACGAagacgcacaccggcgaaaaaaattacgaatgcgaaatttgcgacaaacgATTCACGACGAAAGACGATCGATCGAGACATGTGAAAATGCACGAGGGGGAGACGAACTATAAGCGTGAAGTGTGCGACGATTCCTTCACGACGAGAGAAAATACGTTGGAACATATTAAGTTACACGTCGACGAAAATTACGAACAAGTGCACGATGAAGTAAAAGTTTCCTTTGGAAAACTGTCGCCTGTGAAAGAAGAAAACGGTGCAATTATAAATCCGGAGATTGAGCAAGAAGTCCTTgtgtttgtaaaaaatgaaaaattggaaattgtcGACGACGTTGTTGAAAAAGAATCGTCAGCGGCTACAAATCGCGATGTTGTCGATGGTGTCGTGGAAGAGAGACCCGAATCAAaagaaattttcgatttatga
Protein Sequence
METINSNFTVADVKLEPMEFTPLTPKSETCVGYRRDVDIDHVYVEDAIAIKEENYVEEASVPTTDVQCNAIDISSAAQNDVEVKLDVGDDSIKSLGSDEMFHKRFVTESCLSRHAKVHSGEENNKCEICAKCFSMKSILLTHLKAHAGEKNHECQLCDKRFASKTYLSNHLRRHAGEKNHECEICAKRFAAKRSAINHAKIHAGERNHECEFCAKRFTRKRNMLVHAKIHAGSESHRCEICGKSFATTTNLSHHVKIHTGERNYECGICAKRFTRKGYMSIHVKTHSGDKNHKCEICAKRFTTKENLLRHVKTHTDEKNYRCKICSKCFTTRVYMLRHVKTHADEKNYKCGICTKCFTEKGNLSIHMRTHTGERNYKCDVCSKRFTRKGDMTVHTKTHTGEKNYECEICDKRFTTKDDRSRHVKMHEGETNYKREVCDDSFTTRENTLEHIKLHVDENYEQVHDEVKVSFGKLSPVKEENGAIINPEIEQEVLVFVKNEKLEIVDDVVEKESSAATNRDVVDGVVEERPESKEIFDL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-