Basic Information

Insect: Geotrupes spiniger
Gene Symbol: ETV5
Assembly: GCA_959613385.1
Location: OY390734.1:11588869-11592898[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00037 0.026 16.0 1.3 2 22 350 370 349 370 0.95

2 12 1.4e-05 0.00096 20.5 1.8 1 23 377 399 377 399 0.97

3 12 6e-06 0.00042 21.6 0.3 1 23 405 427 405 427 0.96

4 12 3.4e-05 0.0024 19.2 1.6 1 23 433 455 433 455 0.98

5 12 2.2e-05 0.0016 19.8 0.8 1 23 461 483 461 483 0.99

6 12 8.7e-06 0.00061 21.1 1.4 2 23 493 514 492 514 0.97

7 12 2.6e-05 0.0019 19.6 3.5 1 23 521 544 521 544 0.98

8 12 2e-06 0.00014 23.1 4.7 1 23 550 572 550 572 0.98

9 12 0.0032 0.22 13.1 2.2 1 23 578 600 578 600 0.98

10 12 0.00019 0.013 16.9 0.5 1 23 606 628 606 628 0.96

11 12 4.9e-06 0.00035 21.9 2.4 1 23 634 656 634 656 0.99

12 12 0.00084 0.059 14.9 2.0 3 23 664 685 662 685 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00037	0.026	16.0	1.3	2	22	350	370	349	370	0.95
2	12	1.4e-05	0.00096	20.5	1.8	1	23	377	399	377	399	0.97
3	12	6e-06	0.00042	21.6	0.3	1	23	405	427	405	427	0.96
4	12	3.4e-05	0.0024	19.2	1.6	1	23	433	455	433	455	0.98
5	12	2.2e-05	0.0016	19.8	0.8	1	23	461	483	461	483	0.99
6	12	8.7e-06	0.00061	21.1	1.4	2	23	493	514	492	514	0.97
7	12	2.6e-05	0.0019	19.6	3.5	1	23	521	544	521	544	0.98
8	12	2e-06	0.00014	23.1	4.7	1	23	550	572	550	572	0.98
9	12	0.0032	0.22	13.1	2.2	1	23	578	600	578	600	0.98
10	12	0.00019	0.013	16.9	0.5	1	23	606	628	606	628	0.96
11	12	4.9e-06	0.00035	21.9	2.4	1	23	634	656	634	656	0.99
12	12	0.00084	0.059	14.9	2.0	3	23	664	685	662	685	0.97

Sequence Information

Coding Sequence: atggAGATTGACGAAGTAACAAACAAAGAAGTGAAAACGACACATCAAACTCAAGATAACAGACTACACATTAAAGTCGAGGAAATAAGtattaaagaagaagaagaggattCCTACGAAAACAATGAATCAAATTGGGGTACGTTACCAGAAAAGGTACTGTCGATTAAATCTGAAGCTGCCTACACTTATTTAGATGGCAAACTAAACACGAATGACATTAAACAATCAATACCACACACTCAGGGTATTTTCGATAACCTCAATGTTTCAACACAAACCGAGCAAAATGGAAATAACATCAAAAGTAAAACCCCCAAATTTAGAAAAGataaaaAGATAAGTAAAAAGGGGTCCCTGCCGTTCAAAGATAACCTtcaaaaaaacgtcaaaaaggGATCGATACAACTGTGGCAATTCCTCATAACTTTGTTAGACGATCCAGGTAACGCCGCTATCATCAAATGGACTGGAAAAGGGATGGAGTTCAAGCTCGTCGATCCCGATGAAGTAGCCCGACGATGGGGACTTCAAAAAAACAGGTTAACGATGAACTACCAGAAACTAAGCAGGGCATTCAGGTACTATTATGAAAAAGGGATCATGAAGAAAGTTCAAGGAGGAATATATGTATACAAGTTCGTTTGTAATCCACAAATAATTTTGGAGACGGCGaacatgtttaaaaataagACAATTTCCATTCCTGAAAgcAATGCAACAAACTCGACTGTTGGTAAAGTAGAACAACAAAATTTCGACGACACTGATGATACATCAAGCAGCAAAAACGTTGTCAACAACCGAATTAAAAAGGAAACCATTGAAGAAATCAACGtaaaacaagaattaaaatttatcaccATCAACACATCAAACAGCAAAAATGTTGAAAGCCACGAAAACGTTCCAATTAAAACGGAAATCGTCGAATATATGGACGAAGAATCGCAATGGGACGAACCGGAGAGAGTCGAGATTCTATCGAGCAATCAACTCGCACAGGCAAAGCGAGACGAAGAAAGCTCAGACTCAGATTCGTACACGAAATGTAACGTTTGTAAAAAGACATTCGACACGGAACGTGATTTAGATCGCCATCAGAAAAAACCGTCCACCGACAAGACCTATGCGTGCTGCGCGTGTCCAAAGACGTTCCGAGACATGTCGCAGTTGAACGTTCACATGCGTAAACATACAGGTGAGAAGCCCTACGTGTGCATTGTATGCGGTAAGAAATTCTCGATAAAcggtaatttaaataaacacataCGCACTCACACCGGCGAGAGGAGATTCGAATGTGACGTTTGTGAAAGGAAGTTCACCCAGTTCGCACATCTGGAGGACCACGTAAAAACGCATTCCGGCGAACGGCCGTATCAGTGTGCCGAATGCGACAGTGCGTTTAAAACTAAAGCGCGACTTCGAAAACACATTAAATCccattcggaaaattttagaattaacaACGTTGAATGTCACCTTTGTCCGAAACGGTTTCGTAGTCAGTCGCAACTTGTCATTCACTTGAGTCGGCACACGGGTGAATCTCATCCTTTTAAGTGTATGGGTTGCGATAAGAAATTCACTGAATACAGTTACTTAAAAATGCAcatgaaaagaaaacattcGGGTATCAAAGCATACTCTTGCCATTTATGCGACAAAGGATTTGCCACCACGTCACATTTACGAAGGCACATCAAGTCGCATTCTGGCATTAAGCCGTACATGTGCGATATTTGTATGCGGGCTTTTCCGTGCCAGCAGAACTTGAAACGTCACATAAAAACCCATACAGGCGAAAAGCCTCATGCATGTCCGACGTGCCAAAAGGCATTTTTATCAATCGAAAATCTCAATAGGCACATACGAATTCACACGGGTGAAAAACCTTATCAGTGCAAAGAGTGCGGGAAATATTTTGCTCATAGCACTACAGTCAAAGAACATATGCGTATTCACACAGGGGAAAAGCCATTCGGATGTGGTGTGTGCAATAAAcattttgctttaaataaaatgttatacagACACATTCGAACGAGACACCCCGAACACGTTGATTCTTTGAGAGACATCATAAATCGACGGATTTCAACTGGGCAGCTAGTTAAATTTAAAACCGAAGTTGAAGACACGGTCGTCAACATAAAAAGGGAATTACCTGATTGTAAAGAAGATTCATAA
Protein Sequence: MEIDEVTNKEVKTTHQTQDNRLHIKVEEISIKEEEEDSYENNESNWGTLPEKVLSIKSEAAYTYLDGKLNTNDIKQSIPHTQGIFDNLNVSTQTEQNGNNIKSKTPKFRKDKKISKKGSLPFKDNLQKNVKKGSIQLWQFLITLLDDPGNAAIIKWTGKGMEFKLVDPDEVARRWGLQKNRLTMNYQKLSRAFRYYYEKGIMKKVQGGIYVYKFVCNPQIILETANMFKNKTISIPESNATNSTVGKVEQQNFDDTDDTSSSKNVVNNRIKKETIEEINVKQELKFITINTSNSKNVESHENVPIKTEIVEYMDEESQWDEPERVEILSSNQLAQAKRDEESSDSDSYTKCNVCKKTFDTERDLDRHQKKPSTDKTYACCACPKTFRDMSQLNVHMRKHTGEKPYVCIVCGKKFSINGNLNKHIRTHTGERRFECDVCERKFTQFAHLEDHVKTHSGERPYQCAECDSAFKTKARLRKHIKSHSENFRINNVECHLCPKRFRSQSQLVIHLSRHTGESHPFKCMGCDKKFTEYSYLKMHMKRKHSGIKAYSCHLCDKGFATTSHLRRHIKSHSGIKPYMCDICMRAFPCQQNLKRHIKTHTGEKPHACPTCQKAFLSIENLNRHIRIHTGEKPYQCKECGKYFAHSTTVKEHMRIHTGEKPFGCGVCNKHFALNKMLYRHIRTRHPEHVDSLRDIINRRISTGQLVKFKTEVEDTVVNIKRELPDCKEDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00740611;
90% Identity: iTF_00740611;
80% Identity: iTF_00740611;