Basic Information

Gene Symbol
-
Assembly
GCA_959613385.1
Location
OY390740.1:3878628-3880487[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 1.4e-05 0.001 20.4 4.6 1 23 116 138 116 138 0.99
2 18 7.7e-06 0.00054 21.3 3.8 1 23 144 166 144 166 0.98
3 18 0.00098 0.069 14.7 3.2 1 23 172 194 172 194 0.99
4 18 0.00026 0.019 16.5 8.8 1 23 200 222 200 222 0.99
5 18 4e-05 0.0029 19.0 0.3 1 23 228 250 228 250 0.96
6 18 3.7e-07 2.6e-05 25.4 0.7 1 23 256 278 256 278 0.99
7 18 2.8e-06 0.0002 22.6 2.4 1 23 284 306 284 306 0.98
8 18 5e-05 0.0036 18.7 4.2 1 23 312 334 312 334 0.98
9 18 2.1e-06 0.00015 23.0 2.6 1 23 340 362 340 362 0.99
10 18 0.00014 0.01 17.3 7.5 2 23 367 388 367 388 0.98
11 18 0.00017 0.012 17.1 5.9 1 23 394 416 394 416 0.99
12 18 3.6e-05 0.0026 19.2 2.3 1 23 422 444 422 444 0.99
13 18 5.4e-05 0.0038 18.6 4.9 1 23 450 472 450 472 0.98
14 18 0.00021 0.015 16.8 2.1 1 23 478 500 478 500 0.99
15 18 0.00015 0.01 17.2 2.0 1 23 506 528 506 528 0.99
16 18 7.3e-06 0.00052 21.3 3.4 1 23 534 556 534 556 0.99
17 18 9.5e-06 0.00067 21.0 7.1 1 23 562 584 562 584 0.99
18 18 1.4e-05 0.001 20.5 6.0 1 23 590 612 590 612 0.98

Sequence Information

Coding Sequence
ATGGATATTGATTCAAATGATTTCAACTCTGTTGTCGAAGTAAAATCTGAAACGGTGGAATGTACAACTTTATTCCCAAAACTGCAGTCTTGCTGTTTATTTCCTCCTACTGATGTTGATCATGAAGAAATGGAAGACACGCATATtgtaaaggaagaaaaatatgaaatttcacaAACTAGAATTGCACCCGATATCAAAATTAAGTTGGACGTCGGCGAGTACGACGATCCGTTGGACTCGAAACTTGTGTTGAAACATATCAATTTACACATCGAAGAAGAAATCCAAGATGATTTTGAAAGGAAAGACATCATAAATTGCACACGCACCAGCAAAATCAactacaagtgtgaaatttgtaacaaatgcttCGCAAAAAAACAATATCTCTCGCAACACGTCAAAACGCACAACGGAgagagaaattacaaatgcgacgtttgcagCAAATGCTTCTCAACGAAACCGCATCTATTGAGACACGTGGAAATACACACCggcaagaaaaattacaaatgcaacGTTTGCAAGAAACGCTTCCTAGATAGGCGATATCTATCGCAACACGTCAAAACACACGACaaggaaagaaattacaaatgcgaattttgcaagaaatgcttcaGAGACAACCGATATCTGTCACATCACGTCAAgacgcacaccggcgagagaaattacaaatgtgacgCGTGCAACAAATCTTACGCGACGAAACAAAATTTAGCTCGGCACGTCGAAGCGCACACCGGAGAGAGAAAGTACGAATGCAAAATATGCGGCAAACGTTACGCCACTAAAGAAAATCTACCACGACACATGAAAACGCACGCCGgggaaagaaatcacaaatgtgaaatttgcaagaaacgTTTCGCGACCAAAGACAATTTGTCGCAGCACGTCGAAACGCACGTCGgggaaagaaatcacaaatgcggcgtttgcaacaaatgtttcGCGAAGAAACAAAATCTATCAGTGCATCTCGAAACGCACGCCggggaaaaaaattataaatgcggCGTTTGCGACAAACGCTTCACGACAAAGGTGCAACTTTCGACGCACAAGAAAACACACACCGGGGAGAAtagatgtgaaatttgcaagaagtGCCTGTCGACTAAACAGCATCTCACGCAGCACATGAAaacgcacaccggcgagaaaaattacaaatgtgaactTTGCCACGTACGCTTCACAACTAAACAAAATCTATCGCGACATTTTAAAAGACACACTGGggaaagaaactacaaatgcgacgtttgcaaGAAACGTTTCGCGATGAAACAACACTTAATACAACACGTCGAAACGCACAACGCCGAGagaaatcacaaatgcgaaCTTTGCGACAAGCGATTCGCAACGAAGCAATATCTGACGCATCACGTCGAGACGCACGCCGcgggaaaaaattacaaatgtaaaatttgcgaGAAATATTTGAGAGGCAAACGGTATCTAGCTCGACACCTCAAAACGCACGTCGTTGAGAGGAATTATAAGTGCGAAGCTTGCGAGAAATGCTTCGTGGATAAAGGACGTCTAACTCAGCACGTTAAAATGCACGCCGACGATAGAGATTACAAATGTGACAAGTGTAACAAATGCTTCGTGACAAAACCGCAACTATCGCaacacgtcaaaatacacaacgaagatagaaattatgaatgtgaaatttgtaacaaatgcttCACGACGAAACATTATTTATCGCAACACCTCAAAAGGCACACCTTGGAAAGGAATCataaatgcgacgtttgcgaCAAGCGCTTCATGACAAAATCGCACCTATCACGACACGTCAAAAGTCACAATAGAGAGAGGGAGAAATTATAg
Protein Sequence
MDIDSNDFNSVVEVKSETVECTTLFPKLQSCCLFPPTDVDHEEMEDTHIVKEEKYEISQTRIAPDIKIKLDVGEYDDPLDSKLVLKHINLHIEEEIQDDFERKDIINCTRTSKINYKCEICNKCFAKKQYLSQHVKTHNGERNYKCDVCSKCFSTKPHLLRHVEIHTGKKNYKCNVCKKRFLDRRYLSQHVKTHDKERNYKCEFCKKCFRDNRYLSHHVKTHTGERNYKCDACNKSYATKQNLARHVEAHTGERKYECKICGKRYATKENLPRHMKTHAGERNHKCEICKKRFATKDNLSQHVETHVGERNHKCGVCNKCFAKKQNLSVHLETHAGEKNYKCGVCDKRFTTKVQLSTHKKTHTGENRCEICKKCLSTKQHLTQHMKTHTGEKNYKCELCHVRFTTKQNLSRHFKRHTGERNYKCDVCKKRFAMKQHLIQHVETHNAERNHKCELCDKRFATKQYLTHHVETHAAGKNYKCKICEKYLRGKRYLARHLKTHVVERNYKCEACEKCFVDKGRLTQHVKMHADDRDYKCDKCNKCFVTKPQLSQHVKIHNEDRNYECEICNKCFTTKHYLSQHLKRHTLERNHKCDVCDKRFMTKSHLSRHVKSHNREREKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-