Basic Information

Gene Symbol
-
Assembly
GCA_963576655.1
Location
OY755090.1:18115690-18117348[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 7e-05 0.0064 17.4 1.9 3 23 64 84 62 84 0.98
2 14 2.4e-06 0.00022 22.0 1.4 1 23 90 112 90 112 0.99
3 14 4.5e-05 0.0042 18.0 2.8 1 23 118 140 118 140 0.98
4 14 0.013 1.2 10.3 1.6 1 23 146 168 146 168 0.96
5 14 6.5e-05 0.0059 17.5 1.9 1 23 174 197 174 197 0.98
6 14 0.00019 0.018 16.0 0.7 1 23 203 225 203 225 0.98
7 14 3.5e-06 0.00032 21.5 2.7 1 23 231 253 231 253 0.98
8 14 0.00025 0.023 15.7 4.4 1 23 259 281 259 281 0.98
9 14 2.6e-05 0.0024 18.8 1.8 1 23 287 309 287 309 0.98
10 14 9.4e-06 0.00086 20.2 2.6 1 23 316 338 316 338 0.98
11 14 5.8e-05 0.0053 17.7 0.0 1 23 344 366 344 366 0.98
12 14 4.8e-05 0.0044 18.0 0.6 1 23 373 395 373 395 0.98
13 14 2.2e-05 0.002 19.0 1.2 2 23 402 423 401 423 0.97
14 14 9.1e-05 0.0083 17.1 0.2 1 23 429 451 429 451 0.98

Sequence Information

Coding Sequence
ATGGAGTATAATTGCACACGCGTTAATTTGCAGAAGGGAGATGAACCGTTCGAATGTGATAAATTTGAAATCAAAGATGAATTGATTATAGACACTGGCGAAAACTCTCTCGAATGCGATACAAAATTTTCGGAAACAGAAGGTCCAAATGAACACCGGGAAATGCATATTAACGAGTACCCCTTTGGATGTGATGTTTGTAATaagaaattcaagaagaaatgGCGATTAAAAGAACACCTCAGGATGCATACCGGCGAAAAACCGTTCAAATGCCAGATTTGCGGTGCGAAATTTTCGTACAAAAGGAGTTTAAAAGGTCACCAGAGGGTGCATACTGGCGAGAAACCGTTCGAGTGTGACATTTGTCACAAGAAATTCGGCTACAGAGGAAACTTCAAGTATCACCTCATGGTCCATACTGGCGAGAAACCGTTCGAGTGCGAAATTTGTATGAAGAAATTCAGCTGTAAAGGAAATTTGATACAACATCGTGTCGTGCACAATGGAGAAGACtcattcgaatgtgacatttgttACAGAAGGTTCACGCTTGAGAAATATTTGCGGCAACATCGTCGTACGGGACACACTGGGAACAAACCGTTCAGGTGTGATATTTGCTTTAGTGCGTTCAGTTATAGAAATCAGCTGACGGCGCACCTCATGTTGCACAACGGCGACAAGCCCTTCGAGTGCGAAGTTTGCCAAAAGAAATTCACTCAGCGATCCCACTGGGCACAACACCGTAGGGTACACACCGGCGAGCAGCCTTTCGAGTGCGACATCTGCAATAAAAAATTCGACTGCCAATCGCATCTGAACGACCATGTCAATACGCACACTGGTGAGAAGCCGTACGAATGCCGATTTTGCGAGAGAAAATTTGGGACCAGGGCAAGTTTGACGCGACACCTCAAGATGCATTCTGGAGAAAGAGGGAAATTTGAATGTCATATTTGCCAGAAGAAATATGGCTCGAAGAATTATTTGACCGCCCACATCAAAATGCACACCGGCGAAAAAACTTACGCTTGCGATATTTGCGGTAAAATATTGAGTACCGGCGGAAGCCTGGCGGTACACCGTAGGACGCACAGTGCTACTGACAATCGATTCGAATGCTATGTATGTCAGAAGAAATACGTCGCTAAGCAGAATCTGATAAGTCATATTAGAATGCACACTGAAGAAAAGCCATTGGagtgtgatatttgtaatgaaaaattcagacaCGAGGGCAACATGAAAGTACACCGTAGGATCCatgatgacaaaaaattatacgATTGTGAGATTTGTAGTAAGAAATTTGTACTAGAAGAAAGTTTGATAGATCACCGTCGTATGCACAATACTGAAGAATGCTATAATTGTCATCAACAGGTCGTTTCGAAACATTCAGTTGCACATACTGTTACTTACAGTAGTGAACAACATCTAGATCGACAAGAAACCTTTGAATATCATACTTGTGAGACGAATTATTGTTCAACACCGTCTTATCAAAATCAAGACAGCAAAGATTTTGATATGAGAAACTCTATGAAGTTCGAGCCTCCAATAGGAGAAAACTACAACACCGATGtcaaattcaagattgaatatgttgatttacaaatgaaggaaatagatgaaatgaaacaagaacATGTTTAG
Protein Sequence
MEYNCTRVNLQKGDEPFECDKFEIKDELIIDTGENSLECDTKFSETEGPNEHREMHINEYPFGCDVCNKKFKKKWRLKEHLRMHTGEKPFKCQICGAKFSYKRSLKGHQRVHTGEKPFECDICHKKFGYRGNFKYHLMVHTGEKPFECEICMKKFSCKGNLIQHRVVHNGEDSFECDICYRRFTLEKYLRQHRRTGHTGNKPFRCDICFSAFSYRNQLTAHLMLHNGDKPFECEVCQKKFTQRSHWAQHRRVHTGEQPFECDICNKKFDCQSHLNDHVNTHTGEKPYECRFCERKFGTRASLTRHLKMHSGERGKFECHICQKKYGSKNYLTAHIKMHTGEKTYACDICGKILSTGGSLAVHRRTHSATDNRFECYVCQKKYVAKQNLISHIRMHTEEKPLECDICNEKFRHEGNMKVHRRIHDDKKLYDCEICSKKFVLEESLIDHRRMHNTEECYNCHQQVVSKHSVAHTVTYSSEQHLDRQETFEYHTCETNYCSTPSYQNQDSKDFDMRNSMKFEPPIGENYNTDVKFKIEYVDLQMKEIDEMKQEHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-