Basic Information

Insect: Gastracanthus pulcherrimus
Gene Symbol: mecom-b
Assembly: GCA_949152435.1
Location: OX424574.1:183107134-183114014[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.013 3.7 10.5 0.6 2 23 278 300 277 300 0.93

2 8 0.00013 0.037 16.8 0.2 1 23 336 363 336 364 0.91

3 8 7.8e-06 0.0023 20.6 2.6 1 23 370 392 370 392 0.95

4 8 7.9e-05 0.023 17.5 5.3 1 23 398 420 398 420 0.99

5 8 0.74 2.2e+02 5.0 0.3 2 21 428 447 427 448 0.94

6 8 4.1e-08 1.2e-05 27.8 1.7 1 23 845 867 845 867 0.99

7 8 5.9e-07 0.00017 24.2 1.7 1 23 873 896 873 896 0.97

8 8 1.2e-05 0.0036 20.0 3.5 1 23 902 924 902 924 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.013	3.7	10.5	0.6	2	23	278	300	277	300	0.93
2	8	0.00013	0.037	16.8	0.2	1	23	336	363	336	364	0.91
3	8	7.8e-06	0.0023	20.6	2.6	1	23	370	392	370	392	0.95
4	8	7.9e-05	0.023	17.5	5.3	1	23	398	420	398	420	0.99
5	8	0.74	2.2e+02	5.0	0.3	2	21	428	447	427	448	0.94
6	8	4.1e-08	1.2e-05	27.8	1.7	1	23	845	867	845	867	0.99
7	8	5.9e-07	0.00017	24.2	1.7	1	23	873	896	873	896	0.97
8	8	1.2e-05	0.0036	20.0	3.5	1	23	902	924	902	924	0.99

Sequence Information

Coding Sequence: ATGCACCGAACGATTACCGGGGTTGCGACGGGGGGTGCGCGCACTGCACAGCGTACCGCGCACAAGGGAAAGAAGCTAAAGTTAAGTTGCGACTTGACTCGTGCGTTGGTGCCCGGTTCCCATGAAGGTCCGTTGGGGGTAAGTAGCCCGCCGCCATATGGCGGGCctagctcgctcgctcgcagcGGCGGACAAGTGCACCGGGGAGATTTAAATAACCGTTGGCCGGCCGCGAGATCGGAAGCTACGCCGACGAGCACTTCCCTCTTGTGTGTGTGTTCGGGACTATCCGCCCCGTATCACCGGCTCCCATACGAAGCTAATTTAACGAAGCGATCGGTCGGCACTAACAGTTATAGCTTAGCGCCTCGGCGACCATTGCCAGGCGGCAGAAGTCGTCGAGTCGGCCTCCTCCGCATCACGCGATGTTCGCCAGCGTCGCTTTGCGCTTGTGGGAAGGCAAGGTGTAGGAAAGACGAAGCGTTGCGATGGGACACGCAGGACGCGATTCGGCGGCGATTGGCCACCGGCTCGGCCGGCCCTTGCAGCCAATGGCGAGTCTCGGGGTTCCGGTCAGCCGGCCCGTGTATATATCCCACAGCCAGCGGCGGCCGCGGCGGCTTGCACCCCCGCCGAGACTCCTCTAACTGGAGCATCGCCGTGTTGTTGCGAAGCCTCTATTGTCTCTCGCGACGAGTTGTGTGTCGGATCGCCGCGACCGATCGGCTCCTCGCCGCACTTACTCCTCCACTTGCCAAAGAGGAAGTAGCTGGCATCTATGGTGCATCTCACGCCGACGAAGACAGGGAGGAAGACGAAGACGGAGAGACAAGGTGTACAGTCTGCGATAAACCATTCCAAGATATAGAAGTGCTCAACAAGCACCTCGTCGTCTGCCACCGATACCCGGCCCGCGAGCACTGCTGCTCCAGCTGTCCCAGCGGCTACGCCTGGAGGCCCCTCCTGGTGCGCCACCGCGCCACCGCCCACGGCGACGTGCGCAAGTACCCCTGCGAGAACTGCTCCAAGCCGGACGACCCGCAGGTCTTCACGGATCCGTCGAACCTCCAGCGGCACATCAGGGCCCACCACGTCGGGGCGCGCAGCCACGCCTGCACCGAGTGCGGCAAGACCTTCGCGACCAGCAGCGGTCTCAAGCAGCACACCCACATCCACAGCAGCTTCAAGCCTTTCCGGTGCGAGGTCTGCTTCAAGGCCTACACCCAGTTCTCGAACCTCTGCCGGCACAAGCGCATGCACGCCAAATGCCGCATGCAGATCACCTGCGCCAAGTGCAGCGCCCAGTTCCCCACCGGCACCTCGCTCTCCAAGCACAAGCGCTTCTGTGACTCGACCGCGCCCCAGCCCTCCTCGGCCTCCAGCATGCCGCAGCCCCAGCCCCAGCTCAACCCCTTCCTCTTCCCGCACCAGCCGCTCGGCTTCTATCCGCCGAGCCTCCTCGGAAACTACTCGGCCTCCTTCTTCCGCGGCACCGGCAATCGACTCGGCGTGCCGATGGTCTTCCCGCTCGAGCCCCACCGACAataccagcagcagcagcagcagcagcagcgtccgGAGAGTCCCGGGCAGGAGAGGCTCTCGCCGCCGAGGGCGGCGCCTCCTCCGGCACCGCCGGCCTTCCAGCGGATGCCCGCCGCGAGCAAGGTCTCGCCCTCCGCCGCCGAGGAGGCCACCTCCGGTCTGAGACCCTCGCCCGCTCGGCCGCCGCCCGCCTCGGCCCGGTCCGAGCCCGAGGAGCCCGCCAGCCCCAAGCCGCAGCCGCACAAGCGCAAGAGTCGGCCGAGCTCCGAGGAGCCGGAGCAGGACCAGCGCCAGACCGTCTCCGGCTCGGAGCAGCCCCTGGACCTGCGCGTGCAGACCAAGCGCAGGAGGATCGACGCGCCGCGGCCCGGCGACGCCCGGGAGGCCGAGCCCGAGGCCCGGCGGGAGCACTCGGAGCCCGAGGCCGCTCCCGAGAGAAGGCGCACCGAGTACTCGCCACCGCGGATCGCGCCCGAGGACCTGGCGACGACGAGCCAGCCTCGGCCCTGCAGCGGGCTCAAGGGCGAGAGGCAGCGCTCGGAGAGGCCGCCCTCGGAGAGCAAGGACCCGTCCAGCCCCGTCGCGCGGAGCGGCCCGCGGGTGCCGCCGGCCGAGAGTCCGCAGCGGGCCGAGAGGACGCCGCCGCCTCCGCCGCACATGGCCTACCCCAGGCCCATCCACCCGCTGTTCCTCGAGTCCATGTACCGCGCGTCGAACCCCTTCCCGAGCTTCCCGGACGTCGGGCCGGGAGCCGGGGCCCCGGCCGAGCACCGGCTGCTCCAGCCGATGCCGTCCTTCGGGCCCGCGCGCGGCCTGCCCTTCTTCGGGCCCCTCGTCAACGGCCTGGGCGGCCCCAGGCCCGCGGGCTACGACGTCCTGGCCAGACCCTCGCTGGCCGGCTTCCCCGGGGTCAAGCCCTTCCAGGACTCGGTGATGGGCCACCACCAGCCGAGCCCCTTCGCCGGCCACGCCAAGATCAAGGACCGCTACTCCTGCAAGTTCTGCGGCAAGAACTTCCCCAGGTCGGCGAACCTCACGCGGCACCTGCGCACCCACACCGGCGAGCAGCCCTACAAGTGCAAGTACTGCGAGCGCAGCTTCAGCATCTCCAGCAACCTGCAGCGCCACGTGCGCAACATCCACGACAAGCAGCGGCCCTTCAAGTGCCCGATGTGCGAGCGGTGCTTCGGCCAGCAGACGAACCTCGACCGGCACCTCAAGAAGCACGAGGCCGACGACGGCAGCGGCGTCGTCTCCGTGGCCGACTCGGCCGACAGCAGCAACGAGAACGAGCGCGAGGAGACCTCCACGTACTTCGACGAGATCCGCTCGTTCATGGGCAAGGTGACctacggcggcggcggcggtggggGCGGCGGCGTCGGCCTCGGGGACGCCCCCTACGGCCTGCCCCCGCATCACCCGGCCTACCTGCCGAGCCGACTGCGCGAGGTCCACGAGGCGCACGACCTCGTGGACGGCGTCCTCGGCAAGGGCAAGTACGAGGACGACGAGGACAGCGAGGACCGAGTGTCGCCCCTCGTGCCGGCGGACGCGCTCTCGCCCGTCGACCCGAAGCAGTCGCCCTCCTCGCAGTTCGATCTCAAGCTCAGCGGGAAGCGGGAGCTGCTCAACAACAACACGGCCGAGCCCGTCATCGAGATCTCGACATAG
Protein Sequence: MHRTITGVATGGARTAQRTAHKGKKLKLSCDLTRALVPGSHEGPLGVSSPPPYGGPSSLARSGGQVHRGDLNNRWPAARSEATPTSTSLLCVCSGLSAPYHRLPYEANLTKRSVGTNSYSLAPRRPLPGGRSRRVGLLRITRCSPASLCACGKARCRKDEALRWDTQDAIRRRLATGSAGPCSQWRVSGFRSAGPCIYPTASGGRGGLHPRRDSSNWSIAVLLRSLYCLSRRVVCRIAATDRLLAALTPPLAKEEVAGIYGASHADEDREEDEDGETRCTVCDKPFQDIEVLNKHLVVCHRYPAREHCCSSCPSGYAWRPLLVRHRATAHGDVRKYPCENCSKPDDPQVFTDPSNLQRHIRAHHVGARSHACTECGKTFATSSGLKQHTHIHSSFKPFRCEVCFKAYTQFSNLCRHKRMHAKCRMQITCAKCSAQFPTGTSLSKHKRFCDSTAPQPSSASSMPQPQPQLNPFLFPHQPLGFYPPSLLGNYSASFFRGTGNRLGVPMVFPLEPHRQYQQQQQQQQRPESPGQERLSPPRAAPPPAPPAFQRMPAASKVSPSAAEEATSGLRPSPARPPPASARSEPEEPASPKPQPHKRKSRPSSEEPEQDQRQTVSGSEQPLDLRVQTKRRRIDAPRPGDAREAEPEARREHSEPEAAPERRRTEYSPPRIAPEDLATTSQPRPCSGLKGERQRSERPPSESKDPSSPVARSGPRVPPAESPQRAERTPPPPPHMAYPRPIHPLFLESMYRASNPFPSFPDVGPGAGAPAEHRLLQPMPSFGPARGLPFFGPLVNGLGGPRPAGYDVLARPSLAGFPGVKPFQDSVMGHHQPSPFAGHAKIKDRYSCKFCGKNFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPMCERCFGQQTNLDRHLKKHEADDGSGVVSVADSADSSNENEREETSTYFDEIRSFMGKVTYGGGGGGGGGVGLGDAPYGLPPHHPAYLPSRLREVHEAHDLVDGVLGKGKYEDDEDSEDRVSPLVPADALSPVDPKQSPSSQFDLKLSGKRELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -