Basic Information

Gene Symbol
salm
Assembly
GCA_949825005.1
Location
OX463762.1:17928256-17938776[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 5.3e-06 0.0006 20.7 0.9 1 23 429 451 429 451 0.98
2 9 1e-05 0.0012 19.8 2.1 1 23 457 479 457 479 0.98
3 9 0.066 7.5 7.8 3.8 2 23 838 859 837 859 0.98
4 9 4.5e-08 5.2e-06 27.2 0.6 1 23 865 887 865 887 0.97
5 9 6.3e-05 0.0072 17.3 2.6 1 23 897 919 897 919 0.98
6 9 0.0022 0.25 12.5 1.9 2 23 1229 1250 1228 1250 0.97
7 9 0.038 4.3 8.6 1.0 1 14 1256 1269 1256 1270 0.92
8 9 6.1e-07 7e-05 23.7 2.1 3 23 1472 1492 1470 1492 0.96
9 9 2.1e-07 2.4e-05 25.1 0.9 1 23 1498 1520 1498 1520 0.98

Sequence Information

Coding Sequence
ATGCAACTGATGCGTTGGAGCATCACCCGTCGAATCGAGCAACACCGCGGGATCAAGCGCGAGGACGCTTTCGGCGCGCAGCGCTGTCAGTCGGATGCTGGTTCCGGTCCAGATTCCGGAGGAGACGACAATGAATACGCGTCGGACGGCGAGGAGAGCGCTGCTGGCGGCATCGGCGAGGAGGCTGTGGACCTCACGGCCTCGAGGTCCCACCACGGGGACGAGGACGACAAGGATCAGGAGGACCTGCCGCTGGATGAGGACGAGGAGGACGGCGAGGAGCACGAGGAgcaggacgacgacgaggagggATCTCGCAAGCAGATGCGGCATCGGCAGGACGCCgagaacaataacaatttcgTGGAGGGAGGAGGACCGCCGACTGGGATCTTCCCTCCAGCCGGCACTAGTCACGTCACTCTCGAGGCCCTCCAGAACACGAAAGTGGCGGTCGCCCAGTTTGCGGCCACGGCCCTGGCCGGGGGCGCCGATAGCGAGGCGGCCTTGCAAGACCTGGCGCTCCTGCAGAGCACCCTCTACACGCTGCAGCACCAGCAGGTCTTCCAGCTGCAGCTGATAAGCCAGTTGCAACAGCAGTTGTCGATAACCCACGCCGGGGGCCAGCCCATACCCGCGCAACAGCATCAAccgcagcaacagcagcaatcGCAAtcgcagcaacagcaacagcagcagctgcAATCCATTGGCTCGATAGGGGAGCACCCGACCCCATCGGATAGTAAGGAAACTTCGCCCTCTCCCGTGATACACCCCAAATCGTTATCCTCCTTGACGTCACCTCCCATCTCAAGACCGCCGTCGagtcaccatcatcatcagcagcagcagcagcatcagcatcagcatcatcaACAAACGTCGACGTCGCCGCTCACGCCGAACGTGGCCCAGGAGCGGCCCACTCCGACGAGCAGCGCCTCGCCCTTGAGCCTCTCGATACCGAGCGTTTCGAGCGTGACCGTGCAAACCACCACGGCCAGCAGCCAAGTACCGCTACCGCATCAAATGCCGCCGTTGTGCTCTATAAGCTCGTCGCTCGCCTCGTCGATCATCACGAACACGGATCCCCCGCCGCTTCACGAACCCAACACCCTGGAGATGTTACAGAAACGGGCTCAGGAAGTGCTGGATAACGCGAGCCAAGGTCTCCTGGCCAATAACCTGGCCGACGAGCTGGCCTTCAGGGGAGGTAAGGGTTCTCGGTTGTCGCCGTATGACTCCAAGTCCGGCGGGGGTCGTGGCGAGCCGTTCTTCAAACATCGGTGTCGTTACTGCGGCAAGGTCTTTGGAAGTGACTCGGCTCTTCAGATCCACATACGATCCCATACAGGTGAGCGACCATTTAAATGCAACGTCTGTGGAAGCCGATTCACCACCAAAGGGAACCTCAAAGTTCACTTTCAGAGGCACACGGCCAAGTTTCCACATGTAAAGATGAACCCGAACCCCGTGCCCGAACACCTTGACAAGTATCACCCACCTCTCCTACAGCAGCTCGCGGCTTCGGGCCAAAGACCGTTACCATCCCCTCCGCCTCCGCCCCATCCACCGTTTCATCCCGCGGCGACTCACGGGTTTCTTCCGCCACAACCGCCCCTGCCCCTGAGTCTCACGTTGCCCGGTATGCCACCCCTCTACCGTTCTCCAATCGTTAACCACAGAGACGATCAAGACGTACCGGAAAACCTCAGTAAGCCTGTAACGACAGCTTCGGCCGCGACCTCTCCACAATCACCCACGACACATTCGAATTCTCGCCATTCCTTTCACGACAATCACCAACAGATAGCACTGCAAGAGGACAAAAGCAGTGATATCAAGGTCGAGCAGCAATCTCCGTTGCAAGAGCAGTATCACCAGCGGTCCGTCAGCCGGGAGGGCGAAGAGATTACACCCAAGAGGGAGCCGGTCGAGCCGGAGGAGCAGCCCGAGGACGAGGCCGAGGAGTACGAGGACAACTCCCGTCGGTACCTCAGCTCCCCTCAATCCTCCGTTAACCCACCGTCGCATCCTCAGACGTACGAGGACTGCAGCATGGATAGCAAAATTAGCGGTCGCTTGGAGGCCGACGGCGAGATGGACGTCGACGAAGAAATGGAGGAGCAACCGGAGAATCTGTCCAGCAGAGCCACGGCGAACCGTCTACCTCAGCCGATGATGGCCTACCCCGGAGCCTCGCCGGCCAGCAGTAGCGCCAGCAGCGGTAGCCTGCAGACGTCCTTCGCGGGGATCCTCTTTCCCGGACCTCCGCAGCATCACCAACTGCCCCATCATCCGCCGACCACGGGCACCACCCCCACGGGCTCCACGAACGAGATGATCGTCGACCCGGCGAGGGACCCCGCGATCTATTCCAGTCTCCTGCCACGACCCGGCAGCAACGACAACTCCTGGGAGAGTCTCATCGAGATCACGAAAACCTCGGAGACGTCCAAGTTGCAGCAGCTGGTCGACAACATCGAGCACAAACTCACGGATCCCAACCAGTGCGTCATCTGCCACCGGGTGCTCTCCTGCAAGAGCGCGTTGCAGATGCACTATCGCACGCACACCGGCGAGCGTCCGTTCAAGTGCAAGATCTGCGGCCGAGCGTTCACTACCAAAGGAAACCTCAAGACTCACATGGGGGTGCATCGCGCGAAGCCGCCCCTGAGGGTGTTGCACCAGTGTCCCGTGTGCCACAAGAAGTTCACGAACGCGCTGGTGCTGCAGCAGCACATCCGACTGCACACCGGGGAACCCACGGATCTCAGCCCGGAGCAGATACAGGCGGCGGAAGTGAACGAATTCCCACCGGGGTATCCCCATCATCCCTTGGCTTCGTTCCTACCTCAAGGCTTCCCGCCGTTGCATCCCGCCGGTGCAAGCTTCTCTTTGGGGTTCCCACCCTCCAGGCACCACCCCATCGAGCGGCACCAGCCGGAGAACGACTCGGAGATGAAAGAGGAGGCTGAGCACCAccatcagcagcagcagaggTACATGGACGAGCACGTGGACGAGATGGACGACcaggacgacgaggacgaagACCGGCGGGAGGACGACGAGCGAAGCGACACGAATCGAGATCGTCAGAGCGTCGACGTCGACCCCGAGGAGGAGCAGGAAGCCGAGAACGAGGAGCTCCTCGAACAGAAGGAACACATATCTCTGCCGGCGTCGTTCTCGACGTCACTGGCGGCGCTGGAGAACCAAGTGAGGACCATCACCACCACCGTGGCGGCTAGCAACGCCGCCAGCGGAATCGCCAGGTCACCACCCTTCCATCGTTATAACGGCAGCGACAAGAGCACTAGTCCGCCGAGCGCCGGGGCACCGCTCGACCTGACCCCGCGAGCATCCTCGACGCCAGCGTCCTCGGCCTCGACGCCACCACCACAGCCAACGGCCTCGCAGCATCCGCATCCCTTCGGCATGTTTGCCGGGCTCCTGCAGGCCGTGTCGTCCTCGCCGACGCATAACACCATGAGCACCACCAGTGGAAGCGTGAATACCGCGGCTTCCGTTAGTCCGGGAAACGGAGGtagtggaggaggaggaggaggaggaggaggacctTTAGCTTCCTTAACCACGTCAGCCGTTCTTGCCGCAACTTCAACATACAATCCGCTAGGCCTGGCTGTCGGAGGGCCAGCAGTCCGTGGCAACACCACGTGTAATATCTGCTACAAGACATTCGCGTGCAACTCGGCACTGGAGATCCATTATCGGAGTCATACGAAGGAACGGCCCTTTAAATGCAGCATATGCGACCGAGGTTTCTCGACAAAGAACGACGGTTCGCAGCTGGAAGTATGCTCTTGCGCGGAGCCACGAAACAGCTATTCCGTCAAGAGTACTTCTACCTCCACCGCCGACACCTCTCAAATCACTCCTCTAAACAAAACAGCCTCCACTGATGATCAACCGAAGACGAGTCGCAGGCGGCGAAGGACTGAGGAGCGGAAGACCCGGGGGCGGTCTGGGACTGACGGGGGGCGGGCGCTGACGTCCGCGTTTGCTGCCGTCCACCTGCCCCCGATGATGCCGCCCGCCCTCGGACTTCTTACCTCGGACCACGTCTTCCTGGGGAACATGAAACAGCACATGCTGACCCACAAGATACGCGACATGCCTCCGCATCTCTTCAGCGACGCGAAACAGCCTggccagcagcagcagcagcagcagtcgTCGCAGGATCTTGAGGGATCGAGAAGTCCCATGTGCTCGGACGACTCGAGTTTGCCGCCTCCGCCGCCACCGCCGCCGCCACCACCGCCTCCGCCGCCACCCTTGCCACCGACGTCGGTGGAAGCAACAACCCCCGTGAAGAGATCGCCTCCAGAAGGGGACCTCCCGGCACCGAAAAGGCCGTCCAGCATGTCCAGCAAGCACTTGTGCCAGATTTGCAATAAGAATTTCTCGTCATCTTCGGCGCTCCAGATCCATATGAGAACTCACACGGGCGACAAACCGTTCCGATGCACCGTCTGCCAGAAGGCCTTCACCACCAAGGGCAATCTCAAGGTACACATGGGCACCCATATGTGGACCAACGGAGCATCCCGGCGAGGACGTCGAATGTCGCTGGACCTGCCACCGCTCCCCATCACGCCCAAGGACTCGGAGTTTCTTCAGCGACGACCGGATCTTTTCTATCCATATCTCCCCGCGCCGTTCCTTAATGGCGTTCAGCAGAAACTGAACGAGATATCGGTGATCCAAAGCAACAACGGCCTCCCGGCGGCGCACTCCGTCAACGCCGGCAAGTACGGCCTCTTCGGGAGCGTTTACGGCGGCGGTGGCTTCCCGCTGGACAAGCAGCCGATGGCTCCGAGCAACGGGCCGCTGGTCGACGGCAAATCGGCCATCCCGTCCGGCTCGATACTCTTCCAGACGCCCTCGCCCTCGCACTCGCCCGGCACGCCGTCGTCCAACACCGGCAACCAGAATTCGGCGAGCGTTCCCTCCTGGACCGGAGACGCCCTGCAGCATCCCTTCGTGGACCGGGAAGCGCCGTCAAGGCCGGAGAACGACAGCAGTCCGCCAAGTGCTCGGCTGCCTCCTCCACCGGCCGCTCGGGGTGAAGGTCTGGCGGCGTAG
Protein Sequence
MQLMRWSITRRIEQHRGIKREDAFGAQRCQSDAGSGPDSGGDDNEYASDGEESAAGGIGEEAVDLTASRSHHGDEDDKDQEDLPLDEDEEDGEEHEEQDDDEEGSRKQMRHRQDAENNNNFVEGGGPPTGIFPPAGTSHVTLEALQNTKVAVAQFAATALAGGADSEAALQDLALLQSTLYTLQHQQVFQLQLISQLQQQLSITHAGGQPIPAQQHQPQQQQQSQSQQQQQQQLQSIGSIGEHPTPSDSKETSPSPVIHPKSLSSLTSPPISRPPSSHHHHQQQQQHQHQHHQQTSTSPLTPNVAQERPTPTSSASPLSLSIPSVSSVTVQTTTASSQVPLPHQMPPLCSISSSLASSIITNTDPPPLHEPNTLEMLQKRAQEVLDNASQGLLANNLADELAFRGGKGSRLSPYDSKSGGGRGEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVHFQRHTAKFPHVKMNPNPVPEHLDKYHPPLLQQLAASGQRPLPSPPPPPHPPFHPAATHGFLPPQPPLPLSLTLPGMPPLYRSPIVNHRDDQDVPENLSKPVTTASAATSPQSPTTHSNSRHSFHDNHQQIALQEDKSSDIKVEQQSPLQEQYHQRSVSREGEEITPKREPVEPEEQPEDEAEEYEDNSRRYLSSPQSSVNPPSHPQTYEDCSMDSKISGRLEADGEMDVDEEMEEQPENLSSRATANRLPQPMMAYPGASPASSSASSGSLQTSFAGILFPGPPQHHQLPHHPPTTGTTPTGSTNEMIVDPARDPAIYSSLLPRPGSNDNSWESLIEITKTSETSKLQQLVDNIEHKLTDPNQCVICHRVLSCKSALQMHYRTHTGERPFKCKICGRAFTTKGNLKTHMGVHRAKPPLRVLHQCPVCHKKFTNALVLQQHIRLHTGEPTDLSPEQIQAAEVNEFPPGYPHHPLASFLPQGFPPLHPAGASFSLGFPPSRHHPIERHQPENDSEMKEEAEHHHQQQQRYMDEHVDEMDDQDDEDEDRREDDERSDTNRDRQSVDVDPEEEQEAENEELLEQKEHISLPASFSTSLAALENQVRTITTTVAASNAASGIARSPPFHRYNGSDKSTSPPSAGAPLDLTPRASSTPASSASTPPPQPTASQHPHPFGMFAGLLQAVSSSPTHNTMSTTSGSVNTAASVSPGNGGSGGGGGGGGGPLASLTTSAVLAATSTYNPLGLAVGGPAVRGNTTCNICYKTFACNSALEIHYRSHTKERPFKCSICDRGFSTKNDGSQLEVCSCAEPRNSYSVKSTSTSTADTSQITPLNKTASTDDQPKTSRRRRRTEERKTRGRSGTDGGRALTSAFAAVHLPPMMPPALGLLTSDHVFLGNMKQHMLTHKIRDMPPHLFSDAKQPGQQQQQQQSSQDLEGSRSPMCSDDSSLPPPPPPPPPPPPPPPPLPPTSVEATTPVKRSPPEGDLPAPKRPSSMSSKHLCQICNKNFSSSSALQIHMRTHTGDKPFRCTVCQKAFTTKGNLKVHMGTHMWTNGASRRGRRMSLDLPPLPITPKDSEFLQRRPDLFYPYLPAPFLNGVQQKLNEISVIQSNNGLPAAHSVNAGKYGLFGSVYGGGGFPLDKQPMAPSNGPLVDGKSAIPSGSILFQTPSPSHSPGTPSSNTGNQNSASVPSWTGDALQHPFVDREAPSRPENDSSPPSARLPPPPAARGEGLAA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-